508,725 results match your criteria surgery children

Typical Crossmodal Numerosity Perception in Preterm Newborns.

Multisens Res 2021 May 12:1-22. Epub 2021 May 12.

Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris, 56128 Calambrone, Pisa, Italy.

Premature birth is associated with a high risk of damage in the parietal cortex, a key area for numerical and non-numerical magnitude perception and mathematical reasoning. Children born preterm have higher rates of learning difficulties for school mathematics. In this study, we investigated how preterm newborns (born at 28-34 weeks of gestation age) and full-term newborns respond to visual numerosity after habituation to auditory stimuli of different numerosities. Read More

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The effect of musculoskeletal model scaling methods on ankle joint kinematics and muscle force prediction during gait for children with cerebral palsy and equinus gait.

Comput Biol Med 2021 May 5;134:104436. Epub 2021 May 5.

Department of Exercise Sciences, The University of Auckland, Auckland, New Zealand. Electronic address:

Clinical gait analysis incorporated with neuromusculoskeletal modelling could provide valuable information about joint movements and muscle functions during ambulation for children with cerebral palsy (CP). This study investigated how imposing pre-calculated joint angles during musculoskeletal model scaling influence the ankle joint angle and muscle force computation. Ten children with CP and equinus gait underwent clinical gait analysis. Read More

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Initial Clinical Trial of A Novel Pulmonary Valved Conduit.

Semin Thorac Cardiovasc Surg 2021 May 10. Epub 2021 May 10.

Department of Cardiac Surgery, University Hospital, University of Zürich, Switzerland.

Valved allografts and xenografts for reconstruction of the right ventricular outflow tract (RVOT) lack durability and do not grow. We report the first clinical use of a completely bioabsorbable valved conduit (Xeltis pulmonary valve - XPV) in children. Twelve children (six male), median age five (two to twelve) years and median weight 17 (10 to 43) kg, underwent RVOT reconstruction with the XPV. Read More

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Does perioperative respiratory event increase length of hospital stay and hospital cost in pediatric ambulatory surgery?

PLoS One 2021 13;16(5):e0251433. Epub 2021 May 13.

Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.

Objective: We examined the consequences of perioperative respiratory event (PRE) in terms of hospitalization and hospital cost in children who underwent ambulatory surgery.

Methods: This subgroup analysis of a prospective cohort study (ClinicalTrials.gov: NCT02036021) was conducted in children aged between 1 month and 14 years who underwent ambulatory surgery between November 2012 and December 2013. Read More

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Isolation of intact extracellular vesicles from cryopreserved samples.

PLoS One 2021 13;16(5):e0251290. Epub 2021 May 13.

Department of Surgery, Center for Engineering in Medicine and BioMEMS Resource Center Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.

Extracellular vesicles (EVs) have emerged as promising candidates in biomarker discovery and diagnostics. Protected by the lipid bilayer, the molecular content of EVs in diverse biofluids are protected from RNases and proteases in the surrounding environment that may rapidly degrade targets of interests. Nonetheless, cryopreservation of EV-containing samples to -80°C may expose the lipid bilayer to physical and biological stressors which may result in cryoinjury and contribute to changes in EV yield, function, or molecular cargo. Read More

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Can laboratory findings predict pulmonary involvement in children with COVID-19 infection?

Pediatr Pulmonol 2021 May 13. Epub 2021 May 13.

Department of Pediatric Infectious Diseases, University of Health Sciences Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, İzmir, Turkey.

Background: Studies investigating clinical and imaging findings of coronavirus disease 2019 (COVID-19) pneumonia and predictors for lung injury mostly focus on adults. In this study, we aimed to evaluate the role of laboratory findings in predicting lung involvement in children with COVID-19.

Methods: Children with COVID-19 confirmed by reverse-transcription polymerase chain reaction or COVID-19 IgM and who underwent chest computed tomography (CT) scans were reviewed retrospectively. Read More

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Paediatric facial paralysis: An overview and insights into management.

