14,205 results match your criteria thermal injury

Long-tevrm outcomes of the MICOF keratoprosthesis surgery.

Ocul Surf 2021 Jun 9. Epub 2021 Jun 9.

Department of Ophthalmology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China. Electronic address:

Purpose: To evaluate long-term anatomical and functional outcomes of the MICOF keratoprosthesis to treat end-stage corneal blindness.

Design: Re trospective review of consecutive clinical case series.

Participants: Between October 2000 and October 2015, at the Department of Ophthalmology of Chinese PLA General Hospital (PLAGH), a total of 132 eyes of 131 patients had undergone a MICOF keratoprosthesis implantation. Read More

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Automated Medical Avatar Animation for Warfighter Mission Simulation.

J Trauma Acute Care Surg 2021 May 18. Epub 2021 May 18.

CFD Research Corporation, Huntsville, AL Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, Natick, MA Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ.

Background: Virtual representations of human internal anatomy are important for military applications such as protective equipment design, injury severity prediction, thermal analysis, and physiological simulations. High-fidelity volumetric models based on imaging data are typically in static postures, and difficult to utilize in simulations of realistic mission scenarios. This study aimed to investigate a hybrid approach to reposition medical avatars that preserves internal anatomy but allows rapid repositioning of full 3D meshes. Read More

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Significance of Contact Force on Esophageal Thermal Injury During Relative High-Power Short-Duration Ablation of Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2021 Jun 11:CIRCEP121009897. Epub 2021 Jun 11.

Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan. (T.K., K.A., N.H., M.N., S.Y., T.Y., T.M., A.Y., Y.T.).

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An Optimal Surgical Plane for Laparoscopic Functional Total Mesorectal Excision in Rectal Cancer.

J Gastrointest Surg 2021 Jun 9. Epub 2021 Jun 9.

Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, People's Republic of China.

Background: Intraoperative damage of pelvic autonomic nerves is the primary reason for postoperative sexual and urinary dysfunction after rectal cancer surgery,1,2 especially in patients with low rectal cancer. In the present study, we developed the nerve plane as a novel concept in rectal cancer surgery, which served as a landmark for better preservation of pelvic autonomic nerves in standardized total mesorectal excision (TME) surgery. The nerves never exist alone, and are always surrounded by tiny capillaries and adipose tissue, which are covered by a thin layer of membranous tissue, leading to a continuous plane, which we defined as the nerve plane. Read More

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Long-Term Results of Arthroscopic Capsular Shrinkage for Palmar Midcarpal Instability of the Wrist.

J Wrist Surg 2021 Jun 4;10(3):224-228. Epub 2021 Feb 4.

Department of Trauma & Orthopaedic Surgery, University Hospital Southampton, Southampton, Hampshire, United Kingdom.

 Midcarpal instability is a term for a collection of poorly understood conditions where the proximal row of the carpus is unstable. The most common type of midcarpal instability is palmar midcarpal instability (PMCI). Treatment for PMCI includes nonoperative proprioceptive retraining of the wrist, splints, and strengthening. Read More

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Long-term survival among elderly after burns compared with national mean remaining life expectancy.

Burns 2021 May 30. Epub 2021 May 30.

Department of Hand Surgery, Plastic Surgery and Burns in Linköping University, Sweden; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Introduction: As compared to younger adults, older people have a greater risk of domestic accidents, such as burns, and their prognosis is worsened by a diminished physiological ability to face a thermal trauma. The in-hospital mortality is adversely affected by old age and burn size, whereas less is known about the long-term-survival in elderly patients who survive a burn injury. The aim of this study was to investigate if elderly burn patients after discharge from a Swedish National Burn Centre have a shorter remaining life compared to the national population, by using calculated remaining Life Expectancy (rLE). Read More

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Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms.

Neural Regen Res 2022 Jan;17(1):185-193

Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA; Ralph H. Johnson VA Medical Center, Charleston, SC, USA.

Spinal cord injury (SCI) is associated with high production and excessive accumulation of pathological 4-hydroxy-trans-2-nonenal (4-HNE), a reactive aldehyde, formed by SCI-induced metabolic dysregulation of membrane lipids. Reactive aldehyde load causes redox alteration, neuroinflammation, neurodegeneration, pain-like behaviors, and locomotion deficits. Pharmacological scavenging of reactive aldehydes results in limited improved motor and sensory functions. Read More

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January 2022

Cannabis induced thermal epiglottitis in a pediatric patient.

Am J Emerg Med 2021 May 13;49:114-116. Epub 2021 May 13.

