2,900 results match your criteria successful dissemination

Development of the Three Antimicrobial Stewardship E's (TASE) framework and Association between Stewardship Interventions and intended Results (ASIR) analysis to identify key facility-specific interventions and strategies for successful antimicrobial stewardship.

Clin Infect Dis 2021 May 13. Epub 2021 May 13.

Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.

Background: Successful antimicrobial stewardship (AS) interventions have been described previously. Currently, a uniform operational approach to planning and implementing successful AS interventions does not exist. From 2015 to 2019, concomitant vancomycin and piperacillin-tazobactam use (CVPTU) for >48 hours at Vanderbilt University Medical Center (VUMC) significantly decreased through AS efforts. Read More

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Health literacy in people with venous leg ulcers: a protocol for scoping review.

BMJ Open 2021 May 11;11(5):e044604. Epub 2021 May 11.

School of Psychology, University of Birmingham Edgbaston Campus, Birmingham, UK.

Introduction: Chronic venous leg ulcer (VLU) healing is a complex clinical problem. It requires intervention from skilled, costly, multidisciplinary wound-care teams, working with patients to manage their care. Compression therapy has been shown to help heal venous ulcers and to reduce recurrence, with some evidence suggesting the value of exercise as well. Read More

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Novel chromosomal insertions of ISEcp1-bla and diverse antimicrobial resistance genes in Zambian clinical isolates of Enterobacter cloacae and Escherichia coli.

Antimicrob Resist Infect Control 2021 May 10;10(1):79. Epub 2021 May 10.

Division of Infection and Immunity, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Japan.

Background: The epidemiology of extended-spectrum β-lactamases (ESBLs) has undergone dramatic changes, with CTX-M-type enzymes prevailing over other types. bla genes, encoding CTX-M-type ESBLs, are usually found on plasmids, but chromosomal location is becoming common. Given that bla-harboring strains often exhibit multidrug resistance (MDR), it is important to investigate the association between chromosomally integrated bla and the presence of additional antimicrobial resistance (AMR) genes, and to identify other relevant genetic elements. Read More

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Dissemination of Evidence-Based Practice Projects: Key Strategies for Successful Poster Presentations.

Worldviews Evid Based Nurs 2021 May 9. Epub 2021 May 9.

College of Nursing, The Ohio State University, Columbus, OH, USA.

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Catalogue of Communication Tools and Dissemination Guidelines: benchmarking current practice in EU and Member State bodies.

EFSA J 2021 Apr 29;19(4):e190402. Epub 2021 Apr 29.

A comprehensive benchmarking exercise on current best practices on communication tools and dissemination processes of EU Member State organisations plus Iceland and Norway, selected ENVI EU agencies (EFSA, EMA, ECHA, ECDC), and EU bodies (DG SANTE, JRC, EU COUN) was carried out via an online survey, remote qualitative interviews, and a desk analysis of documents and web content.These current practices have been compiled into a catalogue of communication tools and a guide to their effective dissemination. Both elements are designed to help inform the EC General Plan for Risk Communication (GPRC)andfacilitate a coordinated communication framework at the EU and national level on matters relating to the food chain. Read More

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Evaluation of health care providers' use of the 'Exercise and Depression Toolkit': a case study.

BMC Psychiatry 2021 May 8;21(1):243. Epub 2021 May 8.

Department of Kinesiology, Faculty of Education, University of British Columbia, 210-6081 University Boulevard, Vancouver, BC, V6T 1Z1, Canada.

Background: Exercise is now recommended as a primary treatment for mild-moderate depression in Canada. The 'Exercise and Depression Toolkit' was developed to help health care providers (HCP) integrate these treatment guidelines into practice. The purpose of this study was to evaluate acceptability and perceived effectiveness of the toolkit in practice by HCPs working with individuals with depression. Read More

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Achieving oncology mental health providers' usage of an empirically supported treatment: Lessons learned.

Psychooncology 2021 May;30(5):794-803

Department of Oncology, Georgetown University Medical Center, Washington, DC, USA.