J Paediatr Child Health 2021 May 13. Epub 2021 May 13.

The Welsh Centre of Burns and Plastic Surgery, Morriston Hospital, Swansea, United Kingdom.

The aim of this article is to provide an overview on paediatric facial paralysis, looking into aetiology, epidemiology, assessment and investigation and subsequent treatment options available. Facial paralysis describes the inability to activate the muscles of fascial expression. Overall, it affects 2. Read More

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A Multicenter Pilot Randomized Clinical Trial of a Home-Based Exercise Program for Patients With Cirrhosis: The Strength Training Intervention (STRIVE).

Am J Gastroenterol 2021 Apr;116(4):717-722

1Department of Medicine, University of California-San Francisco, San Francisco, California, USA; 2Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; 3Department of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 4Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Introduction: We developed the strength training intervention (STRIVE), a home-based exercise program targeting physical function in patients with cirrhosis. In this pilot study, we aimed to evaluate the safety and efficacy of STRIVE.

Methods: Eligible were adult patients with cirrhosis at 3 sites. Read More

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ACG Clinical Report and Recommendations on Transition of Care in Children and Adolescents With Hereditary Polyposis Syndromes.

Am J Gastroenterol 2021 Apr;116(4):638-646

1Division of Gastroenterology, Hepatology and Nutrition, Children's Mercy Hospital, Kansas City, MO, USA; 2University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA; 3Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA; 4St Mark's Hospital Polyposis Registry, Harrow, United Kingdom; 5Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children and the Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Canada; 6Center for Behavioral Health, Neurological Institute, Cleveland Clinic, Cleveland OH, USA; 7Department of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA; 8Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Transition of care (TOC) in adolescents and young adults (AYAs) with chronic gastrointestinal disorders has received increased attention, especially in those with inflammatory bowel disease. AYAs with hereditary polyposis syndromes are a heterogeneous group of patients with overlapping and complex medical needs. These patients are particularly vulnerable because of the risk of loss of continuity of care and subsequent poor disease outcomes. Read More

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Outcomes of Pediatric Liver Transplantation in Japan: A Report from the Registry of the Japanese Liver Transplantation Society (JLTS).

Transplantation 2021 Jan 19. Epub 2021 Jan 19.

1. Transplantation Center, National Center for Child Health and Development, Tokyo, Japan 2. Department of Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan 3. Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan 4. Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan 5. Department of Diagnostic Pathology, Graduate School of Medicine, Kyoto University, Kyoto, Japan 6. Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan 7. Department of Gastroenterology and Medicine, Fukuoka University School of Medicine, Fukuoka, Japan 8. Department of Hepato-Pancreatic-Biliary and Breast Surgery, Ehime University Graduate School of Medicine, Ehime, Japan 9. Department for the Promotion of Regional Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan 10. Shiga Medical University, Shiga, Japan 11. Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Background: The Japanese Liver Transplantation Society (JLTS), a cooperative research consortium, was established in 1980 in order to characterize and follow trends in patient characteristics and graft survival among all liver transplant patients in Japan. This study analyzed factors that may affect the current outcomes of pediatric patients who undergo LT by evaluating one of the largest pediatric LT cohorts in the world.

Methods: Between November 1989 and December 2018, 3347 pediatric patients underwent LT in Japan. Read More

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January 2021

Intra-articular silencing of periostin via nanoparticle-based siRNA ameliorates post-traumatic osteoarthritis in mice.

Arthritis Rheumatol 2021 May 13. Epub 2021 May 13.

Department of Orthopaedic Surgery, Musculoskeletal Research Center, Washington University, School of Medicine, St. Louis, MO, United States.

Objective: Recent evidence delineates an emerging role of Periostin (Postn) in osteoarthritis (OA) as its expression subsequent to knee injury is detrimental to the articular cartilage. We hypothesize that intra-articular knockdown of Postn in a murine model of post-traumatic OA would ameliorate OA.

