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Dimensions of Creativity in Secondary School High-Ability Students.

Eur J Investig Health Psychol Educ 2021 Aug 24;11(3):953-961. Epub 2021 Aug 24.

Facultad de Educación, Universidad Internacional de la Rioja, 26006 Logroño, Spain.

The objective of this study was to analyze the dimensions of creativity in high-ability teenage students. Firstly, we reviewed the most relevant scientific contributions on creativity. Next, the dimensions of creativity in secondary school students who were previously identified as high-ability students were analyzed. Read More

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Highly Sensitive Uric Acid Detection Based on a Graphene Chemoresistor and Magnetic Beads.

Biosensors (Basel) 2021 Aug 29;11(9). Epub 2021 Aug 29.

Key Laboratory of Multifunctional Nanomaterials and Smart Systems, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215125, China.

In this study, we developed a low-cost, reusable, and highly sensitive analytical platform for the detection of the human metabolite uric acid (UA). This novel analysis platform combines the graphene chemoresistor detection technique with a magnetic bead (MB) system. The heterojunction (single-layer graphene and HfO thin-film material) of our graphene-based biosensor worked as a transducer to detect the pH change caused by the specific catalytic reaction between UA and uricase, and hence acquires a UA concentration. Read More

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Diagnosis of Endometriosis at Laparoscopy: A Validation Study Comparing Surgeon Visualization with Histologic Findings.

J Obstet Gynaecol Can 2021 Sep 22. Epub 2021 Sep 22.

Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON, Canada, K1H 8L6; Department of Obstetrics, Gynecology and Newborn Care, University of Ottawa, Rm 7236-3, 1967 Riverside Drive, Ottawa, ON, Canada, K1H 7W9; Minimally Invasive Gynecology, The Ottawa Hospital, 501 Smyth Rd, Ottawa, ON, Canada, K1H 8L6.

Objective: This study aimed to evaluate the validity of laparoscopic visualization for the diagnosis of endometriosis compared with histopathology.

Methods: We conducted a retrospective chart review at a tertiary care hospital in Canada for the period of April 1, 2016 to March 31, 2017. Of 1069 women, 96 were selected for having undergone laparoscopic visualization and concurrent histopathological biopsy for suspected endometriosis. Read More

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September 2021

Predicting if lung cancer will relapse-The role of neutrophil/lymphocyte ratio.

Hematol Oncol Stem Cell Ther 2021 Sep 20. Epub 2021 Sep 20.

Department of Hematology and Medical Oncology, Sinai Hospital of Baltimore, Baltimore, MD 21215, USA.

Objective/background: Baseline neutrophil/lymphocyte ratio (NLR), a surrogate marker for systemic inflammation and immunosuppression, is a well-studied prognostic marker in non-small cell lung cancer (NSCLC). This study tests if interim NLR is prognostic in NSCLC patients in remission.

Methods: This single-center, retrospective cohort study analyzed 131 NSCLC patients treated from 2010 to 2015 who achieved complete remission. Read More

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September 2021

VACuum INtubation (VACcIN) box restricts the exhaled air dispersion generated by simulated cough: description and simulation-based tests of an innovative aerosolization protective prototype.

J Clin Monit Comput 2021 Sep 25. Epub 2021 Sep 25.

Department of Anesthesiology and Pain Medicine of Maisonneuve-Rosemont Hospital, CIUSSS de l'Est de l'Ile de Montreal, University of Montreal, 5415 Boulevard de l'Assomption, Montreal, QC, H1T 2M4, Canada.

The COVID-19 pandemic has caused personal protective equipment shortages worldwide and required healthcare workers to develop novel ways of protecting themselves. Anesthesiologists in particular are exposed to increased risks of contamination when performing interventions such as airway manipulations. We developed and tested an aerosolization protective device which contains aerosols around the patient's airway and helps eliminate particles using negative pressure. Read More

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September 2021

An in-home rehabilitation program for the treatment of urinary incontinence symptoms in endometrial cancer survivors: a single-case experimental design study.

Int Urogynecol J 2021 Sep 25. Epub 2021 Sep 25.

Rehabilitation Department, Faculty of Medicine, Université Laval, Québec, Québec, Canada.

Introduction And Hypothesis: There is a high prevalence of urinary incontinence among endometrial cancer survivors. They are also known to present with pelvic floor muscle alterations. Evidence on the effects of conservative interventions for the management of UI is scarce. Read More

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September 2021

Maternal diet quality during pregnancy and child cognition and behavior in a US cohort.

Am J Clin Nutr 2021 Sep 25. Epub 2021 Sep 25.

Dorothy J and Gerald R Friedman School of Nutrition and Science Policy at Tufts University.

Background: Maternal intake of several nutrients during pregnancy is linked to offspring cognition. The relationship between maternal dietary patterns and offspring cognition is less established.

