173 results match your criteria test snt

The Carboxy Terminal Region on Spike Protein of Porcine Epidemic Diarrhea Virus (PEDV) Is Important for Evaluating Neutralizing Activity.

Pathogens 2021 May 31;10(6). Epub 2021 May 31.

Laboratory of Infectious Diseases, College of Veterinary Medicine, Chungnam National University, Daejon 34134, Korea.

In this study, we evaluated 62 sow sera samples from PED-vaccinated sows to compare the serum neutralizing test (SNT) and enzyme-linked immunosorbent assay (ELISA). We performed protein ELISA (pELISA) using fragments of spike proteins S1, S2, S3 and entire nucleocapsid proteins, and found a correlation between the SNT and ELISA in PEDV-vaccinated sera. Sera with higher neutralizing activity showed higher titers of IgG. Read More

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An application of probability density function for the analysis of PM2.5 concentration during the COVID-19 lockdown period.

Sci Total Environ 2021 Aug 27;782:146681. Epub 2021 Mar 27.

Department of Civil Engineering, IIT, Kanpur 208 016, India. Electronic address:

The first Covid-19 patient in India was reported on January 30, 2020 at the state of Kerala. The patient number rose to three by February 3, 2020. In the month of March 2020, the transmissions started to increase when the people started to return back to India from the Covid-19 affected countries. Read More

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On the Analysis of PM/FM Noise Radar Waveforms Considering Modulating Signals with Varied Stochastic Properties.

Sensors (Basel) 2021 Mar 3;21(5). Epub 2021 Mar 3.

Brazilian Army Technological Center, 23020-470 Rio de Janeiro, Brazil.

Noise Radar technology is the general term used to describe radar systems that employ realizations of a given stochastic process as transmit waveforms. Originally, carriers modulated in amplitude by a Gaussian random signal, derived from a hardware noise source, were taken into consideration, justifying the adopted nomenclature. With the advances made in hardware as well as the rise of the software defined noise radar concept, waveform design emerges as an important research area related to such systems. Read More

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SNT: a unifying toolbox for quantification of neuronal anatomy.

Nat Methods 2021 Apr 1;18(4):374-377. Epub 2021 Apr 1.

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.

SNT is an end-to-end framework for neuronal morphometry and whole-brain connectomics that supports tracing, proof-editing, visualization, quantification and modeling of neuroanatomy. With an open architecture, a large user base, community-based documentation, support for complex imagery and several model organisms, SNT is a flexible resource for the broad neuroscience community. SNT is both a desktop application and multi-language scripting library, and it is available through the Fiji distribution of ImageJ. Read More

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Titers of Neutralizing Antibodies against SARS-CoV-2 Are Independent of Symptoms of Non-Severe COVID-19 in Young Adults.

Viruses 2021 02 12;13(2). Epub 2021 Feb 12.

Swiss Armed Forces, Medical Services, Worblentalstrasse, 3063 Ittigen, Switzerland.

Neutralizing antibodies are an important part of the humoral immune response to SARS-CoV-2. It is currently unclear to what extent such antibodies are produced after non-severe disease or asymptomatic infection. We studied a cluster of SARS-CoV-2 infections among a homogeneous population of 332 predominantly male Swiss soldiers and determined the neutralizing antibody response with a serum neutralization assay using a recombinant SARS-CoV-2-GFP. Read More

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February 2021

Serological and Molecular Investigation of Batai Virus Infections in Ruminants from the State of Saxony-Anhalt, Germany, 2018.

Viruses 2021 02 26;13(3). Epub 2021 Feb 26.

Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.

Arthropod-borne Batai virus (BATV) is an widely distributed throughout European livestock and has, in the past, been linked to febrile diseases in humans. In Germany, BATV was found in mosquitoes and in one captive harbor seal, and antibodies were recently detected in various ruminant species. We have, therefore, conducted a follow-up study in ruminants from Saxony-Anhalt, the most affected region in Eastern Germany. Read More

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February 2021

Examining Mental Workload in a Spatial Navigation Transfer Game via Functional near Infrared Spectroscopy.

Brain Sci 2021 Jan 4;11(1). Epub 2021 Jan 4.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

The goal of this study was to examine the effects of task-related variables, such as the difficulty level, problem scenario, and experiment week, on performance and mental workload of 27 healthy adult subjects during problem solving within the spatial navigation transfer (SNT) game. The study reports task performance measures such as total time spent on a task (TT) and reaction time (RT); neurophysiological measures involving the use of functional near-infrared spectroscopy (fNIRS); and a subjective rating scale for self-assessment of mental workload (NASA TLX) to test the related hypotheses. Several within-subject repeated-measures factorial ANOVA models were developed to test the main hypothesis. Read More

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January 2021

The effects of preoperative moderate to severe anaemia on length of hospital stay: A propensity score-matched analysis in non-cardiac surgery patients.

