162 results match your criteria terminal t-wave

[Clinical characteristics of patients with acute pulmonary embolism in high altitude area of Yunnan province in China].

Zhonghua Xin Xue Guan Bing Za Zhi 2022 Jan;50(1):36-42

Clinical Medicine Center and Key Laboratory for Cardiovascular Disease of Yunnan Province, Department of Cardiology, Yan'an Affiliated Hospital, Kunming Medical University, Kunming 650051, China.

To analyze the clinical features of patients with acute pulmonary embolism (APE) living in high altitude area of Yunnan province. This was a cross-sectional retrospective study. APE patients, hospitalized in our hospital between January 2017 and December 2019, were included. Read More

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January 2022

Terminal T-wave inversion predicts reperfusion tachyarrhythmias in STEMI.

J Electrocardiol 2022 Jan 5;71:28-31. Epub 2022 Jan 5.

Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden; Arrhythmia Clinic, Skåne University Hospital, 22185 Lund, Sweden.

Introduction: A reliable electrocardiographic predictor of ventricular fibrillation (VF) in patients with ST elevation myocardial infarction (STEMI) is lacking so far. Previous experimental/simulation study suggested a terminal T-wave inversion (TTWI) in ischemia-related ECG leads corresponding to anterior infarct localization as an independent predictor of reperfusion VF (rVF). This T-wave characteristic has never been tested as a rVF predictor in clinical settings. Read More

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January 2022

Single Dose of SHR-1222, a Sclerostin Monoclonal Antibody, in Healthy Men and Postmenopausal Women With Low Bone Mass: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation, Phase I Study.

Front Pharmacol 2021 20;12:770073. Epub 2021 Oct 20.

National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China.

SHR-1222 is a humanized monoclonal antibody targeting sclerostin and has the potential to promote bone formation and reduce bone resorption. This study was aimed to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of SHR-1222 in healthy men and postmenopausal women with low bone mass (BMD). It was a randomized, double-blind, placebo-controlled, dose-escalation, phase I study. Read More

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October 2021

Electrocardiographic Manifestations in Patients with COVID-19: Daegu in South Korea.

Korean Circ J 2021 Oct;51(10):851-862

Division of Cardiology, Daegu Catholic University College of Medicine, Daegu, Korea.

Background And Objectives: As the coronavirus disease 2019 (COVID-19) spreads worldwide, cardiac injury in patients infected with COVID-19 becomes a significant concern. Thus, this study investigates the impact of several electrocardiogram (ECG) parameters and disease severity in COVID-19 patients.

Methods: Seven medical centers in Daegu admitted 822 patients with COVID-19 between February and April 2020. Read More

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October 2021

Electrocardiographic biomarkers to predict atrial fibrillation in sinus rhythm electrocardiograms.

Heart 2021 11 4;107(22):1813-1819. Epub 2021 Jun 4.

Cardiology Department, Hospital Universitario de la Princesa, Madrid, Spain.

Objective: Early prediction of atrial fibrillation (AF) development would improve patient outcomes. We propose a simple and cheap ECG based score to predict AF development.

Methods: A cohort of 16 316 patients was analysed. Read More

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November 2021

Electrocardiographic Screening of Arrhythmogenic Cardiomyopathy in Genotype-Positive and Phenotype-Negative Relatives.

Front Cardiovasc Med 2021 7;8:646391. Epub 2021 May 7.

Department of Cardiology, Virgen de la Arrixaca University Hospital, Murcia, Spain.

Arrhythmogenic cardiomyopathy is a hereditary cause of ventricular arrhythmias and sudden death. Identifying the healthy genetic carriers who will develop the disease remains a challenge. A novel approach to the analysis of the digital electrocardiograms of mutation carriers through signal processing may identify early electrocardiographic abnormalities. Read More

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Detection of cardiac involvement in pulmonary sarcoidosis using high-resolution Holter electrocardiogram.

J Arrhythm 2021 Apr 12;37(2):438-444. Epub 2021 Jan 12.

Department of Cardiovascular Medicine Nippon Medical School Tokyo Japan.