Methods: Post-traumatic OA was induced in 10-week-old male C57BL/6J mice (n=24) by destabilization of the medial meniscus (DMM) and analyzed 8-week post-surgery. Read More

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Management of cervicofacial lymphatic malformations requires a multidisciplinary approach.

J Pediatr Surg 2021 May 30;56(5):1062-1067. Epub 2020 Sep 30.

Division of Pediatric Surgery, Department of Surgery, Children's Hospital Los Angeles, 4650 Sunset Blvd., MS#100, Los Angeles, CA, USA 90027; Department of Surgery, Keck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA, USA 90089. Electronic address:

Background/purpose: Cervicofacial lymphatic malformations (CFLM) are rare, potentially life-threatening vascular anomalies, yet reports on multidisciplinary treatment strategies are lacking. We evaluated outcomes for CFLMs following sclerotherapy, surgical resection, and/or medical management.

Methods: We identified children with a CFLM at a vascular anomalies center from 2004 to 2019. Read More

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Gut microbiota and its diet-related activity in children with intestinal failure on long-term parenteral nutrition.

JPEN J Parenter Enteral Nutr 2021 May 13. Epub 2021 May 13.

Department of Pediatric Gastroenterology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.

Background: This study characterized the gut microbiota and its diet-related metabolic activity in children with intestinal failure (IF) on parenteral nutrition (PN) compared with healthy controls and in relation to disease characteristics.

Methods: Serial fecal samples were collected from 15 IF patients (n = 68) and from 25 healthy children (n = 25). The fecal microbiota, and short chain fatty acids (SCFA) were measured. Read More

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Associations Between Prenatal, Perinatal, and Early Childhood Vitamin D Status and Risk of Dental Caries at 6 Years.

J Nutr 2021 May 12. Epub 2021 May 12.

The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands.

Background: Previous studies have suggested that insufficient concentrations of vitamin D are associated with dental caries in primary teeth, but evidence remains inconclusive.

Objectives: We assessed the longitudinal associations between prenatal, perinatal, and early childhood serum 25-hydroxyvitamin D concentrations [25(OH)D] and the risk of dental caries in 6-year-old children.

Methods: This research was conducted within the Generation R Study, a large, multi-ethnic, prospective cohort study located in Rotterdam, the Netherlands. Read More

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Methylphenidate treatment for cognitive symptoms associated with ADHD in a pediatric epilepsy patient following resection of a left frontal cortical dysplasia.

Epilepsy Behav Rep 2021 10;16:100435. Epub 2021 Feb 10.

Center for Rare Neurological Diseases, Atlanta, GA, USA.

We present data on a 10-year-old patient with drug-resistant epilepsy who was treated with methylphenidate for symptoms of attention deficit hyperactivity disorder (ADHD) that developed after she underwent surgical resection of a left frontal cortical dysplasia. . The patient's parents reported methylphenidate was helpful in improving their child's reading performance. Read More

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February 2021

Ophthalmological findings in children with non-syndromic craniosynostosis: preoperatively and postoperatively up to 12 months after surgery.

BMJ Open Ophthalmol 2021 26;6(1):e000677. Epub 2021 Apr 26.

Department of Neuroscience/Ophthalmology, Uppsala University, Uppsala, Sweden.

Aims: Craniosynostosis is a congenital condition characterised by premature fusion of one or more cranial sutures. The aim of this study was to analyse ophthalmic function before and after cranial surgery, in children with various types of non-syndromic craniosynostosis.

Methods: Children referred to Uppsala University Hospital for surgery of non-syndromic craniosynostosis were examined preoperatively. Read More

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Systematic profiling of ferroptosis gene signatures predicts prognostic factors in esophageal squamous cell carcinoma.

Mol Ther Oncolytics 2021 Jun 20;21:134-143. Epub 2021 Feb 20.

Department of Thoracic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.

