3,940,356 results match your criteria surgical interventions


Should Transanal Total Mesorectal Excision Be Implemented in Medium-Sized Colorectal Unit? Technical and Oncological Outcome.

Ann Coloproctol 2021 Jul 28. Epub 2021 Jul 28.

Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

Purpose: This study was performed to evaluate the outcome of implementation of transanal total mesorectal excision (TaTME) for low rectal cancer in a regional hospital and in comparison to laparoscopic (Lap) TME.

Methods: Consecutive patients with low rectal cancer of which the lowest border of the tumour was located beween 1 and 5 cm from the puborectalis who underwent TME at North District Hospital between January 2013 and December 2019 were included. Clinical, operative, and pathologic outcomes were compared between Lap TME and TaTME. Read More

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Transperitoneal laparoscopic ureteropyeloplasty of retrocaval ureter: Single surgeon experience and review of literature.

Asian J Endosc Surg 2021 Jul 28. Epub 2021 Jul 28.

Department of Urology, GMC Jammu, Jammu, India.

Introduction: Retrocaval ureter (RCU) is a rare congenital abnormality, secondary to anomalous development of inferior vena cava (IVC) presenting as ipsilateral obstruction needing surgical intervention. The aim of this article is to present surgical techniques and outcome of transperitoneal laparoscopic ureteropyeloplasty in patients with RCU treated by a single surgeon at a tertiary care center and with review of literature.

Material And Methods: We conducted a retrospective, institutional review board approved chart review of patients who underwent transperitoneal laparoscopic ureteropyeloplasty for RCU at our unit between January 2010 and December 2020. Read More

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The prognostic significance of neuroendocrine markers and somatostatin receptor 2 in hepatocellular carcinoma.

Pathol Int 2021 Jul 28. Epub 2021 Jul 28.

Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

Prostatic and colon carcinomas with neuroendocrine differentiation are reported to behave more aggressively than those without such differentiation. In hepatocellular carcinomas (HCCs), however, only a few studies have reported the expression status of neuroendocrine markers and somatostatin receptor 2, the main target of a somatostatin analog. Furthermore, the prognostic significance of the markers in HCCs has not been fully explored. Read More

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[Update cochlear-implantation: indications and surgical aspects].

Laryngorhinootologie 2021 Aug 28;100(8):652-672. Epub 2021 Jul 28.

In childhood, inadequately rehabilitated hearing loss leads to impaired language acquisition and social, mental and emotional development. In adults, social withdrawal due to limited communication skills is often a consequence of unsatisfactory hearing rehabilitation. Therefore, in patients with profound hearing loss, the indication for cochlear implantation should be considered. Read More

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THE ROLE OF CHEST CT IN DECIPHERING INTERSTITIAL LUNG INVOLVEMENT: SYSTEMIC SCLEROSIS VERSUS COVID-19.

Rheumatology (Oxford) 2021 Jul 28. Epub 2021 Jul 28.

Department of Experimental and Clinical Medicine, University of Florence, and Infectious and TropicalDiseases Unit, AOUC, Florence, Italy.

Objective: To identify the main computed tomography (CT) features that may help distinguishing a progression of interstitial lung disease (ILD) secondary to Systemic sclerosis (SSc) from COVID-19 pneumonia.

Methods: This multicentric study included 22 international readers divided in the radiologist group (RAD) and non-radiologist group (nRAD). A total of 99 patients, 52 with COVID-19 and 47 with SSc-ILD, were included in the study. Read More

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Dangers of a single pellet.

N Z Med J 2021 Jul 9;134(1538):148-149. Epub 2021 Jul 9.

MBChB, FRACS; Consultant General Surgeon, Gisborne Hospital.

Recent figures suggest gun violence in New Zealand is on the rise. Between 6,000 and 8,000 shotguns are imported annually. The challenge specific to managing shotgun injury is the wide field of damage caused by multiple pellets. Read More

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Outcomes following open radical cystectomy: an 11-year Christchurch experience.

N Z Med J 2021 Jul 30;134(1539):63-73. Epub 2021 Jul 30.

Statistician, University of Otago, Christchurch, New Zealand.

Background: Radical cystectomy (RC) remains the standard approach to treating muscle invasive bladder cancer. Despite improvements in surgical and anaesthetic care, morbidity and mortality remain high. In the United Kingdom, centralisation has improved outcomes following RC. Read More

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Feasibility and Outcomes of Corneal Transplantation Performed at Rural Centers: An Extension of the Pyramidal Model of Enhanced Eye Care at Rural Outreach.

