54 results match your criteria test st-5

Saudi Arabian nurses' workaholic tendencies and their predictive role in professional quality of life.

Perspect Psychiatr Care 2021 Jul 12. Epub 2021 Jul 12.

Department of Nursing, School of Nursing and Midwifery, Western Sydney University, Penrith, New South Wales, Australia.

Purpose: To determine whether nurses' workaholic tendencies and demographic variables predict their professional quality of life.

Design: A cross-sectional design was utilized among 427 Saudi nurses which conveniently selected in four tertiary public hospitals in Saudi Arabia.

Findings: Nurses' have higher workaholic tendencies level and moderate professional quality of life levels. Read More

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Triggering factors associated with a new episode of recurrent acute anterior uveitis.

Sci Rep 2021 Jun 9;11(1):12156. Epub 2021 Jun 9.

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.

To identify triggering factors for the next inflammatory episode of recurrent acute anterior uveitis (RAAU), a 1:1 case-control study was conducted. We interviewed RAAU patients with recent acute anterior uveitis attack and quiescent controls for their information during a previous month using Srithanya Stress Test (ST-5) and questionnaires about potential triggering factors. Asymptomatic controls were matched for age (± 5 years), sex, and HLA-B27. Read More

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Occult primary Sjögren Syndrome in patients with interstitial pneumonia with autoimmune features.

Respir Med 2021 06 20;182:106405. Epub 2021 Apr 20.

María Ferrer Hospital, Interstitial Lung Disease Unit, Buenos Aires, Argentina. Electronic address:

Introduction/objectives: To define the performance of Minor Salivary Gland Biopsy (MSGB) and Dry Eye Tests (DET) to detect occult Sjögren Syndrome (SS) among Interstitial Pneumonia with Autoimmune Features (IPAF) patients.

Methods: Prospective study. Interstitial Lung Disease (ILD) patients without defined Connective Tissue Disease and one or more IPAF classification domains or xerophthalmia were included. Read More

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Diagnostic value of Xpert Bladder Cancer Monitor in the follow-up of patients affected by non-muscle invasive bladder cancer: an update.

Ther Adv Urol 2021 Jan-Dec;13:1756287221997183. Epub 2021 Mar 5.

Department of Urology, Bolzano General Hospital, Lorenz Böhler St 5, Bolzano, 39100, Italy.

Aims: Xpert Bladder Cancer Monitor is a urinary marker based on the evaluation of five target mRNAs overexpressed in patients with bladder cancer (BC). The aim of our study is to update our results regarding the diagnostic accuracy of the Xpert Bladder Cancer Monitor test in the follow-up of patients with non-muscle invasive bladder cancer (NMIBC).

Methods: We conducted a prospective study on 1015 samples of 416 patients (mean age 72. Read More

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Anti-inflammatory effect of leaves of Vernonia zeylanica in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced rat paw-edema model.

J Ethnopharmacol 2021 Jun 17;274:114030. Epub 2021 Mar 17.

Institute of Biochemistry Molecular Biology and Biotechnology, University of Colombo, Sri Lanka. Electronic address:

Ethnopharmacological Relevance: Vernonia zeylanica (L.) Less (Family: Compositae) is a medicinal plant used as external applications for boils, bone fractures, eczema and internally for asthma in traditional medicine in Sri Lanka. Anti-nociceptive, anti-bacterial and anti-proliferative activities have been reported previously. Read More

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Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8--(12-Aminododecanoyl)-8--Debutanoylthapsigargin.

Biomolecules 2020 12 5;10(12). Epub 2020 Dec 5.

Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.

In spite of the impressing cytotoxicity of thapsigargin (), this compound cannot be used as a chemotherapeutic drug because of general toxicity, causing unacceptable side effects. Instead, a prodrug targeted towards tumors, mipsagargin, was brought into clinical trials. What substantially reduces the clinical potential is the limited access to Tg and its derivatives and cost-inefficient syntheses with unacceptably low yields. Read More

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December 2020

The Effect of Anesthesia Type During Delivery on Neonatal Otoacoustic Emission Hearing Test Results: A Tertiary Center Experience.

Z Geburtshilfe Neonatol 2021 Jun 29;225(3):262-266. Epub 2020 Sep 29.

Obstetrics and gynecology, Etlik İhtisas Eğitim ve Araştırma Hastanesi, Ankara, Turkey.

