3,174 results match your criteria temporal coordination

Effect of Thoracic Connective Lesion on Inter-Leg Coordination in Freely Walking Stick Insects.

Front Bioeng Biotechnol 2021 20;9:628998. Epub 2021 Apr 20.

Department of Biological Cybernetics, Faculty of Biology, Bielefeld University, Bielefeld, Germany.

Multi-legged locomotion requires appropriate coordination of all legs with coincident ground contact. Whereas behaviourally derived coordination rules can adequately describe many aspects of inter-leg coordination, the neural mechanisms underlying these rules are still not entirely clear. The fact that inter-leg coordination is strongly affected by cut thoracic connectives in tethered walking insects, shows that neural information exchange among legs is important. Read More

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A Spatio-temporal Attention-based Model for Infant Movement Assessment from Videos.

IEEE J Biomed Health Inform 2021 May 6;PP. Epub 2021 May 6.

The absence or abnormality of fidgety movements of joints or limbs is strongly indicative of cerebral palsy in infants. Developing computer-based methods for assessing infant movements in videos is pivotal for improved cerebral palsy screening. Most existing methods use appearance-based features and are thus sensitive to strong but irrelevant signals caused by background clutter or a moving camera. Read More

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Effects of gait rehabilitation on motor coordination in stroke survivors: an UCM-based approach.

Exp Brain Res 2021 May 6. Epub 2021 May 6.

The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy.

Post-stroke locomotion is usually characterized by asymmetrical gait patterns, compensatory movements of trunk and nonparetic limb, altered motor coordination, and wide inter-stride variability. This pilot study was designed to test a twofold hypothesis: post-stroke survivors can exploit the redundancy of the segmental angles to stabilize the 3D footpath trajectory during the swing phase, in accordance with the Uncontrolled Manifold (UCM) theory; an intense rehabilitative treatment improves both motor performance and outcomes of the UCM analysis. Ten stroke survivors underwent two evaluation sessions, before and after a conventional multidisciplinary intensive rehabilitation program, encompassing clinical tests and gait analysis, both overground and on treadmill. Read More

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Electrophysiological indicators of sleep-associated memory consolidation in 5- to 6-year-old children.

Psychophysiology 2021 May 5:e13829. Epub 2021 May 5.

Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.

In adults, the synchronized interplay of sleep spindles (SP) and slow oscillations (SO) supports memory consolidation. Given tremendous developmental changes in SP and SO morphology, it remains elusive whether across childhood the same mechanisms as identified in adults are functional. Based on topography and frequency, we characterize slow and fast SPs and their temporal coupling to SOs in 24 pre-school children. Read More

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Nano-enabled coordination platform of bismuth nitrate and cisplatin prodrug potentiates cancer chemoradiotherapy DNA damage enhancement.

Biomater Sci 2021 May;9(9):3401-3409

Zhuhai Interventional Medical Center, Zhuhai Precision Medical Center, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, Zhuhai 519000, China.

The combination of chemotherapy and radiotherapy (chemoradiotherapy) is a promising strategy, extensively studied and applied clinically. Meanwhile, radiosensitizers play an important role in improving clinical radiotherapy therapeutic efficacy. There are still some disadvantages in practical applications, because radiosensitizers and drugs are difficult to deliver spatio-temporally to tumor sites and work simultaneously with low efficiency for DNA damage and repair inhibition, leading to an inferior synergistic effect. Read More

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Microfluidic valvular chips and a numerical lymphatic vessel model for the study of lymph transport characteristics.

Lab Chip 2021 May 4. Epub 2021 May 4.

Department of Chemical and Biomolecular Engineering, Sogang University, Seoul, South Korea.

Lymph transport inside lymphatic vessels is highly complex and not yet fully understood. So far, a consensus has not been reached among existing analytical models on how spatiotemporal coordination of contracting adjacent lymphangions affects lymph transport. To understand complex lymph transport, we created a novel microfluidic valvular chip with flexible bicuspid valves and segmental pneumatic pumps based on a microfluidic device with an inside 3D structure made of hydrogels. Read More

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Detecting structural and functional neuroplasticity in elite ice-skating athletes.

