291,137 results match your criteria surgery single

Increased hypospadias risk by rs3743104[G] in the southern Han Chinese population.

Aging (Albany NY) 2021 May 7;13. Epub 2021 May 7.

Department of Pediatric Urology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.

Hypospadias is a common congenital genitourinary malformation characterized by ventral opening of the urethral meatus. As a member of the bone morphogenic protein antagonist family, has been identified as associated with susceptibility to hypospadias in the European population. The present study was designed to elaborate on the mutual relationship between replicated single-nucleotide polymorphisms (SNPs) and hypospadias in Asia's largest case-control study in the Southern Han Chinese population involving 577 patients and 654 controls. Read More

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Single dose perioperative intrathecal ketamine as an adjuvant to intrathecal bupivacaine: A systematic review and meta-analysis of adult human randomized controlled trials.

J Clin Anesth 2021 May 4;73:110331. Epub 2021 May 4.

Zucker School of Medicine at Hofstra/Northwell, Department of Anesthesiology, Northwell Health, New Hyde Park, NY, United States of America.

Study Objective: To identify whether adding intrathecal ketamine to intrathecal bupivacaine prolongs the time to first analgesic request in adult humans.

Design: A meta-analysis of randomized controlled trials in humans.

Setting: The majority of data was obtained in an operating room and postoperative recovery area. Read More

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Long term outcomes of idiopathic intracranial hypertension: Observational study and literature review.

Clin Neurol Neurosurg 2021 Jan 5;205:106463. Epub 2021 Jan 5.

Department of Ophthalmology, Faculty of Medical and Health Sciences, University of Auckland, New Zealand. Electronic address:

Background: Idiopathic intracranial hypertension (IIH) is an unexplained increase in intracranial pressure often associated with obesity. The aim of this study was to conduct a retrospective observational study of the long term clinical, visual, and treatment outcomes in IIH patients.

Methods: A retrospective observational study of patients diagnosed with IIH over a 12-year period at a single centre was completed via database review. Read More

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January 2021

Genicular artery embolization for refractory hemarthrosis following total knee arthroplasty: technique, safety, efficacy, and patient-reported outcomes.

J Vasc Interv Radiol 2021 May 4. Epub 2021 May 4.

The Department of Radiology, Division of Interventional Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, United States.

Purpose: This single institution study describes the technique, safety, and efficacy of genicular artery embolization (GAE) for treatment of refractory hemarthrosis following total knee arthroplasty (TKA) with a focus on patient-reported outcomes.

Material And Methods: Patients who underwent GAE between January 2010 and March 2020 at the authors' institution were included if they had undergone TKA and subsequently experienced recurrent hemarthrosis. Embolization was performed using spherical microparticles. Read More

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Suppression of Epithelial to Mesenchymal Transition Markers in Mouse Lens by a Smad7-based Recombinant Protein.

Chem Biol Interact 2021 May 4:109495. Epub 2021 May 4.

Department of Ophthalmology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, 80045, United States; Department of Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, 80045, United States. Electronic address:

Cataracts, a clouding of the eye lens, are a leading cause of visual impairment and are responsible for one of the most commonly performed surgical procedures worldwide. Although generally safe and effective, cataract surgery can lead to a secondary lens abnormality due to transition of lens epithelial cells to a mesenchymal phenotype (EMT) and opacification of the posterior lens capsular bag. Occurring in up to 40% of cataract cases over time, posterior capsule opacification (PCO) introduces additional treatment costs and reduced quality of life for patients. Read More

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Low dose of methylprednisolone for pain and immune function after thoracic surgery.

Ann Thorac Surg 2021 May 4. Epub 2021 May 4.

Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, P.R. China. Electronic address:

Background: The purpose of this study was to evaluate the effects of single low-dose preoperative methylprednisolone (MP) on the immunological function and postoperative pain of patients undergoing elective video-assisted thoracoscopic surgery under general anesthesia.

