21,785 results match your criteria thickness volume

Effect of Isolated Obesity on Left Ventricular Function and Structure: A Single-Center Experience.

Cureus 2021 Mar 19;13(3):e13988. Epub 2021 Mar 19.

Cardiac Surgery, King Faisal Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Science, Jeddah, SAU.

Background and objectives Obesity can increase cardiac mass and affect cardiac performance independently from other risk factors. Several studies have identified an association in patients who already have comorbidities, however, few studies focused on obesity as an isolated risk factor. This study aimed to assess the associations between isolated obesity and heart morphological and functional characteristics. Read More

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Vitamin D Levels and Visual System Measurements in Progressive Multiple Sclerosis: A Cross-sectional Study.

Int J MS Care 2021 Mar-Apr;23(2):53-58. Epub 2020 Apr 28.

Background: Vitamin D deficiency is associated with increased disease activity in multiple sclerosis (MS), but its role in progressive MS has not been elucidated. The objective was to determine the correlation between vitamin D levels and visual parameters in primary progressive MS (PPMS) and secondary progressive MS (SPMS).

Methods: Serum 25-hydroxyvitamin D (25[OH]D) and 25-hydroxyvitamin D (25[OH]D) levels were obtained from the Secondary and Primary Progressive Ibudilast NeuroNEXT Trial in MS (SPRINT-MS). Read More

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Comparison of Macular Thickness Measurements Using Swept-Source and Spectral-Domain Optical Coherence Tomography in Healthy and Diabetic Subjects.

Curr Eye Res 2021 Apr 20:1-7. Epub 2021 Apr 20.

Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, People's Republic of China.

: To establish normative data for macular thickness in Chinese aged 30 to 80 years using the swept-source optical coherence tomography (SS-OCT) device.: The study included 290 normal eyes, 430 NDR eyes and 150 DR eyes of community residents aged 30 to 80 years in Guangzhou, China. Mean macular thicknesses in Early Treatment Diabetic Retinopathy Study (ETDRS) subfields, central point thicknesses (CPT), and macular volume was measured by SS-OCT (Triton DRI OCT, Topcon, Tokyo, Japan) and Spectral-Domain OCT (SD-OCT; Heidelberg Engineering, Heidelberg, Germany). Read More

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[Cortical morphological study in cerebral small vessel disease patients with subcortical ischemic depression].

Zhonghua Yi Xue Za Zhi 2021 Apr;101(15):1057-1063

Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.

To explore the characteristics of cortical morphology in cerebral small vessel disease (CSVD) patients with subcortical ischemic depression (SID) and its relationship with clinical symptoms. A total of 88 patients with CSVD in the First Affiliated Hospital of Anhui Medical University were enrolled from July 2017 to July 2020. The subjects were divided into CSVD-non depression group (CSVD-ND, =58) and SID group (=30) according to the geriatric depression scale (GDS). Read More

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A dynamic simulation framework for CT perfusion in stroke assessment built from first principles.

Med Phys 2021 Apr 20. Epub 2021 Apr 20.

Departments of Bioengineering and Radiology, Stanford University, Stanford, CA, 94305, USA.

Purpose: Physicians utilize cerebral perfusion maps (e.g., cerebral blood flow, cerebral blood volume, transit time) to prescribe the plan of care for stroke patients. Read More

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The Effects of Laparoscopic Sleeve Gastrectomy on Cardiac Diastolic Function, Aortic Elasticity, and Atrial Electromechanics Delay.

Obes Surg 2021 Apr 20. Epub 2021 Apr 20.

Department of Cardiology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.

Background: Obesity is a well-known risk factor for cardiovascular diseases. The aim of this study was to prospectively investigate the short-term effects of laparoscopic sleeve gastrectomy (LSG) on cardiac functions.

Methods: Forty-four morbidly obese patients who underwent LSG were included in the study. Read More

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Optic Nerve Parameters and Cognitive Function in the Northern Finland Birth Cohort Eye Study.

Ophthalmic Epidemiol 2021 Apr 20:1-9. Epub 2021 Apr 20.

Department of Ophthalmology, PEDEGO Research Unit and Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland.

Purpose: The optic nerve head (ONH) is a part of the brain that can be easily studied through the transparent medium of the eye. We explored the relationship between the properties of the optic nerve head, the retinal nerve fiber layer (RNFL) and cognitive function.

