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Rev Med Chil 2020 Nov;148(11):1674-1678

Grupo Medicina Hospitalaria, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

In patients with actively bleeding gastric varices, the treatment of choice is the endoscopic use of sclerosing agents such as cyanoacrylate. We report a 69-year-old man who, after being treated with cyanoacrylate, suffered from recurrent febrile episodes. After an extensive study and broad-spectrum antibiotic treatment, discarding other presumably infectious focus, the superinfection of the cyanoacrylate plug was suspected, and its surgical removal was decided. Read More

World J Plast Surg 2021 Jan;10(1):30-36

Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt.

Background: We aimed to review the treatment and outcome of patients' undergone reconstruction of large full thickness scalp defects with exposed calvarium after oncologic resection with the combined local flap and split-thickness skin graft (STSG) technique.

Methods: A retrospective review of 45 patients with scalp defects secondary to tumor extirpation was performed at the Plastic Surgery Department, Tanta University Hospital, Tanta, Egypt from Nov 2016 to Nov 2019. Patients, with large (>50 cm2) and full-thickness (exposed calvarium) scalp defects, who underwent scalp reconstruction with the combined local flap and STSG technique and had completed their medical records were enrolled. Read More

Int J Cardiol 2021 Apr 5. Epub 2021 Apr 5.

School of Medicine, National Yang Ming University, Taipei, Taiwan; National Yang Ming Chiao Tung University, Taipei, Taiwan; Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address:

Objective: Patients diagnosed of DeBakey type III aortic dissection with partial thrombosis of false lumen (FL) have a higher mortality rate. However, IIIb dissections with full patent FL tend to exhibit a partially thrombosed FL quickly after thoracic endovascular aortic repair (TEVAR); thus, we investigated survival and aortic remodeling in this population.

Methods: We reviewed computed tomography aortograms (CTAs) of 123 patients with TEVAR-treated IIIb aortic dissections from July 2006 to June 2015; contrast density of CTAs represented intraluminal flow. Read More

Afr Dev Rev 2021 Mar 2. Epub 2021 Mar 2.

Pan-African Scientific Research Council, Department of Economics Yaoundé University of Dschang Dschang Cameroon.

This paper analyzes the impacts of the Covid-19 pandemic on employment in Cameroon. Using data collected from a rapid survey led by the National Institute of Statistics, on a sample of 1,310 respondents from April to May 2020. These data show that a large proportion of workers suffered a wage cut (60. Read More

J Pediatr Urol 2021 Mar 19. Epub 2021 Mar 19.

Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark. Electronic address:

Introduction And Aim Of The Study: Most treatments of nocturnal enuresis (NE) are targeting the main pathophysiological mechanisms, i.e., excess nocturnal urine production, bladder reservoir dysfunction and inability to awaken to a full bladder. Read More

J Clin Med 2021 Mar 2;10(5). Epub 2021 Mar 2.

Clinic of Psychosomatic Medicine and Psychotherapy, Medical University of Ulm, 89081 Ulm, Germany.

Background: Stress and depression are known to contribute to coronary artery disease (CAD) with catecholamines (CA), altering the balance to a pro- and anti-inflammatory stetting and potentially playing a key role in the underlying pathophysiology. This study aimed to elucidate the impact of social stress on the CA system and inflammation markers in patients suffering from CAD and depression.

Methods: 93 subjects were exposed to the Trier Social Stress Test (TSST). Read More

ANZ J Surg 2021 Apr 1. Epub 2021 Apr 1.

Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul National University Hospital, Seoul, South Korea.

Background: Severe burn scar contracture of the extremities, especially the joint areas, causes aesthetic problems and functional limitation. Release of burn scar contractures requires complete removal of the scars and resurfacing of the resulting defects. Here, we describe thoracodorsal artery perforator (TDAP) free flaps for reconstructing burn scar contractures. Read More

Case Rep Oncol 2021 Jan-Apr;14(1):232-238. Epub 2021 Mar 1.

Division of Hematology-Oncology, Department of Internal Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan.

