J Hazard Mater 2021 Jun 11;418:126387. Epub 2021 Jun 11.
Nireas-International Water Research Centre, University of Cyprus, P.O. Box 20537, Nicosia, CY 1678, Cyprus; Department of Civil and Environmental Engineering, University of Cyprus, P.O. Box 20537, Nicosia, CY 1678, Cyprus. Electronic address:
The conventional activated sludge (CAS) process has limited capacity to remove pathogenic microorganisms and antibiotic resistance genes (ARGs), compared to membrane bioreactors (MBRs). However, the full extent of pathogenic microbial fraction, resistome (antibiotic and biocide resistance genes, ARGs and BRGs) and mobilome (mobile genetic elements, MGE) of urban wastewater treatment plant (UWTP) influents and effluents remains unknown. Thus, the fate of putative pathogenic bacteria, ARGs and potential co-occurrence patterns with BRGs, MGEs and bacterial-predatory microorganisms was determined in two full-scale UWTPs, a MBR and a CAS system, using shotgun metagenomics. Read More