Eur J Anaesthesiol 2021 06;38(6):571-581

From the Department of Anaesthesiology, Amsterdam UMC, VU University Amsterdam, Amsterdam, The Netherlands (CSE-B, CB), Department of Intensive Care and Laboratory of Experimental Intensive Care and Anaesthesia (L·E·I·C·A), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands (SNT-H, AS-N, JM-B, MJS), Department of Anaesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands (SNT-H, MW-H), Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paolo, Brazil (AS-N), Hedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden (GH), Montpellier University Hospital, Saint Eloi Intensive Care Unit and PhyMedExp, University of Montpellier, INSERM, CNRS, Montpellier, France (SJ), Division of Cardiac, Thoracic, Vascular Anaesthesia and Intensive Care, Medical University of Vienna, Vienna, Austria (MH, WS), Operating Services, Critical Care and Anaesthesia, Sheffield Teaching Hospitals, Sheffield and University of Sheffield, Sheffield, UK (GH-M), Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Bostan, MA, USA (MF-VM), Queen Mary University of London, London, UK (RM-P), Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany (CP), Department of Biotechnology and Sciences of Life, ASST Sette Laghi Ospedale di Circolo e Fondazione Macchi, University of Insubria, Varese, Italy (PS), Department of Anaesthesiology and Intensive Care Medicine, University of Leipzig, Leipzig, Germany (HW), Department of Anaesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany (MGD-A), Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate, Università degli Studi di Genova, Genova, Italy (PP), IRCCS Ospedale Policlinico San Martino, Genova, Italy (PP), Mahidol Oxford Tropical Medicine Research Unit (MORU), Mahidol University, Bangkok, Thailand (MJS), Nuffield Department of Medicine, University of Oxford, Oxford, UK (MJS).

Background: Anaemia is frequently recorded during preoperative screening and has been suggested to affect outcomes after surgery negatively.

Objectives: The objectives were to assess the frequency of moderate to severe anaemia and its association with length of hospital stay.

Design: Post hoc analysis of the international observational prospective 'Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study. Read More

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Hendra virus: Epidemiology dynamics in relation to climate change, diagnostic tests and control measures.

One Health 2021 Jun 21;12:100207. Epub 2020 Dec 21.

School of Veterinary Science, The University of Queensland, Gatton, QLD 4343, Australia.

Hendra virus (HeV) continues to pose a serious public health concern as spillover events occur sporadically. Terminally ill horses can exhibit a range of clinical signs including frothy nasal discharge, ataxia or forebrain signs. Early signs, if detected, can include depression, inappetence, colic or mild respiratory signs. Read More

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Presence of antibodies against tick-borne encephalitis virus in sheep in Tunisia, North Africa.

BMC Vet Res 2020 Nov 12;16(1):441. Epub 2020 Nov 12.

Laboratory of Infectious Animal Diseases, Zoonosis and Sanitary Regulation, Institution of Agricultural Research and Higher Education, Univ. Manouba, National School of Veterinary Medicine of Sidi Thabet, 2020, Sidi Thabet, Tunisia.

Background: Tick-borne encephalitis virus (TBEv) is a flavivirus that circulates in a complex cycle involving small mammals as amplifying hosts and ticks as vectors and reservoirs. The current study aimed to investigate the presence of TBEv in Tunisian sheep. A sample of 263 adult sheep were selected from 6 localities where Ixodes ricinus is well established. Read More

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November 2020

Stroop switching card test: brief screening of executive functions across the lifespan.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2020 Nov 8:1-20. Epub 2020 Nov 8.

Department of Informative and Operating Systems and Technologies, Uzhhorod National University, Uzhhorod, Ukraine.

This study aimed to: (1) propose a novel version of the Stroop switching test, namely the Stroop Switching Card Test (SSCT), to assess the overall efficiency of executive functions (EF) and its underlying cognitive processes (conflict resolution and conflict adaptation); (2) examine the utility of the SSCT in the assessment of EF in different age groups (age range 15-75 years), compare its results with standard neuropsychological tests (SNT), and (3) examine the contribution of both the processing speed and cognitive reserve on the performance of all used tests. The SSCT showed more sensitivity to detect subtle executive dysfunction in the middle age (~50 years). Going further, the SSCT revealed a progressive decline in conflict adaptation over two life periods. Read More

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November 2020

Comparative analysis of the course of infection and the immune response in rainbow trout (Oncorhynchus mykiss) infected with the 5 genotypes of infectious hematopoietic necrosis virus.

