243,798 results match your criteria team

How the COVID-19 Pandemic has Changed the Game of Soccer.

Int J Sports Med 2021 Aug 3. Epub 2021 Aug 3.

DFL Sportec Solutions AG, German Professional Soccer League, Munchen, Germany.

This study explores the influence of corona-specific training and playing conditions - especially empty stadiums - on match performance, contact behavior, and home advantage in the Bundesliga (BL) and Bundesliga 2 (BL2). We analyzed the 2017/18, 2018/19, and 2019/20 seasons and compared matches in rounds 26-34 before shutdown with "ghost" matches after restart. Results show increased running activity for high intensity distance: (+ 6. Read More

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Physical Demands and Performance Indicators in Male Professional Cyclists During a Grand Tour: WorldTour Versus ProTeam Category.

Int J Sports Physiol Perform 2021 Aug 3:1-9. Epub 2021 Aug 3.

Purpose: To compare the physical demands and performance indicators of male professional cyclists of 2 different categories (Union Cycliste Internationale WorldTour [WT] and ProTeam [PT]) during a cycling grand tour.

Methods: A WT team (n = 8, 31.4 [5. Read More

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Machine learning directed interventions associate with decreased hospitalization rates in hemodialysis patients.

Int J Med Inform 2021 Jul 24;153:104541. Epub 2021 Jul 24.

Fresenius Medical Care, Global Medical Office, Waltham, United States. Electronic address:

Background: An integrated kidney disease company uses machine learning (ML) models that predict the 12-month risk of an outpatient hemodialysis (HD) patient having multiple hospitalizations to assist with directing personalized interdisciplinary interventions in a Dialysis Hospitalization Reduction Program (DHRP). We investigated the impact of risk directed interventions in the DHRP on clinic-wide hospitalization rates.

Methods: We compared the hospital admission and day rates per-patient-year (ppy) from all hemodialysis patients in 54 DHRP and 54 control clinics identified by propensity score matching at baseline in 2015 and at the end of the pilot in 2018. Read More

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Monitoring sound levels in the intensive care unit: A mixed-methods system development project to optimize design features for a new electronic interface in the healthcare environment.

Int J Med Inform 2021 Jul 22;153:104538. Epub 2021 Jul 22.

Nuffield Department of Clinical Neurosciences, Unhiniversity of Oxford, UK.

Background: Intensive care units (ICU) are busy round the clock and it is difficult to maintain low sound levels that support patient rest. To help ICU staff manage activities we developed a visual display that monitors and reports sound levels in real-time. This facilitates immediate feedback, encouraging proactive behavior change to limit disturbances. Read More

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Team effort: Combinatorial control of seed maturation by transcription factors.

Curr Opin Plant Biol 2021 Jul 31;63:102091. Epub 2021 Jul 31.

Department of Botany, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada. Electronic address:

Seed development is under tight spatiotemporal regulation. Here, we summarize how transcriptional regulation helps shape the major traits during seed maturation, which include storage reserve accumulation, dormancy, desiccation tolerance, and longevity. The regulation is rarely a solo task by an individual transcription factor (TF). Read More

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The Parental Experience of Caring for A Child with Pain and Irritability of Unknown Origin.

J Pain Symptom Manage 2021 Jul 31. Epub 2021 Jul 31.

Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children, Toronto, Canada; University of Toronto, Department of Pediatrics, Toronto, Canada; Division of Pediatric Medicine, Complex Care Program, The Hospital for Sick Children, Toronto, Canada. Electronic address:

Background And Objective: Approximately 73% of children with severe neurological impairment (SNI) can experience episodes of pain and irritability often of unknown origin (PIUO). Limited research exists on how these experiences of PIUO may affect parental caregivers and families. The primary objective of this study was to understand the parental caregiver experience of caring for a child with SNI who experiences persistent PIUO. Read More

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The iPhone, the reflex, and the vinyl record: is the smartphone taking the best intraoperative photographs?

J Vis Commun Med 2021 Aug 3:1-6. Epub 2021 Aug 3.

Department of Surgical Oncology, Aix-Marseille University, CRCM, Marseille, France.

Surgical field photography is a tough exercise: surgeons dedicate the required time for photography even during complex surgeries; the intense lighting of the operating field works against photography, and the surgeon has to utilise whatever equipment is available. We selected five complex interventions and two surgeons (one with an iPhone and one with a Digital Single Lens Reflex [DSLR] camera) who each took a photograph of the operating field. The source of photographs was blinded, and the image quality was scored using a 5-point Likert scale by three groups of team members with differing experiences: six senior surgeons, two junior surgeons, and four surgical residents. Read More

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"Part of a great team": perceptions of geriatrics fellows on doing research during a pandemic.