Cornea 2021 Jul 28. Epub 2021 Jul 28.

Allen Foster Community Eye Health Research Centre, Gullapalli Pratibha Rao International Centre for Advancement of Rural Eye Care, LV Prasad Eye Institute, Hyderabad, India; Indian Health Outcomes, Public Health and Economics (IHOPE) Research Centre, LVPEI, Hyderabad, Telangana, India; Cornea Service, The Cornea Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India; Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India; and School of Optometry and Vision Science, University of New South Wales, Sydney, Australia.

Purpose: The aim of this study was to report on the feasibility of setting up a system of corneal transplants at rural outreach centers and report the outcomes of the first 111 cases.

Methods: Retrospective analysis of the outcomes of corneal transplantation performed on patients with optical indications between March 2016 and September 2019 at 4 secondary (rural) centers. The centers are a part of a network in the pyramidal model developed by L V Prasad Eye Institute. Read More

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Descemet Stripping Automated Endothelial Keratoplasty in Pediatric Age Group: A Decade of Our Experience.

Cornea 2021 Jul 28. Epub 2021 Jul 28.

Centre for Rare Eye Diseases and Ocular Genetics, L V Prasad Eye Institute, Hyderabad, India; The Cornea Institute, L V Prasad Eye Institute, Hyderabad, India; Jasti V Ramanamma Children's Eye Care Center, L V Prasad Eye Institute, Hyderabad, India; Ophthalmic Biophysics, L V Prasad Eye Institute, Hyderabad, India; Ramayamma International Eye Bank, L V Prasad Eye Institute, Hyderabad, India; and Department of Ophthalmology and Visual Sciences and Pathology, University of Illinois College of Medicine, Chicago, IL.

Purpose: This study was to report the outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) in managing corneal endothelial disorders in children less than 14 years of age.

Methods: Medical records of 180 DSAEK performed, between 2008 and 2020, on 167 eyes of 111 children who had a visually significant endothelial dysfunction were retrospectively reviewed for the primary etiology of corneal decompensation, time of the onset and duration of cloudiness, preoperative visual acuity, the technique of endothelial keratoplasty, surgical modifications, and reintervention.

Results: Median age at surgical intervention was 7. Read More

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High Rates of Incisional Hernia After Laparoscopic Right Colectomy With Midline Extraction Site.

Surg Laparosc Endosc Percutan Tech 2021 Jul 28. Epub 2021 Jul 28.

Department of Surgery Department of Imaging, Rabin Medical Center, Beilinson Hospital, Petach Tikva Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Laparoscopic surgery aims at reducing wound complications and improving cosmetics, among other advantages. High rates of postoperative ventral hernia (POVH) are observed after laparoscopic-assisted colectomies.

Materials And Methods: In a 2011 to 2016 retrospective study of all patients at Rabin Medical Center, we examined POVH prevalence after right hemicolectomy for neoplasia and correlation to specimen extraction site. Read More

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Intraoperative Measures to Reduce the Risk of COVID-19 Transmission During Minimally Invasive Procedures: A Systematic Review and Critical Appraisal of Societies' Recommendations.

Surg Laparosc Endosc Percutan Tech 2021 Jul 28. Epub 2021 Jul 28.

Medical Affairs, Ethicon Inc., Cincinnati, OH.

Background: The coronavirus 2019 pandemic and the hypothetical risk of virus transmission through aerosolized CO2 or surgical smoke produced during minimally invasive surgery (MIS) procedures have prompted societies to issue recommendations on measures to reduce this risk. The aim of this systematic review is to identify, summarize and critically appraise recommendations from surgical societies on intraoperative measures to reduce the risk of severe acute respiratory syndrome coronavirus 2 transmission to the operative room (OR) staff during MIS.

Methods: Medline, Embase, and Google Scholar databases were searched using a search strategy or free terms. Read More

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Fully Guided Zygomatic Implant Surgery.

J Craniofac Surg 2021 Jul 27. Epub 2021 Jul 27.

Tuscan Dental Institute, Private Practice, Vicenza Tuscan Dental Institute, Padova Tuscan Dental Institute, Lido di Camaiore Private Practice, Tuscan Dental Institute, Naples, Italy.