Objective: There is a need for oncology mental health providers to receive training to use empirically supported psychological treatments (ESTs) with their patients. The purpose of this editorial is to describe "lessons learned" from disseminating-conducting EST trainings-and supporting providers' capacity and confidence to use the EST.

Method: Processes and outcomes from conducting six, 3-days (18 h) EST training institutes from 2012-2016 are discussed. Read More

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Digital Clinics and Mobile Technology Implementation for Mental Health Care.

Curr Psychiatry Rep 2021 05 7;23(7):38. Epub 2021 May 7.

Division of Digital Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02446, USA.

Purpose Of Review: Interest in digital mental health, especially smartphone apps, has expanded in light of limited access to mental health services and the need for remote care during COVID-19. Digital clinics, in which apps are blended into routine care, offer a potential solution to common implementation challenges including low user engagement and lack of clinical integration of apps.

Recent Findings: While the number of mental health apps available in commercial marketplaces continues to rise, there are few examples of successful implementation of these apps into care settings. Read More

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Follow-Up of Coronavirus Infected Patients Using Telemedicine in a Referral Pulmonary Center.

Tanaffos 2020 Dec;19(4):356-363

Telemedicine research center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti university of Medical Sciences, Tehran, Iran.

Background: Telemedicine is considered an innovative approach for management and follow up of communicable diseases, when person to person contact has the risk of disease dissemination, such as the situation being experienced with corona virus infection. The aim of this study was to evaluate the role of telemedicine in patient follow-up and patient compliance in different communication methods.

Materials And Methods: All patients discharged from a referral pulmonary hospital dedicated to coronavirus infected patients were given instructions on follow-up of symptoms. Read More

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December 2020

Factors predicting successful vaginal birth after caesarean section: protocol for evidence-based consensus recommendations using a Delphi survey.

BMJ Open 2021 May 5;11(5):e047433. Epub 2021 May 5.

Department of Anorectal Surgery, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China

Introduction: With the wide adoption of the two-child policy in China since 2016, a large percentage of women with a history of caesarean delivery plan to have a second child. Accordingly, the rate of vaginal birth after caesarean (VBAC) delivery is increasing. Women attempting repeat VBAC may experience multiple morbidities, which is also one of the leading causes of maternal and perinatal mortality. Read More

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Prospective cohort study comparing a triceps-sparing and triceps-detaching approach in total elbow arthroplasty: a protocol.

BMJ Open 2021 May 5;11(5):e046098. Epub 2021 May 5.

Department of Orthopedic Surgery, University Medical Center Groningen, Groningen, The Netherlands.

Background: New surgical approaches have been developed to optimise elbow function after total elbow arthroplasty (TEA). Currently, there is no consensus on the best surgical approach. This study aims to investigate the functional outcomes, prosthetic component position and complication rates after a triceps-sparing and a triceps-detaching approach in TEA. Read More

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Evaluation of an integrated treatment to address smoking cessation and anxiety/depressive symptoms among people living with HIV: Study protocol for a randomized controlled trial.

Contemp Clin Trials 2021 Apr 30;106:106420. Epub 2021 Apr 30.

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America; Department of Psychiatry, Harvard Medical School, Boston, MA, United States of America; The Fenway Institute, Fenway Health, Boston, MA, United States of America. Electronic address:

Background: Interventions that target anxiety/depressive symptoms in the context of smoking treatment have shown promise irrespective of psychiatric diagnosis. Yet, these tailored treatments are largely absent for persons who smoke and are living with HIV (SLWH).

Objective: To evaluate a novel, smoking cessation intervention that addresses anxiety/depression and HIV-related health (QUIT) against a time-matched control (TMC) and a standard of care (SOC) condition. Read More

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Factors associated with successful implementation of telehealth abortion in 4 United States clinical practice settings.

Contraception 2021 Apr 29. Epub 2021 Apr 29.

Department of Family Medicine, University of Washington, Washington, WA, United States.

Objective: To overcome obstacles to delivering medication abortion services during the COVID-19 pandemic, clinics and providers implemented new medication abortion service models not requiring in-person care. This study identifies organizational factors that promoted successful implementation of telehealth and adoption of "no test" medication abortion protocols.