Background: Hearing is essential for the healthy development of an infant as language is one of the main stimulants of intellectual capacity. We investigate the effect of anesthesia type during delivery on neonatal otoacoustic emission (OAE) hearing test results.

Methods: This retrospective cross-sectional study includes 1,493 healthy, full-term (39/0-40/6 gestational weeks) newborns of healthy women and who were delivered by cesarean section. Read More

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Suspension training vs. traditional resistance training: effects on muscle mass, strength and functional performance in older adults.

Eur J Appl Physiol 2020 Oct 22;120(10):2223-2232. Epub 2020 Jul 22.

MUSCULAB, Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of São Carlos, UFSCar, Rod. Washington Luiz, km 235-SP 310, São Carlos, SP, 13565-905, Brazil.

Purpose: We compared the effects of suspension training (ST) with traditional resistance training (TRT) on muscle mass, strength and functional performance in older adults.

Methods: Forty-two untrained older adults were randomized in TRT, ST (both performed 3 sets of whole body exercises to muscle failure) or control group (CON). Muscle thickness (MT) of biceps brachii (MT) and vastus lateralis (MT), maximal dynamic strength test (1RM) for biceps curl (1RM) and leg extension exercises (1RM), and functional performance tests (chair stand [CS], timed up and go [TUG] and maximal gait speed [MGS]) were performed before and after 12 weeks of training. Read More

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October 2020

The impact of narratives and active video games on long-term moderate-to-vigorous physical activity: A randomized controlled trial protocol.

Contemp Clin Trials 2020 09 17;96:106087. Epub 2020 Jul 17.

Health Technology Lab, College of Arts, Media, and Design, Bouvé College of Health Sciences, Northeastern University, 360 Huntington Ave, Boston, MA 02115, United States. Electronic address:

Background: Although physical activity (PA) has been shown in helping prevent and treat obesity, current PA interventions are still not effective in ameliorating the obesity epidemic. Additional forms of PA need to be investigated to improve PA engagement and outcomes. We hypothesize that pairing a narrative (i. Read More

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September 2020

The incidence of occult ovarian neoplasia and cancer in BRCA1/2 mutation carriers after the bilateral prophylactic salpingo-oophorectomy (PBSO): A single-center prospective study.

Eur J Obstet Gynecol Reprod Biol 2020 Apr 30;247:26-31. Epub 2020 Jan 30.

Vilnius University Hospital Santaros Clinics, Hematology, Oncology and Transfusion Medicine Center, Hereditary Cancer Center, Santariskiu st. 2, Vilnius, Lithuania; State Research Institute Innovative Medicine Center, Santariskiu st. 5, Vilnius, Lithuania. Electronic address:

Background: Due to ineffective ovarian cancer (OC) screening programs, prophylactic bilateral salpingo-oophorectomy (PBSO) is suggested for BRCA1/2 genes mutation carriers. The reported incidence of clinically occult neoplasia and OC detected during PBSO varies widely (2-17 %), reflecting differences in studies design.

Objective: We aimed to prospectively evaluate the incidence of occult neoplasia in specimens collected during PBSO performed in a single tertiary center and to determine the effectiveness of this procedure in BRCA1/2 mutation carriers. Read More

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Schirmer test results: are they associated with topical or systemic medication?

Ocul Surf 2020 01 14;18(1):141-147. Epub 2019 Nov 14.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

Purpose: To test whether Schirmer test (ST) results are associated with topical or systemic medication and to evaluate the distribution of tear fluid quantity in a 3-min and 5-min ST.

Methods: The Gutenberg Health Study is a population-based, prospective, observational cohort study in Germany. ST was assessed in a sub-cohort of 1,999 participants. Read More

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January 2020

Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity.

Int J Mol Sci 2019 Sep 17;20(18). Epub 2019 Sep 17.

Department of Xenobiotics Biochemistry, Institute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.

Derivatives of tirapazamine and other heteroaromatic oxides (ArN→O) exhibit promising antibacterial, antiprotozoal, and tumoricidal activities. Their action is typically attributed to bioreductive activation and free radical generation. In this work, we aimed to clarify the mechanism(s) of aerobic mammalian cell cytotoxicity of ArN→O performing the parallel studies of their reactions with NADPH:cytochrome P-450 reductase (P-450R), adrenodoxin reductase/adrenodoxin (ADR/ADX), and NAD(P)H:quinone oxidoreductase (NQO1); we found that in P-450R and ADR/ADX-catalyzed single-electron reduction, the reactivity of ArN→O ( = 9) increased with their single-electron reduction midpoint potential (), and correlated with the reactivity of quinones. Read More

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September 2019

Stress and craving reduction under treatment with heart rate variability biofeedback and the Phramongkutklao model among patients with alcohol use disorder.

