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Distance to water source in early childhood affects growth: a cohort study.

Public Health 2021 Apr 7;193:139-145. Epub 2021 Apr 7.

School of Economics and Resource Management, Beijing Normal University, Beijing, China. Electronic address:

Objectives: Approximately 165 million children aged <5 years are at risk of low height-for-age. This study explored whether water quality and distance to water source affected short- and long-term growth, and the critical time windows of such effects.

Study Design: This study used data from the China Health and Nutrition Survey (CHNS), which was a cohort study performed in 15 Chinese provinces. Read More

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Impact of COVID-19 on social media as perceived by the oncology community: results from a survey in collaboration with the European Society for Medical Oncology (ESMO) and the OncoAlert Network.

ESMO Open 2021 Apr 7;6(2):100104. Epub 2021 Apr 7.

Oncology Department, Centre Hospitalier Universitaire Vaudois (CHUV) and Lausanne University, Lausanne, Switzerland.

Background: The COVID-19 pandemic has impacted all aspects of modern-day oncology, including how stakeholders communicate through social media. We surveyed oncology stakeholders in order to assess their attitudes pertaining to social media and how it has been affected during the pandemic.

Materials And Methods: A 40-item survey was distributed to stakeholders from 8 July to 22 July 2020 and was promoted through the European Society for Medical Oncology (ESMO) and the OncoAlert Network. Read More

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Cranial nerve involvement in COVID-19.

Am J Otolaryngol 2021 Mar 26;42(5):102999. Epub 2021 Mar 26.

İzmir Bakırçay University Hospital, Otorhinolaryngology, Izmir, Turkey.

Introduction: The COVID-19 disease emerged in Wuhan province of China in November 2019 and spread across the world in a short time, resulting in a pandemic. The first case in Turkey was detected on March 11, 2020. The aim of the current study was to reveal the effects of COVID-19 on cranial nerves by monitoring people infected with the disease based on repeated examinations and surveys. Read More

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The Iodine Status and Prevalence of Thyroid Disorders among Women of Childbearing-age in China: National Cross-sectional Study.

Endocr Pract 2021 Apr 7. Epub 2021 Apr 7.

Department of Endocrinology and Metabolism and the Institute of Endocrinology, First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, Liaoning, China. Electronic address:

Objective: Mandatory universal salt iodization in China was implemented 20 years ago; however, the current iodine status and prevalence of thyroid disorders among childbearing-age women are unknown.

Methods: A nationally representative cross-sectional study with 26166 enrolled participants aged 18 to 49 years from all 31 provincial regions of mainland China was performed. The participants were given a questionnaire and underwent B-mode ultrasonography of the thyroid. Read More

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J Vasc Surg Venous Lymphat Disord 2021 Apr 7. Epub 2021 Apr 7.

Division of Vascular and Endovascular Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT; Vascular Malformations Program, Yale New Haven Hospital, New Haven, CT. Electronic address:

Objective: We aimed to investigate whether a current commercially available High-Intensity Focused Ultrasound (HIFU) probe can adequately image targeted vascular malformations in anticipation of HIFU treatment planning and delivery.

Methods: We enrolled 10 consecutive patients scheduled to undergo treatment of their symptomatic peripheral vascular malformations (VM) confirmed on routine preoperative contrast enhanced magnetic resonance imaging (MRI) and soft tissue duplex ultrasound (DUS). Lesions were situated no more than 6 cm from the skin. Read More

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Mental and somatic health in university students with type 1 diabetes: new results from DiaSHoT18, a cross sectional national health and well-being survey.

J Pediatr Endocrinol Metab 2021 Apr 12. Epub 2021 Apr 12.

Department of Health Promotion, Norwegian Institute of Public Health, Bergen, Norway.

Objectives: To explore mental and somatic health, quality of life, alcohol-related problems, sleep problems, and diabetes related distress in university students with type 1 diabetes (T1D), compared to students without T1D. Further, we evaluated associations with gender, treatment modalities, and achieved metabolic control.

