449,726 results match your criteria surface analysis

One-step Electrodeposition of CuSCN/CuI Nanocomposite and Its Hole Transport-Ability in Inverted Planar Perovskite Solar Cells.

Nanotechnology 2021 May 5. Epub 2021 May 5.

Energy Science, Alagappa University, Science Block, Karaikudi, Tamilnadu, 630003, INDIA.

The synthesis of CuSCN/CuI nanocomposite by single-step electrodeposition is developed. The surface morphology and film thickness are controlled by changing the electrochemical potential and deposition time. The mixed-phase formation of CuSCN/CuI is confirmed through X-ray diffraction and Raman spectral analysis. Read More

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Efficient solar light facilitated photo-oxidative detoxification of gaseous 2-chloroethyl ethyl sulfide on ZrO-doped g-CN under dry and humid air.

Chemosphere 2021 Apr 27;280:130685. Epub 2021 Apr 27.

Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, 03722, Republic of Korea. Electronic address:

Photo-oxidation of chemical warfare agents is considered a promising strategy to cope with threats from accidental or intentional release. In this study, heterostructure photocatalysts comprising different amounts of zirconium oxide (ZrO) over carbon nitride (CN) were synthesized via simple thermal exfoliation, followed by a precipitation method. The successful photocatalytic detoxification activity of the as-prepared photocatalyst was analyzed against 2-chloroethyl ethyl sulfide (CEES) under simulated solar light and natural sunlight irradiation in dry and humid air. Read More

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Outdoor human decomposition in Sweden: A retrospective quantitative study of forensic-taphonomic changes and postmortem interval in terrestrial and aquatic settings.

J Forensic Sci 2021 May 5. Epub 2021 May 5.

Division of Forensic Medicine in Linköping, National Board of Forensic Medicine, Linköping, Sweden.

This paper presents a quantitative retrospective study of gross human decomposition in central and southeastern Sweden. The applicability of methods developed abroad for postmortem interval (PMI) estimation from decomposition morphology and temperature are is evaluated. Ninety-four cases were analyzed (43 terrestrial and 51 aquatic) with a median PMI of 48 days. Read More

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Role of Marginal Ridge Shape and Contact Extent in Proximal Caries Between Primary Molars.

J Clin Pediatr Dent 2021 Apr;45(2):98-103

Objectives: To determine different combinations of marginal ridge shape (MRS) and contact extents in nature of the contact between primary molars and its correlation with the presence of carious lesions on radiographic examination of approximal surfaces.

Study Design: Retrospective study of 347 clinical records, including photographs and bitewing radiographs, were assessed for intact MRS and caries extent. The carious lesions were scored (0-5, Mejàre scoring system) radiographically and correlated to the intact MRS on clinical photographs, and strength of associations quantified using logistic regression analysis and chi-square tests. Read More

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Machine learning for reparameterization of four-site water models: TIP4P-BG and TIP4P-BGT.

Phys Chem Chem Phys 2021 May 14;23(17):10164-10173. Epub 2021 Apr 14.

International Research Center for Computational Mechanics, State Key Laboratory of Structural Analysis for Industrial Equipment, Department of Engineering Mechanics, Faculty of Vehicle Engineering and Mechanics, Dalian University of Technology, Dalian 116024, P. R. China.

Parameterizing an effective water model is a challenging issue because of the difficulty in maintaining a comprehensive balance among the diverse physical properties of water with a limited number of parameters. The advancement in machine learning provides a promising path to search for a reliable set of parameters. Based on the TIP4P water model, hence, about 6000 molecular dynamics (MD) simulations for pure water at 1 atm and in the range of 273-373 K are conducted here as the training data. Read More

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Sulfation of a FLAG tag mediated by SLC35B2 and TPST2 affects antibody recognition.

PLoS One 2021 5;16(5):e0250805. Epub 2021 May 5.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.

A FLAG tag consisting of DYKDDDDK is an epitope tag that is frequently and widely used to detect recombinant proteins of interest. In this study, we performed a CRISPR-based genetic screening to identify factors involved in the detection of a FLAG-tagged misfolded model protein at the cell surface. In the screening, SLC35B2, which encodes 3'-phosphoadenosine-5'-phosphosulfate transporter 1, was identified as the candidate gene. Read More

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The research for the function evaluation of facial nerve and the mechanisms of rehabilitation training.