Introduction: Rehabilitating a severely atrophic maxilla is a complex procedure. In case of severe resorption, zygomatic implants are indicated and loading of the implants at the end of the surgery is desirable. We present a new method by means of guided surgery for the placement of zygomatic implants, using specially designed metal templates that should be supported by bone. Read More

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Immediate Resection and Reconstruction of Encephalocele in the Craniofacial Region.

J Craniofac Surg 2021 Jul 27. Epub 2021 Jul 27.

Department of Neurosurgery, Third People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.

Introduction: Congenital meningoencephalocele is a herniation of brain and meninges through a skull base defect. It may result not only in neural defects, sensorimotor deficits, neurological morbidities, visual impairment, impaired nasal function, and a potential risk of intracranial infection. Goals of surgery include removal or repositioning of nonfunctional cerebral tissue, closure of the dura, and reconstruction of skeletal and cutaneous structures. Read More

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Outcome Measurement of Beauty and Attractiveness of Facial Aesthetic Rejuvenation Surgery.

J Craniofac Surg 2021 Jul 27. Epub 2021 Jul 27.

Division of Plastic and Reconstructive Surgery, American University of Beirut Medical Center Trad Hospital Medical Center, Beirut, Lebanon.

Abstract: Aesthetic plastic surgery is a most unusual and unique subspecialty. Unlike other medical and surgical specialties driven primarily by objective medical diagnosis and outcome, aesthetic surgery is patient driven; it represents a special exercise in professional competence by adapting objective medical standards to a mostly subjective field. Given the subjectivity of facial beauty and of the projected aesthetic intervention outcome, in addition to be able to determine beauty of the final result as precisely and objectively as possible, it is also essential to be able to assess patient's satisfaction. Read More

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Surgical Management of Bilateral Osteoradionecrosis of the Mandible.

J Craniofac Surg 2021 Jul 27. Epub 2021 Jul 27.

Department of Oral Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine National Clinical Research Center for Oral Disease Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, Shanghai, China.

Purpose: The purpose of this study was to evaluate our 10 years clinical experience in surgical management of patients with bilateral osteoradionecrosis (BORN) of the mandible in head and neck malignancies patients.

Materials And Methods: The authors reviewed 22 patients with bilateral mandibular bone mineral density changed in image who had failed to respond to conservative treatments. They were treated by radical resection and reconstruction with free flaps immediately or second-stage at our institution between January 2008 and January 2018. Read More

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Treatment Effects and Lip Profile Changes Following Surgical Mandibular Advancement Versus Premolar Extractions in Class II Div 1 Malocclusion: A Randomized Controlled Trial.

J Craniofac Surg 2021 Jul 27. Epub 2021 Jul 27.

Government Dental Center ADC R&R Hospital, New Delhi Government Dental Center, Pune Jabalpur Hospital, Jabalpur Institute of Dental Sciences, Mumbai, India.

Abstract: No randomized controlled trial has compared the treatment outcome between surgical mandibular advancement and premolar extractions in class II malocclusion. This 2-arm parallel randomized controlled trial evaluated the treatment effects and lip profile changes in skeletal class II adult patients subjected to bilateral sagittal split ramus osteotomy for mandibular advancement and those treated with premolar extractions. Seventy skeletal class II patients were accessed and forty-six subjects who fulfilled inclusion criteria were distributed randomly into Group CG (patients: 23, mean age: 21. Read More

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Successful Outcomes and Return to Sport After Arthroscopic Bankart Repair in National Collegiate Athletic Association and National Football League Football Players.

Clin J Sport Med 2021 Jul 27. Epub 2021 Jul 27.

Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, Washington; Department of Orthopedics and Sports Medicine, Seattle Children's, Seattle, Washington; Medical College of Georgia, Augusta, Georgia; Orlin & Cohen Orthopedic Group, Woodbury, New York; and The Andrews Research and Education Foundation, Gulf Breeze, Florida.

Objective: To characterize recurrent instability, return to sport (RTS), and patient-reported outcomes (PROs) after arthroscopic Bankart repair for acute traumatic anterior shoulder instability in National Collegiate Athletic Association (NCAA) and National Football League (NFL) football players.

Design: Case series.

Setting: Orthopaedic and sports medicine clinic. Read More

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Hyperthermic intraperitoneal chemotherapy for treating ovarian cancer.