J Am Geriatr Soc 2021 Aug 3. Epub 2021 Aug 3.

Laboratorio de Investigacao Medica em Envelhecimento (LIM-66), Servico de Geriatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Brazil.

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Individualized Education Program Team Members' Perceptions of Music Therapy: An Interpretivist Investigation.

J Music Ther 2021 Aug 3. Epub 2021 Aug 3.

University of Minnesota, Minneapolis, MN, USA.

Although music therapists are often members of the Individualized Education Program (IEP) team in educational settings, there is a lack of research exploring IEP members' perceptions of music therapy. The purpose of this interpretivist study was to understand the perceptions IEP team members have of music therapy in educational settings; 8 professionals from a single school district who had experience working with music therapists as part of the IEP team participated in an individual semi-structured interview. We used in-vivo coding, an inductive approach to thematic analysis, and member and peer checking. Read More

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Cannabis-Related Perceptions as Mediators of the Association Between Trait Impulsivity and Cannabis Outcomes.

J Stud Alcohol Drugs 2021 Jul;82(4):522-535

Universidad Nacional de Córdoba, Facultad de Psicología, Córdoba, Argentina.

Objective: Normative perceptions have been shown to mediate the effect of personality traits on cannabis outcomes. We examined descriptive norms, injunctive norms, and the role of cannabis in college life as possible mediators of the association between impulsivity-related traits (i.e. Read More

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Efficient Blue Light Emitting Diodes Based On Europium Halide Perovskites.

Adv Mater 2021 Aug 3:e2101903. Epub 2021 Aug 3.

Wuhan National Laboratory for Optoelectronics (WNLO) and School of Optical and Electronic Information, Huazhong University of Science and Technology (HUST), 1037 Luoyu Road, Wuhan, Hubei, 430074, China.

Flat panel displays enjoy 100 billion-dollar markets with significant penetration in daily life, which require efficient, color-saturated blue, green, and red light-emitting diodes (LEDs). The recently emerged halide perovskites have demonstrated low-cost and outstanding performance for potential LED applications. However, the performance of blue perovskite LEDs (PeLEDs) lags far behind red and green cousins, particularly for color coordinates approaching (0. Read More

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Key Roles of RGD-Recognizing Integrins During Cardiac Development, on Cardiac Cells, and After Myocardial Infarction.

J Cardiovasc Transl Res 2021 Aug 3. Epub 2021 Aug 3.

Centre de Recherche Clinique, Grand Hôpital de l'Est Francilien, Meaux, France.

Cardiac cells interact with the extracellular matrix (ECM) proteins through integrin mechanoreceptors that control many cellular events such as cell survival, apoptosis, differentiation, migration, and proliferation. Integrins play a crucial role in cardiac development as well as in cardiac fibrosis and hypertrophy. Integrins recognize oligopeptides present on ECM proteins and are involved in three main types of interaction, namely with collagen, laminin, and the oligopeptide RGD (Arg-Gly-Asp) present on vitronectin and fibronectin proteins. Read More

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Residential greenness attenuated associations of long-term exposure to air pollution with biomarkers of advanced fibrosis.

Environ Sci Pollut Res Int 2021 Aug 3. Epub 2021 Aug 3.

Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, 450001, People's Republic of China.

Long-term exposure to air pollutants and residential greenness related to advanced fibrosis have been sparsely studied in low- and middle-income countries. A total of 29883 participants were selected from a cross-sectional survey of the Henan Rural Cohort. Concentrations of air pollutants (particulate matter with an aerodynamic diameter ≤ 1. Read More

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Weaving Lines of Inquiry: Promoting Transdisciplinarity as a Distinctive Way of Undertaking Sport Science Research.

Sports Med Open 2021 Aug 3;7(1):55. Epub 2021 Aug 3.

Sport & Human Performance Research Group, Sheffield Hallam University, Sheffield, UK.

The promotion of inter- and multidisciplinarity - broadly drawing on other disciplines to help collaboratively answer important questions to the field - has been an important goal for many professional development organisations, universities, and research institutes in sport science. While welcoming collaboration, this opinion piece discusses the value of transdisciplinary research for sports science. The reason for this is that inter- and multidisciplinary research are still bound by disciplinary convention - often leading sport science researchers to study about a phenomenon based on pre-determined disciplinary ways of conceptualising, measuring, and doing. Read More

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"Clinical Teachers: Teaching Tips for the Busy Veterinary Team": Reflections on the Development of a Multimodal Resource for Veterinarians and Veterinary Nurses / Technologists New to Clinical Teaching.

