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Ten-year Thyroid Cancer Incidence in an Integrated Healthcare Delivery System.

Perm J 2021 May;25

Department of Medicine, Kaiser Permanente Oakland Medical Center, Oakland, CA.

Introduction: The incidence of papillary thyroid cancer (PTC) has increased in recent decades, but data from community-based settings are limited. This study characterizes PTC trends in a large, integrated healthcare system over 10 years.

Methods: The annual incidence of PTC (2006-2015) was examined among Kaiser Permanente Northern California adults aged 21 to 84 years using Cancer Registry data, including tumor size and stage. Read More

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Contrastive Study of the Foaming Properties of N-Acyl Amino Acid Surfactants with Bovine Serum Albumin and Gelatin.

J Oleo Sci 2021 May 7. Epub 2021 May 7.

Beijing Engineering and Technology Research Center of Food Additives, Beijing Higher Institution Engineering Research Center of Food Additives and Ingredients, Beijing Technology and Business University.

A detailed study on the foamability, foam stability, foam liquid-carrying capacity, and foam morphology of two N-acyl amino acid surfactants with bovine serum albumin (BSA) and gelatin were performed by foam scanning. The results showed that the foamability of the mixed system increased gradually and then tended to be stable with increasing surfactant concentration. The foamability of the high-concentration BSA system was stronger than that of the low-concentration BSA system. Read More

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Rural and racial disparities in colorectal cancer incidence and mortality in South Carolina, 1996 - 2016.

J Rural Health 2021 May 8. Epub 2021 May 8.

Department of Epidemiology & Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA.

Purpose: Colorectal cancer (CRC) is the third leading cause of cancer mortality among men and women in the United States and South Carolina (SC). Since SC has one of the highest proportions of Black (27.9%) and rural residents (33. Read More

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Vertical diversity and association pattern of total, abundant and rare microbial communities in deep-sea sediments.

Mol Ecol 2021 May 7. Epub 2021 May 7.

College of Marine Life Sciences, and Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, 266003, China.

Microbial abundance and community composition in marine sediments have been widely explored. However, high-resolution vertical changes of benthic microbial diversity and co-occurrence patterns are poorly described. The ecological contributions of abundant and rare species in sediments also remain largely unknown. Read More

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Real-World Patient Experience of Long-Term Hybrid Closed-Loop Insulin Pump Use.

Can J Diabetes 2021 Mar 2. Epub 2021 Mar 2.

Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ontario, Canada; Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

Objectives: Understanding of patient experiences and adaptations to hybrid closed-loop (HCL) pumps beyond the confines of short-term clinical trials is needed to inform best practices surrounding this emerging technology. We investigated long-term, real-world patient experiences with HCL technology.

Methods: In semistructured interviews, 21 adults with type 1 diabetes at a single Canadian tertiary diabetes centre discussed their transition to use of Medtronic MiniMed 670G auto-mode. Read More

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Incorporation of Patient-Reported Outcomes Measurement Information System to assess quality of life among patients with breast cancer initiating care at an academic center.

Cancer 2021 May 6. Epub 2021 May 6.

University of California San Francisco, San Francisco, California.

Background: Symptom burden and reduced quality of life (QOL) are considerable hurdles in oncology. The authors used the Patient-Reported Outcomes Measurement Information System (PROMIS), which assesses physical and psychosocial health, to establish a mean symptom burden, examine potential drivers, and characterize severe symptom burden in breast cancer patient subgroups with the goal of characterizing stage IV patient QOL and triaging patients to individualized supportive care services.

Methods: New patients at the University of California San Francisco Breast Care Center received questionnaires with 8 PROMIS domains: depression, anxiety, fatigue, sleep-related impairment, sleep disturbance, cognitive function, cognitive abilities, and physical function. Read More

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Convergence of the turkey gut microbiota following cohabitation under commercial settings.

J Anim Sci Biotechnol 2021 May 5;12(1):59. Epub 2021 May 5.

Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, MN, USA.

