Search Our Scientific Publications & Authors

J Neurosurg 2021 Apr 9:1-14. Epub 2021 Apr 9.

Departments of1Neurological Surgery and.

Objective: Posterior fossa decompression with duraplasty (PFDD) is often used for Chiari malformation type I (CM-I), but outcomes associated with different dural graft materials are not well characterized. In this meta-analysis, the authors examined complication rates and outcomes after PFDD for CM-I for autografts and four types of nonautologous grafts.

Methods: A literature search of numerous electronic databases (Ovid Medline, Embase, Scopus, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews of Effects, Health Technology Assessment Database, NHS Economic Evaluation Database, and ClinicalTrials. Read More

J Neurosurg 2021 Apr 9:1-16. Epub 2021 Apr 9.

2Department of Neurosurgery, Stanford Hospital, Stanford, California.

Objective: The lateral posterior choroidal artery (LPChA) should be a major surgical consideration in the microsurgical management of lateral ventricular tumors. Here the authors aim to delineate the microsurgical anatomy of the LPChA by using anatomical microdissections. They describe the trajectory, segments, and variations of the LPChA and discuss the surgical implications when approaching the choroid plexus using different routes. Read More

J Neurosurg Spine 2021 Apr 9:1-6. Epub 2021 Apr 9.

1Orthopedic Surgery, Sanmu Medical Center, Chiba, Japan; and.

Objective: Diffuse idiopathic skeletal hyperostosis (DISH)-related vertebral fractures essentially require operative treatment due to severe fracture site instability and high potential risk of posttraumatic neurological deficit. However, the optimal surgical procedure remains unclear. The purpose of this study was to assess the efficacy of posterior spinal fixation with penetrating endplate screws (PESs) for DISH-related thoracolumbar fractures. Read More

J Neurosurg Pediatr 2021 Apr 9:1-9. Epub 2021 Apr 9.

Departments of5Neurosurgery and.

Objective: Neurosurgical residents receive exposure to the subspecialty of pediatric neurosurgery during training. The authors sought to determine resident operative experience in pediatric neurosurgery across Accreditation Council for Graduate Medical Education (ACGME)-accredited neurosurgical programs.

Methods: During 2018-2019, pediatric neurosurgical case logs for recent graduates or current residents who completed their primary pediatric exposure were collected from US continental ACGME training programs. Read More

Clin Biomech (Bristol, Avon) 2021 Mar 27;84:105340. Epub 2021 Mar 27.

Department of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.

Background: Trochlear dysplasia is highly associated with patellofemoral instability. The goal of conservative and surgical treatment is to stabilize the patella while minimizing adverse effects. However, there is no literature investigating the quantitative influence of different treatment options on patellofemoral stability in knees with trochlear dysplasia. Read More

Cancer Genet 2021 Mar 24;256-257:21-25. Epub 2021 Mar 24.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States. Electronic address:

Background: Adrenocortical carcinoma (ACC) is a rare malignancy arising from the adrenal cortex. ACC carries a dismal prognosis and surgery offers the only chance for a cure. Germline pathogenic variants among certain oncogenes have been implicated in ACC. Read More

Comput Biol Med 2021 Apr 1;133:104360. Epub 2021 Apr 1.

College of Medical and Dental Sciences, Institute of Cancer and Genomic Sciences, University of Birmingham, UK; Institute of Translational Medicine, University Hospitals Birmingham, NHS Foundation Trust, UK; NIHR Experimental Cancer Medicine Centre, UK; NIHR Surgical Reconstruction and Microbiology Research Centre, UK; NIHR Biomedical Research Centre, UK; MRC Health Data Research UK (HDR UK) Midlands, UK; University Hospitals Birmingham NHS Foundation Trust, Edgbaston, Birmingham, UK.

Ontology-based phenotype profiles have been utilised for the purpose of differential diagnosis of rare genetic diseases, and for decision support in specific disease domains. Particularly, semantic similarity facilitates diagnostic hypothesis generation through comparison with disease phenotype profiles. However, the approach has not been applied for differential diagnosis of common diseases, or generalised clinical diagnostics from uncurated text-derived phenotypes. Read More

J Surg Res 2021 Apr 6;264:179-185. Epub 2021 Apr 6.