Hum Mov Sci 2021 Apr 30;78:102795. Epub 2021 Apr 30.

Division of Sports Science and Physical Education, Tsinghua University, Beijing 100084, PR China. Electronic address:

Using resting-state fMRI, this study investigated long-term ice-skating training related changes in elite ice-skating athletes and compared them to healthy age-matched non-athletes under resting-state conditions. Significant differences were found in both structural and functional plasticity. Specifically, elite ice-skating athletes showed higher gray matter volume in the posterior cerebellum, frontal lobe, temporal lobe, posterior cingulate, caudate, and thalamus. Read More

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Altered interhemispheric functional homotopy and connectivity in temporal lobe epilepsy based on fMRI and multivariate pattern analysis.

Neuroradiology 2021 May 3. Epub 2021 May 3.

Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Purpose: This study aimed to investigate how the functional homotopy and further functional connectivity (FC) of whole brain changed in temporal lobe epilepsy (TLE). We also evaluated which brain regions played a decisive role in classification by using functional magnetic resonance imaging (fMRI).

Methods: Patients with TLE and matched healthy controls were included to collect the fMRI data and perform the voxel-mirrored homotopic connectivity (VMHC) and FC analyses. Read More

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The Dynamic SecYEG Translocon.

Front Mol Biosci 2021 15;8:664241. Epub 2021 Apr 15.

Institute for Biochemistry and Molecular Biology, Zentrum für Biochemie und Molekulare Medizin (ZMBZ), Faculty of Medicine, Albert Ludwigs Universität Freiburg, Freiburg, Germany.

The spatial and temporal coordination of protein transport is an essential cornerstone of the bacterial adaptation to different environmental conditions. By adjusting the protein composition of extra-cytosolic compartments, like the inner and outer membranes or the periplasmic space, protein transport mechanisms help shaping protein homeostasis in response to various metabolic cues. The universally conserved SecYEG translocon acts at the center of bacterial protein transport and mediates the translocation of newly synthesized proteins into and across the cytoplasmic membrane. Read More

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An Approach to Aligning Categorical and Continuous Time Series for Studying the Dynamics of Complex Human Behavior.

Front Psychol 2021 16;12:614431. Epub 2021 Apr 16.

Faculty of Human Sciences, Waseda University, Saitama, Japan.

An emerging perspective on human cognition and performance sees it as a kind of self-organizing phenomenon involving dynamic coordination across the body, brain and environment. Measuring this coordination faces a major challenge. Time series obtained from such cognitive, behavioral, and physiological coordination are often complicated in terms of non-stationarity and non-linearity, and in terms of continuous vs. Read More

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Multifractal Dynamics in Executive Control When Adapting to Concurrent Motor Tasks.

Laurent M Arsac

Front Physiol 2021 16;12:662076. Epub 2021 Apr 16.

Université de Bordeaux, CNRS, Laboratoire IMS, UMR 5218, Talence, France.

There is some evidence that an improved understanding of executive control in the human movement system could be gained from explorations based on scale-free, fractal analysis of cyclic motor time series. Such analyses capture non-linear fractal dynamics in temporal fluctuations of motor instances that are believed to reflect how executive control enlist a coordination of multiple interactions across temporal scales between the brain, the body and the task environment, an essential architecture for adaptation. Here by recruiting elite rugby players with high motor skills and submitting them to the execution of rhythmic motor tasks involving legs and arms concurrently, the main attempt was to build on the multifractal formalism of movement control to show a marginal need of effective adaptation in concurrent tasks, and a preserved adaptability despite complexified motor execution. Read More

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The coordination of spindle-positioning forces during the asymmetric division of the Caenorhabditis elegans zygote.

EMBO Rep 2021 May 26;22(5):e50770. Epub 2021 Apr 26.

CNRS, IGDR - UMR 6290, University of Rennes, Rennes, France.

In Caenorhabditis elegans zygote, astral microtubules generate forces essential to position the mitotic spindle, by pushing against and pulling from the cortex. Measuring microtubule dynamics there, we revealed the presence of two populations, corresponding to pulling and pushing events. It offers a unique opportunity to study, under physiological conditions, the variations of both spindle-positioning forces along space and time. Read More

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Multiple Cellular Therapies Along with Neurorehabilitation in Spastic Diplegic Cerebral Palsy: A Case Report.