Anti-epithelial growth factor receptor or anti-vascular endothelial growth factor agents combined with chemotherapy were the standard of treatment for metastatic colorectal cancer (CRC). However, increasing evidence of molecularly stratified treatment makes the complexity of treatment. Anaplastic lymphoma kinase (ALK) gene alternation is one of potential target for biomarker-guided therapy for CRC. Read More

J Clin Neurosci 2021 Apr 25;86:20-25. Epub 2021 Jan 25.

Department of Neurosurgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China.

Background: Studies have shown that microvascular decompression (MVD) surgery could improve the clinical symptoms of hemifacial spasm (HFS) and decrease the blood pressure (BP) in patients with refractory hypertension. More positive long-term results are required to establish MVD as a treatment option for high blood pressure (HBP) and to refine the patient selection criteria.

Methods: From October 2015 to September 2018, based on patient selection for cases with both HFS and poorly controlled HBP of nervous origin, MVD surgeries were performed on 12 patients aiming for better BP control. Read More

J Obstet Gynaecol Res 2021 Mar 24. Epub 2021 Mar 24.

Department of Public Health, Juntendo University Faculty of Medicine, Tokyo, Japan.

In recent decades, surgical techniques, new anticancer drugs' development, and radiation equipment have led to continuous improvements in cancer survival rates and quality of life of cancer survivors (CSs). While 61.0% of gynecological cancer survivors (GCS) in Japan belonged to a working-age group (20-64 years old), the number of working GCS within the working-age population has increased. Read More

Int J Prosthodont 2021 Mar 18. Epub 2021 Mar 18.

Purpose: To evaluate the survival rates and technical outcomes of minimally invasive full-mouth rehabilitations in patients affected by dental erosion and attrition.

Materials And Methods: For this retrospective study, 28 subjects (8 women, 20 men; mean age: 45.6 years) who suffered from generalized erosions and attrition and who were treated according to the 3-step technique were invited to participate. Read More

Ann Palliat Med 2021 Feb;10(2):2167-2174

Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

Background: In March 2020, the World Health Organization (WHO) declared COVID-19 a public health emergency of international concern. A small proportion of patients infected with COVID-19 go on to develop pneumonia. We speculated that COVID-19 may be likely to result in psychological disorders such as anxiety and depression. Read More

J BUON 2021 Jan-Feb;26(1):189-195

Department of Thyroid and Breast Surgery, Taizhou People's Hospital, Taizhou, China.

Purpose: To explore the efficacy and safety of 500 mg of fulvestrant for the postmenopausal patients with estrogen receptor (ER)-positive metastatic breast cancer, and to analyze the factors affecting the prognosis of patients.

Methods: A retrospective analysis was conducted on the clinical data of 86 postmenopausal patients with ER-positive metastatic breast cancer, who were admitted to our hospital from January 2015 to December 2016, and these patients were treated with 500 mg of fulvestrant. The clinical efficacy and incidence of adverse reactions were evaluated. Read More

Q J Exp Psychol (Hove) 2021 Mar 29:17470218211004385. Epub 2021 Mar 29.

Department of Linguistics and Modern Languages, The Chinese University of Hong Kong, Hong Kong, China.

In the past few decades, Chinese speakers have suffered from difficulties in handwriting, which include tip-of-the-pen (TOP) states (knowing a character but failing to fully handwrite it) and character amnesia in general (a general inability to handwrite a character despite being able to recognise it). The current study presents a systematic empirical investigation of the effects of character-level lexical characteristics and handwriter-level individual differences on TOP, character amnesia, and partial orthographic access in TOP states. Using a spelling-to-dictation task, we had 64 participants to handwrite 200 simplified Chinese characters. Read More

Ann Transl Med 2021 Feb;9(4):339

Department of Bone and Soft Tissue Tumor, Peking University Cancer Hospital, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Beijing, China.

Background: The goal of this study was to retrospectively analyze the efficacy and safety of pembrolizumab in the real-world treatment of soft tissue sarcoma (STS).

