8,222 results match your criteria thin skin


Implant-based immediate reconstruction in prophylactic mastectomy: is the caudal dermis flap a reliable alternative to synthetic mesh or acellular dermal matrix?

Arch Gynecol Obstet 2021 Sep 23. Epub 2021 Sep 23.

Department of Plastic Surgery, University Hospital Regensburg, Regensburg, Germany.

Introduction: The demand for prophylactic mastectomy has increased significantly over the last 10 years. This can be explained by a substantial gain of knowledge about the clinical risk and outcome of patients with high risk mutations such as BRCA1 and 2, the improved diagnostic possibilities for detecting the genetic predisposition for the development of breast cancer and the awareness for those mutations by health care professionals as well as patients. In addition to expander-to-implant reconstruction and microsurgical flap surgery, definitive immediate reconstruction with subpectoral insertion of breast implants is often preferred. Read More

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September 2021

Wearable Thermoelectric Devices Based on Three-Dimensional PEDOT:Tosylate/CuI Paper Composites.

ACS Appl Mater Interfaces 2021 Sep 21. Epub 2021 Sep 21.

Department of Chemistry, University of Massachusetts Lowell, Lowell, Massachusetts 01854, United States.

Thermoelectric composites of organic and inorganic materials exhibit significantly enhanced thermoelectric properties compared with pristine organic thermoelectrics so they might be better suited as core materials of wearable thermoelectric devices. This study describes the development of three-dimensional (3D) paper PEDOT:tosylate/CuI composites that could be shaped as 3 mm thick blocks to convert a temperature difference between their bottom and top sides into power; the majority of organic thermoelectric materials are shaped as thin strips usually on a planar substrate and convert a temperature difference between the opposite edges of the strips into power. The 3D paper PEDOT:tosylate/CuI composites can produce a power density equal to 4. Read More

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September 2021

A low voltage-powered soft electromechanical stimulation patch for haptics feedback in human-machine interfaces.

Biosens Bioelectron 2021 Sep 8;193:113616. Epub 2021 Sep 8.

Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, 518055, China; Berkeley Sensor & Actuator Center, University of California at Berkeley, Berkeley, CA, 94720, USA; Department of Mechanical Engineering, University of California at Berkeley, Berkeley, CA, 94720, USA. Electronic address:

One grand challenge in haptic human-machine interface devices is to electromechanically stimulate sensations on the human skin wirelessly by thin and soft patches under a low driving voltage. Here, we propose a soft haptics-feedback system using highly charged, polymeric electret films with an annulus-shape bump structure to induce mechanical sensations on the fingertip of volunteers under an applied voltage range of 5-20 V. As an application demonstration, a 3 × 3 actuators array is used for transmitting patterned haptic information, such as letters of 'T', 'H', 'U' letters and numbers of '0', '1', '2'. Read More

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September 2021

"TO AND FRO" BLOOD FLOW MATHEMATICAL MODEL IN VENOUS FLAP SURVIVAL.

Wiad Lek 2021 ;74(8):1960-1963

PRIVET HIGHER EDUCATIONAL ESTABLISHMENT «KYIV MEDICAL UNIVERSITY», KYIV, UKRAINE.

Objective: The aim of the research is to determine "to and fro" venous flap blood circulation perfusion ability and flap size survival.

Patients And Methods: Materials and methods: "To and fro" blood circulation mathematical model based on the theory of compressed liquid flow thought the porous medium.

Results: Result: Designed mathematical model allows to calculate the viable flap size that depends on pedicle vessel radius, the blood pressure gradient, the blood viscosity, the elastic tissue capacity, the pulse frequency, vessels flap topography and surgical pedicle flap technique. Read More

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September 2021

Temporal trend of small nerve fibre degeneration in people with and without type 2 diabetes mellitus.

Diabet Med 2021 Sep 18:e14691. Epub 2021 Sep 18.

Department of Translational Medicine, Hand Surgery, Lund University, Malmö, Sweden.

Aims: We investigated the long-term temporal trend of intraepidermal nerve fibre density (IENFD) and the association between changes in IENFD and metabolic factors in individuals with and without type 2 diabetes.