Medicine (Baltimore) 2021 May;100(18):e25430

Guangzhou University of Chinese Medicine, Guangzhou, China.

Background: Peripheral facial paralysis (PFP) is a common peripheral neural disease. Acupuncture treatment combined with PFP rehabilitation exercises is a routine method of PFP treatment. This article is to provide a new visual and objective evaluation method for exploring the mechanism and efficacy of acupuncture treatment on PFP, and develop an interactive augmented facial nerve function rehabilitation training system with multiple training models. Read More

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Analytical approach for lubricant characterization of excipients using the surface replication method.

Drug Dev Ind Pharm 2021 May 5:1-20. Epub 2021 May 5.

Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku 422-8526, Japan.

Lubricants are indispensable pharmaceutical ingredients for preventing tableting failure due to powder adhesion to the die wall. The impact of lubricants was evaluated with use of the Binding Identification for Net Detriment (BIND) surface replication method. Raloxifene hydrochloride (RH) was selected as a model chemical with high adhesion, and four commercially available tablet lubricants - stearic acid, sodium stearyl fumarate, calcium stearate and magnesium stearate - were used for RH formulation. Read More

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Reversing the Humidity Response of MoS- and WS-Based Sensors Using Transition-Metal Salts.

ACS Appl Mater Interfaces 2021 May 5. Epub 2021 May 5.

Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193 Barcelona, Spain.

Two-dimensional materials, such as transition-metal dichalcogenides (TMDs), are attractive candidates for sensing applications due to their high surface-to-volume ratio, chemically active edges, and good electrical properties. However, their electrical response to humidity is still under debate and experimental reports remain inconclusive. For instance, in different studies, the impedance of MoS-based sensors has been found to either decrease or increase with increasing humidity, compromising the use of MoS for humidity sensing. Read More

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Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments.

ACS Infect Dis 2021 May 5. Epub 2021 May 5.

Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.

Fragment screening is a powerful drug discovery approach particularly useful for enzymes difficult to inhibit selectively, such as the thiol/selenol-dependent thioredoxin reductases (TrxRs), which are essential and druggable in several infectious diseases. Several known inhibitors are reactive electrophiles targeting the selenocysteine-containing C-terminus and thus often suffering from off-target reactivity . The lack of structural information on the interaction modalities of the C-terminus-targeting inhibitors, due to the high mobility of this domain and the lack of alternative druggable sites, prevents the development of selective inhibitors for TrxRs. Read More

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Platelet Immunophenotyping by High-Dimensional Mass Cytometry.

Curr Protoc 2021 May;1(5):e112

Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts.

Platelets are small blood cells that contribute to hemostasis, immunity, and inflammation. Characterization of platelet surface markers allows for differentiation of activated platelets from resting platelets, diagnosis of platelet disorders, and investigation of platelet biology and pathology. In this article, we describe the use of mass cytometry or "CyTOF" (mass spectroscopy detection of metal-tagged antibodies on individual cells) to measure a large number of markers on each platelet and to identify platelet subsets based on the shared expression of multiple markers. Read More

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Extraction and electrochemical detection for quantification of trace-level DNA.

Mikrochim Acta 2021 May 5;188(6):180. Epub 2021 May 5.

Center of Excellence for Trace Analysis and Biosensor, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand.

A novel strategy was developed to extract, detect, and quantify trace-level DNA. For the extraction step, a composite of methylene blue (MB), poly(acrylic acid) (PAA), and modified iron oxide magnetic nanoparticles (IOMNPs) (PAA/IOMNPs) was used to adsorb DNA from the sample. MB-PAA/IOMNPs with adsorbed DNA were then separated from the solution with an external magnet and MB-DNA was eluted from PAA/IOMNPs with acetic acid. Read More

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CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface TLR9 to enhance the antibody response to vaccine.

Appl Microbiol Biotechnol 2021 May 5. Epub 2021 May 5.

Department of Molecular Biology in College of Basic Medical Sciences and Institute of Pediatrics in The First Hospital of Jilin University, Jilin University, Changchun, Jilin, 130021, People's Republic of China.