Methods: Eighty-one patients who underwent elective video-assisted thoracoscopic surgery were randomly assigned to the MP Group or the Control Group. The T lymphocyte subsets of CD3, CD4, and CD8, the CD4/CD8 ratio at T (before anesthesia), T (after surgery), and T (24 h after surgery) were all recorded. Read More

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Evaluation of a marker independent isolation method for circulating tumor cells in esophageal adenocarcinoma.

PLoS One 2021 7;16(5):e0251052. Epub 2021 May 7.

Department of Gastro-Intestinal Surgery, University Hospital Ghent, Ghent, Belgium.

Objective: The enrichment of circulating tumor cells (CTCs) from blood provides a minimally invasive method for biomarker discovery in cancer. Longitudinal interrogation allows monitoring or prediction of therapy response, detection of minimal residual disease or progression, and determination of prognosis. Despite inherent phenotypic heterogeneity and differences in cell surface marker expression, most CTC isolation technologies typically use positive selection. Read More

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Red light emitting diode as an adjuvant treatment for epidermal growth factor receptor inhibitors-induced paronychia.

J Dermatolog Treat 2021 May 7:1-16. Epub 2021 May 7.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Skin and Allergy Research Unit, Chulalongkorn University, Bangkok, Thailand.

We evaluated the efficacy and safety of red light LED as an adjuvant treatment for epidermal growth factor receptor inhibitor-induced paronychia. Eight patients were recruited in this randomized, single-blinded controlled trial. They were randomized to receive red-light on one hand or foot 2-3 times/week for 6 weeks while the contralateral side served as controls. Read More

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Adhesive small bowel obstruction in elderly patients: a single-center analysis of treatment strategies and clinical outcomes.

Scand J Gastroenterol 2021 May 7:1-7. Epub 2021 May 7.

Digestive Surgery Unit, Fondazione Policlinico Agostino Gemelli IRCCS di Roma, Rome, Italy.

Introduction: The incidence of adhesive bowel obstruction (ASBO) progressively increases with age. Strong evidences on the influencing role of age on ASBO clinical course and management are still lacking. Aim of this study is to retrospectively analyze the clinical outcomes of patients older than 65 years of age admitted to a tertiary referral Emergency Department with a diagnosis of ASBO. Read More

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Characterization of Blue Light Treatment for Infected Wounds: Antibacterial Efficacy of 420, 455, and 480 nm Light-Emitting Diode Arrays Against Common Skin Pathogens Versus Blue Light-Induced Skin Cell Toxicity.

Photobiomodul Photomed Laser Surg 2021 May;39(5):339-348

Chair, Department of Virology and Microbiology, Centre for Biomedical Education and Research (ZBAF), University Witten/Herdecke, Witten, Germany.

To determine effective treatment strategies against bacterial infections of chronic wounds, we tested different blue light (BL)-emitting light-emitting diode arrays (420, 455, and 480 nm) against wound pathogens and investigated in parallel BL-induced toxic effects on human dermal fibroblasts. Wound infection is a major factor for delayed healing. Infections with and are clinically relevant caused by their ability of biofilm formation and their quickly growing antibiotics resistance. Read More

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Ectopic Cushing's syndrome due to thymic neuroendocrine tumours: a systematic review.

Rev Endocr Metab Disord 2021 May 7. Epub 2021 May 7.

Department of Endocrinology, Bellvitge University Hospital, Biomedical Research Institute of Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

Knowledge of ectopic Cushing's syndrome (CS) due to thymic neuroendocrine tumours (NETs) comes from short series or single cases. Our aim is to perform a systematic review using PubMed, Embase, Scopus, Ovid Medline and Biosis Previews of all cases with ectopic CS due to thymic NETs reported in the last 40 years and describe one illustrative patient attended in our institution. Search of literature: From 162 patients, 58. Read More

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The impact of loco-regional anaesthesia on postoperative opioid use in elderly hip fracture patients: an observational study.

Eur J Trauma Emerg Surg 2021 May 7. Epub 2021 May 7.

Department of Anesthesiology, Luzerner Kantonsspital, Luzern, Switzerland.