Virology 2021 Jan 6;552:20-31. Epub 2020 Oct 6.

French Agency for Food, Environmental and Occupational Health & Safety (ANSES), Ploufragan-Plouzané-Niort Laboratory, Fish Viral Pathology Unit, Technopôle Brest-Iroise, 29280, Plouzané, France.

Infectious hematopoietic necrosis virus (IHNV) is a pathogen of importance for salmonid aquaculture. In this study, we aimed to characterize virus behavior and defense mechanisms developed in rainbow trout (RT, Oncorhynchus mykiss) experimentally infected with isolates belonging to the five described genotypes of IHNV, i.e. Read More

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January 2021

Toxicity of Carbon, Silicon, and Metal-Based Nanoparticles to Sea Urchin Strongylocentrotus Intermedius.

Nanomaterials (Basel) 2020 Sep 13;10(9). Epub 2020 Sep 13.

Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, Russia.

With the increasing annual production of nanoparticles (NPs), the risks of their harmful influence on the environment and human health are rising. However, our knowledge about the mechanisms of interaction between NPs and living organisms is limited. Prior studies have shown that echinoderms, and especially sea urchins, represent one of the most suitable models for risk assessment in environmental nanotoxicology. Read More

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September 2020

Differential capacity of CD90+ cells in autophagy activation following chemotherapy in hepatocellular carcinoma.

Ann Hepatol 2020 Nov - Dec;19(6):645-652. Epub 2020 Aug 1.

Fondazione Italiana Fegato - ONLUS, AREA Science Park, Basovizza, Trieste, Italy; Laboratory of Molecular Biology and DNA repair, Department of Medicine (DAME), University of Udine, Udine, Italy. Electronic address:

Introduction And Objectives: Analysis of cancer biomarkers is an important tool in developing targeted-therapy and in modulating chemoresistance. Here, we analyze the relevance of CD90, a marker of cancer stem cells (CSC) in hepatocellular carcinoma (HCC) and its correlation with autophagy.

Materials And Methods: For in vivo study, 86 specimens were collected from 43 patients undergoing liver resections. Read More

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Relationship between calcium circulation-related factors and muscle strength in rat sciatic nerve injury model.

Iran J Basic Med Sci 2020 May;23(5):654-662

Department of Forensic Medicine, Xuzhou Medical University, Xuzhou, Jiangsu, P. R. China.

Objectives: The purpose of this study is to investigate the indication function of the calcium circulation-related factors on the damage to muscle strength and contraction function after nerve injury. The target factors include ryanodine receptor (RyR), inositol-1,4,5-triphosphate receptor (IP3R), phospholamban (PLN), cryptocalcitonin (CASQ), ATPase and troponin C (TNNC).

Materials And Methods: Sprague-Dawley (SD) rats were randomly divided into sham-operated group (SO), sciatic nerve injury group (SNI) and sciatic nerve disconnection group (SNT). Read More

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Using machine learning to assess the predictive potential of standardized nursing data for home healthcare case-mix classification.

Eur J Health Econ 2020 Nov 29;21(8):1121-1129. Epub 2020 Jun 29.

Dutch Healthcare Authority (NZa), Utrecht, The Netherlands.

Background: The Netherlands is currently investigating the feasibility of moving from fee-for-service to prospective payments for home healthcare, which would require a suitable case-mix system. In 2017, health insurers mandated a preliminary case-mix system as a first step towards generating information on client differences in relation to care use. Home healthcare providers have also increasingly adopted standardized nursing terminology (SNT) as part of their electronic health records (EHRs), providing novel data for predictive modelling. Read More

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November 2020

Immersive 3D Virtual Reality Cancellation Task for Visual Neglect Assessment: A Pilot Study.

Front Hum Neurosci 2020 25;14:180. Epub 2020 May 25.

Gerontechnology and Rehabilitation Group, University of Bern, Bern, Switzerland.

: Unilateral spatial neglectis an attention disorder frequently occurring after a right-hemispheric stroke. Neglect results in a reduction in qualityof life and performance in activities of daily living. With current technical improvements in virtual reality (VR) technology, trainingwith stereoscopic head-mounted displays (HMD) has become a promising new approach for the assessment and the rehabilitation of neglect. Read More

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Promotion of awareness and utilization of youth friendly service through multi-sectoral cooperation mechanism in China.

BMC Public Health 2020 May 24;20(1):747. Epub 2020 May 24.

National Center for Non-communicable Disease Prevention and Control, Chinese Center for Disease Control and Prevention, 27 Nanwei Road, Xicheng District, Beijing, People's Republic of China.