Methods: Participants of the Northern Finland Birth Cohort (NFBC) 1966 underwent an ophthalmic and cognitive assessment after randomization at age 46. Read More

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Wear resistance of crowns made from different CAM/CAD materials.

Dent Mater 2021 Apr 16. Epub 2021 Apr 16.

Department of Prosthodontics, Propaedeutics and Dental Materials, School of Dentistry, Christian-Albrechts University at Kiel, Germany. Electronic address:

Objectives: The aim of this laboratory study was to evaluate the wear resistance of crowns made from current computer-aided design and computer-aided manufacture (CAD/CAM) materials. In addition, the abrasion of the steatite antagonist against these materials was compared.

Methods: Identically shaped crowns of lithium disilicate, zirconia-reinforced lithium disilicate and a polymer-infiltrated ceramic network (PICN) were fabricated with an occlusal thickness of 1. Read More

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Diaphragmatic paralysis, respiratory function, and postoperative pain after interscalene brachial plexus block with a reduced dose of 10 ml levobupivacaine 0.25% versus a 20 ml dose in patients undergoing arthroscopic shoulder surgery: study protocol for the randomized controlled double-blind REDOLEV study.

Trials 2021 Apr 19;22(1):287. Epub 2021 Apr 19.

Department of Pneumology, Miguel Servet University Hospital, Zaragoza, Spain.

Background: Arthroscopic shoulder surgery causes severe postoperative pain. An interscalene brachial plexus block provides adequate analgesia, but unintended spread of the local anesthetic administered may result in a phrenic nerve block, usually associated with a nonnegligible incidence of acute hemidiaphragmatic paralysis. The main purpose of this trial will be to analyze the incidence of hemidiaphragmatic paralysis ensuing after interscalene brachial plexus block in patients undergoing arthroscopic shoulder surgery administered a standard volume (20 ml) vs. Read More

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Ozone-induced H O accumulation in field-grown aspen and birch is linked to foliar ultrastructure and peroxisomal activity.

New Phytol 2004 Mar;161(3):791-799

School of Forest Resources and Environmental Science, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.

•  Saplings of three aspen (Populus tremuloides) genotypes and seedlings of paper birch (Betula papyrifera) were exposed to elevated ozone (1.5× ambient) and 560 p.p. Read More

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Facile synthesis of ultrathin two-dimensional graphene-like CeO-TiO mesoporous nanosheet loaded with Ag nanoparticles for non-enzymatic electrochemical detection of superoxide anions in HepG2 cells.

Biosens Bioelectron 2021 Apr 10;184:113236. Epub 2021 Apr 10.

Shanghai Key Laboratory of Functional Materials Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, People's Republic of China; Research Center of Analysis and Test, East China University of Science and Technology, Shanghai, 200237, People's Republic of China. Electronic address:

Here we presented a new facile strategy to fabricate ultrathin two-dimensional (2D) metal oxide nanosheets, by using polydopamine-coated graphene (rGO@PDA) as a template under simply wet-chemical conditions. Based on the strategy, graphene-like CeO-TiO mesoporous nanosheet (MNS-CeO-TiO) was prepared and was loaded with dispersive Ag nanoparticles (AgNPs) to obtain effective electrocatalysts (denoted as Ag/MNS-CeO-TiO) for electrochemical detection of superoxide anion (O). Characterizations demonstrated that MNS-CeO-TiO exhibited ultrathin thickness, larger specific surface area, and pore volume in comparison with its bulk counterpart. Read More

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Dispositional Negative Emotionality in Childhood and Adolescence Predicts Structural Variation in the Amygdala and Caudal Anterior Cingulate During Early Adulthood: Theoretically and Empirically Based Tests.

Res Child Adolesc Psychopathol 2021 Apr 19. Epub 2021 Apr 19.

Vanderbilt University, Nashville, TN, USA.

Substantial evidence implicates the amygdala and related structures in the processing of negative emotions. Furthermore, neuroimaging evidence suggests that variations in amygdala volumes are related to trait-like individual differences in neuroticism/negative emotionality, although many questions remain about the nature of such associations. We conducted planned tests of the directional prediction that dispositional negative emotionality measured at 10-17 years using parent and youth ratings on the Child and Adolescent Dispositions Scale (CADS) would predict larger volumes of the amygdala in adulthood and conducted exploratory tests of associations with other regions implicated in emotion processing. Read More

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The role of surface stoichiometry in NO gas sensing using single and multiple nanobelts of tin oxide.