J Vet Med Educ 2021 Aug 2:e20200147. Epub 2021 Aug 2.

Clinical practice-based training/work-integrated learning (WIL) is an applied, social, and high-impact element of the veterinary curriculum. Within this context, students are learning "on the job" with clinician-educators who are carrying out their professional duties at the same time as supporting learning. To equip clinician-educators with role awareness and general teaching skills, it is recommended that all have access to basic teacher training. Read More

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The contribution of family physicians to residential mental health care during the COVID-19 pandemic in Tshwane District, South Africa.

Afr J Prim Health Care Fam Med 2021 Jul 23;13(1):e1-e3. Epub 2021 Jul 23.

Department of Family Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria.

During the start of the first wave of the coronavirus disease 2019 (COVID-19) pandemic, two family physicians in Tshwane, South Africa, reviewed the people at high-risk within their Health Catchment Area. The largest residential mental health care facility in Gauteng fell under their care, and they were responsible for providing care and support to this facility. Family physicians have to lead the primary care team and simultaneously take care of the well-being of their team members. Read More

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Policy and planning for large epidemics and pandemics - challenges and lessons learned from COVID-19.

Curr Opin Infect Dis 2021 Aug 2. Epub 2021 Aug 2.

UK Public Health Rapid Support Team, Public Health England/London School of Hygiene & Tropical Medicine Institute for Global Health, University College London, London, UK Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.

Purpose Of Review: The COVID-19 pandemic is a global catastrophe that has led to untold suffering and death. Many previously identified policy challenges in planning for large epidemics and pandemics have been brought to the fore, and new ones have emerged. Here, we review key policy challenges and lessons learned from the COVID-19 pandemic in order to be better prepared for the future. Read More

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A Parsimonious Prognostic Model and Heat Map for Predicting Survival Following Adjuvant Radiotherapy in Parotid Gland Carcinoma With Lymph Node Metastasis.

Technol Cancer Res Treat 2021 Jan-Dec;20:15330338211035257

Department of Head and Neck surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.

Objectives: To construct a simplified prognostic risk model to predict overall survival after adjuvant radiotherapy for parotid gland carcinoma patients with stage T1-4aN1-3M0.

Materials And Methods: We evaluated 879 patients who were pathological diagnosed as stage T1-4aN1-3M0 parotid gland cancer. Those eligible patients treated with parotidectomy and neck lymph node dissection between 2004 and 2015 in the Surveillance Epidemiology and End Results database. Read More

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Detection of expanded-spectrum cephalosporin hydrolysis by lateral flow immunoassay.

Microb Biotechnol 2021 Aug 2. Epub 2021 Aug 2.

Département Médicaments et Technologies pour la Santé (DMTS), SPI, Université Paris-Saclay, CEA, INRAE, Gif-sur-Yvette, 91191, France.

Early detection of expanded-spectrum cephalosporin (ESC) resistance is essential not only for an effective therapy but also for the prompt implementation of infection control measures to prevent dissemination in the hospital. We have developed and validated a lateral flow immunoassay (LFIA), called LFIA-CTX test, for the detection of ESC (cefotaxime) hydrolytic activity based on structural discrimination between the intact antibiotic and its hydrolysed product. A single bacterial colony was suspended in an extraction buffer containing cefotaxime. Read More

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Editor Profile: Brent Derry.

Brent Derry

FEBS J 2021 Aug;288(15):4435-4438

The FEBS Journal Editorial Office, Cambridge, UK.

In this special interview series, we profile members of The FEBS Journal editorial board to highlight their research focus and perspectives on the journal and future directions in their field. Brent Derry is Professor at the Department of Molecular Genetics of University of Toronto and Senior Scientist of the Developmental & Stem Cell Biology Program at The Hospital for Sick Children (Toronto, Canada). He has served as an editorial board member of The FEBS Journal since 2017. Read More

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Editor Profile: Angela Gronenborn.

FEBS J 2021 Aug;288(15):4432-4434

Department of Structural Biology, University of Pittsburgh School of Medicine, PA, USA.

In this special interview series, we profile members of The FEBS Journal editorial board to highlight their research focus, perspectives on the journal and future directions in their field and beyond. Angela M. Gronenborn is the UPMC Rosalind Franklin Professor and Chair of the Department of Structural Biology, University of Pittsburgh, School of Medicine and Professor of Bioengineering, Swanson School of Engineering, Pittsburgh, USA. Read More

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Editor Profile: Nikos Karamanos.

FEBS J 2021 Aug;288(15):4442-4444

Department of Chemistry, University of Patras, Greece.

