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Synergistic effects of plant growth promoting rhizobacteria and silicon dioxide nano-particles for amelioration of drought stress in wheat.

Plant Physiol Biochem 2021 Jun 4;166:160-176. Epub 2021 Jun 4.

Department of Botany, S.P. College, Srinagar, Jammu, and Kashmir, India.

Drought tolerant plant growth-promoting rhizobacteria (PGPR) can confer drought tolerance in plants, when inoculated, and this effect can be more pronounced by their combined application with silicon oxide nanoparticles (SiO NPs). In this research, drought-tolerant and plant growth-promoting rhizobacterial strains were isolated from the rhizospheric soil of wheat plants growing in the arid region of Pakistan. Out of 30 isolated strains, three rhizobacterial strains were selected based on their drought tolerance, higher phytohormones (indole acetic acid (IAA), abscisic acid (ABA), and cytokinin (CK), and osmolyte (proline and sugar) production ability. Read More

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Remediation of textile industry organic dye waste by photocatalysis using eggshell impregnated ZnO/CuO nanocomposite.

Authors:
Mekdes Gerawork

Water Sci Technol 2021 Jun;83(11):2753-2761

Department of Chemistry, College of Natural and Computational Science, Debre Berhan University, P.O. Box 445 Debre Berhan, Ethiopia E-mail:

Heterogeneous photocatalysis using nanocomposites is of great research interest in the treatment of industrial wastewater. The impregnated photocatalyst was produced by liquid state reaction of ZnO/CuO nanocomposite with extracted eggshells. The structure, functional group, metal composition, bandgap, and photocatalytic activity of the nanocomposites were characterized by using X-ray diffraction, Fourier-transform infrared spectroscopy, atomic absorption spectrometry, and UV-Vis spectroscopy, respectively, in the absence and presence of eggshells. Read More

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Phenotypic and genotypic characterization of mcr-1-positive multidrug-resistant Escherichia coli ST93, ST117, ST156, ST10, and ST744 isolated from poultry in Poland.

Braz J Microbiol 2021 Jun 10. Epub 2021 Jun 10.

The Faculty of Veterinary Medicine, Department of Epizootiology and Clinic of Birds and Exotic Animals, Wrocław University of Environmental and Life Sciences, Pl. Grunwaldzki 45, 50-366, Wrocław, Poland.

Background: A plasmid-mediated mechanism of bacterial resistance to polymyxin is a serious threat to public health worldwide. The present study aimed to determine the occurrence of plasmid-mediated colistin resistance genes and to conduct the molecular characterization of mcr-positive Escherichia coli strains isolated from Polish poultry.

Methods: In this study, 318 E. Read More

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Antigenic and Molecular Characterization of Virulent Newcastle Disease Viruses Circulating in Ethiopia Between 1976 and 2008.

Vet Med (Auckl) 2021 4;12:129-140. Epub 2021 Jun 4.

Institute of Infectology, Friedrich-Loeffler-Institut, Greifswald, Germany.

Introduction: Newcastle disease virus (NDV) cultures held in the isolate collections in Ethiopia between 1976 and 2008 were not characterized using biological and molecular techniques. The already characterized NDV isolates belonged to genotype VI but the genetic nature of previously collected isolates, which could shade light on the history of introduction into the country and their evolutionary relationships, were not established.

Methods: A total of 14 NDVs (11 obtained from outbreak cases in chickens and three commercial vaccinal strains used in the country) were inoculated into specific pathogen free (SPF) embryonated chicken eggs (ECE). Read More

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Genetic Analysis of a Horizontal Resistance Locus in .

Front Plant Sci 2021 25;12:663868. Epub 2021 May 25.

Department of Plant Science, University of Manitoba, Winnipeg, MB, Canada.

causes blackleg disease in . The blackleg disease is mainly controlled by resistance genes in . Previous studies have shown that the blackleg resistant locus that conferred horizontal resistance under field conditions, is located on chromosome A10 of . Read More

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PIGG variant pathogenicity assessment reveals characteristic features within 19 families.

Genet Med 2021 Jun 10. Epub 2021 Jun 10.

Sydney Children's Hospital, Centre for Clinical Genetics, Sydney Children's Hospital, High St, Randwick, UK.

