Pain 2021 Apr 12. Epub 2021 Apr 12.
Lotus Clinical Research, Pasadena, CA, United States JBR Clinical Research, Salt Lake City, UT, United States Dr Reddy's Laboratories, Princeton, NJ, United States.
Abstract: The analgesic efficacy and safety of DFN-15, a new oral liquid formulation of celecoxib with more rapid absorption than the capsule, were evaluated in the treatment of acute pain in adult patients after dental surgery. In this randomized, double-blind, placebo-controlled, dose-ranging study, 120 otherwise healthy adults who underwent the extraction of bilateral impacted mandibular third molar teeth and experienced moderate to severe pain postsurgery were randomly assigned, in a 1:1:1:1 ratio, to receive one dose of either placebo or DFN-15 at 3 doses: 62.5, 125, and 250 mg. Read More