6,120 results match your criteria term singleton

Metabolites from mid-trimester plasma of pregnant patients at high-risk for preterm birth.

Am J Obstet Gynecol MFM 2021 May 12:100393. Epub 2021 May 12.

Institute for Environmental Health Solutions, Gillings School of Global Public Health, University of North Carolina-Chapel Hill, Chapel Hill, NC; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina-Chapel Hill, Chapel Hill, NC.

Background: There is an increased awareness regarding the association between exposure to environmental contaminants and adverse pregnancy outcomes including preterm birth. Whether an individual's metabolic profile can be utilized during pregnancy to differentiate the subset of patients who are ultimately destined to deliver preterm remains uncertain but could have significant clinical implications.

Objective: We sought to objectively quantify metabolomic profiles of patients at high risk for preterm birth by evaluating mid-trimester maternal plasma, and to measure whether endogenous metabolites and exogenous environmental substances differ among those who ultimately deliver preterm compared to those who deliver at term. Read More

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Rotational forceps: a retrospective study evaluating anatomical and functional consequences for the pelvic floor.

Int Urogynecol J 2021 May 15. Epub 2021 May 15.

Servicio de Ginecología y Obstetricia, Complejo Hospitalario Universitario Insular-Materno Infantil, Avenida Marítima del Sur, s/n, 35016, Las Palmas de Gran Canaria, Spain.

Introduction And Hypothesis: The use of Kielland's rotational forceps is considered to involve greater technical difficulty and may be associated with a higher rate of pelvic floor trauma. Our main objective was to evaluate the association between avulsion of the levator muscle and rotational and non-rotational forceps.

Methods: This was an observational study carried out at a tertiary hospital that recruited singleton cephalic vaginally primiparous women with previous Kielland's forceps delivery between March 2012 and May 2017. Read More

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Use of gestation adjusted projection method for predicting fetal head circumference.

J Matern Fetal Neonatal Med 2021 May 13:1-5. Epub 2021 May 13.

Department of Obstetrics and Gynecology, Albany Medical Center, Albany, NY, USA.

Objectives: The aim of this study is to determine if the gestation adjusted projection (GAP) method applied to a fetal head circumference (FHC) measured on ultrasound between 32 and 36 weeks and 6 days gestation can predict birth head circumference, specifically ≥ 35 cm, which is a known risk factor for Cesarean.

Methods: This is a retrospective chart review of 60 pregnancies from January to December 2019. Eligible patients delivered a singleton term neonate and received two ultrasounds, one at 32-36 weeks and 6 days gestation (period 1) and a second within 7 days of a term birth (period 2). Read More

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The impact of peak and duration of maternal intrapartum fever on perinatal outcomes.

Am J Obstet Gynecol MFM 2021 May 10:100390. Epub 2021 May 10.

Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Mount-Scopus, Jerusalem, Israel.

Objective: Intrapartum fever is a common perinatal complication, associated with short and long term adverse outcomes. Sparse data exists regarding the association between the peak and duration of maternal fever and the extent and severity of maternal and neonatal complications. This study aims to examine the association between maternal intrapartum fever peak and duration, and perinatal outcomes. Read More

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Association between Prenatal Care Adequacy Indexes and Low Birth Weight Outcome.

Rev Bras Ginecol Obstet 2021 Apr 12;43(4):256-263. Epub 2021 May 12.

Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Objective:  To investigate the association between prenatal care (PNC) adequacy indexes and the low birth weigth (LBW) outcome.

Methods:  A total of 368,093 live term singleton births in the state of Rio de Janeiro (Brazil) from 2015 to 2016 were investigated using data from the Brazilian Live Birth Information System (Sistema de Informações sobre Nascidos Vivos, SINASC, in Portuguese). Seven PNC adequacy indexes were evaluated: four developed by Brazilian authors (Ciari Jr. Read More

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Incidence and risk factors for severe preeclampsia, HELLP syndrome and eclampsia at preterm and term gestation: a population-based study.

Am J Obstet Gynecol 2021 May 8. Epub 2021 May 8.

Department of Obstetrics and Gynaecology, University of British Columbia, and the Children's and Women's Hospital and Health Centre of British Columbia, Vancouver, BC, Canada; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.

