1,085 results match your criteria substernal goiter

Risk Factors and Outcomes of Postoperative Neck Hematomas: An Analysis of 5,900 Thyroidectomies Performed at a Cancer Center.

Int Arch Otorhinolaryngol 2021 Jul 30;25(3):e421-e427. Epub 2020 Sep 30.

AC Camargo Cancer Center, São Paulo, SP, Brazil.

 Postoperative neck hematoma (PNH) is an uncommon but potentially-lethal complication of thyroid surgery.  To identify the risk factors for postthyroidectomy hematoma requiring reoperation, the timing, the source of the bleeding, the related respiratory distress requiring tracheotomy, and the late outcomes.  We retrospectively analyzed the records of 5,900 consecutive patients submitted to surgery for thyroid diseases at a single institution. Read More

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Sutureless Thyroidectomy With Intraoperative Neuromonitoring and Energy-Based Device Without Sternotomy for Symptomatic Substernal Goiter Harboring Thyroiditis of Gland Parenchyma.

Cureus 2021 Jul 8;13(7):e16258. Epub 2021 Jul 8.

General Surgery, Giresun University Faculty of Medicine, Giresun, TUR.

Since substernal goiter first being described by Haller in 1749, a consensus on the definition of this entity has not been ensured, yet. Despite substernal goiter or retrosternal goiter is delineated as an enlarged thyroid gland with a component extending into the mediastinum, at least 10 definitions have described being able to depict the most accurate definition for substernal goiter. Of note, no consensus still has been declared on the therapeutic management of asymptomatic substernal goiter. Read More

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Estimation of Chest Wall Attenuation of I Emissions in Substernal Goiter: A Phantom Study.

J Nucl Med Technol 2021 Sep 9;49(3):232-234. Epub 2021 Jul 9.

Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

In patients with substernal goiter, the generally accepted theory is that thyroid uptake measurements with iodine isotopes are underestimated because of attenuation by the chest wall. The extent of this underestimation is not well known. In this study, we calculated the attenuation of I emissions using a cadaver chest wall with a thyroid probe to better understand the potential severity of this underestimation. Read More

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September 2021

Efficacy and safety of single-session radiofrequency ablation for intrathoracic goiter: preliminary results and short-term evaluation.

Int J Hyperthermia 2021 ;38(1):976-984

Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background: An intrathoracic goiter (ITG) is defined as a thyroid extension below the sternal notch. Compared to cervical goiters, surgery for ITG is more challenging, with a higher risk of an extracervical approach. Ultrasound (US)-guided radiofrequency ablation (RFA) is a minimally invasive treatment modality. Read More

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Airway Management in Substernal Goiter Surgery.

Ann Otol Rhinol Laryngol 2021 May 25:34894211014794. Epub 2021 May 25.

Department of Otolaryngology-Head & Neck Surgery, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.

Objective(s): To review the experience of 3 hospitals with airway management during surgery for substernal goiter and identify preoperative factors that predict the need for advanced airway management techniques.

Methods: A retrospective chart review between 2009 and 2017 of patients with substernal goiter treated surgically at 1 of 3 hospitals was performed.

Results: Of the 179 patients included in the study, 114 (63. Read More

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Anatomical and developmental aspects of iatrogenic injury to the right recurrent laryngeal nerve in surgical resections of substernal goiter.

Anat Rec (Hoboken) 2021 06 9;304(6):1242-1254. Epub 2021 Apr 9.

Hospital Universitario Gaffree e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.

Thyroid surgery is the primary treatment for substernal goiters, and iatrogenic injury to the recurrent laryngeal nerve (RNL) is always a risk. The literature suggests that iatrogenic lesions of the RNL post resection of substernal goiter are not equally distributed, being more frequent on the right recurrent laryngeal nerve (R-RLN) in comparison to the left recurrent laryngeal nerve (L-RLN). The relative paucity of basic anatomical and clinical reportages on R-RLN iatrogenic injuries and on the developmental factors that may help explain its higher incidence justifies this study's undertaking. Read More

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Cardiopulmonary Arrest Caused by Large Substernal Goiter-Treatment with Combined Cervical Approach and Median Mini-Sternotomy: Report of a Case.

