World J Gastroenterol 2016 Jan;22(1):379-93
Kornélia Baghy, Péter Tátrai, Eszter Regős, Ilona Kovalszky, First Department of Pathology and Experimental Cancer Research, Semmelweis University, H1085 Budapest, Hungary.
Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain, such as a heparan, dermatan, chondroitin, or keratan sulfate, covalently attached to the protein core. These molecules are categorized based on their structure, localization, and function, and can be found in the extracellular matrix, on the cell surface, and in the cytoplasm. Cell-surface heparan sulfate proteoglycans, such as syndecans, are the primary type present in healthy liver tissue. Read More