Exp Ther Med 2020 Apr 21;19(4):2913-2922. Epub 2020 Feb 21.
Department of Cardiothoracic Surgery, Zhuji People's Hospital, Zhuji, Zhejiang 311800, P.R. China.
The efficacy of ginsenoside Rh2 (Rh2) in cancer therapy has been reported; however, its function in lung cancer remains unknown. To analyze the role of Rh2 in the inhibition of lung cancer cell proliferation in the present study, protein expression levels of E-cadherin, vimentin, β-catenin, Smo, Gli1, and α-catenin were assessed by western blotting, whilst mRNA expression levels of , , , , and were determined by reverse transcription-quantitative PCR in the A549 cell line. Phosphorylation sites were detected by proteomic methods and cell proliferation was analyzed by MTT assay. Read More