Background: Early detection of cardiac involvement in patients with sarcoidosis is important but currently unresolved. The aim of this study was to elucidate the utility of frequency domain microvolt T-wave alternans (TWA), signal-averaged ECG (SAECG), and heart rate turbulence (HRT) using 24-hour Holter ECG for detecting cardiac involvement in patients with pulmonary sarcoidosis.

Methods: This study consisted of consecutive 40 pulmonary sarcoidosis patients (11 males, 62 ± 13 years) who underwent 24-hour Holter monitoring with and without cardiac involvement. Read More

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Quadruple episodes of takotsubo cardiomyopathy: a case report.

Eur Heart J Case Rep 2021 Jan 16;5(1):ytaa574. Epub 2021 Jan 16.

Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, Tokyo 183-0003, Japan.

Background: Takotsubo syndrome (TTS) is characterized by transient left ventricular (LV) dysfunction, often preceded by emotional or physical trigger. The recurrence of TTS has been investigated, however, cases of multiple recurrences are scarcely reported.

Case Summary: A 79-year-old woman was admitted to the hospital with the complaint of dyspnoea following emotional stress. Read More

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January 2021

COVID-19 cardiac injury and the use of colchicine.

BMJ Case Rep 2021 Feb 23;14(2). Epub 2021 Feb 23.

Infection Care Group, St George's University Hospitals NHS Foundation Trust, London, UK.

We report a case of cardiac injury in a 46-year-old man affected by COVID-19. The patient presented with shortness of breath and fever. ECG revealed sinus tachycardia with ventricular extrasystoles and T-wave inversion in anterior leads. Read More

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February 2021

Arrhythmogenic right ventricular cardiomyopathy in patients with biallelic JUP-associated skin fragility.

Sci Rep 2020 12 10;10(1):21622. Epub 2020 Dec 10.

Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

Arrhythmogenic right ventricular cardiomyopathy (ARVC), with skin manifestations, has been associated with mutations in JUP encoding plakoglobin. Genotype-phenotype correlations regarding the penetrance of cardiac involvement, and age of onset have not been well established. We examined a cohort of 362 families with skin fragility to screen for genetic mutations with next-generation sequencing-based methods. Read More

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December 2020

Cardio-protective impact of gabapentin against doxorubicin-induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling.

Int Immunopharmacol 2021 Jan 13;90:107125. Epub 2020 Nov 13.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt. Electronic address:

Purpose: Cardiotoxicity is one of the most commonly encountered adverse effects observed alongside the therapeutic use of doxorubicin (DOX), thus curbing its therapeutic utility.

Methods: The current study was conducted to evaluate the cardioprotective effect of gabapentin (Gaba), a Ca + 2 channel blocker with emerging pharmacological merits, against DOX-induced cardiotoxicity. Gaba was orally administered at two dose levels (10 and 30 mg/kg) for 21 days parallel to DOX injection. Read More

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January 2021

Body Surface Mapping of Ventricular Repolarization Heterogeneity: An Multiparameter Study.

Front Physiol 2020 13;11:933. Epub 2020 Aug 13.

Institute of Electrophysiology and Heart Modeling (IHU Liryc), Foundation Bordeaux University, Pessac-Bordeaux, France.

Background: Increased heterogeneity of ventricular repolarization is associated with life-threatening arrhythmia and sudden cardiac death (SCD). T-wave analysis through body surface potential mapping (BSPM) is a promising tool for risk stratification, but the clinical effectiveness of current electrocardiographic indices is still unclear, with limited experimental validation. This study aims to investigate performance of non-invasive state-of-the-art and novel T-wave markers for repolarization dispersion in an model. Read More

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Regadenoson Cardiac Stress Test-Induced Takotsubo Cardiomyopathy: A Case Report.

Cureus 2020 May 7;12(5):e8004. Epub 2020 May 7.

Cardiology, MedStar Washington Hospital Center, Washington, D.C., USA.

A 79-year-old female presented with acute left-sided chest pain with shortness of breath; she was afebrile and vitally stable. She had a mildly elevated troponin (0.11 ng/mL). Read More

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WCTECGdb: A 12-Lead Electrocardiography Dataset Recorded Simultaneously with Raw Exploring Electrodes' Potential Directly Referred to the Right Leg.

Sensors (Basel) 2020 Jun 8;20(11). Epub 2020 Jun 8.