Objective: To examine associations of maternal diet quality during pregnancy with child cognition and behavior. Read More

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September 2021

Parental perceptions of genetic testing for children with autism spectrum disorders.

Am J Med Genet A 2021 Sep 25. Epub 2021 Sep 25.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.

Children with autism spectrum disorder (ASD) routinely undergo genetic testing (GT) to identify the causative genetic etiology of their ASD. As there are questions about the impact of GT beyond clinical diagnosis, we conducted a mixed methods study to assess the perceived benefits of GT by exploring factors that lead parents to pursue these tests and the benefits experienced. Respondents were part of a pretest or posttest group. Read More

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September 2021


Pediatr Pulmonol 2021 Sep 25. Epub 2021 Sep 25.

Division of Pediatric Pulmonology, Marmara University, School of Medicine, Istanbul, Turkey.

Background: Tracheostomy-related morbidity and mortality mainly occur due to decannulation, misplacement or obstruction of the tube. A standardized training can improve the skills and confidence of the caregivers in tracheostomy care (TC).

Objective: Our primary aim was to evaluate the efficiency of standardized training program on the knowledge and skills (changing-suctioning the tracheostomy tube) of the participants regarding TC. Read More

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September 2021

Detethering the Superficial Temporal Artery: Application to Tension Free STA-MCA Bypasses.

Clin Anat 2021 Sep 25. Epub 2021 Sep 25.

Department of Neurosurgery, Ochsner Health System, New Orleans, Louisiana, USA.

Background: Extracranial-intracranial bypass has been shown to be effective in the surgical treatment of moyamoya disease, complex aneurysms, and tumors that involve proximal vasculature in carefully selected patients. Branches of the superficial temporal artery (STA) are used commonly for the bypass surgery; however, an appropriate length of the donor vessel must be harvested to avoid failure secondary to anastomotic tension. The goal of this cadaveric study was to investigate quantitatively operative techniques that can increase the STA length available to facilitate tension-free STA-middle cerebral artery (MCA) bypass. Read More

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September 2021

How do primary care doctors compare to dentists in the referral of oral cancer?

Satish Kumar

Evid Based Dent 2021 Jan;22(3):94-95

Arizona School of Dentistry and Oral Health, A. T. Still University, Arizona, USA.

Data sources The authors searched electronic databases of Medline, Embase, Web of Science, Scopus, CINAHL and Google Scholar until May 2019. They also searched within the reference lists of studies, citation indexes and related articles from these electronic databases. Ongoing studies were searched in Research Registry, and Electronic Theses Online Service was used for searching theses. Read More

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January 2021

Clinical utility of genomic signatures in young breast cancer patients: a systematic review.

NPJ Breast Cancer 2020 Sep 25;6(1):46. Epub 2020 Sep 25.

Breast Cancer Center, Hospital Zambrano Hellion, Tecnologico de Monterrey, San Pedro Garza Garcia, Mexico.

Risk stratification by genomic signatures has been shown to improve prognostication and guide treatment decisions among patients with hormone-sensitive breast cancer. However, their role in young women has not been fully elucidated. In this review, a systematic search was conducted for published articles and abstracts from major congresses that evaluated the use of genomic signatures in young breast cancer patients. Read More

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September 2020

A longitudinal sampling study of transcriptomic and epigenetic profiles in patients with thrombocytopenia syndrome.

Nat Commun 2021 Sep 24;12(1):5629. Epub 2021 Sep 24.

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, China.

Severe fever with thrombocytopenia syndrome (SFTS) is a novel tick-borne infectious disease caused by a new type of SFTS virus (SFTSV). Here, a longitudinal sampling study is conducted to explore the differences in transcript levels after SFTSV infection, and to characterize the transcriptomic and epigenetic profiles of hospitalized patients. The results reveal significant changes in the mRNA expression of certain genes from onset to recovery. Read More

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September 2021

Individuals' preference for financial over social incentives for medication adherence.

J Am Pharm Assoc (2003) 2021 Sep 8. Epub 2021 Sep 8.

Background: Patients with chronic conditions continue to face financial and system-related barriers to medication adherence. Pharmacy, provider, and payer-based financial and social incentive-based interventions may reduce these barriers and improve adherence. However, it is unclear how patient demographics and clinical characteristics influence the type of incentives preferred by patients. Read More

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September 2021

Acceptance and perceived value of non-invasive malaria diagnostic tests in malaria-endemic countries.

Malar J 2021 Sep 24;20(1):379. Epub 2021 Sep 24.

FIND, Geneva, Switzerland.