Methods: A total of 66 participants were enrolled in this longitudinal population-based study, at baseline consisting of 35 individuals (median 61 years) without diabetes and 31 individuals with type 2 diabetes mellitus. Participants underwent clinical and electrophysiological examinations, as well as a skin biopsy both at baseline and at the follow-up visit (mean 8. Read More

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September 2021

Hidden penis: a rare case of delayed complication after a pelvic blunt trauma.

Transl Androl Urol 2021 Aug;10(8):3524-3528

Department of Urology, Marche Polytechnic University, Ancona, Italy.

Penile dislocation following a traumatic pubic bone fracture is a very rare condition. Only a few cases are reported in the literature and the presentation mechanism is still not completely understood. The impact energy on the pelvis usually causes a displaced fracture with concomitant withdrawal of the pubic bone. Read More

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Trends in the characteristics of skin melanoma in accordance with time intervals: A single Turkish tertiary referral center experience.

J Cancer Res Ther 2021 Jul-Sep;17(4):1119-1122

Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey.

Aim: The incidence of skin melanoma has increased dramatically in recent years. The aim of this study was to analyze the trends in the features of Turkish cutaneous melanoma patients in a 25-year period.

Materials And Methods: A total of 1258 adult melanoma patients who had been managed and followed up at a tertiary referral center between 1993 and 2017 were included in the study. Read More

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September 2021

Non-linear convective flow of the thin film nanofluid over an inclined stretching surface.

Sci Rep 2021 Sep 15;11(1):18410. Epub 2021 Sep 15.

Applied Mathematics for Science and Engineering Research Unit (AMSERU), Program in Applied Statistics, Department of Mathematics and Computer Science, Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi, Thanyaburi, Pathumthani, 12110, Thailand.

To enhance the surface properties of solids the mechanism of thin films is frequently used. Penetration, degradation, stiffness, illumination, diffusion, absorption, and electric performance are all characteristics of a bulk substance medium that a thin film can improve. In nanotechnology, thin film processing can be extremely useful. Read More

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September 2021

[Free transplantation of medial plantar Flow-through venous flap for primary repairing children's finger wounds with digital artery defect].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Sep;35(9):1182-1185

Department of Burn and Plastic Surgery, the Affiliated Hospital of Zunyi Medical University, Zunyi Guizhou, 563003, P.R.China.

Objective: To explore the feasibility and effectiveness of free transplantation of medial plantar Flow-through venous flap for primary repairing children's finger wounds with digital artery defect.

Methods: Between July 2016 and October 2020, 9 children who suffered finger wounds with digital artery defect were primary repaired with free transplantation of medial plantar Flow-through venous flap. There were 6 boys and 3 girls, with an average age of 6. Read More

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September 2021

Celastrol Niosome Hydrogel Has Anti-Inflammatory Effect on Skin Keratinocytes and Circulation without Systemic Drug Exposure in Psoriasis Mice.

Int J Nanomedicine 2021 4;16:6171-6182. Epub 2021 Sep 4.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, People's Republic of China.

Purpose: Psoriasis is an inflammatory skin disease, where keratinocytes play pivotal roles in its pathogenesis. We prepared Celastrol Noisome hydrogel (Cel Nio gel) for the treatment of psoriasis and aimed to study its target site as well as the mechanism.

Methods: Cel Nio was fabricated with thin-film hydration and sonication, then topically administered to imiquimod (IMQ)-induced psoriasis mice. Read More

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September 2021

Anal Atresia in a Patient Who Had Undergone Hartmann Procedure.

Am J Case Rep 2021 Sep 11;22:e932764. Epub 2021 Sep 11.

Department of Surgery, National Hospital Organization, Higashihiroshima Medical Center, Hiroshima, Japan.

BACKGROUND Hartmann procedure can be necessary for the treatment of rectal cancer and colonic perforation. The distal diverted intestinal tract is usually disregarded, while the proximal colon is diverted with a stoma. Most of the reported complications related to a diverted intestinal tract following Hartmann procedure include inflammation and intestinal tumors; however, there are only a few reports about postoperative anal complications. Read More

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September 2021

Design of long acting invasomal nanovesicles for improved transdermal permeation and bioavailability of asenapine maleate for the chronic treatment of schizophrenia.

