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A template for physical resilience research in older adults: Methods of the PRIME-KNEE study.

J Am Geriatr Soc 2021 Jul 29. Epub 2021 Jul 29.

Duke University School of Medicine, Durham, North Carolina, USA.

Background: Older adults with similar health conditions often experience widely divergent outcomes following health stressors. Variable recovery after a health stressor may be due in part to differences in biological mechanisms at the molecular, cellular, or system level, that are elicited in response to stressors. We describe the PRIME-KNEE study as an example of ongoing research to validate provocative clinical tests and biomarkers that predict resilience to specific health stressors. Read More

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Women's views and experiences of maternity care during COVID-19 in Ireland: A qualitative descriptive study.

Midwifery 2021 Jul 14;103:103092. Epub 2021 Jul 14.

School of Nursing and Midwifery, University of Dublin Trinity College, 24 D'Olier Street, Dublin, Ireland.

Objective: To gain insight and understanding of women's views and experiences of maternity care during the COVID-19 pandemic in Ireland.

Design: A qualitative descriptive study using semi-structured interviews. Due to social distancing and associated COVID-19 restrictions at the time of the study, the interviews were held remotely via telephone. Read More

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"Does that mean I can't use my phone to pay when I'm in the Maccas drive thru?": Younger drivers' uncertainty and attitude toward smartphone law and punishment.

Accid Anal Prev 2021 Jul 26;160:106314. Epub 2021 Jul 26.

Monash University Accident Research Centre, Monash University, Australia.

This study employed a mixed methods approach (a survey [n = 2,774] and focus groups [n = 16]) to understand the perceptions of younger drivers (18-25) on current smartphone laws in the Australian state of Victoria. First, by analysing quantitative data gathered from an online survey regarding smartphone laws, perceptions of punishment when breaking the law, and attitudes to both the law and fines, this study found younger drivers were less likely to understand the law around phone use while driving, even after direct or indirect experience with police. Additionally, the severity and impact of fines were perceived as more impactful and severe among younger drivers, women, and those on lower incomes, and the most common types of illegal use younger drivers engaged with were navigation, music applications, and hands-free calling, mostly facilitated through Bluetooth with their device placed out of sight. Read More

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Increased non-attendance at epilepsy clinic in patients with neuropsychiatric comorbidities: A prospective study.

Epilepsy Behav 2021 Jul 26;122:108202. Epub 2021 Jul 26.

Epilepsy Clinic, National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Neurogenetics Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico. Electronic address:

Background: In patients with epilepsy, regular follow-up is vital for adequate seizure control, antiseizure drugs' (ASDs) side effects, psychiatric comorbidities, and planning for epilepsy surgery. Non-attendance creates barriers to adequate patient care, inefficient allocation of resources, loss of income, and unnecessary emergency department visits due to lack of seizure control. This study aimed to determine the causes and sociodemographic characteristics of the non-attendant population at the Epilepsy Clinic. Read More

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Prevalence of gout in the adult general population in Spain: estimating the proportion of undiagnosed cases.

Joint Bone Spine 2021 Jul 26:105257. Epub 2021 Jul 26.

Rheumatology, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.

Objective: To estimate the prevalence of gout in Spain.

Methods: Cross-sectional, population-based study of people aged 20 years or older. First, randomly selected individuals were contacted by telephone and rheumatic disease screening questionnaires were conducted. Read More

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Long-term Outcomes of High-Volume Stapled Hemorroidopexy to Treat Symptomatic Hemorrhoidal Disease.

Ann Coloproctol 2021 Jul 29. Epub 2021 Jul 29.

Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa, Italy.

Purpose: The study aimed to assess the long-term results of the stapled hemorrhoidopexy (SH) using high-volume devices equipped with innovative technology, evaluating recurrence rate, complications rate, and patients' satisfaction.

Methods: All the patients who underwent SH using high-volume devices (TST Starr plus, Touchstone International Medical Science Corp., Ltd. Read More

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"What Keeps Me Awake at Night": Assisted Living Administrator Responses to COVID-19.