Background: Microbiota development is a critical aspect of turkey poult maturation, and the succession of microbes in the turkey gut has been shown to correlate with poult performance. The purpose of this study was to determine the fate of the microbiota in turkey poults after movement of birds first raised in an isolated hatch brood system into a more traditional commercial brood facility with pre-existing birds. Turkey poults were first divided into groups raised in conventional brood pens from day-of-hatch and those raised in an experimental hatch brood system. Read More

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Building learning organizational culture during COVID-19 outbreak: a national study.

Authors:
Wadi B Alonazi

BMC Health Serv Res 2021 May 4;21(1):422. Epub 2021 May 4.

Health Administration Department, College of Business Administration, King Saud University, PO Box 71115, 11587, Riyadh, Saudi Arabia.

Background: Hospitals and healthcare institutions should be observant of the ever-changing environment and be adaptive to learning practices. By adopting the steps and other components of organizational learning, healthcare institutions can convert themselves into learning organizations and ultimately strengthen the overall healthcare system of the country. The present study aimed to examine the influence of several organizational learning dimensions on organization culture in healthcare settings during the COVID-19 outbreak. Read More

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The Impact of COVID-19 Restrictions on Mental Well-Being and Working Life among Faroese Employees.

Int J Environ Res Public Health 2021 Apr 29;18(9). Epub 2021 Apr 29.

Department of Occupational Medicine and Public Health, The Faroese Hospital System, 100 Torshavn, Faroe Islands.

The societal changes caused by COVID-19 have been far-reaching, causing challenges for employees around the world. The aim of this study was to assess the effect of the COVID-19 restrictions on mental well-being, working life, family life and social life among Faroese employees within a broad range of professions. A total of 1328 Faroese employees answered an anonymous self-report survey from 13 April to 4 May 2020. Read More

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Long-term functional outcomes after an external femoral derotation osteotomy in individuals with cerebral palsy.

Gait Posture 2021 Apr 22;87:184-191. Epub 2021 Apr 22.

Gillette Children's Specialty Healthcare, 200 University Avenue East, Saint Paul, MN, 55101, United States; University of Minnesota, Orthopedic Surgery, 2450 Riverside Ave, Minneapolis, MN, 55454, United States. Electronic address:

Background: It is unknown how a femoral derotation osteotomy (FDO) during childhood affects functional outcomes in adulthood among individuals with bilateral cerebral palsy (CP).

Research Questions: How do long-term functional outcomes after an FDO compare to matched individuals who did not have an FDO? How do outcomes change over time?

Methods: We queried the gait laboratory database for individuals who underwent an external FDO in childhood and were currently ≥25 years old. Participants returned for a long-term analysis (gait, physical examination, functional tests, imaging, questionnaires). Read More

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End-of-life decision making in critical illness: Perspectives of Asian parents.

Palliat Support Care 2021 May 4:1-10. Epub 2021 May 4.

Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore, Singapore.

Objective: To explore parents' perspectives regarding end-of-life (EOL) decisions, factors and possible barriers that influence the EOL decision making process, and to understand parental preferences for communication about EOL care in an Asian population.

Method: A prospective questionnaire cohort study conducted in a university-based tertiary care hospital. 30 parents of children who had been admitted to general pediatric wards for acute ailments and/or were being followed up in general pediatric outpatient clinics after inpatient admissions or emergency department visits completed 30 interviewer-administered questionnaires. Read More

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Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro.

ACS Biomater Sci Eng 2021 May 3. Epub 2021 May 3.

Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, People's Republic of China.

The three-dimensional (3D) marrow microenvironment plays an essential role in regulating human cord blood-derived CD34+ cells (hCB-CD34+) migration, proliferation, and differentiation. Extensive in vitro and in vivo studies have aimed to recapitulate the main components of the bone marrow (BM) niche. Nonetheless, the models are limited by a lack of heterogeneity and compound structure. Read More

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Disparities in Dental Service Use among Adult Populations in the United States.

Authors:
Y Y Wu W Zhang B Wu

JDR Clin Trans Res 2021 May 3:23800844211012660. Epub 2021 May 3.