Background: A majority of previous studies of severe preeclampsia, eclampsia and HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome were hospital-based or included a relatively small number of women. Large population-based studies examining gestational age-specific incidence patterns and risk factors for these severe pregnancy complications are lacking.

Objectives: To assess gestational age-specific incidence rates and risk factors for severe preeclampsia, HELLP syndrome, and eclampsia. Read More

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Cesarean delivery at term for non-reassuring fetal heart rate tracing: risk factors and predictability.

J Matern Fetal Neonatal Med 2021 May 9:1-7. Epub 2021 May 9.

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Objective: To delineate risk factors for adverse outcomes among those who underwent cesarean delivery (CD) for non-reassuring fetal heart rate tracing (NRFHT) and ascertain whether neonatal or maternal morbidity can be predicted accurately.

Methods: The Consortium on Safe Labor Database was utilized for this secondary analysis. Inclusion criteria were non-anomalous, singleton gestations between 37. Read More

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The degree of cervical length shortening as a predictor of successful or failed labor induction.

Taiwan J Obstet Gynecol 2021 May;60(3):503-508

Department of Obstetrics and Gynecology, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

Objective: To evaluate whether the degree of cervical length change was associated with successful cervical dilatation during labor induction.

Materials And Methods: We conducted a secondary analysis of a prospective observational study of term singleton pregnant women who underwent labor inductions. Cases of Cesarean section due to fetal distress or maternal request during the first stage of labor were excluded. Read More

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The neonatal respiratory morbidity associated with early term caesarean section - an emerging pandemic.

J Perinat Med 2021 May 6. Epub 2021 May 6.

Department of Obstetrics and Gynecology, Women's Wellness and Research Centre, Hamad Medical Corporation, Doha, Qatar.

Objectives: To examine the impact of early term caesarean section (CS) on respiratory morbidity and early neonatal outcomes when elective caesarean section was carried out before 39 completed weeks gestation in our population.

Methods: A one-year population-based retrospective cohort analysis using routinely collected hospital data. Livebirths from women who had elective lower segment cesarean section (ELSCS) for uncomplicated singleton pregnancies at early term (ET) 37+0 to 38+6 weeks were compared to full term (FT)≥39+0 weeks gestation. Read More

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Delivery Mode After Manual Rotation of Occiput Posterior Fetal Positions: A Randomized Controlled Trial.

Obstet Gynecol 2021 May 6. Epub 2021 May 6.

Department of Obstetrics, the Department of Biostatistics and Methodology, the Department of Neonatal Medicine, the Department of Reproductive Medicine, Angers University Hospital, and the MITOVASC Institute, CNRS 6015, INSERM U1083, Angers University, Angers, and CESP-INSERM, U1018, Team 7, Reproductive and Sexual Health, Paris-Sud University, Kremlin-Bicêtre, France.

Objective: To evaluate whether manual rotation of fetuses in occiput posterior positions at full dilation increases the rate of spontaneous vaginal delivery.

Methods: In an open, single-center, randomized controlled trial, patients with a term, singleton gestation, epidural analgesia, and ultrasonogram-confirmed occiput posterior position at the start of the second stage of labor were randomized to either manual rotation or expectant management. Our primary endpoint was the rate of spontaneous vaginal delivery. Read More

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Differentiating Acute Rejection From Preeclampsia After Kidney Transplantation.

Obstet Gynecol 2021 May 6. Epub 2021 May 6.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California; Transplant Pregnancy Registry International, Gift of Life Institute, and the Section of Nephrology, Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania; the Department of Surgery, Lehigh Valley Health Network, Allentown, Pennsylvania; and the Department of Surgery, Morsani College of Medicine, Tampa, Florida.

Objective: To evaluate the clinical and laboratory characteristics in pregnancy that differentiate preeclampsia from acute renal allograft rejection and to investigate the maternal, neonatal, and graft sequelae of these diagnoses.

Methods: We conducted a retrospective case-controlled registry study of data abstracted from Transplant Pregnancy Registry International deliveries between 1968 and 2019. All adult kidney transplant recipients with singleton pregnancies of at least 20 weeks of gestation were included. Read More

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Dinoprostone pessary for labor induction in Chinese patients with premature rupture of membranes at term: A retrospective cohort.

J Obstet Gynaecol Res 2021 May 5. Epub 2021 May 5.

Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Aim: Whether the use of dinoprostone pessary increased the vaginal delivery rate of labor induction in Chinese nulliparous women with term premature rupture of membranes (PROM) and unfavorable cervices?

Methods: PROM women at term with singleton pregnancies and Bishop scores ≤4 who needed labor induction were enrolled in this retrospective study. They received either the dinoprostone pessary followed by oxytocin infusion if necessary (n = 102, PGE2 group) or oxytocin infusion alone (n = 103, oxytocin group).

Results: Compared with oxytocin infusion alone, vaginal delivery within 12 h and total vaginal delivery were higher in the PGE2 group (28. Read More

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Cervical ripening at home or in-hospital-prospective cohort study and process evaluation (CHOICE) study: a protocol.

BMJ Open 2021 May 4;11(5):e050452. Epub 2021 May 4.

Edinburgh Clinical Trials Unit (ECTU) Usher Institute, University of Edinburgh, Edinburgh, UK.

Introduction: The aim of the cervical ripening at home or in-hospital-prospective cohort study and process evaluation (CHOICE) study is to compare home versus in-hospital cervical ripening to determine whether home cervical ripening is safe (for the primary outcome of neonatal unit (NNU) admission), acceptable to women and cost-effective from the perspective of both women and the National Health Service (NHS).

Methods And Analysis: We will perform a prospective multicentre observational cohort study with an internal pilot phase. We will obtain data from electronic health records from at least 14 maternity units offering only in-hospital cervical ripening and 12 offering dinoprostone home cervical ripening. Read More

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Early term birth is associated with the risk of preterm and recurrent early term birth in women with 3 consecutive deliveries.

Eur J Obstet Gynecol Reprod Biol 2021 Apr 24;261:160-165. Epub 2021 Apr 24.

Department of Obstetrics and Gynecology, Lis Hospital for Women, Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel. Electronic address:

Background: We assessed the association of early term at first birth (ETB) with the risk of preterm birth (PTB) and ETB in women with 3 consecutive deliveries.

Methods: We conducted a retrospective cohort study of all women with 3 consecutive singleton births at a single institute from 1994 to 2013. The risk of PTB (<37 weeks), spontaneous PTB and ETB (37-38 weeks) in the 3 delivery was explored. Read More

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The effect of prenatal temperature and PM exposure on birthweight: Weekly windows of exposure throughout the pregnancy.

Environ Int 2021 Apr 30;155:106588. Epub 2021 Apr 30.

Icahn School of Medicine at Mount Sinai, Department of Environmental Medicine and Public Health, New York, NY, USA.

Background: Birthweight is a strong predictor of normal growth, healthy development, and survival. Several studies have found associations between temperature, fine particulate matter (PM), and birth weight. However, the relevant timing of exposures varies between studies and is yet unclear. Read More

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A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial.

Respirology 2021 May 3. Epub 2021 May 3.

School of Medicine, NIHR BRC University of Nottingham, University of Nottingham, Nottingham City Hospital, Nottingham, UK.

Background And Objective: Fractional exhaled nitric oxide (FeNO) is a non-invasive biomarker that reflects IL-4/IL-13 production and therefore represents T2 allergic inflammation. FeNO has previously been used to guide inhaled corticosteroid (ICS) treatment in asthma. The purpose of this study was to determine if a low FeNO (≤27 ppb) could be used to reliably identify patients with symptoms suggestive of asthma who would not benefit from initiating treatment with an ICS. Read More

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Association of Infant Physical Development and Rapid Growth With Pubertal Onset Among Girls in Rural China.

JAMA Netw Open 2021 May 3;4(5):e216831. Epub 2021 May 3.

Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.

Importance: Whether physical development and rapid growth during the first 2 years of life are associated with puberty onset in girls remains unclear.

Objective: To examine the associations of infant physical development and rapid growth with the timing of puberty onset in girls.

Design, Setting, And Participants: This prospective birth cohort study included girls whose mothers had participated in a randomized, double-blind cluster trial of micronutrient supplementation with a daily capsule of folic acid, iron and folic acid, or multiple micronutrients during pregnancy. Read More

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Efficacy of different infusion rates of oxytocin for maintaining uterine tone during elective caesarean section: A randomised double blind trial.

Anaesth Intensive Care 2021 May 2:310057X20984480. Epub 2021 May 2.

Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.