Purpose: Phosphatidylinositol Glycan Anchor Biosynthesis, class G (PIGG) is an ethanolamine phosphate transferase catalyzing the modification of glycosylphosphatidylinositol (GPI). GPI serves as an anchor on the cell membrane for surface proteins called GPI-anchored proteins (GPI-APs). Pathogenic variants in genes involved in the biosynthesis of GPI cause inherited GPI deficiency (IGD), which still needs to be further characterized. Read More

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Insulin resistance is linked to a specific profile of immune activation in human subjects.

Sci Rep 2021 Jun 10;11(1):12314. Epub 2021 Jun 10.

Immunology Department, Nîmes University Hospital, Place du Pr Debré, 30029, Nîmes, France.

We tested the hypothesis that a particular immune activation profile might be correlated with insulin resistance in a general population. By measuring 43 markers of immune, endothelial, and coagulation activation, we have previously shown that five different immune activation profiles may be distinguished in 150 volunteers. One of these profiles, Profile 2, characterized by CD4+ T cell senescence, inflammation, monocyte, B cell, and endothelial activation, presented elevated insulinemia, glycemia, triglyceridemia, and γ-glutamyl transferase, a marker of liver injury, in comparison with other profiles. Read More

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Behavioral Therapy for Tremor or Dystonia Affecting Voice in Speakers with Hyperkinetic Dysarthria: A Systematic Review.

J Voice 2021 Jun 7. Epub 2021 Jun 7.

Department of Physical Medicine & Rehabilitation, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Think + Speak Lab, Shirley Ryan AbilityLab, Chicago, Illinois.

Introduction: Hyperkinetic dysarthria is characterized by atypical involuntary movements within the speech mechanism that may affect the respiratory, laryngeal, pharyngeal-oral, or velopharyngeal-nasal subsystems and may alter speech production. Although articulatory impairments are commonly considered in hyperkinetic dysarthria, speakers with hyperkinetic dysarthria may also present with changes in voice quality, pitch, and loudness. In approximately 70% of speakers with hyperkinetic dysarthria, these voice alterations are associated with tremor or dystonia. Read More

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Diacylglycerols ions as novel marker indicators for the classification of edible oils using ultrahigh resolution mass spectrometry.

Food Res Int 2021 Jul 19;145:110422. Epub 2021 May 19.

Key Laboratory of Agro-food Safety and Quality of Ministry of Agriculture and Rural Affairs, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

Diacylglycerols (DAGs) ions, instead of triacylglycerols (TAGs) ions, were established as marker indicators for an improved classification of edible oils using ultrahigh resolution mass spectrometry (UHRMS). DAGs ions can be used not only to identify triacylglycerols (TAGs) and their embedded fatty acids (FAs), but also to distinguish positional isomers of TAGs. In this work, DAGs ions were determined in edible oils by direct infusion atmospheric pressure chemical ionization-ultrahigh resolution mass spectrometry (APCI-UHRMS), where the ultrahigh resolving power up to 500,000 FWHM (full width at half maximum) can provide accurate molecular compositions and detailed fingerprints MS spectra in a minute. Read More

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Lactobacillus rhamnosus GG orchestrates an anti-tumor immune response.

Cell Mol Gastroenterol Hepatol 2021 Jun 7. Epub 2021 Jun 7.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University School of Medicine, Atlanta GA, 30322; Emory Microbiome Research Center, Emory University School of Medicine, Atlanta GA, 30322. Electronic address:

Background And Aims: In colorectal cancer, about 95% of patients are refractory to immunotherapy due to low anti-tumor immune responses. Therefore, these is an exigent need to develop treatments that increase anti-tumor immune responses and decrease tumor burden to enhance immunotherapy.

Methods: The gut microbiome has been described as a master modulator of immune responses. Read More

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Identification of neolignans with PCSK9 downregulatory and LDLR upregulatory activities from Penthorum chinense and the potential in cholesterol uptake by transcriptional regulation of LDLR via SREBP2.

J Ethnopharmacol 2021 Jun 7:114265. Epub 2021 Jun 7.

College of Pharmacy and Research Institute of Pharmaceutical Sciences,Seoul National University, 1, Gwanak-ro, Gwanak-gu,Seoul 08826,Republic of Korea. Electronic address:

Ethnopharmacological Relevance: Penthorum chinense has been used in East Asia for the treatment of cholecystitis, infectious hepatitis, jaundice and to treat liver problems. Recent evidences provided the potential for the clinical use of P. chinense in the treatment of metabolic disease. Read More

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The inhibition of inducible nitric oxide production in lipopolysaccharide-stimulated rat macrophages and in silico studies by flavonoids from Iris spuria L. rhizomes.