The surface Toll-like receptor 9 (sTLR9) has been identified on the surface of the B cells and was presumed to be a negative regulator of B cell responses. CpG ODN, a TLR9 agonist, has been successfully used as an adjuvant of hepatitis B vaccine to enhance antibody responses. However, it is unknown whether the sTLR9 is involved in regulating the activation and maturation of B cells in the antibody responses induced by CpG ODN-adjuvanted vaccines. Read More

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Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis.

JAMA Psychiatry 2021 May 5. Epub 2021 May 5.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.

Importance: The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological markers of psychosis risk.

Objective: To investigate baseline structural neuroimaging differences between individuals at CHR and healthy controls as well as between participants at CHR who later developed a psychotic disorder (CHR-PS+) and those who did not (CHR-PS-).

Design, Setting, And Participants: In this case-control study, baseline T1-weighted magnetic resonance imaging (MRI) data were pooled from 31 international sites participating in the ENIGMA Clinical High Risk for Psychosis Working Group. Read More

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An experimental investigation of light emission produced in the process of positronium formation in matter.

Phys Chem Chem Phys 2021 May 5. Epub 2021 May 5.

Institut für Strahlenphysik/Institute of Radiation Physics, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstr. 400, 01328 Dresden, Germany.

The excess energy emitted during the positronium (Ps) formation in condensed matter may be released as light. Spectroscopic analysis of this light can be a new method of studying the electronic properties of materials. We report the first experimental attempt, according to our knowledge, to verify the existence of this emission process. Read More

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Elastic Rayleigh-Plateau instability: dynamical selection of nonlinear states.

Soft Matter 2021 May 5. Epub 2021 May 5.

Physics of Fluids Group, Faculty of Science and Technology, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands.

A slender thread of elastic hydrogel is susceptible to a surface instability that is reminiscent of the classical Rayleigh-Plateau instability of liquid jets. The final, highly nonlinear states that are observed in experiments arise from a competition between capillarity and large elastic deformations. Combining a slender analysis and fully three-dimensional numerical simulations, we present the phase map of all possible morphologies for an unstable neo-Hookean cylinder subjected to capillary forces. Read More

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A UHV MOKE magnetometer complementing XMCD-PEEM at the Elettra Synchrotron.

J Synchrotron Radiat 2021 May 30;28(Pt 3):995-1005. Epub 2021 Mar 30.

Elettra-Sincrotrone Trieste SCpA, Basovizza, Trieste, Italy.

We report on a custom-built UHV-compatible Magneto-Optical Kerr Effect (MOKE) magnetometer for applications in surface and materials sciences, operating in tandem with the PhotoEmission Electron Microscope (PEEM) endstation at the Nanospectroscopy beamline of the Elettra synchrotron. The magnetometer features a liquid-nitrogen-cooled electromagnet that is fully compatible with UHV operation and produces magnetic fields up to about 140 mT at the sample. Longitudinal and polar MOKE measurement geometries are realized. Read More

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A refraction correction for buried interfaces applied to in situ grazing-incidence X-ray diffraction studies on Pd electrodes.

J Synchrotron Radiat 2021 May 15;28(Pt 3):919-923. Epub 2021 Mar 15.

SUNCAT Center for Interface Science and Catalysis, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

In situ characterization of electrochemical systems can provide deep insights into the structure of electrodes under applied potential. Grazing-incidence X-ray diffraction (GIXRD) is a particularly valuable tool owing to its ability to characterize the near-surface structure of electrodes through a layer of electrolyte, which is of paramount importance in surface-mediated processes such as catalysis and adsorption. Corrections for the refraction that occurs as an X-ray passes through an interface have been derived for a vacuum-material interface. Read More

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Chronic suppurative otitis media with cholesteatoma and chronic otitis media with granulation by scanning electron microscopy based on analysis of 140 patients.

Otolaryngol Pol 2021 Feb;75(3):1-5

Chair Otolaryngology of the Jagiellonian University Collegium Medicum, Cracow, Poland.

Objectives Chronic purulent cholesteatoma of the middle ear, as well as to a lesser extent chronic granulomatous otitis media, lead to destruction of bone structures within the middle ear space. Above process is controlled by the OPG/RANKL/RANK system. Material and methods An analysis of 140 patients operated on due to chronic otitis media was performed. Read More

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February 2021

In Situ Determination of Sialic Acid on Cell Surface with a pH-Regulated Polymer Enzyme Nanoreactor.