Innov Clin Neurosci 2020 Oct-Dec;17(10-12):31-34. Epub 2020 Oct 1.

Drs. Sharma and Gokulchandran are with the Department of Medical Services and Clinical Research at NeuroGen Brain and Spine Institute in Navi Mumbai, India.

Cerebral palsy (CP) is a chronic childhood disorder that is characterized by a group of motor and cognitive impairments, resulting in abnormal movement patterns, loss of motor control, incoordination, and unbalanced posture. It can also have an impact on fine motor skills, gross motor skills, and oral motor functioning. Currently, the treatment of CP is palliative and does not cure the disease pathology. Read More

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October 2020

Introducing Social Breathing: A Model of Engaging in Relational Systems.

Front Psychol 2021 8;12:571298. Epub 2021 Apr 8.

Family Studies and Human Development, University of Arizona, Tucson, AZ, United States.

We address what it means to "engage in a relationship" and suggest Social Breathing as a model of immersing ourselves in the metaphorical social air around us, which is necessary for shared intention and joint action. We emphasize how emergent properties of social systems arise, such as the shared culture of groups, which cannot be reduced to the individuals involved. We argue that the processes involved in Social Breathing are: (1) automatic, (2) implicit, (3) temporal, (4) in the form of mutual bi-directional interwoven exchanges between social partners and (5) embodied in the coordination of the brains and behaviors of social partners. Read More

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A three-dimensional vertex model for Drosophila salivary gland invagination.

Phys Biol 2021 Apr 21. Epub 2021 Apr 21.

The University of British Columbia, 1984 Mathematics Road, Vancouver, British Columbia, V6T 1Z4, CANADA.

During epithelial morphogenesis, force generation at the cellular level not only causes cell deformation, but may also produce coordinated cell movement and rearrangement on the tissue level. In this paper, we use a novel three-dimensional vertex model to explore the roles of cellular forces during the formation of the salivary gland in the Drosophila embryo. Representing the placode as an epithelial sheet of initially columnar cells, we focus on the spatial and temporal patterning of contractile forces due to three actomyosin pools: the apicomedial actomyosin in the pit of the placode, junctional actomyosin arcs outside the pit, and a supracellular actomyosin cable along the circumference of the placode. Read More

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Synchronous Brain Dynamics Establish Brief States of Communality in Distant Neuronal Populations.

eNeuro 2021 May-Jun;8(3). Epub 2021 May 6.

Functional Brain Mapping Lab, Department of Fundamental Neuroscience, Campus Biotech, University of Geneva, Geneva 1202, Switzerland

Intrinsic brain dynamics co-fluctuate between distant regions in an organized manner during rest, establishing large-scale functional networks. We investigate these brain dynamics on a millisecond time scale by focusing on electroencephalographic (EEG) source analyses. While synchrony is thought of as a neuronal mechanism grouping distant neuronal populations into assemblies, the relevance of simultaneous zero-lag synchronization between brain areas in humans remains largely unexplored. Read More

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The Differential Effects of Auditory and Visual Stimuli on Learning, Retention and Reactivation of a Perceptual-Motor Temporal Sequence in Children With Developmental Coordination Disorder.

Front Hum Neurosci 2021 31;15:616795. Epub 2021 Mar 31.

Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, Toulouse, France.

This study investigates the procedural learning, retention, and reactivation of temporal sensorimotor sequences in children with and without developmental coordination disorder (DCD). Twenty typically-developing (TD) children and 12 children with DCD took part in this study. The children were required to tap on a keyboard, synchronizing with auditory or visual stimuli presented as an isochronous temporal sequence, and practice non-isochronous temporal sequences to memorize them. Read More

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Voluntary control of pelvic frontal rotations in belly dance experts.

Hum Mov Sci 2021 Apr 15;77:102791. Epub 2021 Apr 15.

Université Paris-Saclay, CIAMS, 91405 Orsay, France; Université d'Orléans, CIAMS, 45067 Orléans, France.

