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End-to-end keyword search system based on attention mechanism and energy scorer for low resource languages.

Neural Netw 2021 Apr 10;139:326-334. Epub 2021 Apr 10.

Beijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Tsinghua University, Beijing 100084, China. Electronic address:

Keyword search (KWS) means searching for keywords given by the user from continuous speech. Conventional KWS systems are based on Automatic Speech Recognition (ASR), where the input speech has to be first processed by the ASR system before keyword searching. In the recent decade, as deep learning and deep neural networks (DNN) become increasingly popular, KWS systems can also be trained in an end-to-end (E2E) manner. Read More

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Atmospheric nitrogen deposition: A review of quantification methods and its spatial pattern derived from the global monitoring networks.

Ecotoxicol Environ Saf 2021 Apr 14;216:112180. Epub 2021 Apr 14.

College of Resources and Environmental Sciences; National Academy of Agriculture Green Development; Key Laboratory of Plant-Soil Interactions of MOE, China Agricultural University, Beijing 100193, China.

Atmospheric nitrogen (N) deposition is a vital component of the global N cycle. Excessive N deposition on the Earth's surface has adverse impacts on ecosystems and humans. Quantification of atmospheric N deposition is indispensable for assessing and addressing N deposition-induced environmental issues. Read More

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Reduced spatial resolution MRI suffices to image and quantify drought induced embolism formation in trees.

Plant Methods 2021 Apr 6;17(1):38. Epub 2021 Apr 6.

IBG-2: Plant Sciences, Forschungszentrum Jülich, Jülich, Germany.

Background: Magnetic resonance imaging (MRI) is uniquely suited to non-invasively and continuously monitor embolism formation in trees. Depending on the MRI method used, quantitative parameter maps of water content and MRI signal relaxation behavior can be generated. The ability to measure dynamic differences in water content and relaxation behavior can be used to detect xylem embolism formation, even if xylem conduits are too small to be spatially resolved. Read More

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Equilibrial service composition model in Cloud manufacturing (ESCM) based on non-cooperative and cooperative game theory for healthcare service equipping.

PeerJ Comput Sci 2021 1;7:e410. Epub 2021 Mar 1.

School of Industrial Engineering, South Tehran Branch, Islamic Azad University, Tehran, Tehran, Iran.

Industry 4.0 is the digitalization of the manufacturing systems based on Information and Communication Technologies (ICT) for developing a manufacturing system to gain efficiency and improve productivity. Cloud Manufacturing (CM) is a paradigm of Industry 4. Read More

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Influence of tweets and diversification on serendipitous research paper recommender systems.

PeerJ Comput Sci 2020 18;6:e273. Epub 2020 May 18.

University of Essex, Colchester, UK.

In recent years, a large body of literature has accumulated around the topic of research paper recommender systems. However, since most studies have focused on the variable of accuracy, they have overlooked the serendipity of recommendations, which is an important determinant of user satisfaction. Serendipity is concerned with the relevance and unexpectedness of recommendations, and so serendipitous items are considered those which positively surprise users. Read More

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The New Trend of State Estimation: From Model-Driven to Hybrid-Driven Methods.

Sensors (Basel) 2021 Mar 16;21(6). Epub 2021 Mar 16.

Artificial Intelligence College, Beijing Technology and Business University, Beijing 100048, China.

State estimation is widely used in various automated systems, including IoT systems, unmanned systems, robots, etc. In traditional state estimation, measurement data are instantaneous and processed in real time. With modern systems' development, sensors can obtain more and more signals and store them. Read More

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Characteristics of Onefold Clocks of GPS, Galileo, BeiDou and GLONASS Systems.

Sensors (Basel) 2021 Mar 30;21(7). Epub 2021 Mar 30.

Department of Geotechnical Engineering, Faculty of Civil Engineering and Architecture, Lublin University of Technology, 20-618 Lublin, Poland.

This research is focused on searching for frequency and noise characteristics for available GNSS (Global Navigation Satellite Systems). The authors illustrated frequency stability and noise characteristics for a selected set of data from four different GNSS systems. For this purpose, 30-s-interval clock corrections were used for the GPS weeks 1982-2034 (the entirety of 2018). Read More

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Novel Transfer Learning Approach for Medical Imaging with Limited Labeled Data.

Cancers (Basel) 2021 Mar 30;13(7). Epub 2021 Mar 30.

Faculty of Electrical Engineering & Computer Science, University of Missouri, Columbia, MO 65211, USA.

Deep learning requires a large amount of data to perform well. However, the field of medical image analysis suffers from a lack of sufficient data for training deep learning models. Moreover, medical images require manual labeling, usually provided by human annotators coming from various backgrounds. Read More

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A Structural Entropy Measurement Principle of Propositional Formulas in Conjunctive Normal Form.