Int J Pharm 2021 Sep 15;608:121080. Epub 2021 Sep 15.

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Asenapine Maleate (ASPM) is a second generation antipsychotic used for the management of schizophrenia but with very limited oral bioavailability due to its extensive first pass metabolism. Transdermal administration of ASPM using nanocarriers like invasomes might offer an excellent alternative to its oral administration with enhanced bioavailability and a sustained action. ASPM-loaded invasomes were successfully prepared by thin film hydration technique; meanwhile the penetration enhancing effect of terpenes (cineole and limonene) was compared to hydromiscible cosolvent (Transcutol®). Read More

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September 2021

On the Effectiveness of Impedance-Based Fingerprint Presentation Attack Detection.

Sensors (Basel) 2021 Aug 24;21(17). Epub 2021 Aug 24.

da/sec-Biometrics and Internet Security Research Group, Hochschule Darmstadt, 64295 Darmstadt, Germany.

Within the last few decades, the need for subject authentication has grown steadily, and biometric recognition technology has been established as a reliable alternative to passwords and tokens, offering automatic decisions. However, as unsupervised processes, biometric systems are vulnerable to presentation attacks targeting the capture devices, where presentation attack instruments (PAI) instead of bona fide characteristics are presented. Due to the capture devices being exposed to the public, any person could potentially execute such attacks. Read More

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Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile.

Autophagy 2021 Sep 7:1-15. Epub 2021 Sep 7.

Department of Dermatology, Medical University of Vienna, Vienna, Austria.

Preputial glands are large lipid and hormone secreting sebaceous organs of mice, and present a convenient model for the investigation of biological processes in sebocytes. Suppression of ATG7-dependent macroautophagy/autophagy in epithelial cells of murine skin causes enlargement of hair follicle-associated sebaceous glands and alters the lipid profile of sebum. We have now extended these studies to the preputial glands and find that autophagy significantly delays the onset of age-related ductal ectasia, influences lipid droplet morphology and contributes to the complete dissolution of the mature sebocytes during holocrine secretion. Read More

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September 2021

Are Contact Angle Measurements Useful for Oxide-Coated Liquid Metals?

Langmuir 2021 Sep 7;37(37):10914-10923. Epub 2021 Sep 7.

Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, 27695 North Carolina, United States.

This work establishes that static contact angles for gallium-based liquid metals have no utility despite the continued and common use of such angles in the literature. In the presence of oxygen, these metals rapidly form a thin (∼1-3 nm) surface oxide "skin" that adheres to many surfaces and mechanically impedes its flow. This property is problematic for contact angle measurements, which presume the ability of liquids to flow freely to adopt shapes that minimize the interfacial energy. Read More

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September 2021

Suppressing Interface Strain for Eliminating Double-Slope Behaviors: Towards Ideal Conformable Polymer Field-Effect Transistors.

Adv Mater 2021 Sep 4:e2101633. Epub 2021 Sep 4.

Center for Advanced Optoelectronic Functional Materials Research and Key Lab of UV-Emitting Materials and Technology of Ministry of Education, Northeast Normal University, Changchun, 130024, China.

High-mobility polymer field-effect transistors (PFETs) are being actively explored for applications in soft electronic skin and low-cost flexible displays because of their superior solution processability, mechanical flexibility, and stretchability. However, most of high-mobility PFETs often deviate from the idealized behavior with variable mobility, large threshold voltage, and high off-state current, which masks their intrinsic properties and significantly impedes their practical applications. Here, it is first revealed that interface strain between polymer thin film and rigid substrate plays a crucial role in determining the ideality of PFETs, and demonstrate that various ideal conformable PFETs can be successfully fabricated by releasing strain. Read More

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September 2021

Systems of conductive skin for power transfer in clinical applications.

Eur Biophys J 2021 Sep 3. Epub 2021 Sep 3.

Department of Mechanical and Process Engineering, Institute for Mechanical Systems, ETH Zurich, Leonhardstrasse 21, 8092, Zurich, Switzerland.