School of Engineering, Western Sydney University Sydney, Kingswood, NSW 2747, Australia.

With this paper we communicated the existence of a surface electrocardiography (ECG) recordings dataset, named WCTECGdb, that aside from the standard 12-lead signals includes the raw electrode biopotential for each of the nine exploring electrodes refereed directly to the right leg. This dataset, comprises of 540 ten second segments recorded from 92 patients at Campbelltown Hospital, NSW Australia, and is now available for download from the Physionet platform. The data included in the dataset confirm that the Wilson's Central Terminal (WCT) has a relatively large amplitude (up to 247% of lead II) with standard ECG characteristics such as a -wave and a -wave, and is highly variable during the cardiac cycle. Read More

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The relationship between T-wave peak-to-end interval and hemodynamic parameters in patients with pulmonary arterial hypertension.

Ann Noninvasive Electrocardiol 2020 09 18;25(5):e12764. Epub 2020 Apr 18.

Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Background: T-wave peak-to-end interval (TPEI) is a measure of repolarization dispersion on surface electrocardiogram (ECG). TPEI has been reported as a prognostic parameter with heart disorders. In this study, we aimed to evaluate the relationship between echocardiogram-derived right heart parameters, right heart catheterization (RHC) measurements, and TPEI in patients with precapillary pulmonary arterial hypertension (PAH). Read More

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September 2020

Gastroesophageal reflux disease is associated with abnormal ventricular repolarization indices.

Turk J Gastroenterol 2019 Dec;30(12):1021-1024

Department of Gastroenterology, Adıyaman Training and Research Hospital, Adıyaman, Turkey.

Background/aims: Gastroesophageal Reflux Disease (GERD) is a clinical entity affecting the upper gastrointestinal tract. The pathophysiology of GERD has been associated with autonomic nervous system disorders. Autonomic nervous system disturbances in GERD patients have been shown to lead to fatal ventricular arrhythmias (VAs) that result in electrical and ventricular repolarization anomalies. Read More

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December 2019

A Rare Presentation of a Rare Entity: Wellens Syndrome with Subtle Terminal Wave Changes.

Case Rep Emerg Med 2019 16;2019:1582030. Epub 2019 Sep 16.

Department of Internal Medicine, West Virginia University Charleston Division, Charleston Area Medical Center, Charleston, WV, USA.

Wellens syndrome is an electrocardiographic (ECG) pattern involving waves in precordial leads that was first described in 1982 among a group of patients presenting with unstable angina suggestive of critical stenosis of the proximal left anterior descending (LAD) coronary. It is crucial for emergency physicians and internists to be able to recognize these patterns, as they occur in the symptom-free periods and represent a pre-infarction state that needs early intervention. Type A, which is characterized by biphasic waves, mainly in V2 and V3, poses a significant challenge to recognize the pattern, and failure to do so can lead to devastating outcome. Read More

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September 2019

Relationship Between Electrocardiographic Findings and Cardiac Magnetic Resonance Phenotypes in Arrhythmogenic Cardiomyopathy.

J Am Heart Assoc 2018 11;7(22):e009855

1 Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy.

Background The new designation of arrhythmogenic cardiomyopathy defines a broader spectrum of disease phenotypes, which include right dominant, biventricular, and left dominant variants. We evaluated the relationship between electrocardiographic findings and contrast-enhanced cardiac magnetic resonance phenotypes in arrhythmogenic cardiomyopathy. Methods and Results We studied a consecutive cohort of patients with a definite diagnosis of arrhythmogenic cardiomyopathy, according to 2010 International Task Force criteria, who underwent electrocardiography and contrast-enhanced cardiac magnetic resonance. Read More

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November 2018

Switching from ramipril to sacubitril/valsartan favorably alters electrocardiographic indices of ventricular repolarization in heart failure with reduced ejection fraction.

Acta Cardiol 2020 Feb 4;75(1):20-25. Epub 2018 Dec 4.

Department of Cardiology, Memorial Ankara Hospital, Ankara, Turkey.