Most research in this field has focused on finding oxytocin doses for initiating uterine contractions. Only limited data are available regarding the optimal rate of oxytocin infusion to maintain adequate uterine tone. This randomised, double blind study included 120 healthy term pregnant patients with uncomplicated, singleton pregnancy undergoing elective caesarean section under spinal anaesthesia. Read More

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Is Exposure to Intrapartum Prostaglandins for Labor Induction Associated with a Lower Incidence of Neonatal Respiratory Distress Syndrome?

Am J Perinatol 2021 May 2. Epub 2021 May 2.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah.

Objective:  Respiratory distress syndrome (RDS) is implicated in 30% of neonatal deaths. Since prostaglandins promote surfactant secretion and labor is associated with a lower risk of RDS in term neonates, it is plausible that synthetic prostaglandin (sPG) exposure is associated with a lower risk of RDS. Thus, we evaluated the association between sPG exposure and RDS in neonates born after the induction of labor (IOL). Read More

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Literature Review of the Association Between Prenatal Education and Rates of Cesarean Birth Among Women at Low Risk.

Sabrina Ronco

Nurs Womens Health 2021 Apr 29. Epub 2021 Apr 29.

A review of the literature was performed to explore the association between prenatal education and rates of primary cesarean birth for women at low risk for cesarean birth. Most women who are nulliparous with a singleton fetus of term gestational age and in the vertex position are considered to be at low risk and favorable for a vaginal birth, yet the cesarean birth rate for women at low risk was 25.6% in 2019. Read More

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A multi-center longitudinal study on responsive breastfeeding in China from the perspective of health equity: research protocol.

Int J Equity Health 2021 May 1;20(1):111. Epub 2021 May 1.

Department of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, No.10 You'anmenwai Xitoutiao, Fengtai District, Beijing, 100069, China.

Background: Socio-economic inequities can strongly influence suboptimal infant feeding outcomes. Factors such as lack of knowledge about breastfeeding, low family income, low educational attainment, social and economic status, cultural norms and ethnicity may negatively affect success with offering breastfeeding following a responsive feeding approach (ie. responsive breastfeeding). Read More

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The association between preterm birth and postpartum mental health care utilization among California birthing people.

Am J Obstet Gynecol MFM 2021 Apr 28:100380. Epub 2021 Apr 28.

California Preterm Birth Initiative, University of California San Francisco, San Francisco, CA; Department of Pediatrics, University of California San Francisco, San Francisco, CA.

Background: While birthing person's mental health conditions such as postpartum depression are common, little is known about how mental health care utilization varies postpartum based on whether or not an infant is born preterm.

Objective: To determine whether preterm birth is associated with postpartum inpatient and emergency mental health care utilization.

Study Design: Data were obtained from a database of liveborn neonates born in California between the years of 2011-2017. Read More

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Maternal obesity and stillbirth at term; placental pathology-A case control study.

PLoS One 2021 30;16(4):e0250983. Epub 2021 Apr 30.

Dep of Laboratory Medicine, Karolinska University Hospital Huddinge, Huddinge, Sweden.

Objective: The aim was to explore the potential role of the placenta for the risk of stillbirth at term in pregnancies of obese women.

Methods: This was a case-control study comparing placental findings from term stillbirths with placental findings from live born infants. Cases were singleton term stillbirths to normal weight or obese women, identified in the Stockholm stillbirth database, n = 264 and n = 87, respectively. Read More

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Improvement of Vision and Ocular Surface Symptoms With a Scleral Lens After Microbial Keratitis.

Eye Contact Lens 2021 Apr 27. Epub 2021 Apr 27.

Clinical and Experimental Optometry Research Lab (CEORLab) (R.J.M.-d.-A., J.M.G.-M.), Center of Physics, University of Minho, Braga, Portugal; Department of Ophthalmology (C.M.), Singleton Hospital, Swansea Bay University Health Board, Swansea, United Kingdom; School of Ophthalmology and Optometry and Eye Hospital (C.M.), Wenzhou Medical University, Wenzhou, China; and Eye-Contact-Lens Research and Education (E.v.d.W.), Amsterdam, the Netherlands.

Abstract: A 38-year-old woman, previous daily disposable soft contact lens wearer, reported an episode of microbial keratitis positive for Pseudomonas aeruginosa 11 months before contacting the investigators. After acute treatment, she was left with a degree of opacity in the pupillary area, corneal scar, and an irregular corneal profile, with a best spectacle visual acuity of +0.48 logarithm of the minimum angle of resolution. Read More

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The human dimension of biodiversity changes on islands.