Methods: All fulltime Norwegian students aged 18-35 years pursuing higher education in 2018 (n=162. Read More

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Association Between Low-Level Blood Cadmium Exposure and Hyperuricemia in the American General Population: a Cross-sectional Study.

Biol Trace Elem Res 2021 Apr 10. Epub 2021 Apr 10.

Department of Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.

Heavy metals, including cadmium, are suspected to increase serum uric acid levels and hyperuricemia in both gender, but the evidences about this are inconclusive. To determine whether serum cadmium in American adults(≥19 years old) is associated with uric acid levels and risk of hyperuricemia, 2620 participants from the US National Health and Nutrition Examination Survey were recruited. Hyperuricemia was defined as a serum UA concentration ≥ 416. Read More

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Health-related quality of life of a conflict-affected population in Colombia.

Qual Life Res 2021 Apr 10. Epub 2021 Apr 10.

Centre for Health Economics, University of York, York, UK.

Purpose: We assessed the validity of the EQ-5D instrument; explored correlations between area of residence's conflict intensity and individual health-related quality of life (HRQoL); and identified factors associated with HRQoL in a conflict-affected population in Colombia.

Methods: We conducted a household survey among residents of the Meta province, collecting longitudinal information about HRQoL (EQ-5D-3L instrument), health, demographic and socio-economic indicators, for years 2014 (pre-2016 peace accord), 2018 (post-peace accord) and 2019 (follow-up). After examining EQ-5D's validity, we analysed panel data using multivariate random effects models to explore associations between area conflict levels (and other factors) and HRQoL. Read More

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A survey of vocal health in church choir singers.

Eur Arch Otorhinolaryngol 2021 Apr 10. Epub 2021 Apr 10.

Department of Speech and Hearing, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

Purpose: Choir singing is an important tradition of Christian worship across India. However, vocal health issues related to the church choir singers are less addressed in the literature. Hence, this study aimed to investigate the prevalence of vocal symptoms, identify the variables associated with increased risk of voice problems and knowledge of factors influencing vocal health in church choir singers. Read More

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Evaluation of Trapping Schemes to Detect Emerald Ash Borer (Coleoptera: Buprestidae).

J Econ Entomol 2021 Apr 10. Epub 2021 Apr 10.

TEALS, LLC, Waynesburg, PA 15370, USA.

Management responses to invasive forest insects are facilitated by the use of detection traps ideally baited with species-specific semiochemicals. Emerald ash borer, Agrilus planipennis Fairmaire, is currently invading North American forests, and since its detection in 2002, development of monitoring tools has been a primary research objective. We compared six trapping schemes for A. Read More

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Examining the role of specialist palliative care in geriatric care to inform collaborations: a survey on the knowledge, practice and attitudes of geriatricians in providing palliative care.

Age Ageing 2021 Apr 9. Epub 2021 Apr 9.

School of Nursing and Midwifery, Institute for Health Transformation, Deakin University, Geelong, Victoria, Australia.

Background: The global population is ageing, and rates of multimorbidity and chronic illness are rapidly rising. Given specialist palliative care has been shown to improve overall care and reduce health care costs, how best to provide this care to older people is internationally significant.

Aim: To examine the knowledge, attitudes and practices of geriatricians in providing palliative care and working with specialist palliative care services. Read More

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Trauma Exposure and the PTSD symptoms of College Teachers During the Peak of the COVID-19 Outbreak.

Stress Health 2021 Apr 9. Epub 2021 Apr 9.

School of Sociology, Central China Normal University, People's Republic of China.

This study aimed to explore influencing factors for the psychological impact of COVID-19 on Wuhan college teachers, post-traumatic stress symptoms in particular, so as to inform evidence-based strategy development to ameliorate such adverse impacts. An online survey was conducted from 26 to 29 April 2020, and 1650 teachers (47.54% male; M=40. Read More

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Social Participation and Healthy Aging among the Elderly Japanese: the Ohsaki Cohort 2006 Study.