JAAPA 2021 Aug;34(8):50-53

Shilpa Gajarawala is lead PA in the Department of Medical and Surgical Gynecology and an assistant professor of obstetrics and gynecology at Mayo Clinic Florida College of Medicine and Science in Jacksonville, Fla. She also is an adjunct faculty member in the doctor of medical science program at Rocky Mountain University of Health Science in Provo, Utah. Jessica Pelkowski practices in the Department of Orthopedic Surgery at the Mayo Clinic Florida. Rose Dorian practices in the Department of Blood and Marrow Transplantation and Cellular Immunotherapy at Moffitt Cancer Center in Tampa, Fla. Amanda Stanton practices in the Department of Medical and Surgical Gynecology and is an instructor in obstetrics and gynecology at the Mayo Clinic Florida. Tri Dinh is an assistant professor of obstetrics and gynecology at the Mayo Clinic Florida. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Abstract: Hyperthermic intraperitoneal chemotherapy (HIPEC) has been used for decades as a treatment for disseminated abdominal malignancies, including pseudomyxoma peritonei and peritoneal mesothelioma. HIPEC had been used to treat recurrent ovarian cancer only when curative options were lacking, but new data indicate that it may be suitable as a primary treatment for patients with late-stage epithelial ovarian cancer, increasing the recurrence-free time interval and improving quality of life. However, treatment can be challenging because of patient trauma from surgery, combined with the toxicity and high temperature of the chemotherapeutic agents. Read More

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Complications of a congenital iris cyst in a newborn.

JAAPA 2021 Aug;34(8):40-42

At the time this article was written, Catherine Nelson was a student in the PA program at Marietta (Ohio) College. She now is a hospitalist PA at Genesis Healthcare System in Zanesville, Ohio. Bradley Pierce is an associate professor in the PA program at Marietta College and practices in the Department of Medical Oncology at Memorial Health System in Belpre, Ohio. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Abstract: Congenital iris cysts are a rare condition in infants that can lead to multiple complications. This report describes an infant born with an iris cyst who developed complications including secondary glaucoma, cataracts, and visual impairment, requiring management with multiple surgical interventions and medications. Read More

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The Perceived Knowledge of Fall Prevention in Nurses Working in Acute Care Hospitals in China and the United States.

J Patient Saf 2021 May 14. Epub 2021 May 14.

From the Departments of Transitional Care First Class Ward, The First Affiliated Hospital, Jinan University, Guangzhou, China Crystal M. Lange College Health and Human Service, Saginaw Valley State University Covenant Healthcare, Saginaw MidMichigan Health, Midland MI.

Objective: The aim of the study was to investigate the perceived knowledge of fall prevention in nurses working in hospitals in China and the United States.

Methods: A cross-sectional survey with 17 items was used to measure perceived knowledge of fall prevention of nurses working in hospitals in China and the United States.

Results: A total of 1442 nurses at 2 hospitals completed the survey in China (90% return rate), and 260 nurses in 2 hospitals in the United States (42% return rate) for a total sample size of 1702. Read More

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Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature.

Pediatr Neurosurg 2021 Jul 28:1-10. Epub 2021 Jul 28.

Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.

Introduction: Tumor-associated intracranial aneurysms are rare and not well understood.

Case Presentation: We describe a 4-year-old female with multiple intracranial aneurysms intimately associated with a suprasellar germ cell tumor (GCT). We provide the clinical history, medical, and surgical treatment course, as well as a comprehensive and concise synthesis of the literature on tumor-associated aneurysms. Read More

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Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer.

Neoplasia 2021 Jul 25;23(9):898-911. Epub 2021 Jul 25.

Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST), "G. d' Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy; Oncoxx Biotech, 66034 Lanciano (Chieti), Italy; Unit of Medical Genetics, Department of Biomedical Sciences - BIOMORF, University of Messina, 98125 Messina, Italy. Electronic address:

We recently reported that activation of Trop-2 through its cleavage at R87-T88 by ADAM10 underlies Trop-2-driven progression of colon cancer. However, the mechanism of action and pathological impact of Trop-2 in metastatic diffusion remain unexplored. Through searches for molecular determinants of cancer metastasis, we identified TROP2 as unique in its up-regulation across independent colon cancer metastasis models. Read More

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Maximum Standardized Uptake Value on Positron Emission Tomography is Associated with More Advanced Disease and High-risk Features in Lung Adenocarcinoma.

Semin Thorac Cardiovasc Surg 2021 Jul 25. Epub 2021 Jul 25.

Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) has been widely used for preoperative staging of lung adenocarcinomas. The aim of this study was to determine whether a high maximum standardized uptake value (SUVmax) could correlate with pathological characteristics in those patients. We retrospectively reviewed patients with clinical stage 0-IA lung adenocarcinoma who underwent preoperative FDG-PET/CT followed by curative anatomical resection. Read More

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Commentary: Outcomes of Surgical Aortic Valve or Root Replacement in Patients on Hemodialysis: Lessons Learned and Remaining Challenges.

Authors:
Ko Bando

Semin Thorac Cardiovasc Surg 2021 Jul 25. Epub 2021 Jul 25.

Department of Cardiac Surgery, The Jikei University School of Medicine, Tokyo, Japan. Electronic address:

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Right atrial papillary fibroelastoma arising from the Chiari network detected by echocardiography: a case report and literature review.

Cardiovasc Pathol 2021 Jul 25:107372. Epub 2021 Jul 25.

Department of Ultrasound, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China; Department of Ultrasound, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences. Electronic address:

Purpose: To improve our understanding of cardiac papillary fibroelastoma(PFE)and provide evidence for its treatment and prognosis.

Materials And Methods: We report a 54-year-old Chinese male who was hospitalized for a 14-day headache with a previous vertebral aneurysm history. A right atrial mass arising from the CN was detected by echocardiography and complete tumor resection was performed finally. Read More

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Are orthopaedic providers willing to work overtime to address COVID-19-related patient backlogs and financial deficits?

Bone Jt Open 2021 Jul;2(7):562-568

Department of Orthopedic Surgery, Henry Ford Health Systems, Detroit, Michigan, USA.

Aims: COVID-19-related patient care delays have resulted in an unprecedented patient care backlog in the field of orthopaedics. The objective of this study is to examine orthopaedic provider preferences regarding the patient care backlog and financial recovery initiatives in response to the COVID-19 pandemic.

Methods: An orthopaedic research consortium at a multi-hospital tertiary care academic medical system developed a three-part survey examining provider perspectives on strategies to expand orthopaedic patient care and financial recovery. Read More

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Surgical navigation for challenging recurrent or pretreated intra-abdominal and pelvic soft tissue sarcomas.

J Surg Oncol 2021 Jul 28. Epub 2021 Jul 28.

Department of Surgical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

Background: This study assessed whether electromagnetic navigation can be of added value during resection of recurrent or post-therapy intra-abdominal/pelvic soft tissue sarcomas (STS) in challenging locations.

Materials And Methods: Patients were included in a prospective navigation study. A pre-operatively 3D roadmap was made and tracked using electromagnetic reference markers. Read More

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Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive.

Eur J Immunol 2021 Jul 28. Epub 2021 Jul 28.

MRC Centre for Transplantation Immunology, School of Immunology and Microbial Sciences, King's College London, London, UK.

Clinical trials of regulatory T cell therapy in transplantation are currently entering phases IIa and IIb, with the majority of these employing polyclonal Treg populations which harbour a broad specificity. Enhancing Treg specificity is possible with the use of chimeric antigen receptors (CAR), which can be customized to respond to a specific human leukocyte antigen (HLA). In this study, we build on our previous work in the development of HLA-A2 CAR-Tregs by further equipping cells with the constitutive expression of interleukin 10 (IL-10) and an imaging reporter as additional payloads. Read More

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A Crowdsourced Consensus on Supratotal Resection Versus Gross Total Resection for Anatomically Distinct Primary Glioblastoma.

Neurosurgery 2021 Jul 28. Epub 2021 Jul 28.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Background: Gross total resection (GTR) of contrast-enhancing tumor is associated with increased survival in primary glioblastoma. Recently, there has been increasing interest in performing supratotal resections (SpTRs) for glioblastoma.

Objective: To address the published results, which have varied in part due to lack of consensus on the definition and appropriate use of SpTR. Read More

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Early Outcomes After Carotid Endarterectomy and Carotid Artery Stenting: A Propensity-Matched Cohort Analysis.

Neurosurgery 2021 Jul 28. Epub 2021 Jul 28.

Department of Neurosurgery, Rhode Island Hospital, Lifespan Health System, Providence, Rhode Island, USA.

Background: Carotid endarterectomy (CEA) and carotid artery stenting (CAS) represent options to treat many patients with carotid stenosis. Although randomized trial data are plentiful, estimated rates of morbidity and mortality for both CEA and CAS have varied substantially.

Objective: To evaluate rates of adverse outcomes after CAS and CEA in a large national database. Read More

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