Science 2021 04;372(6541):488-491

Bayreuth Center of Ecology and Environmental Research (BayCEER) and Department of Sport Science, University of Bayreuth, 95447 Bayreuth, Germany.

Islands are among the last regions on Earth settled and transformed by human activities, and they provide replicated model systems for analysis of how people affect ecological functions. By analyzing 27 representative fossil pollen sequences encompassing the past 5000 years from islands globally, we quantified the rates of vegetation compositional change before and after human arrival. After human arrival, rates of turnover accelerate by a median factor of 11, with faster rates on islands colonized in the past 1500 years than for those colonized earlier. Read More

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Placental Antioxidant Defenses and Autophagy-Related Genes in Maternal Obesity and Gestational Diabetes Mellitus.

Nutrients 2021 Apr 15;13(4). Epub 2021 Apr 15.

Department of Biomedical and Clinical Sciences "Luigi Sacco", Università degli Studi di Milano, 20157 Milano, Italy.

Maternal obesity and gestational diabetes mellitus (GDM) are increasing worldwide, representing risk factors for both mother and child short/long-term outcomes. Oxidative stress, lipotoxicity and altered autophagy have already been reported in obesity, but few studies have focused on obese pregnant women with GDM. Antioxidant and macro/chaperone-mediated autophagy (CMA)-related gene expressions were evaluated herein in obese and GDM placentas. Read More

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Can We Predict Preterm Delivery Based on the Previous Pregnancy?

J Clin Med 2021 Apr 5;10(7). Epub 2021 Apr 5.

Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8489325, Israel.

(1) Background: Preterm deliveries (PTD, <37 gestational weeks) which occur in 5-18% of deliveries across the world, are associated with immediate and long-term offspring morbidity, as well as high costs to health systems. Our aim was to identify risk factors during the first pregnancy ending at term for PTD in the subsequent pregnancy. (2) Methods: A retrospective population- based nested case-control study was conducted, including all women with two first singleton consecutive deliveries. Read More

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Does Delayed Cord Clamping Improve Long-Term (≥4 Months) Neurodevelopment in Term Babies? A Systematic Review and a Meta-Analysis of Randomized Clinical Trials.

Front Pediatr 2021 12;9:651410. Epub 2021 Apr 12.

Clinic of Obstetrics and Gynecology, University Hospital of Udine, Udine, Italy.

Recently, the literature suggested that placental transfusion facilitated by delayed cord clamping (DCC), besides having benefits on hematological parameters, might improve the infants' brain development. The present review primarily evaluates the Ages and Stages Questionnaire (ASQ) total score mean difference (MD) at long-term follow-up (≥4 months) comparing DCC (>90 or >180 s) to early cord clamping (ECC). Secondary aims consisted of evaluating the ASQ domains' MD and the results obtained from other methods adopted to evaluate the infants' neurodevelopment. Read More

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Influence of paternal age on assisted reproductive technology cycles and perinatal outcomes.

Fertil Steril 2021 Apr 25. Epub 2021 Apr 25.

Department of Urology, Emory University School of Medicine, Atlanta, Georgia.

Objective: To characterize paternal age among assisted reproductive technology (ART) cycles performed in the United States and to evaluate the influence of paternal age on ART cycles and perinatal outcomes.

Design: Retrospective cohort.

Setting: Not applicable. Read More

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Central Australian Aboriginal women's pregnancy, labour and birth outcomes following maternal smokeless tobacco (pituri) use, cigarette use or no-tobacco use: a prospective cohort study.

BMC Public Health 2021 Apr 28;21(1):814. Epub 2021 Apr 28.

Associate Professor School of Pharmacy, The University of Queensland, Brisbane, Queensland, 4102, Australia.

Background: Outcomes related to maternal smoked tobacco (cigarette) use have been substantially examined over the past 50 years with resultant public health education targeted towards the reduction of use during pregnancy. However, worldwide the effects of maternal smokeless tobacco use have been less well explored and in Australia, there has been no examination of maternal outcomes in relation to the use of Australian Nicotiana spp. (tobacco plant) as a smokeless tobacco, colloquially known as pituri. Read More

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