We developed a predictive model associated with ferroptosis to provide a more comprehensive view of esophageal squamous cell carcinoma (ESCC) immunotherapy. Gene expression data and corresponding clinical outcomes were obtained from the GEO and The Cancer Genome Atlas (TCGA) databases, and a ferroptosis-related gene set was obtained from the FerrDb database. We identified 45 ferroptosis-related genes that were differentially expressed, including enrichment in genes involved in the immune system process. Read More

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Predictors of 90-Day Mortality following Hepatic Resection for Hepatocellular Carcinoma.

Visc Med 2021 Mar 27;37(2):102-109. Epub 2020 Oct 27.

Hepato-Pancreatico-Biliary Surgery, Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.

Background/purpose: 90-day mortality is a key performance indicator for short-term perioperative outcome of hepatic resection (HR). Although many preoperative, intraoperative, and postoperative variables predict 90-day mortality following elective HR, only few are specific to hepatocellular carcinoma (HCC). This study aims to determine the predictors of 90-day mortality following elective HR for HCC. Read More

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Ultra-High-Frequency Ultrasound in the Evaluation of Paediatric Pilomatricoma Based on the Histopathologic Classification.

Front Med (Lausanne) 2021 26;8:673861. Epub 2021 Apr 26.

Institute of Biomedical Engineering, Chinese Academy of Medical Sciences, Tianjin, China.

Pilomatricoma (PM) is one of the most common benign tumours in children. However, the inaccuracy of preoperative diagnosis and evaluation is high. Non-invasive examinations, including dermoscopy and ultrasound are helpful for diagnosing and evaluating PM. Read More

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Common and Rare Histological Variants of Hepatoblastoma in Children: A Pathological Diagnosis and Review of the Literature.

Gastrointest Tumors 2021 Apr 4;8(2):41-46. Epub 2021 Feb 4.

Department of Radiology, All India Institute of Medical Sciences, Jodhpur, India.

Hepatoblastoma (HB) is a rare tumor, but it is the most common primary liver malignancy in children and comprised of approximately 1% of all pediatric malignancies. Mostly, this tumor is sporadic in nature but can show a syndrome association. Upregulation in Wnt/β-catenin pathway can be there in 70-80% cases of HB. Read More

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Antimeningococcal Vaccination Coverage Among Healthcare Workers in an Italian University Hospital.

Front Public Health 2021 26;9:651100. Epub 2021 Apr 26.

School of Specialization in Occupational Medicine, University of Pisa, Pisa, Italy.

Following an outbreak of meningococcal epidemic in 2015 and 2016 in Tuscany, we registered a higher demand for antimeningococcal vaccination (anti-Men ACWY) by Healthcare Workers of the University Hospital of Pisa [Azienda Ospedaliero Universitaria Pisana (AOUP)]. The purpose of this work is to analyze and discuss data on vaccination coverage resulting from this vaccination campaign. We conducted a monocentric study about anti-Men vaccination in the healthcare workers of the AOUP following the outbreak of meningococcal meningitis that occurred mainly in the population of the Tuscan provinces of Pisa, Pistoia, Prato, and Florence. Read More

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Stress Hyperglycemia in Children and Adolescents as a Prognostic Indicator for the Development of Type 1 Diabetes Mellitus.

Front Pediatr 2021 26;9:670976. Epub 2021 Apr 26.

Second Department of Internal Medicine and Research Institute, Medical School, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Hyperglycemia is a common manifestation in the course of severe disease and is the result of acute metabolic and hormonal changes associated with various factors such as trauma, stress, surgery, or infection. Numerous studies demonstrate the association of adverse clinical events with stress hyperglycemia. This article briefly describes the pathophysiological mechanisms which lead to hyperglycemia under stressful circumstances particularly in the pediatric and adolescent population. Read More

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Implementation of Supine Percutaneous Nephroscopic Surgery to Remove an Upward Migration of Ureteral Catheter in Infancy: A Case Report.

Res Rep Urol 2021 5;13:215-219. Epub 2021 May 5.

Division of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.