Background: Youth friendly services (YFS) was established in pilot areas in China. This study aimed to explore the promoting level on the awareness and utilization of YFS after the implementing of a multi-sectoral cooperation mechanism (MSCM) supported by social network theory (SNT) among multiple sectors related to young people reproductive health (YRH) closely.

Methods: A cross-sectional study with two separate self-administered questionnaire surveys was conducted before and after the implementing of a MSCM supported by SNT in both in-school and out-school unmarried young people aged 12-24 year-old in pilot areas in China. Read More

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Spatiotemporal monitoring of selected pathogens in Iberian ibex (Capra pyrenaica).

Transbound Emerg Dis 2020 Apr 17. Epub 2020 Apr 17.

Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Córdoba (UCO), Córdoba, Spain.

An epidemiological surveillance programme was carried out to assess exposure and spatiotemporal patterns of selected pathogens (Brucella spp., Mycobacterium avium subsp. paratuberculosis (MAP), Mycoplasma agalactiae, Pestivirus and bluetongue virus (BTV)) in Iberian ibex (Capra pyrenaica) from Andalusia (southern Spain), the region with the largest population of this species. Read More

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Evaluation of two enzyme-linked immunosorbent assays for diagnosis of bluetongue virus in wild ruminants.

Comp Immunol Microbiol Infect Dis 2020 Jun 29;70:101461. Epub 2020 Feb 29.

Departamento de Sanidad Animal, Facultad de Veterinaria, UCO, Campus Universitario de Rabanales, 14071 Córdoba, Spain.

Bluetongue (BT) is a reportable re-emerging vector-borne disease of animal health concern. Enzyme-linked immunosorbent assays (ELISA) are frequently used in BT surveillance programs in domestic ruminants, but their diagnostic accuracy has not been evaluated for wild ruminants, which can play an important role as natural reservoirs of bluetongue virus (BTV). The aim of this study was to assess two commercial ELISAs for BT diagnosis in wild ruminants using control sera of known BTV infection status and field samples. Read More

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Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag.

Pathogens 2020 Mar 4;9(3). Epub 2020 Mar 4.

Laboratory of Microbiology, Division of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.

A serum neutralization test (SNT) is an essential method for the serological diagnosis of pestivirus infections, including classical swine fever, because of the cross reactivity of antibodies against pestiviruses and the non-quantitative properties of antibodies in an enzyme-linked immunosorbent assay. In conventional SNTs, an immunoperoxidase assay or observation of cytopathic effect after incubation for 3 to 7 days is needed to determine the SNT titer, which requires labor-intensive or time-consuming procedures. Therefore, a new SNT, based on the luciferase system and using classical swine fever virus, bovine viral diarrhea virus, and border disease virus possessing the 11-amino-acid subunit derived from NanoLuc luciferase was developed and evaluated; this approach enabled the rapid and easy determination of the SNT titer using a luminometer. Read More

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A novel scoliosis instrumentation using special superelastic nickel-titanium shape memory rods: a biomechanical analysis using a calibrated computer model and data from a clinical trial.

Spine Deform 2020 06 24;8(3):369-379. Epub 2020 Feb 24.

Department of Mechanical Engineering, Polytechnique Montreal, Downtown Station, P.O. Box 6079, Montreal, QC, H3C 3A7, Canada.

Study Design: Biomechanical analysis of scoliosis instrumentation using superelastic Nickel-titanium shape memory (SNT) rods.

Objective: To compare SNT with conventional Titanium (Ti) and Cobalt-chrome (Co-Cr) rods. A clinical trial has documented comparable efficacy between two adolescent idiopathic scoliosis (AIS) cohorts instrumented using SNT versus conventional Ti rods. Read More

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Web-Supported Social Network Testing for HIV Among Men Who Have Sex With Men With a Migration Background: Protocol for a Mixed Methods Pilot Study.

JMIR Res Protoc 2020 02 9;9(2):e14743. Epub 2020 Feb 9.

Please see Authors' Contribution section for more information, .

Background: Of newly diagnosed HIV positive men who have sex with men (MSM) in the Netherlands, 29% have a non-Western migration background (MSM-NW). Among MSM-NW, HIV positivity rates are high (0.8%-2. Read More

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February 2020

Experimental infection of calves with seven serotypes of Epizootic Hemorrhagic Disease virus: production and characterization of reference sera.

Vet Ital 2019 Dec 31;55(4):339-346. Epub 2019 Dec 31.

UMR Virologie, INRA, Ecole Nationale Vétérinaire d'Alfort, laboratoire de santé animale d'Alfort, ANSES, Université Paris-Est, 94700 Maisons-Alfort, France.