Entropy (Basel) 2021 Mar 4;23(3). Epub 2021 Mar 4.

Key Laboratory of Complex Systems and Intelligent Computing and School of Mathematics and Statistics, Qiannan Normal University for Nationalities, Duyun 558000, China.

The satisfiability (SAT) problem is a core problem in computer science. Existing studies have shown that most industrial SAT instances can be effectively solved by modern SAT solvers while random SAT instances cannot. It is believed that the structural characteristics of different SAT formula classes are the reasons behind this difference. Read More

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Traffic Signal Control Using Hybrid Action Space Deep Reinforcement Learning.

Sensors (Basel) 2021 Mar 25;21(7). Epub 2021 Mar 25.

École de Technologie Supérieure, University of Quebec, Montreal, QC H3C 1K3, Canada.

Recent research works on intelligent traffic signal control (TSC) have been mainly focused on leveraging deep reinforcement learning (DRL) due to its proven capability and performance. DRL-based traffic signal control frameworks belong to either discrete or continuous controls. In discrete control, the DRL agent selects the appropriate traffic light phase from a finite set of phases. Read More

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Comparative Assessment of Tubular Ceramic, Spiral Wound, and Hollow Fiber Membrane Microfiltration Module Systems for Milk Protein Fractionation.

Foods 2021 Mar 24;10(4). Epub 2021 Mar 24.

Chair of Food and Bioprocess Engineering, TUM School of Life Sciences, Technical University of Munich, Weihenstephaner Berg 1, 85354 Freising, Germany.

The fractionation efficiency of hollow fiber membranes (HFM) for milk protein fractionation was compared to ceramic tubular membranes (CTM) and spiral wound membranes (SWM). HFM combine the features of high membrane packing density of SWM and the more defined flow conditions and better control of membrane fouling in the open flow channel cross-sections of CTM. The aim was to comparatively analyze the effect of variations in local pressure and flow conditions while using single industrially sized standard modules with similar dimensions and module footprints (module diameter and length). Read More

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Treatment of Manure and Digestate Liquid Fractions Using Membranes: Opportunities and Challenges.

Int J Environ Res Public Health 2021 Mar 17;18(6). Epub 2021 Mar 17.

Department of Green Technology, Faculty of Engineering, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.

Manure and digestate liquid fractions are nutrient-rich effluents that can be fractionated and concentrated using membranes. However, these membranes tend to foul due to organic matter, solids, colloids, and inorganic compounds including calcium, ammonium, sodium, sulfur, potassium, phosphorus, and magnesium contained in the feed. This review paper is intended as a theoretical and practical tool for the decision-making process during design of membrane-based systems aiming at processing manure liquid fractions. Read More

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Effect of Fluence and Multi-Pass on Groove Morphology and Process Efficiency of Laser Structuring for 3D Electrodes of Lithium-Ion Batteries.

Materials (Basel) 2021 Mar 8;14(5). Epub 2021 Mar 8.

Department of Future Convergence Engineering, Graduate School, Kongju National University, Cheonan 1223-24, Korea.

Lithium-ion batteries (LIBs) are widely used as energy storage systems. With the growing interest in electric vehicles, battery performance related to traveling distance has become more important. Therefore, there are various studies going on to achieve high-power and high-energy batteries. Read More

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A Privacy-Preserving Cross-Domain Healthcare Wearables Recommendation Algorithm Based on Domain-Dependent and Domain-Independent Feature Fusion.

IEEE J Biomed Health Inform 2021 Apr 1;PP. Epub 2021 Apr 1.

Recently, recommender systems are applied to provide personalized recomendation for healthcare wearables. However, due to the sparsity problem, traditional recommendation algorithms are difficult to achieve desired performance. Considering that consumers often buy and rate other types of items on E-commerce platforms, we can leverage significant information in the auxiliary domains to improve the recommendation performance of healthcare wearables, which can be regarded as cross-domain recommendation. Read More

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The role of enhanced plantar-surface sensory feedback on lower limb EMG during planned gait termination.

Somatosens Mot Res 2021 Mar 31:1-11. Epub 2021 Mar 31.

Department of Kinesiology and Physical Education, Faculty of Science, Wilfrid Laurier University, Waterloo, ON, Canada.

Purpose/aim of the study: Generation of smooth movement relies on the central nervous system (CNS) having information from the visual, vestibular and somatosensory systems to effectively execute motor behaviour. Recently, cutaneous afferent inputs have been linked to lower leg motorneuron pools, resulting in a growing interest of adding texture to the plantar foot sole interface as a novel method to facilitate cutaneous feedback. The aim of this study was to characterize the changes in magnitude and temporal organization of muscle activity, and to investigate motor output changes from enhanced tactile feedback during perturbed gait termination. Read More

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An //1 queue with workload-dependent processing speed and vacations.