Background: Double-J stents are favorably utilized after pyeloplasty. In rare situations, the stent may migrate upward. Here, we demonstrate the implementation and result of a supine percutaneous nephroscopic surgery (PNS) to retrieve a proximately migrated ureteral catheter in a pediatric patient. Read More

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Subcutaneous Sacro Coccygeal Myxopapillary Ependymoma: A Case Report and a Comprehensive Review of the Literature Reappraising Its Current Diagnostic Approach and Management.

Cureus 2021 May 10;13(5):e14931. Epub 2021 May 10.

Radiation Oncology, Civil hospital Shillong, Shillong, IND.

Sacrococcygeal myxopapillary ependymoma (MPE) is an uncommon type I glial tumor detected most frequently in the lumbosacral area of adolescents and children. It is usually presented as an intradural ependymal tumor that originates from the filum terminale and other locations within the ventricular system along the craniospinal axis. In rare cases, however, MPE may develop as a primary subcutaneous tumor in the sacrococcygeal area. Read More

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Corrigendum to "A Case Report of Complete Resolution of Auricular Mucormycosis in an 18-Month-Old Diabetic Child".

Case Rep Otolaryngol 2021 17;2021:9794624. Epub 2021 Apr 17.

Department of Otology, Neurotology and Cochlear Implant Surgery, Program Director of the Saudi Board of Otolaryngology, Ohud Hospital, Al Madinah Almunwarah, Madinah, Saudi Arabia.

[This corrects the article DOI: 10.1155/2021/6618191.]. Read More

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Specific aspects of tympanoplasty in children: A retrospective cohort study of 95 cases.

Ann Med Surg (Lond) 2021 May 19;65:102297. Epub 2021 Apr 19.

ENT Department, Face and Neck Surgery, Hospital August, 20'1953, University Hospital Center IBN ROCHD, Hassan II University, Casablanca, Morocco.

Background: Paediatric tympanoplasty is now a common surgical procedure. The age from which it could be proposed varies regarding children specificities such as Eustachian tube dysfunction, the high incidence of upper airway infections and the immaturity of the immune system. The aim of this study is to describe the specific constitutional, epidemiological and operative aspects as well as the anatomical and functional results of tympanoplasty in children. Read More

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Modified surgical reconstruction technique for a rare isolated congenital sternal cleft: In a six -year-old child.

Ann Med Surg (Lond) 2021 May 14;65:102280. Epub 2021 Apr 14.

Department of Surgical Specialties, Maternity and Children Hospital, Dammam, Saudi Arabia.

We report the modified surgical reconstruction technique for correction for a large isolated congenital sternal cleft in 6 years old girl using a methyl methacrylate marlex mesh sandwich plate (MMS). The patient was referred to our tertiary care institution with a sizeable anterior chest wall bony defect. There was a large bulging under the skin due to protrusion of mediastinal viscera and visible cardiac pulsations with breathing. Read More

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The Effects of Ondansetron on the Analgesic Action of Intravenous Acetaminophen after Tonsillectomy in Children: A Triple-Blind Randomized Controlled Trial.

Oxid Med Cell Longev 2021 23;2021:6611740. Epub 2021 Apr 23.

Department of Community Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Introduction: Severe pain, nausea, and vomiting after tonsillectomy surgery are among the issues that not only affect patient satisfaction but also may result in complications and delay patient discharge. This study was conducted to assess the effect of intravenous administration of ondansetron on the analgesic action of intravenous acetaminophen after tonsillectomy in children. . Read More

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Dexmedetomidine Protects Against Septic Liver Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT1 Signaling Pathway.

Front Pharmacol 2021 26;12:658677. Epub 2021 Apr 26.

Department of Intensive Care Unit, Children's Hospital of Chongqing Medical University, Chongqing, China.

Liver injury is one of the serious complications of sepsis. Previous studies suggested that dexmedetomidine (DEX) could alleviate cecal ligation and puncture (CLP)-induced liver injury. However, it is unclear whether the protective effect of DEX on sepsis-induced liver injury is related to autophagy. Read More

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