J Ethnopharmacol 2021 Jun 7:114311. Epub 2021 Jun 7.

Pharmacognosy Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt; Pharmacognosy Department, College of Pharmacy, Taif University, Taif, Saudi Arabia.

Ethnopharmacological Relevance: Iris is the largest genus in the family Iridaceae. Iris plants are distributed in tropical regions of the world. They are used as ornamentals and traditionally used to treat a variety of ailments. Read More

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The Notch receptor-ligand Delta is involved in the immune response of Penaeus vannamei.

Dev Comp Immunol 2021 Jun 7:104147. Epub 2021 Jun 7.

Department of Biology and Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, 515063, China; STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou, 515063, China. Electronic address:

In the Notch signaling pathway in vertebrates and invertebrates, the ligand Delta plays crucial roles in cell proliferation, differentiation, and immunity. Although the Notch signaling pathway has recently been implicated in the immune defense of Penaeus vannamei, the association of Delta with this immune response remains unclear. Here, we cloned and characterized the Delta homolog in P. Read More

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Stress and corticotropin releasing factor (CRF) promote necrotizing enterocolitis in a formula-fed neonatal rat model.

PLoS One 2021 10;16(6):e0246412. Epub 2021 Jun 10.

Department of Obstetrics and Gynecology, Center for Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America.

The etiology of necrotizing enterocolitis (NEC) is not known. Alterations in gut microbiome, mucosal barrier function, immune cell activation, and blood flow are characterized events in its development, with stress as a contributing factor. The hormone corticotropin-releasing factor (CRF) is a key mediator of stress responses and influences these aforementioned processes. Read More

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Biodegradable Polymers and Gold Nanoparticle-Decorated Skin Substitutes: Synthesis, Characterization, and In Vitro Biological Activities.

Appl Biochem Biotechnol 2021 Jun 10. Epub 2021 Jun 10.

Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women, 641043, Coimbatore, India.

Skin substitutes are a restorative material used to treat many skin injuries by replacing or masking the wound. It is also capable of producing an original skin type. In this study, gold nanoparticle-aided skin substitutes were prepared using biodegradable materials (chitosan, sodium alginate, and gelatin) under the magnetic stirring method. Read More

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Synthesis, Molecular Docking, and Biological Evaluation of Some Novel 2-(5-Substituted 1,3,4-oxadiazole-2-yl)-1,3-benzothiazole Derivatives as Anticonvulsant Agents.

Cent Nerv Syst Agents Med Chem 2021 Jun 7. Epub 2021 Jun 7.

Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi, 110062, India.

Background: Benzothiazole is an organosulfur heterocyclic compound that has a considerable place in drug discovery due to significant pharmacological actions.

Objective: The main objective of the present study was to synthesize some novel 2-(5-substituted 1,3,4-oxadiazole-2-yl)-1,3-benzothiazole derivatives and evaluate them for their anticonvulsant activity using in silico and in vivo methods.

Method: A set of sixteen 2-(5-substituted 1, 3, 4-oxadiazole-2-yl)-1, 3-benzothiazole derivatives were prepared using multi-step reactions starting from o-amino-thiophenol and characterized by suitable spectral techniques. Read More

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Otilonium Bromide treatment prevents nitrergic functional and morphological changes caused by chronic stress in the distal colon of a rat IBS model.

J Cell Mol Med 2021 Jun 9. Epub 2021 Jun 9.

Research Unit of Histology and Embryology, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Irritable bowel syndrome (IBS) is a highly prevalent gastrointestinal disorder characterized by periods of remission and exacerbation. Among the risk factors to develop IBS, psychosocial stress is widely acknowledged. The water avoidance stress repeatedly applied (rWAS) is considered effective to study IBS etio-pathogenesis. Read More

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Disk Diffusion Susceptibility Testing for the Rapid Detection of Fluconazole Resistance in Isolates.

Ann Lab Med 2021 Nov;41(6):559-567

Department of Laboratory Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, Korea.