Department of Pediatrics, Section on Infectious Disease, United States of America. Electronic address:

Acute epiglottitis is an airway emergency presenting with edema and inflammation of the epiglottis and aryepiglottic folds [1]. Infectious and other non-infectious etiologies may cause significant airway injury presenting with similar clinical symptoms and radiographic findings [1]. While many causes of thermal epiglottitis have been described in the pediatric and young adult population, we describe an unusual case of an adolescent patient with cannabis induced thermal epiglottitis. Read More

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Hydra vulgaris shows stable responses to thermal stimulation despite large changes in the number of neurons.

iScience 2021 Jun 30;24(6):102490. Epub 2021 Apr 30.

Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.

Many animals that lose neural tissue to injury or disease can maintain behavioral repertoires by regenerating new neurons or reorganizing existing neural circuits. However, most neuroscience small model organisms lack this high degree of neural plasticity. We show that can maintain stable sensory-motor behaviors despite 2-fold changes in neuron count, due to naturally occurring size variation or surgical resection. Read More

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High voltage electrical injuries: outcomes & 1-year follow-up from a level 1 trauma centre.

Int J Burns Trauma 2021 15;11(2):115-122. Epub 2021 Apr 15.

Assistant Professor Trauma Surgery, Trauma Centre, AIIMS Rishikesh India.

Background: High voltage (>1000 V) electric injuries (HVEI) are rare, and dreaded due to profound myonecrosis and fatal arrhythmias. Trauma Centres are well equipped for acute and definitive treatment of injuries. Paucity of burn centres in Himalayan belt make trauma centres a prudent choice for management of HVEIs. Read More

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Freeze branding: a novel injurious mechanism for humans.

Int J Burns Trauma 2021 15;11(2):112-114. Epub 2021 Apr 15.

Department of Burn Surgery, United States Army Institute of Surgical Research Fort Sam Houston, TX, USA.

Freeze branding was first performed in 1966 to identify animals for agricultural purposes, and remains relevant today in veterinary medicine. In contrast, human branding for aesthetics, punishment, identification, and purported medicinal benefits is standardly performed through transfer of thermal energy via heat. Uniquely, this case report documents the first description of freeze branding as a mechanism of injury in humans resulting in a 0. Read More

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Glycopyrrolate does not ameliorate hypothermia associated bradycardia in healthy individuals: A randomized crossover trial.

Resuscitation 2021 Jun 1;164:79-83. Epub 2021 Jun 1.

University of Pittsburgh Department of Emergency Medicine, Pittsburgh, PA, United States.

Background: Hypothermia improves outcomes following ischemia-reperfusion injury. Shivering is common and can be mediated by agents such as dexmedetomidine. The combination of dexmedetomidine and hypothermia results in bradycardia. Read More

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Targeting gut dysbiosis as a means to enhance recovery from surgical brain injury.

Sarah Danehower

Surg Neurol Int 2021 3;12:210. Epub 2021 May 3.

Drexel University College of Medicine, Philadelphia, Pennsylvania, United States.

Background: Surgical brain injury (SBI) impacts roughly 800,000 people who undergo neurosurgical procedures each year. SBI is the result of unavoidable parenchymal damage, vessel disruption, and thermal injury that is an inherent part of all neurosurgical procedures. Clinically, SBI has been associated with postoperative seizures and long-term neurobehavioral deficits. Read More

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Hand sanitiser-fuelled fire performance and thermal injury: case report.

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

US Army Burn Center, US Army Institute of Surgical Research, Fort Sam Houston, Texas, USA

A 23-year-old man presented to our burn center after sustaining a 62.5% total body surface area burn during a fire performance, in which he applied alcohol-based hand sanitiser to his body and ignited it. The patient underwent 6 operations at this facility and was discharged after 41 days. Read More

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Biodegradable Stent with mTOR Inhibitor-Eluting Reduces Progression of Ureteral Stricture.

Int J Mol Sci 2021 May 26;22(11). Epub 2021 May 26.

Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 613016, Taiwan.

In this study, we investigated the effect of mTOR inhibitor (mTORi) drug-eluting biodegradable stent (DE stent), a putative restenosis-inhibiting device for coronary artery, on thermal-injury-related ureteral stricture in rabbits. In vitro evaluation confirmed the dose-dependent effect of mTORi, i.e. Read More

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Exploring Fatalities and Injuries in Construction by Considering Thermal Comfort Using Uncertainty and Relative Importance Analysis.

Int J Environ Res Public Health 2021 May 23;18(11). Epub 2021 May 23.

Department of Safety Engineering, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul 01811, Korea.

Fatal injury and accidents in the construction industry occur under the influence of outdoor weather conditions such as temperature, humidity and wind speed in all four seasons. Previous research in this area has focused on hot and cold weather conditions: hot weather causes heat rash, heat cramps and heat fainting, while cold weather causes fatigue, lumbago, and cold finger sensations. However, other weather conditions are also associated with, and cause, fatal injury and accidents. Read More

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Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Corneal Epithelial Repair In Vitro.