Rory Meyers College of Nursing, New York University, New York, NY, USA.

Objectives: This article aims to examine the disparities in dental service utilization among 3 age groups: younger adults (20-49 y), middle-aged adults (50-64 y), and older adults (65+ y), among Whites, Hispanics, Blacks, Asians, American Indians or Alaska Natives (AIAN), and Native Hawaiian or other Pacific Islanders (NHOPI).

Methods: Weighted logistic regression models were conducted to analyze 9 waves of cross-sectional survey data (2002-2018) from the Behavioral Risk Factor Surveillance System. We estimated age group- and race/ethnic-specific prevalences of dental service utilization adjusting sociodemographics and self-rated health for each wave and compared with crude analysis. Read More

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Synchronization and Coordination of Art Performances in Highly Competitive Contexts: Battle Scenes of Expert Breakdancers.

Front Psychol 2021 15;12:635534. Epub 2021 Apr 15.

Graduate School of Education, The University of Tokyo, Tokyo, Japan.

In the performing arts, such as music and dance performances, people actively interact with each other and show their exciting performances. Some studies have proposed that this interaction is a social origin of the performing arts. Some have further investigated this phenomenon based on the synchronization and coordination theory. Read More

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How Packaging of Information in Conversation Is Impacted by Communication Medium and Restrictions.

Front Psychol 2021 16;12:594255. Epub 2021 Apr 16.

711th Human Performance Wing, Airman Systems Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH, United States.

In team-based tasks, successful communication and mutual understanding are essential to facilitate team coordination and performance. It is well-established that an important component of human conversation (whether in speech, text, or any medium) is the maintenance of common ground. Maintaining common ground has a number of associated processes in which conversational participants engage. Read More

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Visualization of mass transfer in mixing processes in high solid anaerobic digestion using Laser Induced Fluorescence (LIF) technique.

Waste Manag 2021 Apr 29;127:121-129. Epub 2021 Apr 29.

Laboratory of Reactions and Process Engineering, Université de Lorraine, CNRS, 1, rue Grandville, BP 20451, 54001 Nancy Cedex, France. Electronic address:

High solid anaerobic digestion (HSAD) is a promising technology for the treatment of organic waste. Mixing process in HSAD is quite difficult with long mixing time, poor homogenization, significant short-circuiting and stagnant zones. However, the mass transfer in mixing process in HSAD has not been visualized due to the lack of a proper method. Read More

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Comorbidities and Complications in Japanese Patients with Type 2 Diabetes Mellitus: Retrospective Analyses of J-DREAMS, an Advanced Electronic Medical Records Database.

Diabetes Res Clin Pract 2021 Apr 29:108845. Epub 2021 Apr 29.

Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan; Department of Molecular Diabetology, Graduate School of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan. Electronic address:

Aims: To investigate the prevalence of comorbid conditions/complications among Japanese patients with type 2 diabetes mellitus (T2DM) in a real-world setting.

Methods: We performed retrospective analyses of a large-scale database directly linked to electronic medical records, J-DREAMS (Japan Diabetes compREhensive database project based on an Advanced electronic Medical record System), to determine the prevalence of clinically significant comorbid conditions/complications among Japanese patients with T2DM aged ≥20 years with ≥1 clinical encounter at a referral center between April 1, 2017 and March 31, 2019.

Results: Data were available for 10,151 patients (39. Read More

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Investigating the impact of driving automation systems on distracted driving behaviors.

Accid Anal Prev 2021 Apr 28;156:106152. Epub 2021 Apr 28.

AAA Foundation for Traffic Safety, 607 14thStreet NW, Suite 201, Washington D.C., 20005 USA.

Driving automation systems (e.g., SAE Level 2) ultimately aim to enhance the comfort and safety of drivers. Read More

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and Co-Cultivation Extract Affects In Vitro Degradation, Fermentation Characteristics, and Bacterial Composition in a Diet-Specific Manner.

Animals (Basel) 2021 Apr 26;11(5). Epub 2021 Apr 26.