Gerontologist 2021 Jul 29. Epub 2021 Jul 29.

Institute on Aging, Portland State University, Portland, OR, USA.

Background And Objectives: Assisted living (AL) constitutes an important sector of residential long-term care, yet there has been limited research about the impact of the coronavirus disease 2019 (COVID-19) pandemic in this setting. This qualitative study sought to understand the impact of the early stages of the pandemic (February-August 2020) from AL administrators' perspectives.

Research Design And Methods: Semi-structured phone interviews were conducted with 40 AL administrators in Oregon. Read More

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Experiences of people with opioid use disorder during the COVID-19 pandemic: A qualitative study.

PLoS One 2021 29;16(7):e0255396. Epub 2021 Jul 29.

Department of Emergency Medicine, St Paul's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.

Aim: To capture pandemic experiences of people with opioid use disorder (OUD) to better inform the programs that serve them.

Design: We designed, conducted, and analyzed semi-structured qualitative interviews using grounded theory. We conducted interviews until theme saturation was reached and we iteratively developed a codebook of emerging themes. Read More

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Older adults with non-communicable chronic conditions and their health care access amid COVID-19 pandemic in Bangladesh: Findings from a cross-sectional study.

PLoS One 2021 29;16(7):e0255534. Epub 2021 Jul 29.

Centre for Primary Health Care and Equity, University of New South Wales, Sydney, Australia.

Background: Burgeoning burden of non-communicable disease among older adults is one of the emerging public health problems. In the COVID-19 pandemic, health services in low- and middle-income countries, including Bangladesh, have been disrupted. This may have posed challenges for older adults with non-communicable chronic conditions in accessing essential health care services in the current pandemic. Read More

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Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.

Altern Ther Health Med 2021 Jul;27(4):8-13

Introduction: Knee pain, a common complaint in primary care, has many causes, the most common of which is osteoarthritis (OA). Other common causes are meniscus tears, tendinosis, ligament tears or sprains, rheumatoid arthritis, lupus and septic arthritis. Also, referred pain from hip joint pathology like slipped capital femoral epiphysis can result in knee pain. Read More

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Comparison of immunogenicity and reactogenicity of inactivated SARS-CoV-2 vaccine (CoronaVac) in previously SARS-CoV-2 infected and uninfected health care workers.

Hum Vaccin Immunother 2021 Jul 29:1-5. Epub 2021 Jul 29.

Memorial Ataşehir Hospital, Clinic of Pediatrics, İstanbul, Turkey.

The effects of inactivated SARS-CoV-2 vaccine (CoronaVac) on previously naturally infected individuals are unknown. This study compared immunogenicity and reactogenicity of CoronaVac in once naturally infected health-care workers (HCWs) and uninfected HCWs. All HCWs were immunized with two doses of CoronaVac (600 U/0. Read More

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Frontline nurses' experiences of working in a COVID-19 ward-A qualitative study.

Nurs Open 2021 Jul 29. Epub 2021 Jul 29.

Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.

Aim: To explore how nurses experienced working in a newly organized COVID-19 ward with high-risk patients during a new and unknown pandemic.

Design: A qualitative explorative study using a phenomenological-hermeneutic approach.

Methods: Semi-structured individual telephone interviews were conducted in June-July 2020 with 23 nurses working in COVID-19 wards from three regional hospitals in Denmark. Read More

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Implementing "chest pain pathway" using smartphone messaging application "WhatsApp" as a corrective action plan to improve ischemia time in "ST-Elevation myocardial Infarction" in primary PCI capable center "WhatsApp-STEMI Trial".

Wesam A AlHejily

Crit Pathw Cardiol 2021 Jul 27. Epub 2021 Jul 27.

Department of Medicine (Division of Cardiology) Faculty of Medicine, King Abdelaziz University Hospital, Jeddah, Saudi Arabia Department of Cardiology division at Dr Sulaiman Alhabib medical group.