The primary aim of this article is to review the clinical challenges related to the supply of power in implanted left ventricular assist devices (LVADs) by means of transcutaneous drivelines. In effect of that, we present the preventive measures and post-operative protocols that are regularly employed to address the leading problem of driveline infections. Due to the lack of reliable wireless solutions for power transfer in LVADs, the development of new driveline configurations remains at the forefront of different strategies that aim to power LVADs in a less destructive manner. Read More

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September 2021

Association between melanoma thickness and clinical and demographic characteristics.

Eur J Dermatol 2021 Aug 26. Epub 2021 Aug 26.

Dermatology Department. Instituto Valenciano de Oncología. València, Spain, School of Medicine. Universidad Católica de Valencia San Vicente Mártir, València, Spain.

The large-scale implementation of primary and secondary skin cancer prevention strategies in recent decades has led to an increase in the diagnosis of thin melanomas and a decrease in the mean thickness of tumours diagnosed. The number of newly diagnosed thick melanomas, however, has remained stable. To investigate associations between melanoma thickness, clinical presentation and demographic and phenotypic characteristics. Read More

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Iterative optical technique for detecting anti-leishmania nanoparticles in mouse lesions.

Biomed Opt Express 2021 Jul 28;12(7):4496-4509. Epub 2021 Jun 28.

Faculty of Engineering, Bar Ilan University, Ramat Gan 5290002, Israel.

Nanoparticles (NPs) based drugs for topical administration are gaining interest in the biomedical world. However, a study tool of their penetration depth to the different tissue layers without additional markers or contrast agents is required in order to relieve safety concerns. While common diagnostic tools, e. Read More

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Improving and evaluating the adhesion and stability of make-up by enhancing the affinity between skin/make-up layer.

Skin Res Technol 2021 Aug 29. Epub 2021 Aug 29.

LG Household & Health Care (LG H&H), LG Science Park R&D Center, Seoul, Republic of Korea.

Purpose: upMake-up clumps, bumps and collapses are the three factors that determine how well make-up has been performed. The purpose of this study is to reduce the three factors mentioned above by using amphiphilic substances to increase the affinity between the skin and the make-up layer. In addition, it aims to evaluate the improvement of the make-up layer by developing an objective make-up layer evaluation method. Read More

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Analysis of Tilt Effect on Notch Depth Profiling Using Thin-Skin Regime of Driver-Pickup Eddy-Current Sensor.

Sensors (Basel) 2021 Aug 17;21(16). Epub 2021 Aug 17.

School of Electrical and Electronic Engineering, University of Manchester, Sackville Street Building, Manchester M13 9PL, UK.

Electromagnetic eddy current sensors are commonly used to identify and quantify the surface notches of metals. However, the unintentional tilt of eddy current sensors affects results of size profiling, particularly for the depth profiling. In this paper, based on the eddy current thin-skin regime, a revised algorithm has been proposed for the analytical voltage or impedance of a tilted driver-pickup eddy current sensor scanning across a long ideal notch. Read More

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Rare complication of cushing's syndrome in the elderly: a case report.

Endocrine 2021 Aug 26. Epub 2021 Aug 26.

Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.

Purpose: Cushing's syndrome (CS) is a rare and severe disease caused by sustained hypercortisolism. The clinical manifestations of CS can be atypical in the elderly, and the diagnosis in these patients is often missed. Infectious Purpura Fulminans (PF) is a life-threating, thrombotic form of disseminated intravascular coagulation with high mortality. Read More

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Dermoscopic Criteria, Histopathological Correlates and Genetic Findings of Thin Melanoma on Non-Volar Skin.

Genes (Basel) 2021 Aug 23;12(8). Epub 2021 Aug 23.

Surgical Pathology, Galliera Hospital, 16128 Genoa, Italy.

Dermoscopy is a non-invasive, in vivo technique that allows the visualization of subsurface skin structures in the epidermis, at the dermoepidermal junction, and in the upper dermis. Dermoscopy brought a new dimension in evaluating melanocytic skin neoplasms (MSN) also representing a link between clinical and pathologic examination of any MSN. However, histopathology remains the gold standard in diagnosing MSN. Read More

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Phytochemical Study and In Vitro Screening Focusing on the Anti-Aging Features of Various Plants of the Greek Flora.