In this special interview series, we profile members of The FEBS Journal editorial board to highlight their research focus, perspectives on the journal and future directions in their field. Nikos Karamanos is Professor of Biochemistry in the Department of Chemistry, University of Patras in Greece. He joined the editorial board of The FEBS Journal in 2020, having previously served on the advisory board for several years. Read More

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Convergent epitope-specific T cell responses after SARS-CoV-2 infection and vaccination.

medRxiv 2021 Jul 27. Epub 2021 Jul 27.

SARS-CoV-2 mRNA vaccines, including Pfizer/Biontech BNT162b2, were shown to be effective for COVID-19 prevention, eliciting both robust antibody responses in naive individuals and boosting pre-existing antibody levels in SARS-CoV-2-recovered individuals. However, the magnitude, repertoire, and phenotype of epitope-specific T cell responses to this vaccine, and the effect of vaccination on pre-existing T cell memory in SARS-CoV-2 convalescent patients, are still poorly understood. Thus, in this study we compared epitope-specific T cells elicited after natural SARS-CoV-2 infection, and vaccination of both naive and recovered individuals. Read More

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Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation.

Res Sq 2021 Jul 27. Epub 2021 Jul 27.

The microbial populations in the gut microbiome have recently been associated with COVID-19 disease severity. However, a causal impact of the gut microbiome on COVID-19 patient health has not been established. Here we provide evidence that gut microbiome dysbiosis is associated with translocation of bacteria into the blood during COVID-19, causing life-threatening secondary infections. Read More

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Doses delivered by portal imaging quality assurance in routine practice of adjuvant breast radiotherapy worth to by monitored and compensated in some cases.

Quant Imaging Med Surg 2021 Aug;11(8):3481-3493

Department of Cancerology-Radiotherapy, University Hospital Grenoble-Alpes, Grenoble, France.

Background: Imaging, in radiotherapy, has become a routine tool for repositioning of the target volume at each session. The repositioning precision, currently infracentimetric, evolves along with the irradiation techniques. This retrospective study aimed to identify practices and doses resulting from the use of high energy planar imaging (portal imaging) in daily practice. Read More

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Engineered models of the human embryo.

Nat Biotechnol 2021 Aug 2. Epub 2021 Aug 2.

Ghent Fertility and Stem cell Team (G-FaST), Department for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium.

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The role of epigenetic modifications, long-range contacts, enhancers and topologically associating domains in the regulation of glioma grade-specific genes.

Sci Rep 2021 Aug 2;11(1):15668. Epub 2021 Aug 2.

Institute of Computer Science of the Polish Academy of Sciences, Warsaw, Poland.

Genome-wide studies have uncovered specific genetic alterations, transcriptomic patterns and epigenetic profiles associated with different glioma types. We have recently created a unique atlas encompassing genome-wide profiles of open chromatin, histone H3K27ac and H3Kme3 modifications, DNA methylation and transcriptomes of 33 glioma samples of different grades. Here, we intersected genome-wide atlas data with topologically associating domains (TADs) and demonstrated that the chromatin organization and epigenetic landscape of enhancers have a strong impact on genes differentially expressed in WHO low grade versus high grade gliomas. Read More

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Simulation of solute transport behaviors in saturated karst aquifer system.

Sci Rep 2021 Aug 2;11(1):15614. Epub 2021 Aug 2.

Non-Ferrous Metals and Nuclear Industry Geological Exploration Bureau Geophysical and Geochemical Exploration Team of Guizhou, Duyun, 558000, China.

The karst development makes aquifer have strong anisotropy and heterogeneity. In order to reveal the characteristics of solute transport in the karst fissure-conduit aquifer system, this study presents a physical model of fissure-conduit in laboratory experiments to carry out the solute transport simulation. In this paper, the tracer tests of fissure-conduit combination, fissure, and conduit solute transport process in saturated flow are designed. Read More

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Bringing specialist paediatric surgical care to the doorstep in rural Ghana: A mobile paediatric surgery clinic.

Afr J Paediatr Surg 2021 Oct-Dec;18(4):195-200

Department of Surgery, Gye Nyame Mobile Clinic Affiliated to St. Patrick's Missionary Hospital; Department of Surgery, St. Patrick's Missionary Hospital, Maase- Offinso, Ghana.

Background: The contribution of paediatric surgical conditions to the total burden of disease in low- and middle-income countries (LMICs) has recently been highlighted and it is widely agreed that solutions are needed to provide access to safe and affordable surgery for these children.

Materials And Methods: We present a simple, cost-effective model that brings paediatric surgery to the doorstep of remote areas and uses the existing health system structure in its entity to fulfil patients' needs. Mobile clinic teams whose members are integrated staff in affiliated mission hospitals reach out daily on a rotational basis to 10 health posts. Read More

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