Study Design: We conducted 21 semi-structured, in-depth interviews with health care providers and clinic administrators implementing clinician-supported telehealth abortion during the COVID pandemic. Read More

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Dissemination Science in School Mental Health: A Framework for Future Research.

School Ment Health 2021 Apr 18:1-17. Epub 2021 Apr 18.

Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, 6200 NE 74th St, Suite 100, Seattle, WA 98115 USA.

There has been an increase in school mental health research aimed at producing generalizable knowledge to address longstanding science-to-practice gaps to increase children's access to evidence-based mental health services. Successful dissemination and implementation are both important pieces to address science-to-practice gaps, but there is conceptual and semantic imprecision that creates confusion regarding where dissemination ends and implementation begins, as well as an imbalanced focus in research on implementation relative to dissemination. In this paper, we provide an enhanced operational definition of dissemination; offer a conceptual model that outlines elements of effective dissemination that can produce changes in awareness, knowledge, perceptions, and motivation across different stakeholder groups; and delineate guiding principles that can inform dissemination science and practice. Read More

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Surrogate broodstock to enhance biotechnology research and applications in aquaculture.

Biotechnol Adv 2021 Apr 22;49:107756. Epub 2021 Apr 22.

The Roslin Institute, University of Edinburgh, Easter Bush Campus, Roslin EH25 9RG, UK. Electronic address:

Aquaculture is playing an increasingly important role in meeting global demands for seafood, particularly in low and middle income countries. Genetic improvement of aquaculture species has major untapped potential to help achieve this, with selective breeding and genome editing offering exciting avenues to expedite this process. However, limitations to these breeding and editing approaches include long generation intervals of many fish species, alongside both technical and regulatory barriers to the application of genome editing in commercial production. Read More

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Approaches for discontinuation versus continuation of long-term antidepressant use for depressive and anxiety disorders in adults.

Cochrane Database Syst Rev 2021 04 15;4:CD013495. Epub 2021 Apr 15.

Clinical Pharmacology Unit, Department of Basic and Applied Medical Sciences, Ghent University, Ghent, Belgium.

Background: Depression and anxiety are the most frequent indication for which antidepressants are prescribed. Long-term antidepressant use is driving much of the internationally observed rise in antidepressant consumption. Surveys of antidepressant users suggest that 30% to 50% of long-term antidepressant prescriptions had no evidence-based indication. Read More

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Broadening the impact of plant science through innovative, integrative, and inclusive outreach.

Plant Direct 2021 Apr 14;5(4):e00316. Epub 2021 Apr 14.

Department of Biology Stanford University Stanford CA USA.

Population growth and climate change will impact food security and potentially exacerbate the environmental toll that agriculture has taken on our planet. These existential concerns demand that a passionate, interdisciplinary, and diverse community of plant science professionals is trained during the 21st century. Furthermore, societal trends that question the importance of science and expert knowledge highlight the need to better communicate the value of rigorous fundamental scientific exploration. Read More

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Genomic Diversity and Virulence Potential of ESBL- and AmpC-β-Lactamase-Producing Strains From Healthy Food Animals Across Europe.

Front Microbiol 2021 1;12:626774. Epub 2021 Apr 1.

NG1 Microbial Genomics, Robert Koch Institute, Berlin, Germany.

The role of livestock animals as a putative source of ESBL/pAmpC for humans is a central issue of research. In a large-scale pan-European surveillance, 2,993 commensal spp. isolates were recovered from randomly collected fecal samples of healthy cattle, pigs and chickens in various abattoirs. Read More

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Protocol for a mixed-method study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate breast reconstruction in women unsuitable for standard breast-conserving surgery (the ANTHEM Feasibility Study).

BMJ Open 2021 Apr 16;11(4):e046622. Epub 2021 Apr 16.

Bristol Centre for Surgical Research, Population Health Sciences, Bristol Medical School, Bristol, UK.