Medicina (Kaunas) 2021 Mar 24;57(4). Epub 2021 Mar 24.

3rd Surgery Department, Medical School of Health Sciences, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.

Introduction: Substernal goiter is usually defined as a goiter that extends below the thoracic inlet or a goiter with more than 50% of its mass lying below the thoracic inlet. Substernal goiters may compress adjacent anatomical structures causing a variety of symptoms.

Case Report: Here we report a rare case of a 75-year-old woman presenting with cardiac arrest caused by acute respiratory failure due to tracheal compression by a substernal goiter. Read More

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Combined cervicosternotomy and cervicotomy for true retrosternal goiters: a surgical cohort study.

Updates Surg 2021 Aug 29;73(4):1-10. Epub 2021 Mar 29.

Department of Head and Skin, University Hospital Ghent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.

Objective: Intrathoracic goiters are a heterogeneous group characterized by limited or extensive substernal extension. Whereas the former can be treated through cervicotomy, the latter sometimes requires a cervicosternotomy. Whether cervicosternotomy leads to more morbidity remains unclear. Read More

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Cervical approach to cervico-mediastinal goiters: Experience of a Moroccan ENT tertiary center - Case series.

Ann Med Surg (Lond) 2021 Feb 26;62:353-357. Epub 2021 Jan 26.

ENT Head and Neck Surgery Department, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Background: The purpose of the study was to analyze and discuss the demographic, clinical, radiological, therapeutic and postoperative findings of the Cervico-mediastinal goiters (CMG) treated through a cervical approach admitted in the ENT department of Ibn Rochd university hospital, Casablanca, Morocco between January 2014 and January 2020.

Materiels And Methods: Over a period of 6 years, 116 patients underwent surgical treatment for CMG. It was defined as a goiter extending below the plane of superior thoracic aperture on CT scan. Read More

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February 2021

Sutureless Total Thyroidectomy for Substernal Goiter: Amending Versus Unnecessary.

Cureus 2021 Jan 15;13(1):e12720. Epub 2021 Jan 15.

Pathology, Giresun University Faculty of Medicine, Giresun, TUR.

Substernal goiter is an enlarged thyroid gland, harboring a component extending into the mediastinum. Surgical management requires genuine and rigorous preoperative planning as physicians could encounter the prospect of the gland coming into close quarters with the vital intrathoracic structures. The neck and chest multiplanar cross-sectional imaging provide essentialness of an extracervical approach for the procedure. Read More

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January 2021

Retrosternal goiter.

Rozhl Chir 2020 ;99(11):492-496

Introduction: Retrosternal goiter is an enlarged thyroid mass of which more than 50% is located in the mediastinum. Indications for surgery of retrosternal goiter include ineffective pharmacological treatment, mechanical syndrome, suspicion of malignancy and thyrotoxicosis. Computed tomography is the gold standard in the diagnosis of retrosternal goiter. Read More

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January 2021

fT3:fT4 ratio in Graves' disease - correlation with TRAb level, goiter size and age of onset.

Folia Med Cracov 2020 09;60(2):15-27

Department of Endocrinology Jagiellonian University Medical College.

Introduction: Graves' Disease (GD) is an autoimmune hyperthyroidism occurring mostly in young women. The main pathogenic role of the disease is attributed to TSH receptor antibodies (TRAb), which stimulate the thyroid gland to increase production of the most active thyroid hormone- triiodothyronine (T3). High level of TRAb and a large goiter size are commonly known as poor prognostic factors for the disease and are used to predict relapse. Read More

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September 2020

To explore the risk factors and preventive measures affecting the treatment of retrosternal goiter: An observational study.

Medicine (Baltimore) 2020 Oct;99(44):e23003

Department of Head and Neck, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, P.R. China.