Beijing Engineering Technology Research Center of Raw Milk Quality and Safety Control, The State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

AOAN may provide enzymes to improve the digestibility of feeds and enhance rumen fermentation. This study determined the effects of AOAN on digestibility, fermentation characteristics, and bacterial composition using in vitro gas recording fermentation system. A total of 30 mg of AOAN was supplemented into 500 mg of TMR, corn silage, oat hay, and alfalfa hay. Read More

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Long-Term Safety and Efficacy of Prebiotic Enriched Infant Formula-A Randomized Controlled Trial.

Nutrients 2021 Apr 13;13(4). Epub 2021 Apr 13.

Centre of Excellence for Pediatric Research EURISTIKOS, Department of Pediatrics, University of Granada, 18071 Granada, Spain.

The present study aims to evaluate the effects of an infant formula supplemented with a mixture of prebiotic short and long chain inulin-type oligosaccharides on health outcomes, safety and tolerance, as well as on fecal microbiota composition during the first year of life. In a prospective, multicenter, randomized, double-blind study, = 160 healthy term infants under 4 months of age were randomized to receive either an infant formula enriched with 0.8 g/dL of OraftiSynergy1 or an unsupplemented control formula until the age of 12 months. Read More

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Deep Residual Networks for User Authentication via Hand-Object Manipulations.

Sensors (Basel) 2021 Apr 23;21(9). Epub 2021 Apr 23.

ImagineX Lab, Graduate School of Technology and Innovation Management, Hanyang University, Seoul 04763, Korea.

With the ubiquity of wearable devices, various behavioural biometrics have been exploited for continuous user authentication during daily activities. However, biometric authentication using complex hand behaviours have not been sufficiently investigated. This paper presents an implicit and continuous user authentication model based on hand-object manipulation behaviour, using a finger-and hand-mounted inertial measurement unit (IMU)-based system and state-of-the-art deep learning models. Read More

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Diet-Cognition Associations Differ in Mild Cognitive Impairment Subtypes.

Nutrients 2021 Apr 17;13(4). Epub 2021 Apr 17.

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, 29 Nanwei Road, Beijing 100050, China.

Cognitive function is not generally associated with diet, and there is debate over that association. Moreover, little is known about such associations with the specific cognitive domains and subtypes of mild cognitive impairment (MCI). We analyzed data of 4309 Chinese adults aged 55 and over from the Community-based Cohort Study on Nervous System Diseases from 2018-2019. Read More

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Tick Importin-α Is Implicated in the Interactome and Regulome of the Cofactor Subolesin.

Pathogens 2021 Apr 11;10(4). Epub 2021 Apr 11.

SaBio, Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain.

Ticks and tick-borne diseases (TBDs) represent a burden for human and animal health worldwide. Currently, vaccines constitute the safest and most effective approach to control ticks and TBDs. Subolesin (SUB) has been identified as a vaccine antigen for the control of tick infestations and pathogen infection and transmission. Read More

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Stable Coloured Micrometric Films from Highly Concentrated Nano-Silver Sols: The Role of the Stabilizing Agents.

Nanomaterials (Basel) 2021 Apr 10;11(4). Epub 2021 Apr 10.

Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, 20133 Milan, Italy.

The synthesis of highly concentrated aqueous silver nanoparticles (NPs), exploiting different types of polymeric stabilizing agents, has been extensively investigated, especially for the stabilization of spherical yellow nanoparticles. In this context, here, a successful and easy wet chemical method was adopted to synthesize concentrated primary colored (yellow, red, blue and green) sols. The influence of polyvinylpyrrolidone (PVP) and polyvinyl alcohol (PVA) in affecting the final stability was finely investigating via UV/Vis spectroscopy, dynamic light scattering, TEM and colorimetric analysis. Read More

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Food Consumption Pattern and the Intake of Sugar, Salt, and Fat in the South Jakarta City-Indonesia.

Nutrients 2021 Apr 14;13(4). Epub 2021 Apr 14.

Department of Functional and Organic Food, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences, Nowoursynowska 159c, 02-776 Warsaw, Poland.