Department of Surgery, Division of Vascular Surgery, University of Iowa, Iowa City, Iowa. Electronic address:

Objective: Frailty scores are increasingly utilized to predict postoperative complications. The purpose of this study is to determine whether the administrative risk analysis index (RAI-A) can be used to predict reintervention or mortality within 30 days in patients who undergo elective open or endovascular abdominal aortic aneurysm (AAA) repair.

Methods: The American College of Surgeons National Surgical Quality Improvement Program database was used to query data from elective open or endovascular aortic aneurysm repairs from 2011 to 2018. Read More

J Surg Res 2021 Apr 6;264:173-178. Epub 2021 Apr 6.

Michigan Opioid Prescribing and Engagement Network, Ann Arbor, Michigan; Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan.

Background: Larger opioid prescriptions are associated with increased consumption without improvements in pain, and the majority of opioids prescribed go unused. We examined postoperative opioid prescription and use in patients undergoing vascular access surgery, where preoperative opioid exposure is common.

Methods: A retrospective analysis was conducted in adult CKD patients who underwent outpatient vascular access surgery. Read More

Complement Ther Clin Pract 2021 Apr 2;43:101385. Epub 2021 Apr 2.

Department of Surgical Nursing, Faculty of Nursing, Inonu University, Malatya, Turkey. Electronic address:

Background: The aim of the study was to examine the effect of Acupressure and Reiki application on patient's pain and comfort level after Laparoscopic cholecystectomy.

Materials And Methods: In this prospective, single blinded randomized controlled trial, subjects were 132 adult patients, hospitalized in the General Surgery clinics and underwent laparoscopic cholecystectomy of a Training and Research Hospital in Turkey. Subjects were then assigned including a Reiki group of 44 persons, an Acupressure group of 44 persons, and a control group of 44 persons. Read More

Musculoskelet Sci Pract 2021 Mar 24;53:102370. Epub 2021 Mar 24.

Department of Medical Surgical-Therapy, Medicine Faculty, Extremadura University, Badajoz, Spain.

Background: Nonspecific chronic low back pain (NSCLBP) is one of the most common and frequent health problems. OBJETIVE: to compare postural control (i.e. Read More

Am J Emerg Med 2021 Apr 2;48:38-47. Epub 2021 Apr 2.

Department of Surgery, Division of Trauma and Surgical Critical Care, Kendall Regional Medical Center, Miami, FL, USA. Electronic address:

Background: Emergency medicine (EM) physicians have been on the front line of the COVID-19 pandemic. This study aims to determine the impact of COVID-19 pandemic and other related factors such as resource availability and institutional support on well-being, burnout and job-satisfaction of EM physicians in the United States.

Methods: A cross-sectional survey study of EM physicians was conducted through the Emergency Medicine Practice Research Network of the ACEP. Read More

Orthop Traumatol Surg Res 2021 Apr 6:102922. Epub 2021 Apr 6.

MINTOS - Medical Imaging and Navigation in Trauma and Orthopaedic Surgery, BG Trauma Center Ludwigshafen, Heidelberg University Hospital, Ludwig-Guttmann-Str. 13, 67071 Ludwigshafen, Germany. Electronic address:

Background: Despite a substantial improvement in the operative treatment of tibial plateau fractures, the surgical procedure remains controversial and is generally challenging, as patients may develop postoperative arthritis and functional impairment of the knee joint.

Hypothesis: In the surgical treatment of tibial plateau fractures the intraoperative reposition quality has the greatest influence on the postoperative outcome, whereby misalignments of >/= 2 mm lead to a worse result.

Patients And Methods: 41 patients with tibial plateau fractures were postoperatively examined. Read More

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Division of Vascular and Endovscular Surgery, Department of Surgery, Saint Louis University. Electronic address:

Introduction: The novel coronavirus SARS-CoV-2 (COVID-19) has spread rapidly since it was identified. We sought to understand its effects on vascular surgery practices stratified by VASCON surgical readiness level and determine how these effects have changed during the course of the pandemic.