Phys Chem Chem Phys 2021 Apr 19. Epub 2021 Apr 19.

Department of Engineering, Physics and Mathematics, São Paulo State University (UNESP), Araraquara, 14800-900, Brazil.

Typically used semiconducting metal oxides (SMOs) consist of several varying factors that affect gas sensor response, including film thickness, grain size, and notably the grain-grain junctions within the active device volume, which complicates the analysis and optimisation of sensor response. In comparison, devices containing a single nanostructured element do not present grain-grain junctions, and therefore present an excellent platform to comprehend the correlation between nanostructure surface stoichiometry and sensor response to the depletion layer (Debye length, LD) variation after the analyte gas adsorption/chemisorption. In this work, nanofabricated devices containing SnO2 and Sn3O4 individual nanobelts of different thicknesses were used to estimate their LD after NO2 exposure. Read More

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Quantitative measurements of prostatic zones by MRI and their dependence on prostate size: possible clinical implications in prostate cancer.

Ther Adv Urol 2021 Jan-Dec;13:17562872211000852. Epub 2021 Mar 31.

Department of Urology, Texas Tech University Health Sciences Center - School of Medicine, 3601 4th Street, Lubbock, TX 79430-7260, USA.

Aim: Many studies support an inverse relationship between benign prostate hypertrophy (BPH) size and incidence of prostate cancer (PCa), but the causal link between these conditions is poorly understood. Recent studies suggest that a growing transition zone (TZ) in the prostate may induce pressure on the outer peripheral zone (PZ), leading to atrophy of the glandular tissue where PCa often originates, providing a possible explanation for this interaction. To further investigate this phenomenon, our pilot study uses magnetic resonance imaging (MRI) to examine quantitative zonal changes in a consecutive cohort of prostates. Read More

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Cortical Volume, Thickness, and Surface Area in the Motoric Cognitive Risk Syndrome.

J Alzheimers Dis 2021 Apr 13. Epub 2021 Apr 13.

Departments of Medicine Albert Einstein College of Medicine, Bronx, NY, USA.

Background: The motoric cognitive risk (MCR) syndrome is a pre-clinical stage of dementia characterized by slow gait and cognitive complaint. Yet, the brain substrates of MCR are not well established.

Objective: To examine cortical thickness, volume, and surface area associated with MCR in the MCR-Neuroimaging Consortium, which harmonizes image processing/analysis of multiple cohorts. Read More

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Hemodynamic and structural brain measures in high and low sedentary older adults.

J Cereb Blood Flow Metab 2021 Apr 17:271678X211009382. Epub 2021 Apr 17.

The Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.

Due to its cardiovascular effects sedentary behaviour might impact cerebrovascular function in the long term, affecting cerebrovascular regulatory mechanisms and perfusion levels. Consequently this could underly potential structural brain abnormalities associated with cognitive decline. We therefore assessed the association between sedentary behaviour and brain measures of cerebrovascular perfusion and structural abnormalities in community-dwelling older adults. Read More

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Remodelling of trabecular bone in human distal tibia: A model based on an in-vivo HR-pQCT study.

J Mech Behav Biomed Mater 2021 Apr 14;119:104506. Epub 2021 Apr 14.

Wolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough, UK.

An abnormal remodelling process of bones can lead to various bone disorders, such as osteoporosis, making them prone to fracture. Simulations of load-induced remodelling of trabecular bone were used to investigate its response to mechanical signal. However, the role of mechanostat in trabecular-bone remodelling has not yet been investigated in simulations underpinned by a longitudinal in-vivo study in humans. Read More

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Is the effect of atorvastatin 60 mg on stabilization of lipid-rich plaque equivalent to that of rosuvastatin 10 mg? A serial optical coherence tomography combined with intravascular ultrasound imaging.

Catheter Cardiovasc Interv 2021 Apr 17. Epub 2021 Apr 17.

Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China.