Cells 2021 May 19;10(5). Epub 2021 May 19.

Centre for Ocular Regeneration, Prof. Brien Holden Eye Research Centre, Sudhakar and Sreekanth Ravi Stem Cell Biology Laboratory, Hyderabad Eye Research Foundation, L.V. Prasad Eye Institute, Hyderabad 500034, India.

Corneal injuries are among the leading causes of blindness and vision impairment. Trauma, infectious keratitis, thermal and chemical (acids and alkali burn) injuries may lead to irreversible corneal scarring, neovascularization, conjunctivalization, and limbal stem cell deficiency. Bilateral blindness constitutes 12% of total global blindness and corneal transplantation remains a stand-alone treatment modality for the majority of end-stage corneal diseases. Read More

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N58A Exerts Analgesic Effect on Trigeminal Neuralgia by Regulating the MAPK Pathway and Tetrodotoxin-Resistant Sodium Channel.

Toxins (Basel) 2021 May 17;13(5). Epub 2021 May 17.

School of Life Sciences and Biopharmaceutical Science, Shenyang Pharmaceutical University, Shenyang 110016, China.

The primary studies have shown that scorpion analgesic peptide N58A has a significant effect on voltage-gated sodium channels (VGSCs) and plays an important role in neuropathic pain. The purpose of this study was to investigate the analgesic effect of N58A on trigeminal neuralgia (TN) and its possible mechanism. The results showed that N58A could significantly increase the threshold of mechanical pain and thermal pain and inhibit the spontaneous asymmetric scratching behavior of rats. Read More

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Mechanical and Thermal Properties of Hybrid Fibre-Reinforced Concrete Exposed to Recurrent High Temperature and Aviation Oil.

Materials (Basel) 2021 May 21;14(11). Epub 2021 May 21.

School of Physical, Environmental and Mathematical Sciences, UNSW, Canberra 2610, Australia.

Over the years, leaked fluids from aircraft have caused severe deterioration of airfield pavement. The combined effect of hot exhaust from the auxiliary power unit of military aircraft and spilt aviation oils have caused rapid pavement spalling. If the disintegrated concreted pieces caused by spalling are sucked into the jet engine, they may cause catastrophic damage to the aircraft engine or physical injury to maintenance crews. Read More

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MR-Guided Microwave Ablation in T1 Renal Cell Carcinoma: Initial Results in Clinical Routine.

Biomed Res Int 2021 13;2021:5537192. Epub 2021 May 13.

Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.

Objective: Percutaneous tumor ablation is usually performed using computed tomography (CT) or ultrasound (US) guidance, although reliable visualization of the target tumor could be challenging. Magnetic resonance- (MR-) guided ablation provides more reliable visualization of the target tumors and allows multiplanar imaging of the treatment process, making it the modality of choice, in particular if lesions are small.

Methods: From March 2016 to January 2018, 32 patients scheduled for percutaneous treatment of T1 RCC underwent MR-guided MWA. Read More

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Cast-Related Complications.

Orthop Clin North Am 2021 Jul;52(3):231-240

Department of Orthopedic Surgery, Akron Children's Hospital, 1 Perkins Way, Akron, OH 44308, USA. Electronic address:

Despite advances in surgical techniques and technology, casting remains an important treatment modality in the armamentarium of orthopedic surgery. Opportunities for skill development and complication management are a decreasing commodity for the surgeon in training. Appropriate indications for casting and technical expertise of cast application are key to complication avoidance. Read More

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Massive parietal defect with multiple enteroatmospheric fistulae after thermal injury abdomen in a metal industry accident: Case report of a rare survivor.

Trop Doct 2021 May 30:494755211019314. Epub 2021 May 30.

Assistant Professor, Division of Trauma Surgery, Department of Surgical Disciplines, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.

In industrial foundries, raw metal is heated almost up to its melting point and then passed through the rolling mill to mould it into a desired shape. Contact with hot machinery or the hot metal can cause severe deep burns. When such thermal injury involves the abdominal wall, complex bowel injury can occur, leading to life-threatening abdominal sepsis. Read More

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Efficacy of whole-body vibration on balance control, postural stability, and mobility after thermal burn injuries: A prospective randomized controlled trial.

Clin Rehabil 2021 May 30:2692155211020861. Epub 2021 May 30.

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

Objective: To investigate the additive effects of whole-body vibration (WBV) training to the traditional physical therapy program (TPTP) on balance control, postural stability, and mobility after thermal burn injuries.

Design: A single-blinded, randomized controlled study.

Setting: Outpatient physical therapy setting. Read More

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Long-term modulation of airway remodeling in severe asthma following bronchial thermoplasty.