Background: The diagnosis of malaria, using microscopy or rapid diagnostic tests (RDTs), requires the collection of capillary blood. This procedure is relatively simple to perform but invasive and poses potential risks to patients and health workers, arising from the manipulation of potentially infectious bodily fluids. Less or non-invasive diagnostic tests, based on urine, saliva or requiring no sampling, have the potential to generate less discomfort for the patient and to offer simpler and less risky testing procedures that could be safely performed by untrained staff or even self-performed. Read More

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September 2021

Tiered Guidelines in a Pediatric Orthopaedic Practice Reduce Opioids Prescribed at Discharge.

J Pediatr Orthop 2021 Sep 27. Epub 2021 Sep 27.

Department of Orthopedic Surgery, Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.

Background: Data regarding opioid prescribing patterns following pediatric orthopaedic procedures is limited. The aim of this work was to evaluate the effects of tiered guidelines for discharge opioid prescriptions following common pediatric orthopaedic procedures.

Methods: Quality improvement project conducted at a single academic institution. Read More

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September 2021

Simulation in disaster nursing education: A scoping review.

Nurse Educ Today 2021 Aug 30;107:105119. Epub 2021 Aug 30.

School Of Health Sciences, Wuhan University, Located on No. 115 Donghu Road, Wuhan, Hubei province 430071, China. Electronic address:

Objectives: Disasters are gradually increasing in type and frequency throughout the globe. Simulation is being used in disaster nursing teaching and training. The aim of this scoping review was to systematically map the extent and application of simulation in disaster nursing education. Read More

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Birth Satisfaction During the Early Months of the COVID-19 Pandemic in the United States.

MCN Am J Matern Child Nurs 2021 Sep 23. Epub 2021 Sep 23.

Elizabeth Mollard, Assistant Professor, University of Nebraska Medical Center, College of Nursing - Lincoln Division, Lincoln, NE. Dr. Mollard can be reached via email at Kevin Kupzyk, Assistant Professor, University of Nebraska Medical Center, College of Nursing - Omaha Division, 985330 Nebraska Medical Center, Omaha, NE.

Abstract: Purpose: The purpose of this study was to describe birth satisfaction in women who gave birth in U.S. hospitals during the earliest months of the COVID-19 pandemic (March-July 2020). Read More

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September 2021

Continued Upward Trend in Non-Tuberculous Mycobacteria Isolation over 13 Years in a Tertiary Care Hospital in Korea.

Yonsei Med J 2021 Oct;62(10):903-910

Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.

Purpose: Despite decreased prevalence of tuberculosis, the incidence of the diseases associated with nontuberculous mycobacteria (NTM) has been increasing in South Korea and around the world. The present retrospective study was conducted to determine longitudinal changes in the epidemiology and distribution of NTM over 13 years at a tertiary care hospital in Korea.

Materials And Methods: We retrospectively analyzed data on species over 13 years (January 2007 to December 2019) by utilizing the laboratory information system. Read More

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October 2021

Less Exposure for Health Care Workers, More Comfort for Patients During COVID-19 Swab Testing.

Workplace Health Saf 2021 Sep 24:21650799211045309. Epub 2021 Sep 24.

University of Health Science Antalya Training and Research Hospital.

Background: Nasopharyngeal (NP) and oropharyngeal (OP) swab sampling for coronavirus disease 2019 (COVID-19) diagnosis may lead to droplet and/or airborne particle transmission and increase the exposure risk for health care workers (HCWs). However, there is limited evidence for effective methods to reduce occupational exposure from NP and OP swab sampling. This study aimed to reduce droplet-forming responses (DFRs) and the related exposure risk of NP and OP swab sampling by administering 10% lidocaine spray (LS) to the NP and OP areas prior to conducting swab tests. Read More

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September 2021

Factors Influencing the Selection of Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention in Patients With Non-Valvular Atrial Fibrillation.

J Cardiovasc Pharmacol Ther 2021 Sep 24:10742484211049919. Epub 2021 Sep 24.

College of Pharmacy, Pusan National University, Busan, Republic of Korea.

Background: Major atrial fibrillation (AF) guidelines recommend non-vitamin K antagonist oral anticoagulants (NOACs) over warfarin, except in rare clinical circumstances based on 4 randomized controlled trials comparing each NOAC with warfarin. We aimed to investigate the current NOAC prescription behaviors in alignment with the recent clinical evidence available.

Method: We conducted a cross-sectional analysis of NOAC-using patients with non-valvular atrial fibrillation (NVAF) who were aged ≥65 years on the index date (July 1, 2018) based on nationwide claims data. Read More

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September 2021

Prevalence of spp. in symptomatic BaAka Pygmies inhabiting the rural Dzanga Sangha region of the Central African Republic.

Ann Agric Environ Med 2021 Sep 7;28(3):483-490. Epub 2021 Sep 7.

Department of Tropical Parasitology, Institute of Maritime and Tropical Medicine, Medical University, Gdańsk, Poland.