Psychol Res Behav Manag 2019 6;12:619-627. Epub 2019 Aug 6.

Department of Psychology and Neurology, Phramongkutklao College of Medicine, Bangkok, Thailand.

Background And Objective: Stress is an environmental cue, which may lead to increased alcohol craving, and vulnerability to relapse. Heart rate variability (HRV) biofeedback, a supplement standard for inpatient rehabilitation, has been applied for treatment and has been shown to effectively reduce craving and anxiety, increase HRV, and improve vasomotor function, among patients who have alcohol dependence problems. Therefore, the purpose of this study was to investigate the impact of HRV biofeedback and the Phramongkutklao model (PMK model) as an intensive inpatient rehabilitation program concerning stress and craving reduction of inpatients with alcohol use disorder. Read More

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Triethylene glycol-like effects of ( (L.) Dunal) root extract devoid of withanolides in stressed mice.

Ayu 2018 Oct-Dec;39(4):230-238

Department of Pharmaceutical Engineering and Technology (Formerly Department of Pharmaceutics), Indian Institute of Technology (Banaras Hindu University), Varanasi, Uttar Pradesh, India.

Background: The objective of the study is to compare stress resistance-promoting effect of triethylene glycol (TEG) and root extract of ( ) i.e. withanolide-free root extract of (WFWS). Read More

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Differentiation of treatment-related changes from tumour progression: a direct comparison between dynamic FET PET and ADC values obtained from DWI MRI.

Eur J Nucl Med Mol Imaging 2019 Aug 15;46(9):1889-1901. Epub 2019 Jun 15.

Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Background: Following brain cancer treatment, the capacity of anatomical MRI to differentiate neoplastic tissue from treatment-related changes (e.g., pseudoprogression) is limited. Read More

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A psychometric appraisal of the dundee ready education environment measure in a medical school in Chile.

Educ Health (Abingdon) 2018 Sep-Dec;31(3):148-154

Medical Faculty, University Diego Portales, Santiago, Chile.

Background: The Dundee Ready Education Environment Measure (DREEM) is used in the curricular development of future health professionals worldwide, but often without first locally testing its psychometric qualities, for example, construct validity and internal consistency. These characteristics are modified by different environments, but must be locally appropriate to obtain unequivocal and reliable conclusions about the strong and weak areas of a curriculum. Here, we report the results of the psychometric testing of DREEM results in our institution in Chile. Read More

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October 2019

Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients.

Curr Eye Res 2019 09 29;44(9):941-947. Epub 2019 Apr 29.

Department of Medical Biochemistry, Oslo University Hospital , Oslo , Norway.

: To investigate to what extent the OSDI can be utilized as a discriminative test for clinical findings. : One thousand and ninety patients with dry eye disease (DED) were consecutively included and examined for osmolarity, tear film break-up time (TFBUT), ocular protection index (OPI), ocular surface staining (OSS), Schirmer I test (ST), meibum expressibility (ME), meibum quality (MQ), and diagnosis of meibomian gland dysfunction (MGD). Receiver-operating characteristic curve (ROC) analysis considering optimum balanced sensitivity and specificity (close to 50%) was used for assessment. Read More

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September 2019

Antioxidant effects of gold nanoparticles on early stage of collagen-induced arthritis in rats.

Res Vet Sci 2019 Jun 18;124:32-37. Epub 2019 Feb 18.

State Research Institute Centre for Innovative Medicine, Santariskiu st. 5, LT-08406 Vilnius, Lithuania. Electronic address:

Objective: To determine antioxidant effects of prophylactic treatment with gold nanoparticles (AuNPs) in the early stage of collagen-induced arthritis (CIA).

Methods: The preventive treatment with 13 nm or 50 nm AuNPs injected intraarticularly (i.a. Read More

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Survival Rate and Predictors of Mortality among Hemodialysis Patients in West of Iran, 1996-2015.