Queueing Syst 2021 Mar 25:1-33. Epub 2021 Mar 25.

Department of Policy and Planning Sciences, Faculty of Engineering, Information and Systems, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573 Japan.

Motivated by the trade-off issue between delay performance and energy consumption in modern computer and communication systems, we consider a single-server queue with phase-type service requirements and with the following two special features: Firstly, the service speed is a piecewise constant function of the workload. Secondly, the server switches off when the system becomes empty, only to be activated again when the workload reaches a certain threshold. For this system, we obtain the steady-state workload distribution and its moments of any order. Read More

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A feasibility study on microwave imaging of bone for osteoporosis monitoring.

Med Biol Eng Comput 2021 Apr 30;59(4):925-936. Epub 2021 Mar 30.

Electrical and Electronic Engineering, National University of Ireland Galway, Galway, Ireland.

The dielectric properties of bones are found to be influenced by the demineralisation of bones. Therefore, microwave imaging (MWI) can be used to monitor in vivo dielectric properties of human bones and hence aid in the monitoring of osteoporosis. This paper presents the feasibility analysis of the MWI device for monitoring osteoporosis. Read More

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Effective degradation of EGFR mutant proteins by CRBN-based PROTACs through both proteosome and autophagy/lysosome degradation systems.

Eur J Med Chem 2021 Mar 7;218:113328. Epub 2021 Mar 7.

Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China. Electronic address:

Targeted therapy of treating patients with specific tyrosine kinase inhibitors (TKIs) is currently the standard care for epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer. However, the inevitably developed drug resistance in patients to EGFR TKIs is the biggest obstacle for cancer targeted therapy. About 60% of drug resistance to the 1st generation of EGFR TKIs was resulted from an acquired T790M mutation in the kinase domain of EGFR protein. Read More

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Setting research priorities for sexual, reproductive, maternal, newborn, child and adolescent health in humanitarian settings.

Confl Health 2021 Mar 26;15(1):16. Epub 2021 Mar 26.

Center for Child Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Background: An estimated 70.8 million people are forcibly displaced worldwide, 75% of whom are women and children. Prioritizing a global research agenda to inform guidance, service delivery, access to and quality of services is essential to improve the survival and health of women, children and adolescents in humanitarian settings. Read More

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Method-oriented systematic review on the simple scale for acceptance measurement in advanced transport telematics.

PLoS One 2021 25;16(3):e0248107. Epub 2021 Mar 25.

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Sociology and Rehabilitation Science, Berlin, Germany.

Acceptance intuitively is a precondition for the adaptation and use of technology. In this systematic review, we examine academic literature on the "simple scale for acceptance measurement" provided by Van der Laan, Heino, and de Waard (1997). This measure is increasingly applied in research on mobility systems without having been thoroughly analysed. Read More

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Health research knowledge translation into policy in Zambia: policy-maker and researcher perspectives.

Health Res Policy Syst 2021 Mar 24;19(1):42. Epub 2021 Mar 24.

Department of Health Policy and Management, School of Public Health, University of Zambia, P.O. Box 51110, Lusaka, Zambia.

Background: The translation of public health research evidence into policy is critical to strengthening the capacity of local health systems to respond to major health challenges. However, a limited amount of public health research evidence generated in developing countries is actually translated into policy because of various factors. This study sought to explore the process of health research knowledge translation into policy and to identify factors that facilitate or hinder the process in Zambia. Read More

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Medical care in Australian residential aged care: Perspectives of residents, family, nurses and general practitioners.

Health Soc Care Community 2021 Mar 24. Epub 2021 Mar 24.

Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia.

The importance of residential aged care facility (RACF)'s medical care is growing, driven by world-wide demographic trends in ageing populations. Despite this, there is a paucity of research into this care delivery from the perspective of those most involved. This study aimed to identify the enablers of and barriers to satisfactory RACF medical care by focusing on the general practitioner (GP) visit in the experience of residents, their family, registered nurses (RNs) and GPs. Read More

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A Recommendation Approach for Rating Prediction Based on User Interest and Trust Value.

Comput Intell Neurosci 2021 6;2021:6677920. Epub 2021 Mar 6.

Department of Computer Science and Technology, Harbin University of Science and Technology, Harbin, Heilongjiang 150000, China.

Collaborative filtering recommendation algorithm is one of the most researched and widely used recommendation algorithms in personalized recommendation systems. Aiming at the problem of data sparsity existing in the traditional collaborative filtering recommendation algorithm, which leads to inaccurate recommendation accuracy and low recommendation efficiency, an improved collaborative filtering algorithm is proposed in this paper. The algorithm is improved in the following three aspects: firstly, considering that the traditional scoring similarity calculation excessively relies on the common scoring items, the Bhattacharyya similarity calculation is introduced into the traditional calculation formula; secondly, the trust weight is added to accurately calculate the direct trust value and the trust transfer mechanism is introduced to calculate the indirect trust value between users; finally, the user similarity and user trust are integrated, and the prediction result is generated by the trust weighting method. Read More

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Laboratory observations for two-dimensional solute transport in an aquifer-aquitard system.