J Gerontol A Biol Sci Med Sci 2021 Apr 10. Epub 2021 Apr 10.

Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai, Japan.

Background: Our study examined the association between social participation and healthy aging using a community-based cohort study among Japanese elderly.

Methods: This prospective study was conducted in Ohsaki City, Japan, and included 7,226 subjects aged ≥65 years at the baseline survey in 2006. We obtained information on frequency of participation in three types of community activities (i. Read More

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Reference values for bone metabolism in a Japanese cohort survey randomly sampled from a basic elderly resident registry.

Sci Rep 2021 Apr 9;11(1):7822. Epub 2021 Apr 9.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.

The aim of this study was to provide definitive reference values for bone mineral density (BMD) and bone turnover markers in the general elderly population. Registered citizens of 50 to 89 years old were targeted for this survey. After random sampling from the resident registry of Obuse town, we established eight groups based on age (50 s, 60 s, 70 s, and 80 s) and gender. Read More

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A Pilot Randomized Controlled Trial of Interval Training and Sleep Hygiene for Improving Sleep in Older Adults.

J Aging Phys Act 2021 Apr 9:1-10. Epub 2021 Apr 9.

The primary objective of this pilot randomized controlled trial was to study the feasibility (recruitment and retention rates) for interval training and sleep hygiene (SH) in adults aged above 60 years. Thirteen out of 46 screened individuals from a home for older adults in Shirdi (Maharashtra, India) were randomly assigned by permuted block randomization to either an interval training with SH group (n = 6) or an SH alone group (n = 7). The authors measured sleep with the S+ sleep monitor manufactured by ResMed (USA) Pittsburgh Sleep Quality Index and quality of life with Short Form-12 health survey version 2. Read More

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Impact of COVID-19 pandemic on mental health among general Bangladeshi population: a cross-sectional study.

BMJ Open 2021 Apr 9;11(4):e045727. Epub 2021 Apr 9.

Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh

Objectives: Mental health problems significantly increased worldwide during the coronavirus (COVID-19) pandemic. At the early stage of the outbreak, the government of Bangladesh imposed lockdown and quarantine approaches to prevent the spread of the virus, which impacted people's daily life and health. The COVID-19 pandemic has also affected people's economic status, healthcare facilities and other lifestyle factors in Bangladesh. Read More

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Magnitude and associated factors of unmet need for family planning among rural women in Ethiopia: a multilevel cross-sectional analysis.

BMJ Open 2021 Apr 9;11(4):e044060. Epub 2021 Apr 9.

School of Nursing, College of Medicine and Health Sciences and Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.

Objective: This study was aimed to assess the magnitude and associated factors of unmet need for family planning among rural women in Ethiopia.

Design: Cross-sectional study.

Setting: Ethiopia. Read More

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Relationship between workers' return to work, job retention and income in industrial accidents in Korea: a longitudinal study.

BMJ Open 2021 Apr 9;11(4):e039948. Epub 2021 Apr 9.

Graduate School of Public Health, Yonsei University, Seoul, South Korea

Objective: This study aims to compare workers' income before and after an occupational injury, with regard to return to work and job retention, over a period of 5 years.

Design: This study was designed as a longitudinal study.

Setting: The Panel Study of Workers' Compensation Insurance (PSWCI) survey targeted workers involved in industrial accidents for which medical care was terminated in the year 2012. Read More

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Web-Based Radiology Learning Module Design: The Author Perspective.

Acad Radiol 2021 Apr 6. Epub 2021 Apr 6.

Department of Radiology, University of North Carolina School of Medicine, North Carolina.

Rationale And Objectives: Over recent years, e-learning has become an integral component of radiology education. While demands for innovative, interactive e-learning resources have increased, the availability of viable solutions have not kept pace. As a result, many educators are authoring their own e-learning content. Read More

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The orthopaedic surgeon's clinical and experimental experience affect methods used for the fracture healing assessment (FHA) - An International Survey.