Purpose: Hip fractures are a common health problem among the elderly with an increasing incidence. They are associated with high mortality and morbidity. Optimal pain management remains challenging and inadequate pain control is known for negatively affecting outcomes. Read More

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Endoscopic lung volume reduction coils for patients with severe emphysema-a single-centre retrospective analysis.

Interact Cardiovasc Thorac Surg 2021 May 7. Epub 2021 May 7.

Department of Pneumology, Allergology and Critical Care Medicine, ECLS Center Saar, Saarland University Hospital, Homburg/Saar,Germany.

Objectives: Patients with chronic obstructive pulmonary disease and lung emphysema may benefit from surgical or endoscopic lung volume reduction (ELVR). Previously reported outcomes of nitinol coil-based ELVR techniques have been ambiguous. The analysis was done to analyse outcomes of ELVR with nitinol coils in patients with severe pulmonary emphysema. Read More

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Impact of dialysis in patients undergoing bioprosthetic aortic valve replacement.

Interact Cardiovasc Thorac Surg 2021 May 7. Epub 2021 May 7.

Department of Cardiovascular Surgery, Kokura Memorial Hospital, Fukuoka, Japan.

Objectives: To determine the incidence of bioprosthetic structural valve deterioration in dialysis patients undergoing aortic valve replacement compared to that in patients without dialysis.

Methods: This single-centre retrospective observational study included 1159 patients who underwent aortic valve replacement using bioprosthetic valves for aortic stenosis and/or regurgitation at our institution between 2007 and 2017 [patients with dialysis (group D, n = 134, 12%) or without dialysis (group N, n = 1025, 88%)]. To adjust for potential differences between groups in terms of initial preoperative characteristics or selection bias, a propensity score analysis was conducted. Read More

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Mucin Expression in Mucinous Pancreatic Cysts: Can String Sign Test Predict Mucin Types? A Single Center Pilot Study.

Turk J Gastroenterol 2021 Feb;32(2):187-193

Department of Gastroenterology, Bezmialem Vakif University School of Medicine, İstanbul, Turkey.

Background: Mucinous pancreatic cystic lesions (PCLs) express different mucin (MUC) types according to their histomorphologic types. High cystic fluid viscosity may help in the detection of mucinous PCLs. We hypothesized that high cystic fluid viscosity may be suggestive of a certain MUC type in mucinous PCLs. Read More

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February 2021

Preoperative Alpha-Fetoprotein Has No Prognostic Role in Small Hepatocellular Carcinoma in Non-Cirrhotic Patients After Surgical Resection.

Turk J Gastroenterol 2021 Feb;32(2):133-140

Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.

Background: Alpha-fetoprotein (AFP) has been widely used as a tumor marker in the treatment of hepatocellular carcinoma (HCC) in patients with cirrhosis. However, a large number of HCC patients are diagnosed without cirrhosis, and the prognostic capability of AFP was unclear in HCC patients without cirrhosis. Our purpose was to investigate the prognostic efficiency of AFP in patients with non-cirrhosis, single, and small HCC who were treated with surgical resection. Read More

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February 2021

[Simultaneous Bilateral Femoral Osteotomies in Neurogenic Hip Instability: a Feasibility Study].

Acta Chir Orthop Traumatol Cech 2021 ;88(2):95-100

Oddělení ortopedie a traumatologie, AGEL Středomoravská nemocniční a.s., Nemocnice Přerov.

PURPOSE OF THE STUDY The study aimed to evaluate the intraoperative and early postoperative response to simultaneous bilateral femoral osteotomy usually accompanied by soft tissue release of hip joints, or open reduction, capsuloplasty, pelvic osteotomy or extraarticular shelf procedure. MATERIAL AND METHODS A bilateral surgery was performed in 16 children. Twelve children suffered from (spastic) cerebral palsy and there was one case of paralytic dislocation in a patient with myelomeningocele, while the remaining patients suffered from chromosome I aberrations, Dandy-Walker syndrome and merosin-deficient muscular dystrophy. Read More

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January 2021

Evaluation of Operative Notes for Splenic Flexure Mobilization: Are the Key Aspects Being Reported?