Background: Given the increased fluconazole resistance (FR) among isolates, we assessed the suitability of disk diffusion susceptibility testing (DDT) for the early detection of FR using well-characterized isolates.

Methods: In total, 188 isolates, including 66 (seven Erg11 mutants), 69 (33 Pdr1 mutants), 29 (15 Erg11 mutants), and 24 (eight Erg11 mutants) isolates, were tested in this study. FR was assessed using DDT according to the standard CLSI M44-ED3 method, except that two cell suspensions, McFarland 0. Read More

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November 2021

Sleep and neighborhood socioeconomic status: a micro longitudinal study of chronic low-back pain and pain-free individuals.

J Behav Med 2021 Jun 9. Epub 2021 Jun 9.

Department of Psychology, University of Alabama at Birmingham, 1300 University Boulevard, Campbell Hall, Room 237B, Birmingham, AL, 35294, USA.

Individuals with chronic low back pain (cLBP) frequently report sleep disturbances. Living in a neighborhood characterized by low-socioeconomic status (SES) is associated with a variety of negative health outcomes, including poor sleep. Whether low-neighborhood SES exacerbates sleep disturbances of people with cLBP, relative to pain-free individuals, has not previously been observed. Read More

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Resting-state functional connectivity in patients with a complex PTSD or complex dissociative disorder before and after inpatient trauma treatment.

Brain Behav 2021 Jun 9:e02200. Epub 2021 Jun 9.

Department of Psychiatry, Psychotherapy, and Psychosomatics, University Hospitals and University of Halle (Saale), Halle, Germany.

Introduction: Recent research suggests that traumatized patients are characterized by disrupted resting-state functional connectivity. We examined whether neural networks involved in resting-state change over the course of a phase-oriented inpatient treatment for complex traumatized and dissociative disorder patients. We also investigated associations between these network alterations and clinical symptoms and emotion regulation skills. Read More

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Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil.

Rev Soc Bras Med Trop 2021 2;54:e00402021. Epub 2021 Jun 2.

Fundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brasil.

Introduction: We aimed to describe the sociodemographic, epidemiological, and clinical characteristics of patients with chronic Chagas disease (CD) at an infectious disease referral center. Changes in patient profiles over time were also evaluated.

Methods: This retrospective study included patients with CD from November 1986-December 2019. Read More

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Highly Effective Pd/MgO/γ-AlO Catalysts for CO Oxidative Coupling to Dimethyl Oxalate: The Effect of MgO Coating on γ-AlO.

ACS Appl Mater Interfaces 2021 Jun 9. Epub 2021 Jun 9.

Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

The support of MgO/γ-AlO was initially prepared by a multiple impregnation method and Pd was placed on the surface of the MgO/γ-AlO support via incipient wetness impregnation. Pd/MgO/γ-AlO (Pd/MAO) catalysts were systematically characterized by X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), CO-temperature-programmed desorption (TPD), transmission electron microscopy (TEM), CO-Fourier transform infrared (CO-FTIR), and X-ray photoelectron spectroscopy (XPS) and tested in the CO oxidative coupling to dimethyl oxalate (DMO) reaction. Compared to Pd/γ-AlO, the catalytic activities of the Pd/MAO catalysts improved significantly. Read More

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Association between ABO and Duffy blood types and circulating chemokines and cytokines.

Genes Immun 2021 Jun 8. Epub 2021 Jun 8.

Infections and Immunoepidemiology Branch, DCEG, NCI, Bethesda, MD, USA.

Blood group antigens are inherited traits that may play a role in immune and inflammatory processes. We investigated associations between blood groups and circulating inflammation-related molecules in 3537 non-Hispanic white participants selected from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Whole-genome scans were used to infer blood types for 12 common antigen systems based on well-characterized single-nucleotide polymorphisms. Read More

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is essential for neuropeptide secretion in neurons.

J Neurosci 2021 Jun 7. Epub 2021 Jun 7.

Section Functional genomics, Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), UMC Amsterdam, The Netherlands

Neuropeptide secretion from dense-core vesicles (DCVs) controls many brain functions. Several components of the DCV exocytosis machinery have recently been identified, but the participation of a SEC1/MUNC18 (SM) protein has remained elusive. Here, we tested the ability of the three exocytic SM proteins expressed in the mammalian brain, MUNC18-1/2/3, to support neuropeptide secretion. Read More

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Parallel factor analysis of fluorescence excitation emissions to identify seasonal and watershed differences in trihalomethane precursors.