Angiotensin receptor neprilysin inhibitor (ARNI, sacubitril/valsartan) reduces sudden death in heart failure with reduced ejection fraction (HFrEF). Corrected QT (QTc), T-wave peak to T-wave end interval (Tp-e) and Tp-e/QTc are electrocardiographic indices of ventricular repolarization heterogeneity. We aimed to assess the effects of switching from ramipril to ARNI on electrocardiographic indices of ventricular repolarization. Read More

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February 2020

P-wave terminal force in lead V1 is a predictive indicator for the diagnosis of tuberculous constrictive pericarditis.

Heart Lung 2019 Mar - Apr;48(2):155-158. Epub 2018 Oct 31.

Heart Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Qingchun East Road, Jianggan District, Hangzhou 310016, China. Electronic address:

Objectives: The purpose of this study is to explore the value of P-wave terminal force in lead V1 (PTFV1) in the clinical diagnosis of tuberculous constrictive pericarditis (TCP).

Methods: A total of 53 patients with TCP and 64 patients with tuberculous exudative pericarditis were enrolled in this retrospective study. The demographic and clinical characteristics were collected, including gender, age, the course of disease and New York Heart Association (NYHA) classification. Read More

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January 2020

Myocarditis and Early Markers of Cardiac Response Associated with Scorpion Stings in Children.

Wilderness Environ Med 2018 Dec 23;29(4):471-478. Epub 2018 Sep 23.

Department of Pediatric Emergency, School of Medicine, Çukurova University, Adana, Turkey (Drs Gökay, Kendir, Nalbant, and Prof Ylmaz).

Introduction: A clinical course ranging from mild local findings to life-threatening systemic findings may occur after scorpion stings. The purpose of this study was to identify priority markers indicating scorpion sting-related cardiac involvement.

Methods: Our study was performed between July 2014, and September 2015 in the Çukurova University medical faculty pediatric emergency department, in Adana, Turkey. Read More

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December 2018

Electrocardiographic differentiation between 'benign T-wave inversion' and arrhythmogenic right ventricular cardiomyopathy.

Europace 2019 Feb;21(2):332-338

Cardiology Clinical and Academic Group, St George's, University of London, Cranmer Terrace, London, UK.

Aims: To characterize the most common electrocardiographic (ECG) abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), including anterior T-wave inversion (TWI) and to compare the characteristics of TWI in patients with ARVC and in a cohort of young healthy athletes and sedentary individuals.

Methods And Results : The study population consisted of 162 patients with a definite diagnosis of ARVC and 129 young controls with anterior TWI. Cardiac disease was excluded in all controls after a comprehensive diagnostic work-up. Read More

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February 2019

Detection of Acute Myocardial Infarction in a Pig Model Using the SAN-Atrial-AVN-His (SAAH) Electrocardiogram (ECG), Model PHS-A10, an Automated and Integrated Signals Recognition System.

Med Sci Monit 2018 Mar 4;24:1303-1309. Epub 2018 Mar 4.

Division of Cardiology, Xiangtan Central Hospital, Xiangtan, Hunan, China (mainland).

BACKGROUND The aim of this study was to compare the use of the standard 12-lead electrocardiogram (ECG) with the SAN-Atrial-AVN-His (SAAH) ECG (Model PHS-A10), a new automated and integrated signals recognition system that detects micro-waveforms within the P, QRS, and T-wave, in a pig model of acute myocardial infarction (MI). MATERIAL AND METHODS Six medium-sized domestic Chinese pigs underwent general anesthesia, and an angioplasty balloon was placed and dilated for 120 minutes in the first diagonal coronary artery arising from the left anterior descending (LAD) coronary artery. A standard ECG and a SAAH ECG (Model PHS-A10) were used to evaluate: 1) the number of wavelets in ST-T segment in lead V5; 2) the duration of the repolarization initial (Ri), or duration of the wavelets starting from the J-point to the endpoint of the wavelets in the ST interval; 3) the duration of the repolarization terminal (Rt), of the wavelets, starting from the endpoint of the wavelets in the ST interval to the cross-point of the T-wave and baseline; 4) the ratio Ri: Rt. Read More

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Single Coronary Artery Anomaly: A Case Report and Review of Literature.

Cardiol Ther 2018 Jun 6;7(1):119-123. Epub 2018 Feb 6.