Methods: We analyzed 38 patients who suffered from STS and received pembrolizumab treatment from July 2017 to December 2018 in our hospital. We investigated the influence of clinical characteristics, treatment timing, and treatment protocol on objective response rate (ORR). Read More

Zhonghua Shao Shang Za Zhi 2021 Mar 3;37(3):1-7. Epub 2021 Mar 3.

Department of Burns, Beijing Jishuitan Hospital, Beijing 100035, China.

To investigate the clinical effect of staged repair strategy for chronic sacrococcygeal radiation ulcer. The retrospective cohort study method was applied. Twelve patients with sacrococcygeal radiation ulcer were admitted to Beijing Jishuitan Hospital from January 2010 to June 2020, including 7 males and 5 females with ages ranging from 38 to 74 years. Read More

Monaldi Arch Chest Dis 2021 03 9. Epub 2021 Mar 9.

Division of Cardiology, SS Trinità Borgomanero Hospital, ASL NO, Novara.

Pheochromocytoma is a rare adrenal tumor characterized by the secretion of catecholamines and vasoactive peptides. It can cause a catecholaminergic storm and lead to acute coronary syndromes. We present the case of a 53-year-old man, without any medical history, who arrived to the hospital following a spinal trauma due a fall. Read More

Qual Life Res 2021 Mar 8. Epub 2021 Mar 8.

Department of Health Economics, Corvinus University of Budapest, 8 Fővám tér, 1093, Budapest, Hungary.

Purpose: Eight of the ten items of the Dermatology Life Quality Index (DLQI) have a 'not relevant' response (NRR) option. There are two possible ways to interpret NRRs: they may be considered 'not at all' or missing responses. We aim to compare the measurement performance of the DLQI in psoriasis patients when NRRs are scored as '0' (hereafter zero-scoring) and 'missing' (hereafter missing-scoring) using Rasch model analysis. Read More

Health Res Policy Syst 2021 Mar 6;19(1):30. Epub 2021 Mar 6.

Swiss Tropical and Public Health Institute, P.O. Box, CH-4003, Basel, Switzerland.

Between 2014 and 2016, Switzerland's access to some of the EU funding was limited after a referendum against mass immigration was accepted and the country refused to sign the free movement accord to the EU's newest member, Croatia. It is well documented that Switzerland has suffered from a drop in participation, funding and a decrease in consortium lead positions. However, there is no account of the consequences on institutional level. Read More

iScience 2021 Mar 4;24(3):102142. Epub 2021 Feb 4.

Institute of Developmental Biology and Regenerative Medicine, Southwest University, 2 Tiansheng Road, Beibei, 400715 Chongqing, China.

Whether transdifferentiation of the biliary epithelial cells (BECs) to hepatocytes occurs under physiological conditions and contributes to liver homeostasis remains under long-term debate. Similar questions have been raised under pathological circumstances if a fibrotic liver is suffered from severe injuries. To address these questions in zebrafish, we established a sensitive lineage tracing system specific for the detection of BEC-derived hepatocytes. Read More

Medicine (Baltimore) 2021 Feb;100(8):e24896

Department of Cardiology, West China Hospital.

Introduction: Hemodynamically-instable ventricular arrhythmias (VAs) are rare in patients with pulmonary hypertension (PH). To the best of our knowledge, only 1 case has been reported so far. Moreover, the pathogenesis of this kind of arrhythmia remains obscured and its treatment is challenging. Read More

Ann Plast Surg 2021 Mar 4. Epub 2021 Mar 4.

From the Department of Plastic Surgery Department of Dermatology, Kanto Central Hospital of the Mutual Aid Association of Public School Teachers, Kamiyoga, Setagaya-ku, Tokyo Japan.

Abstract: Morbihan disease is a rare condition characterized by persistent erythema and solid edema of the upper two thirds of the face, leading to visual impairment and significant esthetic disfigurement. The underlying etiology of the disease remains uncertain, but its correlation with lymphoedema has been conjectured. Definitive treatment options are also lacking, and most current topical, systemic, and surgical interventions provide transient or partial results. Read More

Drug Des Devel Ther 2021 22;15:743-752. Epub 2021 Feb 22.