Chemosphere 2021 Jun 1;282:131061. Epub 2021 Jun 1.

Department of Environmental Engineering, Faculty of Engineering, Kasetsart University, Lad Yao, Chatuchak, Bangkok, 10903, Thailand.

Concentration and chemical composition of dissolved organic matter (DOM) play a major role in formation and speciation of disinfection by-products, such as trihalomethanes (THMs), in water treatment plants (WTPs) during disinfection. This study characterized DOM across the process trains of WTPs using fluorescence excitation emission matrices (EEMs) together with parallel factor analysis (PARAFAC). The PARAFAC model was developed from 216 EEMs of bimonthly water samples from three WTPs in Khon Kaen, Thailand, from May 2018 to Mar 2019. Read More

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Desertifilum sp. EAZ03 cell extract as a novel natural source for the biosynthesis of zinc oxide nanoparticles: its antibacterial, anticancer, and antibiofilm characteristics.

J Appl Microbiol 2021 Jun 8. Epub 2021 Jun 8.

Department of Energy & Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

Aims: The use of cyanobacterial cell extracts for the synthesis of zinc oxide nanoparticles seems to be superior to other methods of synthesis as a green, environmentally friendly, and low-cost approach. In the present study, the cell extract of a newly characterized cyanobacterial strain Desertifilum sp. EAZ03 was used for the biosynthesis of zinc oxide nanoparticles. Read More

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Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in .

Elife 2021 Jun 8;10. Epub 2021 Jun 8.

Molecular and Cell Biology, Physics, University of California, Berkeley, Berkeley, United States.

3D eukaryotic genome organization provides the structural basis for gene regulation. In , genome folding is characterized by somatic homolog pairing, where homologous chromosomes are intimately paired from end to end; however, how homologs identify one another and pair has remained mysterious. Recently, this process has been proposed to be driven by specifically interacting 'buttons' encoded along chromosomes. Read More

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Analysis of the tautomeric equilibrium of two red monoazo dyes by UV-Visible, Raman and SERS spectroscopies.

Spectrochim Acta A Mol Biomol Spectrosc 2021 May 26;261:120007. Epub 2021 May 26.

Instituto de Estructura de la Materia, IEM-CSIC, calle Serano 121, 28006 Madrid, Spain.

Acid Red 26 and Acid Red 18 are two early synthetic dyes belonging to the monazo dye class. The molecular structure of this class of dyes is characterized by the chromophoric azo group (NN) generally attached to benzene or naphthalene derivatives containing electron withdrawing and/or donating groups as substituents. As both red dyes have an OH group in ortho- position respect to the azo group, they undergo an azo-hydrazone tautomerism. Read More

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Physio-ultrastructural footprints and iTRAQ-based proteomic approach unravel the role of Piriformospora indica-colonization in counteracting cadmium toxicity in rice.

Ecotoxicol Environ Saf 2021 Jun 5;220:112390. Epub 2021 Jun 5.

Department of Agronomy, Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, PR China. Electronic address:

Due to its immense capability to concentrate in rice grain and ultimately in food chain, cadmium (Cd) has become the cause of an elevated concern among agriculturists, scientists and the environmental activists. Symbiotic association of Piriformospora indica (P. indica) has been characterized as a potential aid in combating heavy metal stress in plants for sustainable crop production but our scant knowledge regarding ameliorative tendency of P. Read More

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Quantitative or qualitative development in decision making?

J Exp Child Psychol 2021 Jun 4;210:105198. Epub 2021 Jun 4.

Department of Developmental Psychology, University of Amsterdam, 1001 NK Amsterdam, the Netherlands; Amsterdam Brain and Cognition Center, University of Amsterdam, 1001 NK Amsterdam, the Netherlands; Research Priority Area Yield, University of Amsterdam, 1018 WS Amsterdam, the Netherlands.

A key question in the developmental sciences is whether developmental differences are quantitative or qualitative. For example, does age increase the speed in processing a task (quantitative differences) or does age affect the way a task is processed (qualitative differences)? Until now, findings in the domain of decision making have been based on the assumption that developmental differences are either quantitative or qualitative. In the current study, we took a different approach in which we tested whether development is best described as being quantitative or qualitative. Read More

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