Introduction: Approximately 40% of the 55 000 women diagnosed with breast cancer each year in the UK undergo mastectomy because they are considered unsuitable for standard breast-conserving surgery (BCS) due to tumour size or multiple tumour foci. Mastectomy can significantly impact women's quality of life, and only one in four women currently undergo immediate breast reconstruction (IBR).Level 2 oncoplastic breast-conserving surgery (OPBCS) combines removing the cancer with a range of plastic surgical volume replacement (eg, local perforator flaps) and volume displacement techniques (eg, therapeutic mammaplasty) that can extend the role of BCS and may allow some women not suitable for standard BCS to avoid mastectomy. Read More

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Molecular Characterisation of Plasmids Encoding bla from Faecal Escherichia coli in Travellers Returning to the UK from South Asia.

J Hosp Infect 2021 Apr 13. Epub 2021 Apr 13.

Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham, UK, B15 2TT; Public Health England Laboratory, University Hospitals Birmingham, Heartlands Hospital, Bordesley Green East, Birmingham, UK, B9 5SS; Department of Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill Road, Aberdeen, AB25 2ZN.

Background: The global prevalence of ESBL-producing Escherichia coli is rising and is dominated by bla spread by plasmids. Travellers to South Asia from Western Europe have high rates of acquisition of faecal CTX-M-producing E. coli (CTX-M-EC). Read More

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A review of implementation frameworks to operationalize health technology assessment recommendations for medical technologies in the Singapore setting.

Int J Technol Assess Health Care 2021 Apr 12;37(1):e56. Epub 2021 Apr 12.

Agency for Care Effectiveness (ACE), Ministry of Health Singapore, 16 College Road, Singapore169854, Singapore.

Background: Methodologies of health technology assessment (HTA) for medical technologies are well established; yet, operational frameworks that enable appropriate uptake of HTA recommendations into routine clinical practice are lacking. This review aims to identify the key themes needed to guide the planning and implementation of HTA subsidy decisions for medical technologies such as diagnostics, medical devices, and services and to monitor their impact on a complex multipayer healthcare system like Singapore.

Methods: A literature search of implementation frameworks was conducted up to 20 December 2020 and was documented in a flow diagram. Read More

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Understanding the impact of a residential housing programme for people living with HIV/AIDS: a realist evaluation protocol.

BMJ Open 2021 Apr 5;11(4):e044522. Epub 2021 Apr 5.

Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Introduction: Housing instability and homelessness are significant barriers to medical treatment for people living with HIV/AIDS. For these individuals, lack of stable housing and stigma is associated with insufficient access to care, poor adherence to medication and higher cost burdens to the healthcare system. This protocol reports on the efforts to evaluate Sanctum V. Read More

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COVID-19 vaccine challenges: What have we learned so far and what remains to be done?

Health Policy 2021 05 26;125(5):553-567. Epub 2021 Mar 26.

London School of Economics & Political Science, United Kingdom; Imperial College London, United Kingdom. Electronic address:

Developing and distributing a safe and effective SARS-CoV-2 (COVID-19) vaccine has garnered immense global interest. Less than a year after COVID-19 was declared a pandemic, several vaccine candidates had received emergency use authorization across a range of countries. Despite this scientific breakthrough, the journey from vaccine discovery to global herd immunity against COVID-19 continues to present significant policy challenges that require a collaborative, global response. Read More

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Syringe service program-based telemedicine linkage to opioid use disorder treatment: protocol for the STAMINA randomized control trial.

BMC Public Health 2021 03 31;21(1):630. Epub 2021 Mar 31.

Departments of Academic Internal Medicine and Pediatrics, University of Illinois Chicago, 840 S Wood St, Chicago, IL, 60612, USA.

Background: A key strategy for mitigating the current opioid epidemic is expanded access to medications for treating opioid use disorder (MOUD). However, interventions developed to expand MOUD access have limited ability to engage opioid users at higher levels of overdose risk, such as those who inject opioids. This paper describes the study protocol for testing STAMINA (Syringe Service Telemedicine Access for Medication-assisted Intervention through NAvigation), an intervention that engages high-risk opioid users at community-based syringe service programs (SSP) and quickly links them to MOUD using a telemedicine platform. Read More

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Recruiting general practitioners and patients with dementia into a cluster randomised controlled trial: strategies, barriers and facilitators.