Department of Hematology and Oncology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing Key Laboratory of Pediatric Hematology Oncology, Key Laboratory of Major Diseases in Children, Ministry of Education, National Key Discipline of Pediatrics, Beijing, People's Republic of China.

Objective: This study aimed to evaluate the effectiveness of Ruxolitinib for acute/chronic graft-versus-host disease in children.

Methods: This study was a retrospective trial. We analyzed the clinical characteristics of children who responded poorly to previous treatment for graft-versus-host disease (GVHD) and received ruxolitinib treatment after allogeneic hematopoietic stem cell transplantation (allo-HSCT) as an additional or replacement therapy. Read More

Arch Esp Urol 2021 Mar;74(2):254-260

Urology Department. University of Modena & Reggio Emilia. Modena. Italy.

Objective: To evaluate the safety and efficacy of prostatic artery embolization in the management of LUTS secondary to BPH in elderly patients unfit for surgery.

Materials And Methods: 17 elderly patients with moderate to severe LUTS/BPH were included in the study and treated with prostatic artery embolization. The patients were evaluated by transrectal ultrasonography (to assess prostate size), IPSS, and PVR urine volume preoperatively and 6 months after the procedure. Read More

Behav Brain Res 2021 May 26;405:113204. Epub 2021 Feb 26.

Laboratory of Neuroscience, Department of Psychology, University of Oviedo, Plaza Feijóo, s/n, E-33003, Oviedo, Spain; Instituto de Neurociencias del Principado de Asturias (INEUROPA), Oviedo, Spain. Electronic address:

Retaking routes after a period of time usually occurs in an environment which has suffered from spatial configuration modifications. Thus, the original visual stimuli that allowed us to establish cognitive mapping using an allocentric strategy during the acquisition phase may not remain physically identical at the time of retrieval. However, in the standard experimental paradigms the cues are typically maintained constant. Read More

Allergy 2021 Feb 28. Epub 2021 Feb 28.

Center for Basic and Clinical Immunology Research (CISI), WAO Center of Excellence, Department of Translational Medical Sciences, Allergy and Clinical Immunology, University of Naples Federico II, Naples, Italy.

Background: Orofacial granulomatosis (OFG) is characterized by granulomatous inflammation of the soft tissues of maxillofacial region. We explored OFG patients from 10different Italian Centers and summarized the most recent literature data.

Methods: a review ofpatients with OFG was carried out. Read More

Brain Res Bull 2021 May 22;170:234-245. Epub 2021 Feb 22.

Institute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, PR China. Electronic address:

Background: Intracerebral hemorrhage (ICH) is the top lethal and disabling form of stroke. The pathophysiology of ICH is not fully understood yet. Metabolites are indicators and regulators of cellular processes. Read More

Int J Low Extrem Wounds 2021 Feb 24:1534734620982238. Epub 2021 Feb 24.

Seoul National University, Seoul, Republic of Korea.

The anterolateral thigh flap is a classic flap used for various reconstruction defects. However, the flap viability of extended large skin paddles (ie, 240 cm) was doubted by many surgeons. This study reports successful experience of reconstructing extensive soft tissue defects of lower extremity using extended large skin paddles. Read More

Pan Afr Med J 2020 21;37:257. Epub 2020 Nov 21.

Division of Plastic Reconstructive and Aesthetic Surgery, Dr. Kariadi Central General Hospital, Semarang, Central Java, Indonesia.

Hypermetabolic conditions with nutrition deficiencies are common in patients with extensive burns. Balanced nutrition status is required to achieve adequate wound healing. Mental disorder, which tended to make a patient uncooperative, complicates the management. Read More

Gan To Kagaku Ryoho 2021 Feb;48(2):273-275

Dept. of Surgery, Kansai Rosai Hospital.

A 80s year old man was referred to our hospital with melena. Colonoscopy revealed an elevated lesion in the sigmoid colon. Laparoscopic sigmoidectomy(D2)was performed in August 2011. Read More