The definition of substernal goiter (SG) is based on variable criteria, leading to considerable variations in the reported incidence (from 0.2% to 45%). The peri- and postoperative complications are higher in total thyroidectomy (TT) for SG than that for cervical goiter. Read More

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October 2020

Enlargement of Intrathoracic Goiter with Unilateral Phrenic Nerve Paralysis Leading to Cardiopulmonary Arrest.

Intern Med 2021 Jan 5;60(1):91-97. Epub 2020 Sep 5.

Department of Respiratory Surgery, National Hospital Organization Hokkaido Medical Center, Japan.

As an intrathoracic goiter expands, it causes airway stenosis and phrenic nerve paralysis, and slight respiratory stimuli can trigger sudden life-threatening hypoventilation. A 78-year-old obese woman with a large intrathoracic goiter was found unconscious with agonal breathing in her room early in the morning. Cardiopulmonary resuscitation restored spontaneous circulation. Read More

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January 2021

An overview of retrosternal goiter.

M Knobel

J Endocrinol Invest 2021 Apr 11;44(4):679-691. Epub 2020 Aug 11.

Thyroid Unit, Division of Endocrinology and Metabolism, Hospital das Clínicas, School of Medicine, Universidade de São Paulo, Av. Dr. Eneas de Carvalho Aguiar, 155, 8th floor, bl 3, PAMb, São Paulo, 05403-900, Brazil.

Goiters tend to grow slowly and steadily over many years, occasionally reaching the mediastinum and extending through the thoracic inlet into the visceral compartment. In most cases, retrosternal goiters originate from the cervical portion of the thyroid. The incidence of retrosternal goiters varies considerably, ranging from 0. Read More

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Peculiar anatomic variation of recurrent laryngeal nerve and EMG change in a patient with right substernal goiter and pre-operative vocal cord palsy-case report.

Gland Surg 2020 Jun;9(3):802-805

School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.

We report a patient with right substernal goiter and preoperative vocal cord palsy (VCP). During dissection, an anatomic variation of the recurrent laryngeal nerve (RLN) and a prolonged EMG were detected by intraoperative neuromonitoring (IONM). Symmetrical vocal cord movement was recorded one month after surgery. Read More

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Substernal goiter excision in a Jehovah's Witness.

Proc (Bayl Univ Med Cent) 2020 Jul 30;33(3):462-464. Epub 2020 Mar 30.

Division of Maxillofacial Oncology and Reconstructive Surgery, Department of Oral and Maxillofacial Surgery, John Peter Smith Health NetworkFort WorthTexas.

Jehovah's Witnesses present a unique challenge in oral and head and neck surgery. We report a case of a substernal goiter excised on a Jehovah's Witness without the use of blood transfusion, in accordance with the patient's beliefs. Additionally, we review the literature on the care of this patient population, focusing on preoperative optimization, perioperative management, and postoperative care. Read More

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Substernal Goiter: a case to remember.

Rev Assoc Med Bras (1992) 2020 May;66(2):109-111

. Department of Internal Medicine. Hospital Trofa Saúde Vila Real. Vila Real, Portugal.

Goiter is a localized or generalized thyroid hypertrophy. It can remain within the cervical region or grow down until it invades the mediastinum. The signs and symptoms depend on the size and location of the goiter. Read More

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Surgery for retrosternal goiter: cervical approach.

Gland Surg 2020 Apr;9(2):392-400

Department of Head and Neck Surgery, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China.

Background: Retrosternal goiter refers to when the thyroid gland extends from the neck to the substernal portion, descending below the thoracic inlet into the mediastinum. It is typically accompanied by compressive symptoms, and most patients need to undergo surgery. This retrospective study set out to analyze the surgical approach to retrosternal goiter and to evaluate perioperative complications, with the aim of recommending best surgical technique. Read More

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Giant Intrathoracic Goiter of Atypical Presentation: A Case Report.