Int J Prev Med 2018 24;9:113. Epub 2018 Dec 24.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Hemodialysis (HD) is one of the treatments provided to end-stage renal disease (ESRD) patients. A few studies have investigated the survival rate of HD patients in Iran. Hence, we decided to investigate the survival rate and it is predictors among Iranian ESRD patients. Read More

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December 2018

Effect of Reduced Material Thickness on Fatigue Behavior and Failure Load of Monolithic CAD/CAM PICN Molar Crowns.

Int J Prosthodont 2019 Jan/Feb;32(1):71-74

Purpose: To analyze the effect of material thickness on the fatigue behavior and failure load of monolithic polymer-infiltrated-ceramic-network (PICN) computer-aided design/computer-assisted manufacture (CAD/CAM) crowns.

Materials And Methods: PICN (VITA Enamic) molar crowns with standard (PICN-ST, 1.5 mm) and reduced (PICN-RED, 1. Read More

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October 2019

Using the Borg rating of perceived exertion scale to grade the intensity of a functional training program of the affected upper limb after a stroke: a feasibility study.

Clin Interv Aging 2019 19;14:9-16. Epub 2018 Dec 19.

University of Sherbrooke, School of Medicine and Health Sciences, School of Rehabilitation, Research Center on Aging, Sherbrooke, Québec, Canada,

Purpose: Intensity of a training program is a critical variable in treatment gains poststroke, but there are no guidelines to adequately dose the intensity of functional training (FT); the recommended type of training to promote poststroke recovery. Such guidelines are made available for strength training (ST) using the 1 repetition maximum (1RM), which has been linked to individuals' self-rated level of exertion using the Borg rating of perceived exertion (BRPE) scale. The BRPE could be a valuable tool for clinicians to dose FT intensity after a stroke, but this remains to be tested. Read More

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February 2019

An experimental study of amniotic lacrimal duct stents in the treatment of perimenopausal female rabbits with dry eye.

Mol Med Rep 2019 Feb 10;19(2):1056-1064. Epub 2018 Dec 10.

Department of Ophthalmology, Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

The aim of the present study was to investigate the effects of an amniotic membrane lacrimal stent in the treatment of dry eye syndrome in a perimenopausal rabbit model. In total, 48 healthy female rabbits were randomly divided into four groups (12 rabbits/group): Group A, sham‑operated group; group B, negative control group; group C, sham‑implantation group; and group D, implantation with amniotic membrane lacrimal stents. A Schirmer I test (SIT), corneal fluorescein staining, optical coherence tomography angiography and corneal confocal microscopy were conducted and the biomechanical properties of the amniotic membrane were measured prior to and 2, 4 and 6 weeks after the operations. Read More

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February 2019

Miniaturized microdosimeters as LET monitors: First comparison of calculated and experimental data performed at the 62 MeV/u C beam of INFN-LNS with four different detectors.

Phys Med 2018 Aug 18;52:113-121. Epub 2018 Jul 18.

INFN Laboratori Nazionali del Sud, via S.Sofia 62, 95123 Catania, Italy; ELI-National Physical Laboratory, CMES - Medical Radiation Science, Teddington, UK.

Purpose: The aim of this paper is to investigate the limits of LET monitoring of therapeutic carbon ion beams with miniaturized microdosimetric detectors.

Methods: Four different miniaturized microdosimeters have been used at the 62 MeV/u C beam of INFN Southern National Laboratory (LNS) of Catania for this purpose, i.e. Read More

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Molecular epidemiology and antimicrobial susceptibility of Clostridium difficile isolated from hospitals during a 4-year period in China.

J Med Microbiol 2018 Jan 21;67(1):52-59. Epub 2017 Nov 21.

Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, PR China.

Objective: The aim of this study was to perform molecular characterization for and determine the antimicrobial susceptibility profiles of Clostridium difficile collected from hospitals during a 4-year period (2009-2013) in China.

Methods: Strains of toxigenic C. difficile were isolated from patients with diarrhoea, and this was followed by typing using multilocus sequence typing (MLST) and testing for susceptibility to 10 antimicrobials by using the E-test. Read More

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January 2018

Comparison of Medical Therapy Alone to Medical Therapy with Surgical Treatment of Peritonsillar Abscess.

Otolaryngol Head Neck Surg 2018 02 7;158(2):280-286. Epub 2017 Nov 7.