Injury 2021 Mar 23. Epub 2021 Mar 23.

Ziv Medical Center, Orthopaedic unit, Tsfat, Israel.

Detection of fracture healing (FH), which depends on assessment methods, is a crucial factor affecting treatment. The study aimed to examine orthopedic surgeons in terms of practical methods of fracture healing (FHA) assessment (physical, imaging, measurement, and laboratory) and to check whether surgeons participating in clinical and laboratory experiments or only clinical practitioners prefer different FHA methods. An International Survey on Fracture Healing Assessment Methods was developed and distributed through the Web-based survey portal. Read More

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Breaking the Age Barrier: Physicians' Perceptions on Candidacy for Allogeneic Hematopoietic Cell Transplantation in Older Adults.

Transplant Cell Ther 2021 Apr 6. Epub 2021 Apr 6.

City of Hope, Duarte, CA.

Background: Despite continued increases in use of allogeneic hematopoietic cell transplantation (alloHCT) among older adults, no standardized geriatric assessment (GA) has been established to risk-stratify for transplant-related morbidity. We conducted a survey of transplant physicians to determine perceptions of the impact of older age (≥60 years) on alloHCT candidacy, and utilization of tools to gauge candidacy.

Methods: We conducted a 23-item, online cross-sectional survey of HCT physicians caring for adults in the United States between May and July 2019. Read More

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The role of monoamine oxidase enzymes in the pathophysiology of neurological disorders.

J Chem Neuroanat 2021 Apr 6:101957. Epub 2021 Apr 6.

Department of Anthropology and School of Biomedical Sciences, Kent State University, Kent, OH, USA; Brain Health Research Institute, Kent State University, Kent, OH, USA.

Although it has been nearly 100 years since the first description of monoamine oxidase, we are still learning about its role in the healthy brain and how it is altered in various disease states. The present review provides a survey of our current understanding of monoamine oxidases, with a focus on their contributions to neuropsychiatric, neurodevelopmental, and neurodegenerative disease. Important species differences in monoamine oxidase function and development in the brain are highlighted. Read More

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Research Funding, Income, and Career Satisfaction among Clinician-Scientists in Ophthalmology in the United States.

Am J Ophthalmol 2021 Apr 6. Epub 2021 Apr 6.

Department of Ophthalmology and Vision Sciences, University of California, Davis, Sacramento. Electronic address:

Purpose: To characterize clinician-scientists in ophthalmology and identify factors associated with successful research funding, income, and career satisfaction.

Design: Cross-sectional study METHODS: We conducted a survey of clinician-scientists in ophthalmology at U.S. Read More

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Analysis of the Time-To-Onset and Factors Affecting Clinical Outcomes of Immune Reconstitution Inflammatory Syndrome in People Living with HIV Using Data from the Japanese Spontaneous Reporting Database.

J Pharm Pharm Sci 2021 ;24:153-160

Purpose: Data on immune reconstitution inflammatory syndrome (IRIS), despite being a widely recognized complication of antiretroviral therapy, remain limited. The objective of the present study was to evaluate the time-to-onset and factors affecting clinical outcomes of IRIS in people living with HIV (PLWH) using data from the Japanese Adverse Drug Event Report (JADER) database.

Methods: Data of PLWH who developed IRIS as an adverse event were extracted from the JADER database. Read More

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January 2021

Asian carp: A threat to American lakes, a feast on Chinese tables.

Compr Rev Food Sci Food Saf 2021 Apr 9. Epub 2021 Apr 9.

Beijing Laboratory for Food Quality and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China.

Asian carp, which are widely distributed in Asia and Europe, are nutritious and popular with consumers. In China, Asian carp is a tasty dish and has been consumed for thousands of years. However, they are considered aggressive invasive species that threaten rivers, lakes, and indigenous species in the United States. Read More

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Tendencies and attitudes towards dietary supplements use among undergraduate female students in Bangladesh.

PLoS One 2021 9;16(4):e0249897. Epub 2021 Apr 9.