Background: ST-elevation myocardial infarction (STEMI) is a life-threatening medical emergency that requires immediate medical attention, each hospital should implement a clinical pathway with a main objective to reduce ischemia time from diagnosis to revascularization, as this has shown to save myocardial tissues and subsequently patients' lives, utilizing the most evidence-based approach and the most up to date management protocol. In this study we aimed to assess the utility of structuring chest pain pathway with instantaneous case by case feedback protocol using WhatsApp as a smartphones' messaging application and its impact on improving two major KPIs, the impact on initial ER door to ECG time, and door to balloon time, in a predefined 6-month corrective action period.

Methods: Prospective, quality improvement plan was set to reduce door to first ECG and door to balloon times to less than 10 and 90 minutes, respectively in all ACS cases including STEMI, from August 2020 to April 30th, 2021. Read More

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Yoga for hypertensive patients: a study on barriers and facilitators of its implementation in primary care.

Glob Health Action 2021 Jan;14(1):1952753

Institute for Health and Sport, Victoria University, Melbourne, Australia.

Background: International guidelines for hypertension treatment recommend the use of yoga, particularly among low-risk patients. However, evidence is lacking on the implementation potential of health-worker-led yoga interventions in low-resource, primary care settings.

Objective: To assess barriers to and facilitators of the implementation of a yoga intervention for hypertensive patients in primary care in Nepal. Read More

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January 2021

The Effect of Social Isolation During the COVID-19 Pandemic on Patients with Chronic Low Back Pain Who Underwent a Spine Intervention.

Pain Physician 2021 Aug;24(5):319-325

University of Health Sciences, Gulhane School of Medicine, Department of PM&R, Gaziler Physical Therapy and Rehabilitation Training and Research Hospital, Ankara, Turkey.

Background: The COVID-19 infection poses a serious threat to global health for millions of people. In addition to therapeutic treatment methods, preventive measures are also important in controlling the pandemic. As a result, billions of people are quarantined in their homes to prevent the spread of coronavirus. Read More

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Cost-effectiveness of a mobile phone text messaging program (KIDNEYTEXT) targeting dietary behaviours in people receiving haemodialysis.

J Hum Nutr Diet 2021 Jul 29. Epub 2021 Jul 29.

Westmead Clinical School, The University of Sydney, NSW, Australia.

Background: There is little information available to inform the cost-effectiveness of eHealth interventions in improving patient health outcomes. A trial-based economic evaluation was undertaken in order to inform feasibility of conducting a mobile phone text messaging program targeting dietary behaviours in people receiving haemodialysis.

Methods: A trial-based economic evaluation from a health system perspective of a 6 month pilot randomised controlled trial was undertaken. Read More

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Assessment of healthcare worker's hand hygiene and infection prevention practices of their personal belongings in a healthcare setting: a survey in pre COVID-19 era and literature review on standard disinfection practices.

J Prev Med Hyg 2021 Mar 29;62(1):E104-E109. Epub 2021 Apr 29.

Department of Medicine, AIIMS, New Delhi.

Background: Healthcare workers' (HCW) hands and personnel belongings are vehicles of transmission of nosocomial infections. Knowledge, attitude, and practice of hand hygiene have been extensively studied suggesting adequate knowledge but poor compliance. Similar data on aprons, mobile phone and stethoscope disinfection practices are lacking. Read More

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Oversampling of Minority Populations Through Dual-Frame Surveys.

J Surv Stat Methodol 2021 Jun 11;9(3):626-649. Epub 2020 Jan 11.

Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Previous studies have shown disparities in health conditions and behaviors among different ethnic groups. Sampling designs that do not consider oversampling certain minority populations, such as American Indians or African Americans, may not produce sufficient sample sizes for estimating health parameters for minority populations. Oversampling is one of the most common approaches that researchers use to achieve required precision levels for small domain estimation. Read More

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Computer vision syndrome among Saudi population: An evaluation of prevalence and risk factors.

J Family Med Prim Care 2021 Jun 2;10(6):2313-2318. Epub 2021 Jul 2.