Antioxidants (Basel) 2021 Jul 28;10(8). Epub 2021 Jul 28.

Division of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.

Skin health is heavily affected by ultraviolet irradiation from the sun. In addition, senile skin is characterized by major changes in the collagen, elastin and in the hyaluronan content. Natural products (NPs) have been shown to delay cellular senescence or in vivo aging by regulating age-related signaling pathways. Read More

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Flavonoids and saponins from Passiflora edulis f. edulis leaves (purple passion fruit) and its potential anti-inflammatory activity.

J Pharm Pharmacol 2021 Aug 26. Epub 2021 Aug 26.

Universidad Nacional de Colombia, Sede Bogotá, Facultad de Ciencias, Departamento de Química, Bogotá, Colombia.

Objectives: The objective of this work was to evaluate the anti-inflammatory activity of the aqueous extract, fractions and major compounds, which are isolated and identified from Passiflora edulis f. edulis (purple passion fruit) leaves extract.

Methods: For the isolation of the major compounds, reversed-phase chromatography and normal phase countercurrent chromatography were used. Read More

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Hyperdynamic Valve: A Rare Case of Ehlers-Danlos Syndrome.

J Med Cases 2021 Jul 13;12(7):284-287. Epub 2021 May 13.

Department of Internal Medicine, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Ehlers-Danlos syndrome is a group of rare genetic disorders of collagen characterized by skin hyperextensibility, joint hypermobility and tissue fragility. The authors describe a rare case of a 52-year-old woman that presented to the clinic with chronic joint pain and talipes equinovarum since childhood. Large eyes, sunken cheeks, thin nose and lobeless ears were noticed on clinical examination. Read More

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Skin wound healing promoted by novel curcumin-loaded micelle hydrogel.

Ann Transl Med 2021 Jul;9(14):1152

Nursing Department, People's Hospital of Luxian County, Luzhou, China.

Background: The development of biomaterials with the ability to promote skin wound healing is an important topic in the field of biomedical science. In this study, a topical curcumin (Cur) gel [Cur/hyaluronic acid (HA)] was prepared by combining curcumin-loaded PCL-b-PEG-b-PCL (PECE) nanomicelles (PCEC/Cur) and HA to effectively promote skin wound healing. Continuous drug release from PCEC/Cur can provide long-term protection and treatment of skin wounds. Read More

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Effects of Glycogen on Ceramide Production in Cultured Human Keratinocytes via Acid Sphingomyelinase Activation.

J Appl Glycosci (1999) 2021 11;68(2):41-46. Epub 2021 Jun 11.

1 Institute of Health Sciences, Ezaki Glico Co., Ltd.

Glycogen is a highly branched storage polysaccharide found mainly in the liver and the muscles. Glycogen is also present in the skin, but its functional role is poorly understood. Recently, it has been reported that glycogen plays an important role in intracellular signal transduction. Read More

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Pterosaurs.

Curr Biol 2021 Aug;31(16):R984-R989

School of GeoSciences, University of Edinburgh, Grant Institute, James Hutton Road, Edinburgh EH9 3FE, UK.

150 million years ago, an animal no bigger than a herring gull soared above shallow lagoons in what is now Bavaria. It had obscenely long fingers on each hand, which anchored thin wings of skin, and long toothy jaws, perfectly suited to snatching squids and fishes from the warm waters. Our animal was probably doing just that before its untimely death. Read More

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Surgical technique for the management of corneal perforation in brittle cornea.

Indian J Ophthalmol 2021 Sep;69(9):2521-2523

Department of Pediatric Ophthalmology, Narayana Nethralaya 2, Bangalore, Karnataka, India.

Brittle cornea syndrome is among the few special scenarios in ophthalmology that are a nightmare not only for the operating surgeon but also for the patient. Here, the thin and fragile corneas are unable to maintain the shape and structural integrity of the globe and are more prone to minor traumatic or spontaneous corneal perforations. Suturing a brittle cornea and closure of the corneal perforation in a brittle cornea are very challenging requiring the utmost care and special precautions. Read More

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September 2021