Eur Respir J 2021 May 28. Epub 2021 May 28.

Departments of Physiology and Pharmacology.

Rationale: Bronchial thermoplasty is a mechanical therapeutic intervention that has been advocated as an effective treatment option for severe asthma. The mechanism is promoted as being related to the attenuation of airway smooth muscle which has been shown to occur in the short-term. However, long-term studies of the effects of bronchial thermoplasty on airway remodeling are few with only limited assessment of airway remodeling indices. Read More

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[A cross-sectional study on psychological needs of family members of critically ill inpatients in semi-closed wards and analysis of influence factors].

Zhonghua Shao Shang Za Zhi 2021 May;37(5):475-484

Department of Social Work, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

To analyze and discuss the psychological needs of family members of critically ill burn inpatients in semi-closed wards and their related influence factors. A cross-sectional survey was conducted among the 82 burn patients, who met the inclusion criteria and were admitted to the Department of Burns and Plastic Surgery of Ruijin Hospital of Shanghai Jiao Tong University School of Medicine from October 2018 to April 2019, and their family members. A general condition questionnaire of 15 indexes was applied to investigate the general data of burn patients and their family members including cause of burn, gender, age, total burn area, burn depth, burn severity, burn site, and type of medical insurance of patients, kinship with the patients, gender, age, experience of accompanying in intensive care isolation wards, occupation, education level, and monthly income of their family members. Read More

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Quercetin Alleviates Neuropathic Pain in the Rat CCI Model by Mediating AMPK/MAPK Pathway.

J Pain Res 2021 19;14:1289-1301. Epub 2021 May 19.

Department of Anesthesiology and Pharmacology, Xuzhou Medical University, Xuzhou, 221000, People's Republic of China.

Context: Quercetin (que) is one abundant flavonol with a variety of biological activities. Previous studies have shown quercetin can reduce neuropathic pain in rats with chronic constriction injury (CCI).

Objective: To evaluate the effects of quercetin on neuropathic pain in CCI model and explore its underlying mechanism in vivo. Read More

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Post-traumatic trigeminal neuropathy: correlation between objective and subjective assessments and a prediction model for neurosensory recovery.

J Headache Pain 2021 May 24;22(1):44. Epub 2021 May 24.

Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Kapucijnenvoer 33, 3000, Leuven, Belgium.

Background: Post-traumatic trigeminal neuropathy (PTN) can have a substantial effect on patient well-being. However, the relation between the neuropathic symptoms and their effect on psychosocial functioning remains a matter of debate. The purpose of this study was to evaluate the association between objective and subjective assessments of neurosensory function in PTN and predict neurosensory outcome using baseline measurements. Read More

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Delivery Room Interventions for Hypothermia in Preterm Neonates: A Systematic Review and Network Meta-analysis.

JAMA Pediatr 2021 May 24:e210775. Epub 2021 May 24.

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.

Importance: Prevention of hypothermia in the delivery room is a cost-effective, high-impact intervention to reduce neonatal mortality, especially in preterm neonates. Several interventions for preventing hypothermia in the delivery room exist, of which the most beneficial is currently unknown.

Objective: To identify the delivery room thermal care intervention that can best reduce neonatal hypothermia and improve clinical outcomes for preterm neonates born at 36 weeks' gestation or less. Read More

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Peritraumatic 17β-estradiol levels influence chronic posttraumatic pain outcomes.

Pain 2021 Mar 26. Epub 2021 Mar 26.

aInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States Departments of bAnesthesiology and cBiostatistics, University of North Carolina, Chapel Hill, NC, United States dForensic Nursing Program, Memorial Health System, Colorado Springs, CO, United States eDepartment of Emergency Medicine, Albert Einstein Medical Center, Philadelphia, PA, United States fJaycee Burn Center, University of North Carolina, Chapel Hill, NC, United States gForensic Nursing Program, Albuquerque SANE Collaborative, Albuquerque, NM, United States hDepartment of Emergency Medicine, Sinai Grace Hospital, Detroit, MI, United States iDepartment of Emergency Medicine, Detroit Receiving, Detroit, MI, United States jWashington Hospital Burn Center, Washington, DC, United States kDepartment of Surgery, University of South Florida, Tampa, FL, United States lDepartment of Emergency Medicine, University of North Carolina, Chapel Hill, NC, United States.

Biologic factors that predict risk for and mediate the development of common outcomes of trauma exposure such as chronic posttraumatic pain (CPTP) are poorly understood. In the current study, we examined whether peritraumatic circulating 17β-estradiol (E2) levels influence CPTP trajectories. 17β-estradiol levels were measured in plasma samples (n = 254) collected in the immediate aftermath of trauma exposure from 3 multiethnic longitudinal cohorts of men and women trauma survivors. Read More

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