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A Gratton-like effect concerning task order in dual-task situations.

Acta Psychol (Amst) 2021 May 12;217:103328. Epub 2021 May 12.

Martin-Luther University Halle-Wittenberg, Halle, Germany.

Performing two tasks simultaneously involves the coordination of their processing. Task coordination is particularly required in dual-task situations with varying order of the component tasks. When task order switches between subsequent trials, task-order coordination leads to order switch costs in comparison to task order repetitions (i. Read More

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Subjective value, not a gridlike code, describes neural activity in ventromedial prefrontal cortex during value-based decision-making.

Neuroimage 2021 May 12:118159. Epub 2021 May 12.

Department of Psychology, University of Pennsylvania, Philadelphia, PA, 19104 USA.

Across many studies, ventromedial prefrontal cortex (vmPFC) activity has been found to correlate with subjective value during value-based decision-making. Recently, however, vmPFC has also been shown to reflect a hexagonal gridlike code during navigation through physical and conceptual space, and such gridlike codes have been proposed to enable value-based choices between novel options. Here, we first show that, in theory, a hexagonal gridlike code can in some cases mimic vmPFC activity previously attributed to subjective value, raising the possibility that the subjective value correlates previously observed in vmPFC may have actually been a misconstrued gridlike signal. Read More

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Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging C57BL/6 mice and in vitro studies.

Sci Rep 2021 May 14;11(1):10364. Epub 2021 May 14.

Department of Biological and Environmental Sciences, Qatar University, Doha, Qatar.

Rosiglitazone is an effective insulin-sensitizer, however associated with bone loss mainly due to increased bone resorption and bone marrow adiposity. We investigated the effect of the co-administration of fish oil rich in omega-3 fatty acids (FAs) on rosiglitazone-induced bone loss in C57BL/6 mice and the mechanisms underlying potential preventive effect. Mice fed the iso-caloric diet supplemented with fish oil exhibited significantly higher levels of bone density in different regions compared to the other groups. Read More

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