Methods: All members of the Vascular and Endovascular Surgery Society were sent electronic surveys questioning the effects of COVID-19 on their practices in the early pandemic in April (EP) and four months later in the pandemic in August (LP) 2020. Read More

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Belgrade; Faculty of Medicine, University of Belgrade, Serbia.

Introduction: The aim of this paper is to report our single-center experience in the open surgical treatment of acute spontaneous infrarenal isolated abdominal aortic dissection (siIAAD).

Methods And Patients: This was a single center retrospective study. Between January 2015 and 2020 ten patients were treated due to acute siIAAD with open surgery. Read More

J Surg Oncol 2021 Apr 9. Epub 2021 Apr 9.

Section of Surgical Oncology, Division of Surgery, Baptist MD Anderson Cancer Center, Jacksonville, Florida, USA.

Background: Clinical and pathologic staging determine treatment of pancreatic cancer. Clinical stage has been shown to underestimate final pathologic stage in pancreatic cancer, resulting in upstaging.

Methods: National Cancer Database was used to identify clinical stage I pancreatic adenocarcinoma. Read More

J Surg Oncol 2021 Apr 9. Epub 2021 Apr 9.

Department of Urology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.

BACKGROUND AND OBJECTIVE: This study aimed to evaluate the safety and efficacy of robot-assisted laparoscopic tumor enucleation (RAE) for the treatment of renal hilar tumors and to describe our experience with renorrhaphy-related surgical techniques.

Methods: Retrospective data were collected from 173 consecutive patients who underwent RAE for localized renal tumors (cT1-cT2N0M0) at our hospital between September 2014 and November 2019.

Results: Seventy-five patients had renal hilar tumors and 98 patients had nonhilar tumors. Read More

Angle Orthod 2021 Apr 9. Epub 2021 Apr 9.

Objectives: The objectives were to evaluate and compare the presence of bone dehiscence before and after orthognathic surgery.

Materials And Methods: In this retrospective study, 90 cone-beam computed tomography (CBCT) scans from 45 patients were evaluated. Class II (n = 23) and Class III (n = 22) orthodontic patients who were being prepared for orthognathic surgery were measured. Read More

JBJS Case Connect 2021 Apr 9;11(2). Epub 2021 Apr 9.

Department of Trauma and Orthopaedics, Royal Stoke University Hospital, Stoke on Trent, Staffordshire, United Kingdom.

Case: We present 2 unusual scapula fractures that do not meet published thresholds for surgical intervention; 1 initially managed surgically with a good functional result and 1 conservatively with a poor outcome. The second patient subsequently underwent osteotomy and fixation with good effect.

Conclusion: Despite not reaching published levels of displacement or angulation usually considered for surgical intervention, these cases demonstrate that combined patterns of scapula injury can cause functional disability if managed conservatively. Read More

Pancreas 2021 Mar;50(3):386-392

From the Division of Surgical Oncology, Department of Surgery, University of Pittsburgh Medical Center Cancer Pavilion, Pittsburgh, PA.

Objectives: The objective of this study was to create a composite measure, optimal oncologic surgery (OOS), for patients undergoing distal pancreatectomy for pancreatic adenocarcinoma and identify factors associated with OOS.

Methods: Adult patients undergoing distal pancreatectomy were identified from the National Cancer Database between 2010 and 2016. Patients were stratified based on receipt of OOS. Read More

Pancreas 2021 Mar;50(3):306-312

From the Division of Surgical Oncology, DeWitt Daughtry Family Department of Surgery.

Objectives: Colloid carcinoma (CC) of the pancreas is associated with an improved prognosis compared with pancreatic ductal adenocarcinoma (PDAC), yet studies on the optimal management of these rare lesions are lacking.

Methods: Patients with CC or PDAC treated from 2004 to 2014 were identified in the National Cancer Database. Clinicopathologic characteristics were compared between groups and stratified by disease stage. Read More

IEEE J Biomed Health Inform 2021 Apr 9;PP. Epub 2021 Apr 9.

Cataract causes more than half of all blindness worldwide. The most effective treatment is surgery, where cataract is often replaced by intraocular lens (IOL). Beyond saving vision, toric IOL implantation is becoming increasingly popular to correct corneal astigmatism. Read More

J Laparoendosc Adv Surg Tech A 2021 Apr 8. Epub 2021 Apr 8.