Clin Pathol 2020 Jan-Dec;13:2632010X20916741. Epub 2020 Apr 23.

Faculty of Health Sciences, Universidad Icesi, Cali, Colombia.

Background: The term goiter is used to describe any abnormal growth of the thyroid gland, which can be diffuse or nodular, and can be associated with normal, diminished, or increased thyroid function. Multinodular goiter is a common disease whose prevalence increases at age 50. Clinical manifestations can be due to thyroid function impairment or related to size and location of the gland with compressive symptoms. Read More

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Averting Risk of Airway Loss During Surgical Management of Retrosternal Goiters.

J Cardiothorac Vasc Anesth 2020 Aug 19;34(8):2260-2268. Epub 2020 Mar 19.

Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL. Electronic address:

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Thyroid Embryonic Anomalies Involving the Medial and Lateral Anlagen: Two Surgical Case Reports.

Case Rep Surg 2019 5;2019:3174848. Epub 2019 Dec 5.

Department of Surgery, Texas Tech University Health Sciences Center, 1400 S Coulter, Amarillo, TX, USA 79106.

Introduction: An ectopic anomalous accessory thyroid is extremely rare. We present two related case reports.

Case: A 43-year-old morbidly obese female presented with a palpable left thyroid mass. Read More

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December 2019

A not-so-incidental retrosternal goitre.

Br J Hosp Med (Lond) 2019 Dec;80(12):736

Consultant Physician in General Internal Medicine, Department of Medicine, Mayo University Hospital, Castlebar, Co. Mayo, Ireland.

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December 2019

Extracorporeal membrane oxygenation for the anesthetic management of a patient with a massive intrathoracic goiter causing severe tracheal obstruction with positional symptoms: A case report.

Medicine (Baltimore) 2019 Oct;98(42):e17650

Department of Anesthesiology and Pain Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Introduction: Perioperative anesthetic management in cases of severe airway obstruction with positional symptoms can be associated with difficulties in ventilation or intubation, with a risk of acute respiratory decompensation at every stage of anesthesia.

Patient Concerns: Here we describe the anesthetic management of a 67-year-old man with a massive intrathoracic goiter causing severe tracheal obstruction with positional symptoms. The patient presented with progressive dyspnea that was aggravated in the supine position and was scheduled for total thyroidectomy. Read More

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October 2019

Intrapericardial goiter.

Gen Thorac Cardiovasc Surg 2020 Sep 3;68(9):1051-1054. Epub 2019 Oct 3.

Thoracic Surgery Department, Faculty İbn-I Sina Hospital, Ankara University School of Medicine, 06100, Sıhhiye, Ankara, Turkey.

Intrapericardial goiter cases are only a few in the literature. We present a 53-year-old woman who was operated for 8-cm anterior mediastinal mass located completely intrapericardial and histopathological examination revealed an ectopic goiter. It may be difficult to distinguish between mediastinal masses within or outside the pericardium. Read More

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September 2020

[Een rood en gezwollen gelaat na heffen van de armen].

Ned Tijdschr Geneeskd 2019 09 5;163. Epub 2019 Sep 5.

Noordwest Ziekenhuisgroep, afd. Interne Geneeskunde, Alkmaar.

An 82-year-old woman attended our outpatient clinic because of a swollen right arm and hoarseness. Upon raising both arms, the patient developed a red and swollen face (Pemberton's sign). An MRI of the thorax showed a large intrathoracic goitre, which compressed venous structures and limited blood flow even when she lowered her arms. Read More

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September 2019

Surgical approach to the substernal goiter.

Best Pract Res Clin Endocrinol Metab 2019 08 22;33(4):101312. Epub 2019 Aug 22.

Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, C-1064, New York, NY 10021, USA. Electronic address:

Surgery for substernal goiters can be technically demanding. Extensive mediastinal extension brings the thyroid gland into close quarters with vital intrathoracic structures. Proper preoperative planning is required to determine the potential need for an extracervical approach. Read More

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