1 Department of Otolaryngology/Head and Neck Surgery, Southern California Permanente Medical Group, San Diego, California, USA.

Objective This study was performed to determine whether the efficacy and safety of medical management of uncomplicated peritonsillar abscess (PTA) presenting in the emergency department is equivalent to medical plus surgical therapy. Study Design Case series with chart review. Setting Southern California Permanente Medical Group (SCPMG). Read More

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February 2018

Influence of Electroacupuncture and Laser-Acupuncture on Treating Paresthesia in Patients Submitted to Combined Orthognathic Surgery and Genioplasty.

Med Acupunct 2017 Oct;29(5):290-299

Special Laboratory of Lasers in Dentistry, Department of Restorative Dentistry, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil.

The goal of this research was to observe the influence of electroacupuncture (EA) and laser-acupuncture on the return of tactile/pain sensitivity in patients who underwent orthognathic surgery. Thirty volunteers subjected to orthognathic surgery were evaluated and randomly divided into 2 groups, in which 3 treatments were evaluated: control ( = 30) (G0, medication + placebo laser treatment) and 2 experimental treatments ( = 15) (G1, medication + EA) or G2 (medication + laser-acupuncture). The control group had  = 30 because for each experimental treatment conducted on a volunteer's hemi-face, there was a control treatment on the other hemi-face. Read More

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October 2017

The impact of high-dose narrowband ultraviolet A1 on dermal thickness, collagen and matrix-metalloproteinases in animal model of scleroderma.

J Photochem Photobiol B 2017 Aug 21;173:448-455. Epub 2017 Jun 21.

State Research Institute Centre for Innovative Medicine, Santariskiu St. 5, LT-08406 Vilnius, Lithuania; Vilnius University, Faculty of Medicine, Center of Rheumatology, Santariskiu St. 2, LT-08661 Vilnius, Lithuania. Electronic address:

Objective: The main purpose of the present study was to define the impact of high-dose of 365±5nm ultraviolet A1 (UVA1) on dermal fibrosis in the pre-established, bleomycin-induced mouse model of scleroderma.

Methods: DBA/2 strain mice with the pre-established, bleomycin-induced scleroderma were irradiated with cumulative UVA1 dose of 1200J/cm and in parallel were challenged with prolonged administration of bleomycin. Non-treated groups served as the control. Read More

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Low dose effects of a Withania somnifera extract on altered marble burying behavior in stressed mice.

J Intercult Ethnopharmacol 2016 Jun-Aug;5(3):274-7. Epub 2016 Apr 21.

Department of Pharmaceutics, Neuropharmacology Research Laboratory, Indian Institute of Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Aim: Withania somnifera root (WSR) extracts are often used in traditionally known Indian systems of medicine for prevention and cure of psychosomatic disorders. The reported experiment was designed to test whether low daily oral doses of such extracts are also effective in suppressing marble burying behavior in stressed mice or not.

Materials And Methods: Groups of mice treated with 10, 20, or 40 mg/kg daily oral doses of WSR were subjected to a foot shock stress-induced hyperthermia test on the 1(st), 5(th), 7(th), and 10(th) day of the experiment. Read More

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Grazing incidence off Rowland spectrometer with shifted slit.

Rev Sci Instrum 2016 05;87(5):053106

Intsitute of Spectroscopy of Russian Academy of Sciences, Fizicheskaya st. 5, Troitsk, Moscow 142190, Russia.

The article presents the analysis of the scheme of grazing incidence spectrometer with the normal to the line of site registration of the spectrum. The scheme is intended for the usage of the micro channel plate assembly as a spectrum detector. The main feature is the displacement of the entrance slit from the Rowland circle. Read More

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Training-Load-Guided vs Standardized Endurance Training in Recreational Runners.

Int J Sports Physiol Perform 2017 Mar 24;12(3):295-303. Epub 2016 Aug 24.

Purpose: To compare the effects of a standardized endurance-training program with individualized endurance training modified based on the cumulative training load provided by the Polar training-load feature.

Methods: After 12 wk of similar training, 24 recreationally endurance-trained men were matched to a training-load-guided (TL, n = 10) or standardized (ST, n = 14) group and continued training for 12 wk. In TL, training sessions were individually chosen daily based on an estimated cumulative training load, whereas in ST the training was standardized with 4-6 sessions/wk. Read More

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