J Laparoendosc Adv Surg Tech A 2021 May 6. Epub 2021 May 6.

Department of Surgery, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA.

Given the importance of operative documentation, we reviewed operative notes for surgeries that required splenic flexure mobilization (SFM) to determine their accuracy. We performed a retrospective review of 51 operative notes for complete SFMs performed at a single institution from January 2015 to June 2020. None of the operative notes reported a rationale for performing SFM, use of preoperative imaging to guide technical approach, reasoning for the operative method and mobilization approach used, or specific steps taken to ensure that SFM was done safely. Read More

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Requirement of Mental-Health Referral Letters for Staged and Revision Genital Gender-Affirming Surgeries: An Unsanctioned Barrier to Care.

Andrology 2021 May 7. Epub 2021 May 7.

Cedars-Sinai Transgender Surgery and Health Program, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Background: The World Professional Association for Transgender Health (WPATH) recommends referral letters from two mental-health providers within one year of gender-affirming genital surgery (gGAS) to ensure patient readiness before primary surgeries. Many U.S. Read More

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Benefits of Early Ambulation in Elderly Patients Undergoing Lumbar Decompression and Fusion Surgery: A Prospective Cohort Study.

Orthop Surg 2021 May 7. Epub 2021 May 7.

Department of Spine Surgery, Beijing Jishuitan Hospital, Beijing, China.

Objective: To evaluate the effects of early ambulation on elderly patients' postoperative physical functional outcomes, complications, 90-day readmission rate, and the length of postoperative hospital stay.

Methods: This is a prospective cohort study conducted between June 2019 and December 2019. The study enrolled 86 elderly patients (39 males) with newly diagnosed lumbar degenerative disease undergoing single-segment decompression and fusion surgerywere enrolled. Read More

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The expansion of no-touch harvesting sequential vein graft after off-pump coronary artery bypass grafting.

J Card Surg 2021 May 7. Epub 2021 May 7.

Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Background And Aim Of The Study: Many studies support that the no-touch (NT) procedure can improve the patency rate of vein grafts. However, it is not clear that the sequential vein graft early expansion in the NT technique during off-pump coronary artery bypass grafting (CABG). This study will explore this issue. Read More

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What is the current clinico-radiological diagnostic accuracy for intracranial tumours?

Acta Neurol Scand 2021 May 7. Epub 2021 May 7.

Department of Neurosurgery, St. Olav's University Hospital, Trondheim, Norway.

Objective: To determine the diagnostic accuracy of routine clinico-radiological workup for a population-based selection of intracranial tumours.

Methods: In this prospective cohort study, we included consecutive adult patients who underwent a primary surgical intervention for a suspected intracranial tumour between 2015 and 2019 at a single-neurosurgical centre. The treating team estimated the expected diagnosis prior to surgery using predefined groups. Read More

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Improving the WHO Surgical Safety Checklist sign-out.

BJS Open 2021 May;5(3)

Department for Continuing Education, University of Oxford, Oxford, UK.

Background: The WHO Surgical Safety Checklist has been shown to reduce perioperative morbidity and mortality worldwide. There is evidence to suggest that sign-out is the most poorly performed phase of the checklist as it coincides with a period of high workload for team members. This study aimed to see whether modification of this process might result in greater compliance. Read More

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The hemodynamic effects of warm versus room-temperature crystalloid fluid bolus therapy in post-cardiac surgery patients.

Perfusion 2021 May 7:2676591211012204. Epub 2021 May 7.

Department of Intensive Care, Austin hospital, Melbourne, Australia.

Introduction: The contribution of fluid temperature to the effect of crystalloid fluid bolus therapy (FBT) in post-cardiac surgery patients is unknown. We evaluated the hemodynamic effects of FBT with fluid warmed to 40°C (warm FBT) versus room-temperature fluid.