Department of Biochemistry and Molecular Biology, University of Chittagong, Chittagong, Bangladesh.

Background: Dietary supplements (DS) are products that improve the overall health and well-being of individuals and reduce the risk of disease. Evidence indicates a rising prevalence of the use of these products worldwide especially among the age group 18-23 years.

Aim: The study investigates the tendencies and attitudes of Bangladeshi undergraduate female students towards dietary supplements (DS). Read More

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Demand satisfied by modern contraceptive among married women of reproductive age in Kenya.

PLoS One 2021 9;16(4):e0248393. Epub 2021 Apr 9.

International Centre for Reproductive Health, Mombasa, Kenya.

Background: Demand for family planning met/satisfied with modern contraceptive methods (mDFPS) has been proposed to track progress in Family Planning (FP) programs for Sustainable Development Goals. This study measured mDFPS among married women of reproductive age (MWRA) in Kenya to identify which groups were not being reached by FP programs.

Materials And Methods: Performance, Monitoring and Accountability 2020 (PMA2020) survey data from 2014-2018 was used. Read More

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Health-Related Quality of Life With Trastuzumab Monotherapy Versus Trastuzumab Plus Standard Chemotherapy as Adjuvant Therapy in Older Patients With HER2-Positive Breast Cancer.

J Clin Oncol 2021 Apr 9:JCO2002751. Epub 2021 Apr 9.

Biostatistics Division, Clinical Research Support Center, The University of Tokyo Hospital, Tokyo, Japan.

Purpose: We report findings on quality of life (QoL) in the RESPECT trial, which compared adjuvant trastuzumab monotherapy with trastuzumab plus chemotherapy in older patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC).

Patients And Methods: Patients age 70-80 years with human epidermal growth factor receptor 2-positive surgically treated breast cancer were randomly assigned to receive trastuzumab (T) or trastuzumab plus chemotherapy (T + C). QoL was assessed using the Functional Assessment of Cancer Therapy-General (FACT-G), Philadelphia Geriatric Center Morale Scale, Hospital Anxiety and Depression Scale, Patient Neurotoxicity Questionnaire, and Tokyo Metropolitan Institute of Gerontology Index of Competence at baseline and after 2, 12, and 36 months. Read More

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Frailty in relation to psycho-social factors in elderly patients with rheumatoid arthritis: A cross-sectional mixed qualitative-quantitative study.

Int J Rheum Dis 2021 Apr 9. Epub 2021 Apr 9.

Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands.

Aim: The aim of the study was to explore in patients with rheumatoid arthritis (RA) ≥55 years: (1) whether the occurrence of frailty as measured by the Groningen Frailty Indicator (GFI) increases with age (survey 1); and (2) to gain insight into which frailty characteristics (eg, loneliness) contribute to frailty (survey 2).

Methods: The GFI was assessed in 3 age groups (55-64/65-74/≥75-years), ensuring equal representation. GFI-subdomains that discriminated most between those classified as frail were further studied in a subset of patients using validated domain-specific questionnaires (eg Hospital Anxiety and Depression Scale [HADS]) and semi-structured interviews. Read More

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Oral immunotherapy in severe cow's milk allergic patients treated with omalizumab: real life survey from a Spanish registry.

Pediatr Allergy Immunol 2021 Apr 9. Epub 2021 Apr 9.

Department of Allergy, Hospital Infantil Universitario Niño Jesús and ARADyAL- RETICs network RD16, Instituto de Salud Carlos III, IIS-P, FibHNJ, 0006/0026, Madrid, Spain.

Background: Oral immunotherapy is a frequent treatment for the management of food allergies, but adverse events (AE) are common. This study assessed the outcome of cow's milk oral immunotherapy (MOIT) in severe cow`s milk allergic patients treated with omalizumab in a real-life setting.

Methods: OmaBASE was a national, multicenter, open and observational registry that collected clinical, immunological and treatment data from patients with food allergy receiving omalizumab. Read More

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