Environ Sci Pollut Res Int 2021 Mar 18. Epub 2021 Mar 18.

School of Environmental Studies, China University of Geosciences, NO. 68 Jincheng Street, East Lake High-Tech, 17 Development Zone, Wuhan, Hubei, 430074, People's Republic of China.

Low-permeability media such as clay appear in nearly all hydrogeological systems. To date, although significant efforts have been put forward by hydrologists, transport mechanism is still not well understood in such media, especially in an aquifer-aquitard system. In this study, two-dimensional experiments of groundwater flow and solute transport were conducted in a clay-sand two-layer system to investigate the characteristics of flow and transport in such a system. Read More

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Collective predator evasion: Putting the criticality hypothesis to the test.

PLoS Comput Biol 2021 Mar 15;17(3):e1008832. Epub 2021 Mar 15.

Department of Biology, Institute for Theoretical Biology, Humboldt-Universität zu Berlin, Berlin, Germany.

According to the criticality hypothesis, collective biological systems should operate in a special parameter region, close to so-called critical points, where the collective behavior undergoes a qualitative change between different dynamical regimes. Critical systems exhibit unique properties, which may benefit collective information processing such as maximal responsiveness to external stimuli. Besides neuronal and gene-regulatory networks, recent empirical data suggests that also animal collectives may be examples of self-organized critical systems. Read More

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A global profiling strategy using comprehensive two-dimensional liquid chromatography coupled with dual-mass spectrometry platforms: Chemical analysis of a multi-herb Chinese medicine formula as a case study.

J Chromatogr A 2021 Apr 27;1642:462021. Epub 2021 Feb 27.

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. Electronic address:

Although ultraviolet detector or mass spectrometer could be coupled with two-dimensional liquid chromatography (2DLC) to analyze complex constituents, full detection and identification of the compounds are difficult. Suffering from biased UV detection and insufficient MS data interpretation, a number of minor compounds are neglected though they are separated. In this study, we report a global chemical profiling strategy using comprehensive 2DLC coupled with dual-MS platforms, including Orbitrap-MS and QqQ-MS. Read More

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Predicting future cognitive decline with hyperbolic stochastic coding.

Med Image Anal 2021 May 24;70:102009. Epub 2021 Feb 24.

School of Computing, Informatics, and Decision Systems Engineering, Arizona State University, Tempe, AZ, 85287 USA. Electronic address:

Hyperbolic geometry has been successfully applied in modeling brain cortical and subcortical surfaces with general topological structures. However, such approaches, similar to other surface-based brain morphology analysis methods, usually generate high dimensional features. It limits their statistical power in cognitive decline prediction research, especially in datasets with limited subject numbers. Read More

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Heart transplantation: the Berlin experience and perspectives.

Cardiovasc Diagn Ther 2021 Feb;11(1):243-253

Cardio Centrum Berlin, Berlin, Germany.

In patients with end-stage heart failure, heart transplants are now an ingrained practice, as they provide satisfying long-term results with good predictability and quality of life. The successful outcome has evolved from the development of effective immunosuppression, recognition of allograft rejection through diagnostic modalities and improvement in donor organ perfusion. Unfortunately, transplant availability is constrained by the shortage of donor organs and is therefore considered a casuistic therapy. Read More

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February 2021

Subgroup Invariant Perturbation for Unbiased Pre-Trained Model Prediction.

Front Big Data 2020 18;3:590296. Epub 2021 Feb 18.

Department of Computer Science and Engineering, Indian Institute of Technology Jodhpur, Rajasthan, India.

Modern deep learning systems have achieved unparalleled success and several applications have significantly benefited due to these technological advancements. However, these systems have also shown vulnerabilities with strong implications on the fairness and trustability of such systems. Among these vulnerabilities, bias has been an . Read More

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February 2021

Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration.

PLoS Comput Biol 2021 Mar 10;17(3):e1008213. Epub 2021 Mar 10.

Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom.

Cell migration in 3D microenvironments is a complex process which depends on the coordinated activity of leading edge protrusive force and rear retraction in a push-pull mechanism. While the potentiation of protrusions has been widely studied, the precise signalling and mechanical events that lead to retraction of the cell rear are much less well understood, particularly in physiological 3D extra-cellular matrix (ECM). We previously discovered that rear retraction in fast moving cells is a highly dynamic process involving the precise spatiotemporal interplay of mechanosensing by caveolae and signalling through RhoA. Read More

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