The aim of this study was to produce reference sera against the seven serotypes of Epizootic hemorrhagic disease virus (EHDV‑1, EHDV‑2, EHDV‑4, EHDV‑5, EHDV‑6, EHDV‑7, and EHDV‑8). In a high containment unit, seven Prim 'Holstein calves were inoculated at day 0 (D0) with the selected strains (1 EHDV serotype per calf ). Blood samples (EDTA and whole blood) were periodically taken from D0 until the end of the experiment (D31). Read More

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December 2019

Sexual dimorphism in cognitive disorders in a murine model of neuropathic pain.

Behav Brain Funct 2020 Jan 4;16(1). Epub 2020 Jan 4.

Department of Neuroscience and Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.

Background: A sex-difference in susceptibility to chronic pain is well-known. Although recent studies have begun to reveal the sex-dependent mechanisms of nerve injury-induced pain sensitization, sex differences in the affective and cognitive brain dysfunctions associated with chronic pain have not been investigated. Therefore, we tested whether chronic pain leads to affective and cognitive disorders in a mouse neuropathic pain model and whether those disorders are sexually dimorphic. Read More

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January 2020

Cervids as sentinel-species for tick-borne encephalitis virus in Norway - A serological study.

Zoonoses Public Health 2020 06 19;67(4):342-351. Epub 2019 Dec 19.

Department of Virology, Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Tick-borne encephalitis virus (TBEV) is the causative agent of tick-borne encephalitis (TBE). TBEV is one of the most important neurological pathogens transmitted by tick bites in Europe. The objectives of this study were to investigate the seroprevalence of TBE antibodies in cervids in Norway and the possible emergence of new foci, and furthermore to evaluate if cervids can function as sentinel animals for the distribution of TBEV in the country. Read More

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Selective local anesthesia versus corticosteroid infiltration on low back pain: a randomized clinical trial.

Rev Esp Anestesiol Reanim (Engl Ed) 2020 Jan 24;67(1):1-7. Epub 2019 Nov 24.

Servicio de Neurocirugía, Hospital Central de la Defensa Gómez Ulla, Madrid, España.

Antecedents And Objective: Local infiltrations are second line therapy in the treatment of chronic low back pain, although their use is controversial in the literature. Our objective was to compare the effectiveness of 2 types of infiltration at the paravertebral lumbar level in two groups of patients diagnosed with low back pain: corticosteroids, and selective local anaesthetic administered using segmental neural therapy (SNT).

Material And Methods: Double-blind clinical trial in 55 patients diagnosed with low back pain in the neurosurgery department of the Hospital Central de la Defensa Gómez Ulla. Read More

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January 2020

Comparative immune responses of pups following modified live virus vaccinations against canine parvovirus.

Vet World 2019 Sep;12(9):1422-1427

Department of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry, India.

Background And Aim: Canine parvovirus (CPV) is the most important viral cause of enteritis and mortality in pups. Evaluation and monitoring of pre- and post-vaccine immune responses may help to determine the efficacy of the current vaccination schedule being followed in pups in India. This study aimed to evaluate and monitor the pre- and post-vaccine immune responses of CPV vaccinated pups using hemagglutination inhibition (HI) assay. Read More

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September 2019

Experimental lumpy skin disease virus infection of cattle: comparison of a field strain and a vaccine strain.

Arch Virol 2019 Dec 19;164(12):2931-2941. Epub 2019 Sep 19.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany.

Lumpy skin disease virus (LSDV) infections can cause massive clinical signs in cattle and have great economic impact due to severe trade restrictions. For LSDV control, only live attenuated vaccines are commercially available, but they currently are not authorized in the European Union. Moreover, these vaccine virus strains can induce substantial side effects with clinical signs similar to infections with virulent LSDV. Read More

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December 2019

Cognitive training and neuroplasticity in mild cognitive impairment (COG-IT): protocol for a two-site, blinded, randomised, controlled treatment trial.

BMJ Open 2019 08 30;9(8):e028536. Epub 2019 Aug 30.

Division of Geriatric Psychiatry, New York State Psychiatric Institute, New York, New York, USA

Introduction: Mild cognitive impairment (MCI) is common in older adults and represents a high-risk group for progression to Alzheimer's disease (AD). Medication trials in MCI have generally failed, but new discoveries with brain plasticity in ageing have led to the study of cognitive training as a potential treatment to improve cognitive abilities. Computerised cognitive training (CCT) involves computerised cognitive exercises that target specific cognitive abilities and neural networks to potentially improve cognitive functioning through neuroplasticity. Read More

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