Anal Chem 2021 May 5. Epub 2021 May 5.

Beijing National Laboratory for Molecular Sciences; Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.

Sialic acid (SA) is an important monosaccharide that is involved in incurable cancer immunotherapy. However, it is difficult to detect SA in situ using the existing strategy based on the SA-terminated glycopeptide extraction from the cell lysate. The countermeasures of the bottleneck caused by cell disruption and peptide extraction should be designed based on a "cell-surface attachment and controlled enzymolysis" protocol. Read More

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Lubricant-Infused Surfaces for Low-Surface-Tension Fluids: The Extent of Lubricant Miscibility.

ACS Appl Mater Interfaces 2021 May 5. Epub 2021 May 5.

Department of Mechanical Science and Engineering, University of Illinois, Urbana, Illinois 61801, United States.

Lubricant-infused surfaces (LISs) and slippery liquid-infused porous surfaces (SLIPSs) have shown remarkable success in repelling low-surface-tension fluids. The atomically smooth, defect-free slippery surface leads to reduced droplet pinning and omniphobicity. However, the presence of a lubricant introduces liquid-liquid interactions with the working fluid. Read More

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Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values, and antioxidant activity of shiitake mushroom.

J Sci Food Agric 2021 May 5. Epub 2021 May 5.

Department of Traditional Chinese Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China.

Background: Shiitake mushroom is one of the most popular delicious vegetables, but fresh shiitake mushroom has short shelf life due to biochemical degradation. Drying can prolong the shelf life of mushroom. Additionally, application of cold plasma pretreatments (CPT) before drying can preserve the product quality, processing cost, and nutritional values. Read More

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The C(P) + O(Σ) → CO ↔ CO(Σ) + O(D)/O(P) reaction: thermal and vibrational relaxation rates from 15 K to 20 000 K.

Phys Chem Chem Phys 2021 May 5. Epub 2021 May 5.

Department of Chemistry, University of Basel, Klingelbergstrasse 80, CH-4056 Basel, Switzerland. and Brown University, Providence, RI 02912, USA.

Thermal rates for the C(3P) + O2(3Σg-) ↔ CO(1Σ+)+ O(1D)/O(3P) reaction are investigated over a wide temperature range based on quasi classical trajectory (QCT) simulations on 3-dimensional, reactive potential energy surfaces (PESs) for the 1A', (2)1A', 1A'', 3A' and 3A'' states. These five states are the energetically low-lying states of CO2 and their PESs are computed at the MRCISD+Q/aug-cc-pVTZ level of theory using a state-average CASSCF reference wave function. Analysis of the different electronic states for the CO2 → CO + O dissociation channel rationalizes the topography of this region of the PESs. Read More

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Combining vancomycin-modified gold nanorod arrays and colloidal nanoparticles as a sandwich model for the discrimination of Gram-positive bacteria and their detection surface-enhanced Raman spectroscopy (SERS).

Analyst 2021 May 4. Epub 2021 May 4.

East Anatolia High Technology Application and Research Center (DAYTAM), Ataturk University, 25240 Erzurum, Turkey. and Department of Chemical Engineering, Ataturk University, 25240 Erzurum, Turkey and Department of Nanoscience and Nanoengineering, Ataturk University, 25240 Erzurum, Turkey.

This study reports the development of a highly sensitive antibiotic-based discrimination and sensor platform for the detection of Gram-positive bacteria through surface-enhanced Raman spectroscopy (SERS). Herein, a combination of gold nanorod arrays (GNAs) and colloidal gold nanoparticles (AuNPs) was used as a SERS platform. To specifically capture Gram-positive bacteria, both GNAs and AuNPs were functionalized with thiol-modified vancomycin (HS-Van) molecules. Read More

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-MagnetoMethyl IP: a magnetic nanoparticle-mediated immunoprecipitation and electrochemical detection method for global DNA methylation.

Analyst 2021 May 5. Epub 2021 May 5.

Queensland Micro- and Nanotechnology Centre (QMNC), Griffith University, Nathan Campus, QLD 4111, Australia. and School of Environment and Science (ESC), Griffith University, Nathan Campus, QLD 4111, Australia.