Introduction: Malaria remains a diagnostic and therapeutic challenge in many endemic regions of sub-Saharan Africa. It is one of the most important causes of morbidity and mortality, especially in children <5 years. is responsible for the majority of severe malaria cases in sub-Saharan Africa, but is not the exclusive one. Read More

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September 2021

Evaluation of the Sysmex XN-31 automated analyser for blood donor malaria screening at Malawi Blood Transfusion Services.

Vox Sang 2021 Sep 23. Epub 2021 Sep 23.

Sysmex Europe, Norderstedt, Germany.

Background And Objectives: Balancing blood supply safety and sufficiency is challenging in malaria-endemic countries where the risk of transfusion-transmitted malaria (TTM) is ever-present. In support of reducing this risk, our study aimed at evaluating the performance of the Sysmex XN-31 analyser in blood donor malaria screening, as compared with current practice in Malawi.

Materials And Methods: This prospective observational study was conducted on remnant venous donor blood samples collected at Malawi Blood Transfusion Service donation sites countrywide for routine blood-borne pathogen screening. Read More

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September 2021

Design of a Wearable Haptic Device for Hand Palm Cutaneous Feedback.

Front Robot AI 2021 7;8:706627. Epub 2021 Sep 7.

Department of Information Engineering and Mathematics, University of Siena, Siena, Italy.

This study describes the main design and prototyping steps of a novel haptic device for cutaneous stimulus of a hand palm. This part of the hand is fundamental in several grasping and manipulation tasks, but is still less exploited in haptics applications than other parts of the hand, as for instance the fingertips. The proposed device has a parallel tendon-based mechanical structure and is actuated by three motors positioned on the hand's back. Read More

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September 2021

An Corrosion Model for Biomedical Applications for Coupling With Biocompatibility Tests for Estimation of Long-Term Effects.

Front Bioeng Biotechnol 2021 7;9:718026. Epub 2021 Sep 7.

SPARTHA Medical, Strasbourg, France.

The release of metal particles and ions due to wear and corrosion is one of the main underlying reasons for the long-term complications of implantable metallic implants. The rather short-term focus of the established biocompatibility tests cannot take into account such effects. Corrosion behavior of metallic implants mostly investigated in body-like environments for long time periods and their coupling with long-term experiments are not practical. Read More

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September 2021

National Resident Matching Program Performance Among US MD and DO Seniors in the Early Single Accreditation Graduate Medical Education Era.

Cureus 2021 Aug 20;13(8):e17319. Epub 2021 Aug 20.

Pathology, Kansas City University College of Osteopathic Medicine, Kansas City, USA.

Introduction: As of the 2020 National Resident Matching Program (NRMP), nearly all applicants are evaluated together for graduate medical education (GME) candidacy. We set out to characterize US MD and DO Senior residency match performance in the single-accreditation GME era.

Methods: A retrospective study was conducted in 2021 utilizing data collected from the 2018 and 2020 NRMP Charting Outcomes in the Match publications aggregated and subdivided into three groups based on competitiveness: low (LC), moderate (MC), and high (HC). Read More

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Antibacterial activity of endosymbiotic bacterial compound from sp. earthworms inhibit the growth of Typhi and : and approach.

Iran J Microbiol 2021 Aug;13(4):537-543

Department of Biology, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Makassar, Indonesia.

Background And Objectives: Earthworms coexist with various pathogenic microorganisms; thus, their immunity mechanisms have developed through a long process of adaptation, including through endogenous bacterial symbionts. This study aims to identify earthworm endosymbiont bacteria compounds and their antibacterial activity through an approach supported by an approach.

Materials And Methods: This research was conducted using the inhibition test through agar diffusion and the test using molecular docking applications, namely, PyRx and Way2Drugs Prediction of Activity Spectra for Substances (PASS). Read More

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Interaction between Chitosan and Chloroquine against and Using In-Vivo and In-Vitro Tests.

Iran J Parasitol 2021 Apr-Jun;16(2):261-269

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: The use of antimalarial drugs with number of compounds in combination form may potentiate each other's activity.

Methods: This study was conducted in the School of Public Health, Tehran University of Medical Sciences, Tehran, Iran in 2018. It was based on two methods including in vivo and in vitro tests with aim of considering interaction between chitosan and chloroquine against and parasites using different ratios of the agents with ED50 and IC50 baselines. Read More

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A Novel Chimeric Antigen as a Vaccine Candidate against : In silico Analysis.

Iran J Parasitol 2021 Apr-Jun;16(2):186-198

Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Background: is a mandatory intracellular pathogen and causing neglected disease. Hence, protection against leishmaniasis by a development vaccine is an important subject. This study aimed to design a poly-epitope vaccine for cutaneous leishmaniasis. Read More

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