Department of Neurosurgery, King Fahad University Hospital, Imam Adulrahman bin Faisal University, Dammam, Saudi Arabia.

Introduction: In the recent era of technological evolution, electronic devices have become an essential part of our lives, not merely in professional work settings, but also in daily leisure activities. Although these devices have simplified our lives, they are associated with a wide variety of health complaints. Thus, the so-called computer vision syndrome (CVS) has become a growing public health problem and has gained significant attention as it plays an important role in the quality of life of each individual, which in turn has put an increased burden on the health care system. Read More

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Susceptibility to Scams in Older Black and White Adults.

Front Psychol 2021 12;12:685258. Epub 2021 Jul 12.

Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States.

Previous reports on racial differences in scam susceptibility have yielded mixed findings, and few studies have examined reasons for any observed race differences. Older Black and White participants without dementia ( = 592) from the Minority Aging Research Study and the Rush Memory and Aging Project who completed a susceptibility to scam questionnaire and other measures were matched according to age, education, sex, and global cognition using Mahalanobis distance. In adjusted models, older Black adults were less susceptible to scams than older White adults (Beta = -0. Read More

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Utilization, Barriers and Determinants of Emergency Medical Services in Mekelle City, Tigray, Ethiopia: A Community-Based Cross-Sectional Study.

Open Access Emerg Med 2021 22;13:325-334. Epub 2021 Jul 22.

Department of Nursing, College of Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia.

Background: Emergency medical services (EMS) are services that provide out-of-hospital emergency medical care to injured or ill peoples, and transporting to definitive care. EMS is an integral part of the emergency medical system and has been associated with decreased morbidity and mortality related to emergency cases. The aim of this study was to assess the utilization, barriers, and determinants of EMS in Mekelle, Ethiopia. Read More

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Modernizing Training in Psychotherapy Competencies With Adaptive Learning Systems: Proof of Concept.

Res Soc Work Pract 2021 Jan 13;31(1):90-100. Epub 2020 Oct 13.

Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.

Purpose: This proof-of-concept study assessed the feasibility, acceptability, and effectiveness of an intelligent tutoring system (ITS) as a classroom adjunct to improve training bachelor of social work (BSW) students in client engagement strategies.

Methods: We codeveloped the ITS with 11 undergraduate students and pilot tested it with six BSW students enrolled in a class on telephone-based cognitive behavioral therapy (tCBT). Student competencies in tCBT were assessed by expert review of role-plays. Read More

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January 2021

Overdose response among trained and untrained women with a history of illicit drug use: a mixed-methods examination.

Drugs (Abingdon Engl) 2021 16;28(4):328-339. Epub 2020 Sep 16.

Department of Community Health and Prevention, Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA.

Little is known about differences in bystander behavior among people who use drugs, trained and untrained in opioid overdose prevention. We examined three types of recommended overdose response - a 911 call, rescue breathing/CPR, and naloxone administration-among Philadelphia-based, predominantly street-involved women with a history of illicit drug use. The study utilized a convergent mixed methods approach integrating data from 186 quantitative survey responses and 38 semi-structured qualitative interviews. Read More

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September 2020

Five questions to consider when conducting COVID-19 phone research.

BMJ Glob Health 2021 Jul;6(Suppl 5)

Dalberg Global Development Advisors, Mumbai, Maharashtra, India.

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The impact of distance on post-ICU disability.

Aust Crit Care 2021 Jul 25. Epub 2021 Jul 25.

Australian and New Zealand Intensive Care Research Centre, Melbourne, Australia; The Alfred Hospital, Melbourne, Australia; Monash Partners Academic Health Science Centre, Australia. Electronic address:

Background: Nonurban residential living is associated with adverse outcomes for a number of chronic health conditions. However, it is unclear what effect it has amongst survivors of critical illness.

Objectives: The purpose of this study is to determine whether patients living greater than 50 km from the treating intensive care unit (ICU) have disability outcomes at 6 months that differ from people living within 50 km. Read More

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The impact of non-medical cannabis legalization and other exposures on retention in longitudinal cannabis research: a survival analysis of a prospective study of Canadian medical cannabis patients.