The quantification of global 5-methylcytosine (5mC) content has emerged as a promising approach for the diagnosis and prognosis of cancers. However, conventional methods for the global 5mC analysis require large quantities of DNA and may not be useful for liquid biopsy applications, where the amount of DNA available is limited. Herein, we report magnetic nanoparticles-assisted methylated DNA immunoprecipitation (e-MagnetoMethyl IP) coupled with electrochemical quantification of global DNA methylation. Read More

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Polymer-capped CdSe/ZnS quantum dots for the sensitive detection of Cu and Hg and the quenching mechanism.

Anal Methods 2021 May 4. Epub 2021 May 4.

Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, School of Chemistry, South China Normal University, Guangzhou 510006, People's Republic of China.

In this work, poly(styrene-co-maleic anhydride)-capped CdSe/ZnS quantum dots (QDs) aminolyzed with ethanolamine are proposed as fluorescent probes for the detection of Cu2+ and Hg2+, and two different quenching mechanisms are discussed in detail. The coordination abilities of the surface polymer of CdSe/ZnS QDs and two metal ions are calculated by density functional theory (DFT). The photoinduced electron transfer from excited QDs to Cu2+ unoccupied orbitals is enhanced due to the coordination between Cu2+ and the surface polymer of QDs. Read More

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Click preparation of multiple-thioether bridged cyclodextrin chiral materials for efficient enantioseparation in high-performance liquid chromatography.

Analyst 2021 May;146(9):3025-3033

School of Science, Tianjin Key Laboratory of Molecular Optoelectronic Science, Department of Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin University, Tianjin 300072, P. R. China.

A highly efficient covalent immobilization procedure is considered as an essential tool for obtaining stable and reliable cyclodextrin (CD) chiral stationary phases (CSPs). This work reports the "thiolene" click immobilization of heptakis(6-mercapto-6-deoxy)-β-CD-CSP onto alkene functional silica to afford novel multiple-thioether bridged CD CSPs by controlling the surface CD concentration. Solid-state NMR, FTIR, TGA and X-ray photoelectron diffraction spectroscopy (XPS) results proved the successful preparation of the desired CSPs with different surface CD loadings. Read More

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A sequentially bioconjugated optofluidic laser for wash-out-free and rapid biomolecular detection.

Lab Chip 2021 May;21(9):1686-1693

Key Laboratory of Optical Fiber Sensing and Communications (Ministry of Education of China), School of Information and Communication Engineering, University of Electronic Science and Technology of China, No. 2006, Xiyuan Ave., Chengdu, 611731 China.

Microstructures can improve both sensitivity and assay time in heterogeneous assays (such as ELISA) for biochemical analysis; however, it remains a challenge to perform the essential wash process in those microstructure-based heterogeneous assays. Here, we propose a sequential bioconjugation protocol to solve this problem and demonstrate a new type of fiber optofluidic laser for biosensing. Except for acting as an optical microresonator and a microstructured substrate, the miniaturized hollow optical fiber (HOF) is used as a microfluidic channel for storing and transferring reagents thanks to its capability in length extension. Read More

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The α-D-anomer of 2'-deoxycytidine: crystal structure, nucleoside conformation and Hirshfeld surface analysis.

Acta Crystallogr C Struct Chem 2021 May 9;77(Pt 5):202-208. Epub 2021 Apr 9.

Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.

β-2'-Deoxyribonucleosides are the constituents of nucleic acids, whereas their anomeric α-analogues are rarely found in nature. Moreover, not much information is available on the structural and conformational parameters of α-2'-deoxyribonucleosides. This study reports on the single-crystal X-ray structure of α-2'-deoxycytidine, CHNO (1), and the conformational parameters characterizing 1 were determined. Read More

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The oral microbiome in early rheumatoid arthritis patients and individuals at risk differs from healthy controls.

Arthritis Rheumatol 2021 May 4. Epub 2021 May 4.

Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry of Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objective: It has been suggested that rheumatoid arthritis (RA) may originate at the oral mucosa. Our aim was to assess the oral microbiome and the periodontal condition in patients with early rheumatoid arthritis (ERA) and individuals at risk of RA.

Methods: Three groups were recruited (50 participants each): (1) ERA patients (2010 ACR/EULAR criteria), (2) at-risk individuals (arthralgia and autoantibodies), and (3) healthy controls. Read More

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