The present study investigated how belly dance experts perform the "hip shimmy", a complex rhythmic dance movement consisting in a voluntary oscillation of the pelvis exclusively in the frontal plane with maximised amplitude, with no movement of the upper trunk. The aims of this study were to 1) assess whether the amplitude and stability of the pelvic movement can be maximised in certain postural and frequency conditions; and 2) investigate in a 1 to 3 Hz range whether it is indeed possible to oscillate the pelvis only in the frontal plane and to dissociate this one-axis pelvic rotation from potential spontaneous upper-trunk oscillations. Nineteen belly dance experts performed this task in three frequencies and three knee bending postures. Read More

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A Measure of Concurrent Neural Firing Activity Based on Mutual Information.

Neuroinformatics 2021 Apr 14. Epub 2021 Apr 14.

Department of Engineering, University of Palermo, Palermo, Italy.

Multiple methods have been developed in an attempt to quantify stimulus-induced neural coordination and to understand internal coordination of neuronal responses by examining the synchronization phenomena in neural discharge patterns. In this work we propose a novel approach to estimate the degree of concomitant firing between two neural units, based on a modified form of mutual information (MI) applied to a two-state representation of the firing activity. The binary profile of each single unit unfolds its discharge activity in time by decomposition into the state of neural quiescence/low activity and state of moderate firing/bursting. Read More

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A single stiffened nucleus alters cell dynamics and coherence in a monolayer.

Cytoskeleton (Hoboken) 2021 Apr 9. Epub 2021 Apr 9.

Molecular Biophysics and Structural Biology, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

Force transmission throughout a monolayer is the result of complex interactions between cells. Monolayer adaptation to force imbalances such as singular stiffened cells provides insight into the initiation of disease and fibrosis. Here, NRK-52E cells transfected with ∆50LA, which significantly stiffens the nucleus. Read More

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Cortical maturation from childhood to adolescence is reflected in resting state EEG signal complexity.

Dev Cogn Neurosci 2021 Apr 23;48:100945. Epub 2021 Mar 23.

Department of Psychology, Brock University, St. Catharines, Ontario, Canada.

Endogenous cortical fluctuations captured by electroencephalograms (EEGs) reflect activity in large-scale brain networks that exhibit dynamic patterns over multiple time scales. Developmental changes in the coordination and integration of brain function leads to greater complexity in population level neural dynamics. In this study we examined multiscale entropy, a measure of signal complexity, in resting-state EEGs in a large (N = 405) cross-sectional sample of children and adolescents (9-16 years). Read More

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acquires seconds-scale rhythmic behavior.

J Exp Biol 2021 Apr 1. Epub 2021 Apr 1.

Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-Ku, Sendai, 980-8577, Japan

Detection of the temporal structure of stimuli is crucial for prediction. While perception of interval timing is relevant for immediate behavioral adaptations, it has been scarcely investigated, especially in invertebrates. Here we examined if the fruit fly, , can acquire rhythmic behavior in the range of seconds. Read More

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Monogamy in a Moment: How do Brief Social Interactions Change Over Time in Pair-Bonded Zebra Finches ()?

Integr Org Biol 2020 26;2(1):obaa034. Epub 2020 Dec 26.

Department of Psychology, University of Maryland, College Park, MD, USA.

Research on monogamy has largely focused on marked behaviors that are unique to pair bonded partners. However, these marked behaviors represent only a subset of the pair-directed behaviors that partners engage in; the influence of pair bonding on mundane or subtle social interactions among partners remains largely unknown. In this study, we describe the changes that occur during brief social reunions (or greets) over the course of pair bonding in zebra finches. Read More

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December 2020

High-Pressure O Annealing Enhances the Crystallinity of Ultrawide-Band-Gap Sesquioxides Combined with Graphene for Vacuum-Ultraviolet Photovoltaic Detection.

ACS Appl Mater Interfaces 2021 Apr 31;13(14):16660-16668. Epub 2021 Mar 31.

School of Materials, Sun Yat-sen University, Guangzhou, Guangdong 510275, China.