The excessive consumption of sugar, salt, and fat is associated with an increased risk of non-communicable diseases. Therefore, a study on estimating the added sugar, salt, and fat intake in certain populations is important for establishing specific recommendations aiming at improving diet quality, and thus public health. This study aimed to determine the food consumption pattern and the intakes of added sugar, salt, and fat from different food groups and food sources among the residents of South Jakarta, Indonesia. Read More

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Effect of Physiological Concentrations of Vitamin C on the Inhibitation of Hydroxyl Radical Induced Light Emission from Fe-EGTA-HO and Fe-EGTA-HO Systems In Vitro.

Molecules 2021 Apr 1;26(7). Epub 2021 Apr 1.

Department of Clinical Physiology, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.

Ascorbic acid (AA) has antioxidant properties. However, in the presence of Fe/Fe ions and HO, it may behave as a pro-oxidant by accelerating and enhancing the formation of hydroxyl radicals (OH). Therefore, in this study we evaluated the effect of AA at concentrations of 1 to 200 µmol/L on OH-induced light emission (at a pH of 7. Read More

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Service user experiences of community services for complex emotional needs: A qualitative thematic synthesis.

PLoS One 2021 29;16(4):e0248316. Epub 2021 Apr 29.

Division of Psychiatry, NIHR Mental Health Policy Research Unit, University College London, London, United Kingdom.

Background: There is a recognised need to develop clear service models and pathways to provide high quality care in the community for people with complex emotional needs, who may have been given a "personality disorder" diagnosis. Services should be informed by the views of people with these experiences.

Aims: To identify and synthesise qualitative studies on service user experiences of community mental health care for Complex Emotional Needs. Read More

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Naïve CD4+ T Cell Lymphopenia and Apoptosis in Chronic Hepatitis C Virus Infection Is Driven by the CD31+ Subset and Is Partially Normalized in Direct-Acting Antiviral Treated Persons.

Front Immunol 2021 12;12:641230. Epub 2021 Apr 12.

Department of Pathology, Case Western Reserve University, Cleveland, OH, United States.

Background: The mechanisms underlying naïve CD4+ lymphopenia during chronic Hepatitis C Virus (HCV) infection are unclear. Whether direct-acting antiviral (DAA) therapy restores peripheral naïve CD4+ T cell numbers and function is unknown.

Methods: We enumerated frequencies and counts of peripheral naïve CD4+, CD4+CD31+ and CD4+CD31- T cells by flow cytometry in a cross sectional analysis comparing chronic HCV infected (n=34), DAA-treated(n=29), and age-range matched controls (n=25), as well as in a longitudinal cohort of HCV DAA treated persons (n=16). Read More

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The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life.

J Transl Med 2021 04 28;19(1):177. Epub 2021 Apr 28.

Department of Neonatal Diseases, Pomeranian Medical University in Szczecin, 70-111, Szczecin, Poland.

Background: The intestinal barrier plays an important role in the defense against infections, and nutritional, endocrine, and immune functions. The gut microbiota playing an important role in development of the gastrointestinal tract can impact intestinal permeability and immunity during early life, but data concerning this problem are scarce.

Methods: We analyzed the microbiota in fecal samples (101 samples in total) collected longitudinally over 24 months from 21 newborns to investigate whether the markers of small intestinal paracellular permeability (zonulin) and immune system development (calprotectin) are linked to the gut microbiota. Read More

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Cardiovascular response to physical exercise and the risk of Internet addiction in 15-16-year-old adolescents.

J Behav Addict 2021 Apr 27. Epub 2021 Apr 27.

N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences, Arkhangelsk, Russia.

Background And Aim: Subjective symptoms of Internet addiction (IA), such as interpersonal and health-related problems (IH-RP), do not correlate with objective physiological parameters. This study aimed to investigate the cardiovascular reactivity after physical exercise in 15-16-year-old adolescents showing different severities of symptoms of health-related problems due to Internet overuse.

Methods: This study included 20 healthy adolescents (boys, 15-16 years) with different risks of IA (by the Chen internet addiction scale [CIAS]). Read More

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