Objectives: This study aimed to compare the effect of atorvastatin 60 (AT60) mg to that of rosuvastatin 10 (RT10) mg on the morphological changes in lipid-rich plaques (LRPs) and plaque volume, using serial optical coherence tomography (OCT) and intravascular ultrasound imaging (IVUS).

Background: Intensive lipid lowering therapy by statin provides more clinical benefit compared to that of moderate lipid lowering therapy.

Methods: Fifty patients who underwent OCT and IVUS at baseline, 6, and 12 months were grouped by statin therapy into the AT60 mg (n = 27) and RT10 mg (n = 23) groups. Read More

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Multimodal brain predictors of current weight and weight gain in children enrolled in the ABCD study ®.

Dev Cogn Neurosci 2021 Mar 30;49:100948. Epub 2021 Mar 30.

Department of Psychiatry, University of Vermont, Burlington, VT, USA; Department of Psychological Science, University of Vermont, Burlington, VT, USA.

Multimodal neuroimaging assessments were utilized to identify generalizable brain correlates of current body mass index (BMI) and predictors of pathological weight gain (i.e., beyond normative development) one year later. Read More

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Etanercept prevents TNF-α mediated mandibular bone loss in FcγRIIb-/- lupus model.

PLoS One 2021 16;16(4):e0250215. Epub 2021 Apr 16.

Skeletal Disorders Research Unit, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.

Patients with systemic lupus erythematosus are at increased risk for alveolar bone loss due to periodontitis possibly as a result of a pathogenic immune response to oral bacteria and inflammation. The aim of the present study was to investigate whether an anti-TNF-α antagonist could prevent mandibular bone loss in the FcγRIIb-/- mouse model of lupus. Mice lacking FcγRIIb had decreased cancellous and cortical bone volume at 6 months of age. Read More

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Assessment of mean platelet volume and aortic intima media thickness in pediatric familial Mediterranean fever: as early markers of atherosclerosis.

Minerva Pediatr (Torino) 2021 Apr 16. Epub 2021 Apr 16.

Department of Pediatrics, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey.

Objective: Familial Mediterranean fever is the most common auto-inflammatory disease in childhood. The aim of present study is to assess whether familial Mediterranean fever increases the risk of premature atherosclerosis.

Materials And Methods: It is a case-control prospective study. Read More

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Effectiveness of placental volume measured by virtual organ computer-aided analysis in prediction of fetal hemoglobin Bart's disease in late first trimester.

J Clin Ultrasound 2021 Apr 16. Epub 2021 Apr 16.

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Objective: To evaluate the effectiveness of placental volume measured by virtual organ computer-aided analysis (VOCAL) at 12 to 14 weeks of gestation in predicting fetal hemoglobin (Hb) Bart's disease among pregnancies at risk.

Methods: This study involves 3-dimensional ultrasound (3D-US) volume datasets derived from pregnancies at risk of fetal Hb Bart's disease at 12 to 14 weeks of pregnancy. VOCAL technique was used to measure and calculate placental volume by the authors, who did not know the fetal diagnosis. Read More

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Longitudinal structural brain changes in Friedreich ataxia depend on disease severity: the IMAGE-FRDA study.

J Neurol 2021 Apr 15. Epub 2021 Apr 15.

School of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton Campus, Clayton, VIC, 3800, Australia.

Background: Friedreich ataxia is an inherited neurodegenerative disease, with cerebral and cerebellar pathology evident. Despite an increased understanding of its neuropathology, disease progression in this disease remains poorly understood. This study aimed to characterise longitudinal change in brain structure using a multi-modal approach across cerebral and cerebellar grey and white matter. Read More

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Robustness of radiomic features in CT images with different slice thickness, comparing liver tumour and muscle.

Sci Rep 2021 Apr 15;11(1):8262. Epub 2021 Apr 15.

Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK.

Radiomic image features are becoming a promising non-invasive method to obtain quantitative measurements for tumour classification and therapy response assessment in oncological research. However, despite its increasingly established application, there is a need for standardisation criteria and further validation of feature robustness with respect to imaging acquisition parameters. In this paper, the robustness of radiomic features extracted from computed tomography (CT) images is evaluated for liver tumour and muscle, comparing the values of the features in images reconstructed with two different slice thicknesses of 2. Read More

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No correlation between mean platelet volume and carotid artery thickness in patients with diabetes at intermediate or high risk for cardiovascular diseases.