Methods: In this single centre prospective before-and-after study, we evaluated the effects of 500 ml of warm versus room-temperature compound sodium lactate administered over <30 minutes, in 50 cardiac surgery patients admitted to ICU. Read More

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Temporal Incidence and Predictors of High-Grade Atrioventricular Block After Transcatheter Aortic Valve Replacement.

J Am Heart Assoc 2021 May 7:e020033. Epub 2021 May 7.

Department of Cardiovascular Medicine Mayo Clinic Rochester MN.

Background The temporal incidence of high-grade atrioventricular block (HAVB) after transcatheter aortic valve replacement (TAVR) is uncertain. As a result, periprocedural monitoring and pacing strategies remain controversial. This study aimed to describe the temporal incidence of initial episode of HAVB stratified by pre- and post-TAVR conduction and identify predictors of delayed events. Read More

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Comorbidity Burden and Adverse Outcomes After Transcatheter Aortic Valve Replacement.

J Am Heart Assoc 2021 May 7:e018978. Epub 2021 May 7.

Division of Cardiology Tufts Medical Center Boston MA.

Background Transcatheter aortic valve replacement (TAVR) has become the preferred treatment for symptomatic patients with aortic stenosis and elevated procedural risk. Many deaths following TAVR are because of noncardiac causes and comorbid disease burden may be a major determinant of postprocedure outcomes. The prevalence of comorbid conditions and associations with outcomes after TAVR has not been studied. Read More

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Discordant SARS-CoV-2 Detection in the Nasopharynx versus Trachea for Patients with Tracheostomies.

Laryngoscope 2021 May 6. Epub 2021 May 6.

Department of Otolaryngology - Head and Neck Surgery, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, Michigan, 48109.

Objective: Patients with tracheostomies have an anatomically altered connection between their upper and lower airways that could impact SARS-CoV-2 testing. Our goal was to evaluate for discordance in SARS-CoV-2 detection in hospitalized patients with COVID-19 and tracheostomies based on the site analyzed.

Methods: This single-institution study evaluated hospitalized patients with COVID-19 who had tracheostomies placed during their treatment. Read More

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Serum cortisol and adrenocorticotrophic hormone (ACTH) in infants receiving topical and subconjunctival corticosteroids following cataract surgery.

Graefes Arch Clin Exp Ophthalmol 2021 May 6. Epub 2021 May 6.

Ophthalmology Department, Faculty of Medicine, Cairo University, 16 Abd El-Hady Street Manial, Cairo, 114511, Egypt.

Purpose: Cushingoid features are occasionally encountered in infants after pediatric cataract surgery. The aim of this study is to evaluate whether the use of topical glucocorticoids (GCs) following congenital cataract surgery can result in endogenous adrenal suppression and/or systemic side effects similar to those seen with systemic steroids.

Methods: A prospective study was performed on 20 infants with bilateral congenital cataract. Read More

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High incidence of potentially preventable emergency department visits after major elective colorectal surgery.

Surg Endosc 2021 May 6. Epub 2021 May 6.

Department of Surgery, McGill University Health Centre, Glen Campus-DS1.3310, 1001 Decarie Boulevard, Montreal, QC, H3G 1A4, Canada.

Introduction: Emergency department (ED) visits after surgery represent a significant cost burden on the healthcare system. Furthermore, many ED visits are related to issues of healthcare delivery services and may be avoidable. Few studies have assessed the reasons for ED visits after colorectal surgery. Read More

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The association between intracompartmental pressure and skeletal muscle recovery after tibial diaphyseal fractures: an ambispective cohort study.

J Orthop Traumatol 2021 May 6;22(1):18. Epub 2021 May 6.

Department of Radiology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, China.

Background: Due to the special anatomy of the lower leg, tibial diaphyseal fracture causes increased intracompartmental pressure (ICP). Not only is this increased ICP the manifestation of skeletal muscle injury, but it induces further deterioration of the injury. The aim of this study was to assess the association between short-term ICP elevation and long-term skeletal muscle recovery after severe limb trauma. Read More

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