BMC Med Res Methodol 2021 Mar 30;21(1):61. Epub 2021 Mar 30.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Medical Sociology and Rehabilitation Science, Charitéplatz 1, 10117, Berlin, Germany.

Background: Recruitment of general practitioners (GPs) and their patients is reported as one of the most challenging steps when undertaking primary care research. The present paper describes the recruitment process of a cluster randomised controlled trial (cRCT) aiming to improve dementia care in the primary care setting.

Methods: Recruitment data was analysed descriptively using frequency tables to investigate comparisons of recruitment rates and results of different recruitment strategies as well as reasons for participation and non-participation of GPs, patients with dementia (PwD) and their caregivers. Read More

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Implementation of nurse navigation for behavioral health inpatient services to divert early readmissions: A pilot program.

Rosemary Nourse

Arch Psychiatr Nurs 2021 Apr 27;35(2):168-171. Epub 2021 Jan 27.

Behavioral Health Nurse Navigator for Inpatient Services, St. Luke's University Health Network, Sacred Heart Campus, 421 Chew Street, Allentown, PA 18102, United States of America. Electronic address:

Objective: Inpatient behavioral health units across the United States have high readmission rates. The Centers for Medicare and Medicaid Services (CMS) as well as healthcare organizations are focused on reducing readmission rates, especially those readmissions that occur within 30-90 days. Behavioral Health Nurse Navigation was implemented at St. Read More

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TEVAR for thoracic mycotic aneurysm: Case report.

Int J Surg Case Rep 2021 Apr 13;81:105753. Epub 2021 Mar 13.

Vascular surgery department, Ibn Sina University Hospital center, Université Mohammed V, faculté de médecine et de pharmacie de Rabat, 10104, Souissi, Rabat, Morocco.

Introduction: Mycobacterium tuberculosis is a cause of mycotic aortic pseudoaneurysms, wich are a rare case with high mortality rates. Three types of dissemination hematogenous by contiguity and direct to the aortic wall are possibles.

Presentation Of Case: We report a rare case of tuberculous thoracic aortic pseudo aneurysm, successfully treated endovascularly associated to antituberculosis drugs. Read More

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Building a successful international research community through data sharing: The case of the Wheat Information System (WheatIS).

F1000Res 2020 5;9:536. Epub 2020 Jun 5.

Université Paris-Saclay, INRAE, URGI, Versailles, 78026, France.

The International Wheat Information System (WheatIS) Expert Working Group (EWG) was initiated in 2012 under the Wheat Initiative with a broad range of contributing organizations. The mission of the WheatIS EWG was to create an informational infrastructure, establish data standards, and build a single portal that allows search, retrieval, and display of globally distributed wheat data sets that are indexed in standard data formats at servers around the world. The web portal at WheatIS. Read More

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Nondestructive detection of photonic qubits.

Nature 2021 Mar 24;591(7851):570-574. Epub 2021 Mar 24.

Max-Planck-Institut für Quantenoptik, Garching, Germany.

One of the biggest challenges in experimental quantum information is to sustain the fragile superposition state of a qubit. Long lifetimes can be achieved for material qubit carriers as memories, at least in principle, but not for propagating photons that are rapidly lost by absorption, diffraction or scattering. The loss problem can be mitigated with a nondestructive photonic qubit detector that heralds the photon without destroying the encoded qubit. Read More

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Protocol for a systematic review of barriers, facilitators and outcomes in primary healthcare services for women in Pakistan.

BMJ Open 2021 Mar 24;11(3):e043715. Epub 2021 Mar 24.

Department of Social Policy and Intervention, University of Oxford, Oxford, UK.

Introduction: The lack of universal health coverage and high poverty rates among the majority of women in Pakistan makes it essential to understand the quality and effectiveness of primary healthcare services. The aim of this project is to systematically review the available literature for interventions for primary healthcare services for women in order to provide the basis for future healthcare policy. The primary objective is to identify the effectiveness of the intervention in terms of how successful it was in improving health of women; whereas the secondary aim is to identify barriers and facilitators for delivery of primary healthcare services. Read More

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