Blood Coagul Fibrinolysis 2021 Apr 14. Epub 2021 Apr 14.

Department of Clinical Laboratory Department of Hematology, Chugoku Central Hospital, Fukuyama Department of Hematology, Okayama University Medical School, Okayama, Japan.

The number of patients with diabetes with a risk of cardiovascular diseases (CVDs) is increasing worldwide, leading to a higher demand for evaluating atherosclerosis. Recently, the mean platelet volume (MPV) available from complete blood count is gaining attention as a marker of underlying atherosclerotic lesions. In the current study, we examined whether MPV can predict carotid atherosclerosis in patients with diabetes at an intermediate or high risk for CVD. Read More

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A randomized, controlled clinical trial of autologous stromal vascular fraction cells transplantation to promote mechanical stretch-induced skin regeneration.

Stem Cell Res Ther 2021 Apr 15;12(1):243. Epub 2021 Apr 15.

Department of Plastic & Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizhaoju Road, Shanghai, 200011, People's Republic of China.

Background: The regeneration response of the skin to mechanical stretching in vivo has been explored in reconstructive surgery to repair large-scale deformities. The ability of the skin to regenerate limits the reconstructive outcome. Here, we propose an approach in which autologous stromal vascular fraction (SVF) cells and mechanical stretching are combined to overcome this limitation and promote skin regeneration. Read More

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Effect of citalopram on hippocampal volume in first-episode schizophrenia: Structural MRI results from the DECIFER trial.

Psychiatry Res Neuroimaging 2021 Apr 7;312:111286. Epub 2021 Apr 7.

Department of Psychiatry, NYU Langone Health, 1 Park Avenue, New York, NY 10016, United States of America; Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, United States of America. Electronic address:

Hippocampal volume loss is prominent in first episode schizophrenia (FES) and has been associated with poor clinical outcomes and with BDNF genotype; antidepressants are believed to reverse hippocampal volume loss via release of BDNF. In a 12-month, placebo-controlled add-on trial of the antidepressant, citalopram, during the maintenance phase of FES, negative symptoms were improved with citalopram. We now report results of structural brain imaging at baseline and 6 months in 63 FES patients (34 in citalopram group) from the trial to assess whether protection against hippocampal volume loss contributed to improved negative symptoms with citalopram. Read More

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Electrospun paclitaxel delivery system based on PGCL/PLGA in local therapy combined with brachytherapy.

Int J Pharm 2021 Apr 12:120596. Epub 2021 Apr 12.

Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 41-819 Zabrze, M. Curie-Sklodowskiej 34, Poland; Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Poland, Department of Biopharmacy, Jedności 8, Sosnowiec, Poland.

The local administration of different drugs in anticancer therapy continue to attract attention. Thus, the idea of local delivery of cytostatics from nonwoven-structured polyesters seems to be highly desirable. It could reduce systemic drug levels and provide high local concentration of the chemotherapeutics at the tumor site and contribute to enhance the efficiency of the anticancer therapy. Read More

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Separating the influences of late talking and dyslexia on brain structure.

J Abnorm Psychol 2021 Apr;130(3):286-296

Laboratory of Language Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences.

Being a late talker constitutes a risk factor for later neurodevelopmental disorders; however, its neurobiological basis remains unexplored. We aimed to determine the unique and mutual correlates of late talking and developmental dyslexia on brain structure and behavioral outcomes in a large sample of 8- to 10-year-old children in a between-groups design ( = 120). Brain structure was examined using voxel-based morphometry (to measure gray matter volume) and surface-based morphometry (to measure gray matter volume, cortical thickness, surface area, and curvature of the cortex). Read More

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Tibial Macrostructure and Microarchitecture Adaptations in Women During 44 Weeks of Arduous Military Training.

J Bone Miner Res 2021 Apr 15. Epub 2021 Apr 15.

Army Health and Performance Research, Army Headquarters, Andover, UK.

Bone adapts to unaccustomed, high-impact loading but loses mechanosensitivity quickly. Short periods of military training (≤12 weeks) increase the density and size of the tibia in women. The effect of longer periods of military training, where the incidence of stress fracture is high, on tibial macrostructure and microarchitecture in women is unknown. Read More

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