Department of Medicine, Division of Cardiology, University of Tennessee Health Science Center, Memphis, TN, USA.

Introduction: Single coronary artery is a rare anomaly, which is usually associated with other cardiac congenital abnormalities.

Case Report: A 56-year-old female presented with unstable angina. The patient reported complaints of typical chest pain on exertion few months prior to presentation, which progressed to become at rest. Read More

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Repolarization in perfused myocardium predicts reperfusion ventricular tachyarrhythmias.

J Electrocardiol 2018 May - Jun;51(3):542-548. Epub 2017 Dec 6.

Laboratory of Cardiac Physiology, Institute of Physiology, Komi Science Center, Ural Branch, Russian Academy of Sciences, Pervomayskaya st., 50, Syktyvkar, Russia; Department of Physiology, Medical Institute of Pitirim Sorokin Syktyvkar State University, Oktyabrskiy pr., 55, Syktyvkar, Russia.

Background: Aim of the study was to find out which myocardial repolarization parameters predict reperfusion ventricular tachycardia and fibrillation (VT/VF) and determine how these parameters express in ECG.

Methods: Coronary occlusion and reperfusion (30/30min) was induced in 24 cats. Local activation and end of repolarization times (RT) were measured in 88 intramyocardial leads. Read More

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Electrocardiographic alterations in patients consuming synthetic cannabinoids.

J Psychopharmacol 2018 03 7;32(3):296-301. Epub 2017 Nov 7.

2 Department of Cardiology, Ankara Education and Research Hospital, Turkey.

Introduction: The aim of this study was to investigate the electrocardiographic parameters in patients consuming synthetic cannabinoids.

Methods: Thirty-five patients who were consuming synthetic cannabinoids were enrolled to the study, prospectively. The control group included 35 healthy age and sex-matched volunteers. Read More

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Painless Mini-Wellens Sign 5 Minutes After Exercise in a Man With Previously Undiagnosed Total Occlusion of the Left Anterior Descending and Right Coronary Arteries.

Am J Cardiol 2017 Dec 5;120(11):2110-2112. Epub 2017 Sep 5.

Section of Cardiology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana. Electronic address:

A 60-year-old man with no coronary artery history and a normal resting electrocardiogram came to the hospital with his second stroke and underwent a treadmill exercise test before carotid endarterectomy. He had no chest pain and stopped because of leg pain. Five minutes after exercise he developed terminal T-wave inversion in leads V and V that lasted 7 minutes. Read More

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December 2017

Heart rate dependency of JT interval sections.

J Electrocardiol 2017 Nov - Dec;50(6):814-824. Epub 2017 Aug 9.

National Heart and Lung Institute, Imperial College, London, United Kingdom. Electronic address:

Background: Little experience exists with the heart rate correction of J-Tpeak and Tpeak-Tend intervals.

Methods: In a population of 176 female and 176 male healthy subjects aged 32.3±9. Read More

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Characterization of Aortic Valve Closure Artifact During Outflow Tract Mapping: Correlation With Hemodynamics and Mechanical Valves.

Circ Arrhythm Electrophysiol 2017 Jun;10(6)

From the UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine at UCLA (J.R., O.A., K.S., R.T.); and Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.R.).

Background: Premature ventricular contractions originating in the left ventricle outflow tract represent a significant subgroup of patients referred for catheter ablation. Mechanical artifacts from aortic valve leaflet motion may be observed during mapping, although the incidence and characteristics have not been reported.

Methods And Results: Twenty-eight consecutive patients with left ventricle outflow tract premature ventricular contraction were included. Read More

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Persistent T-wave inversion predicts myocardial damage after ST-elevation myocardial infarction.

Int J Cardiol 2017 Aug 5;241:76-82. Epub 2017 May 5.

University Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria. Electronic address:

Background: Persistent T-wave inversion (PTI) after ST-elevation myocardial infarction (STEMI) is associated with worse clinical outcome; however, the underlying mechanism between PTI and poor prognosis is incompletely understood. We sought to investigate the relationship between PTI and myocardial damage assessed by cardiac magnetic resonance (CMR) following STEMI.

Methods: In this prospective observational study, we included 142 consecutive revascularized STEMI patients. Read More

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