Department of Surgery, City of Hope National Medical Center, Duarte, California, USA.

While robotic surgery has grown in popularity and scope over the past decade, there is a persistent need for simulation-based training as surgeons adapt from the working at the bedside to the immersive and multisensory tasks at the console. From dry laboratory to virtual reality (VR) environments, simulation can be used to train surgeons in basic tasks, complex operative steps, and coordination of whole operations with members of the entire operating room (OR) staff. By integrating simulation into mentored training programs, surgeons can reduce the number of cases required to master a complex operation. Read More

Integr Cancer Ther 2021 Jan-Dec;20:1534735420975853

University of Turin, Turin, Italy.

Objectives: To assess whether preoperative levels of physical activity predict the incidence of post-operative complications following anatomical lung resection.

Methods: Levels of physical activity (daily steps) were measured for 15 consecutive days using pedometers in 90 consecutive patients (prior to admission). Outcomes measured were cardiac and respiratory complications, length of stay, and 30-day re-admission rate. Read More

J Adolesc Young Adult Oncol 2021 Apr 9. Epub 2021 Apr 9.

Department of Reproductive Medicine, Gunasheela Surgical and Maternity Hospital, Bangalore, India.

To descriptively explore semen quality among Indian men with various types of malignancies. We evaluated semen parameters of male patients referred to our hospital before commencing their cancer treatment. Four hundred sixty-one male patients who were within the age range of 15-50 years were recruited with diagnosed malignancies. Read More

Dentomaxillofac Radiol 2021 Apr 9:20210030. Epub 2021 Apr 9.

Department of Radiology, Hunan Children's Hospital, Changsha, China.

Objective: To retrospectively analyze magnetic resonance imaging (MRI) features of various pathological subtypes of sinonasal rhabdomyosarcoma (RMS) and explore correlations between imaging features and pathological subtypes.

Methods: In total, 11 cases with embryonal, alveolar or pleomorphic sinonasal RMSs, confirmed by surgical pathology, were selected. Their characteristics and distinctive imaging features were analysed, and the correlation between pathology and imaging features was explored. Read More

Head Neck 2021 Apr 9. Epub 2021 Apr 9.

Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA.

Background: Levels of circulating hybrid cells (CHCs), a newly identified circulating tumor cell (CTC), correlate with disease stage and progression in cancer. We investigated their utility to risk-stratify patients with clinically N0 (cN0) oral cavity squamous cell carcinoma (OCSCC), and to identify patients with occult cervical lymph node metastases (pN+).

Methods: We analyzed peripheral blood samples for CHCs with co-expression of cytokeratin (tumor) and CD45 (leukocyte) from 22 patients with cN0 OCSCC using immunofluorescence microscopy, then correlated levels with pathologic lymph node status. Read More

Wound Repair Regen 2021 Apr 9. Epub 2021 Apr 9.

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School, Hannover, Germany.

Pyoderma gangrenosum is a diagnosis of exclusion. It occurs rarely and is frequently misdiagnosed. It can result in severe tissue loss, particularly in surgical units with little experience. Read More

Br J Dermatol 2021 Apr;184(4):e126-e147

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing skin cancer that is primarily treated with surgery. Because this cancer can spread deep into the skin and surrounding tissue in an irregular way, it is notoriously difficult to ensure that it has been completely removed after conventional surgery and histological examination. Standard treatment in the UK is either wide local excision (WLE) or Mohs micrographic surgery (MMS). Read More

Spine Deform 2021 Apr 9. Epub 2021 Apr 9.

IRCCS Istituto Ortopedico Rizzoli (IOR), via G. C. Pupilli 1, 40136, Bologna, Italy.

Purpose: To evaluate the efficacy of pre-operative low-dose radiation computed tomography (CT) in optimizing screw placement in patients with adolescent idiopathic scoliosis (AIS).

Methods: 49 patients with AIS who required correction and posterior fusion between January 2018 and December 2019 were included in this retrospective study. All patients underwent surgery performed by the same team of experienced surgeons. Read More