(AlGa)O is emerging as a promising wide-band-gap sesquioxide for vacuum-ultraviolet (VUV, 10-200 nm) photodetectors and high-power field-effect transistors. However, how the key parameters such as the band gap and crystalline phase of the (AlGa)O-based device vary with stoichiometry has not been explicitly defined, which is due to the unclear underlying mechanism of the Al local coordination environment. In this work, a high-pressure O (20 atm) annealing (HPOA) strategy that can significantly improve the crystallinity of β-(AlGa)O and achieve a tunable optical band gap was proposed, facilitating the revelation of the local structure of Al varying with Al content and the kinetic mechanism of Al diffusion. Read More

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Neuronal oscillations and the mouse prefrontal cortex.

Int Rev Neurobiol 2021 28;158:337-372. Epub 2021 Jan 28.

Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address:

The mouse prefrontal cortex (PFC) encompasses a collection of agranual brain regions in the rostral neocortex and is considered to be critically involved in the neuronal computations underlying intentional behaviors. Flexible behavioral responses demand coordinated integration of sensory inputs with state, goal and memory information in brain-wide neuronal networks. Neuronal oscillations are proposed to provide a temporal scaffold for coordination of neuronal network activity and routing of information. Read More

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January 2021

The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science.

Front Neurol 2021 11;12:631722. Epub 2021 Mar 11.

Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.

Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe. This scenario places unprecedented clinical, social, and economic burden upon patients, families, and health systems. The challenges prove particularly pressing for conditions with highly specific diagnostic and management demands, such as frontotemporal dementia. Read More

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Large- and multi-scale networks in the rodent brain during novelty exploration.

eNeuro 2021 Mar 22. Epub 2021 Mar 22.

Radboud University Medical Center, Donders Centre for Medical Neuroscience.

Neural activity is coordinated across multiple spatial and temporal scales, and these patterns of coordination are implicated in both healthy and impaired cognitive operations. However, empirical cross-scale investigations are relatively infrequent, due to limited data availability and to the difficulty of analyzing rich multivariate datasets. Here we applied frequency-resolved multivariate source-separation analyses to characterize a large-scale dataset comprising spiking and local field potential activity recorded simultaneously in three brain regions (prefrontal cortex, parietal cortex, hippocampus) in freely-moving mice. Read More

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Reaching for known unknowns: Rapid reach decisions accurately reflect the future state of dynamic probabilistic information.

Cortex 2021 May 24;138:253-265. Epub 2021 Feb 24.

Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Canada; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.

Everyday tasks such as catching a ball appear effortless, but in fact require complex interactions and tight temporal coordination between the brain's visual and motor systems. What makes such interceptive actions particularly impressive is the capacity of the brain to account for temporal delays in the central nervous system-a limitation that can be mitigated by making predictions about the environment as well as one's own actions. Here, we wanted to assess how well human participants can plan an upcoming movement based on a dynamic, predictable stimulus that is not the target of action. Read More

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Monitoring of land subsidence due to excessive groundwater extraction using small baseline subset technique in Konya, Turkey.

Osman Orhan

Environ Monit Assess 2021 Mar 10;193(4):174. Epub 2021 Mar 10.

Faculty of Engineering, Department of Geomatics Engineering, Mersin University, 33100, Mersin, Turkey.

Konya, which is located within the Konya Closed Basin, is the most important agricultural production region in Turkey. The future of agriculture is threatened in this region due to the decline in groundwater levels and the intensive agricultural activities that require high water consumption and are not suitable to the climate conditions of the region. In addition to these parameters, the geological structure of Konya also poses various environmental problems such as land subsidence and sinkhole formation. Read More

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Interpersonal autonomic nervous system synchrony and its association to relationship and performance - a systematic review and meta-analysis.

Physiol Behav 2021 Jun 18;235:113391. Epub 2021 Mar 18.

Department of Psychology, Bar-Ilan University, Ramat-Gan, Israel; The Gonda Brain Research Center, Bar Ilan University, Ramat-Gan, Israel. Electronic address:

Interpersonal physiological synchrony is the spontaneous temporal coordination of physiological processes between several individuals. This type of synchrony is critical for human relationships, as it promotes two important outcomes: the quality of the relationships between synchronized individuals, and how well synchronized individuals perform together. Nonetheless a clear estimation of the size of the correlations between interpersonal physiological synchrony and relationship or performance outcomes is missing. Read More

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