J Cannabis Res 2021 Jul 28;3(1):34. Epub 2021 Jul 28.

Department of Psychology, University of British Columbia, 3333 University Way, OkanaganKelowna, B.C, V1V 1V7, Canada.

Background: Despite repeated calls by medical associations to gather evidence on the harms and benefits of cannabis, there are ongoing methodological challenges to conducting observational and clinical studies on cannabis, including a high rate of patients that are lost to follow-up (LTFU). This study explores factors potentially associated with retention in a large prospective study of Canadian medical cannabis patients, with the goal of reducing the probability that patients will be lost to follow-up in future cannabis research.

Methods: The Tilray Observational Patient Study (TOPS) was a multi-site, prospective study assessing the impact of medical cannabis over 6 months in a broad population of authorized Canadian cannabis patients. Read More

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"At least someone thinks I'm doing well": a real-world evaluation of the quit-smoking app StopCoach for lower socio-economic status smokers.

Addict Sci Clin Pract 2021 Jul 28;16(1):48. Epub 2021 Jul 28.

Department of Behavioural Science and Health, University College London, London, UK.

Background: Smoking is more prevalent and persistent among lower socio-economic status (SES) compared with higher-SES groups, and contributes greatly to SES-based health inequities. Few interventions exist that effectively help lower-SES smokers quit. This study evaluated "De StopCoach", a mobile phone delivered eHealth intervention targeted at lower-SES smokers based on the evidence-based StopAdvisor, in a real-world setting (five municipalities) in The Netherlands in 2019-2020. Read More

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Resiliency Engagement and Care in Health (REaCH): a telephone befriending intervention for upskilled rural youth in the context of COVID-19 pandemic-study protocol for a multi-centre cluster randomised controlled trial.

Trials 2021 Jul 28;22(1):500. Epub 2021 Jul 28.

Rajagiri College of Social Sciences (Autonomous), Rajagiri P.O, Kalamassery, Cochin, Kerala, 683 104, India.

Background: The lockdown associated with the COVID-19 pandemic is likely to impact people's mental health, especially those from economically disadvantaged and vulnerable sections of society. Mental health can be affected by many factors, including fear of disease transmission, from response measures against the pandemic like social distancing, movement restriction, fear of being in quarantine, loneliness, depression due to isolation, fear of losing work and livelihood and avoiding health care due to fear of being infected. Telephonic befriending intervention by non-specialists will be used to provide social and emotional support to the youth from the Deen Dayal Upadhyaya Grameen Kaushalya Yojana (DDUGKY), an initiative of the Government of India. Read More

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Randomised study within a trial (SWAT) to evaluate personalised versus standard text message prompts for increasing trial participant response to postal questionnaires (PROMPTS).

Trials 2021 Jul 28;22(1):502. Epub 2021 Jul 28.

Centre for Rehabilitation Research in Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Background: Use of a person's name in a text message has been shown to be effective in instigating behaviour change. We evaluated the effectiveness of a personalised text message (including the recipient's name) versus a standardised text message for prompting a response from trial participants to complete and return postal follow-up questionnaires.

Methods: Using a randomised study within a trial (SWAT) embedded within the host GRASP (Getting it Right: Addressing Shoulder Pain) trial, participants who provided a mobile telephone number were randomised (1:1) by a central computer system to receive either (1) a personalised text message which included their name or (2) a standard text message. Read More

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Clinical analysis of redo aortic root replacement after cardiac surgery: a retrospective study.

J Cardiothorac Surg 2021 Jul 28;16(1):202. Epub 2021 Jul 28.

Department of Cardiovascular Surgery, Army Medical Center of PLA, Chongqing, 400020, China.

Objectives: To explore the etiology, previous cardiac procedure methods and outcomes of redo aortic root replacement after cardiac surgery.

Methods: A retrospective analysis of 41 patients who underwent aortic root replacement surgery in our hospital from February 2010 to February 2020 who underwent at least one cardiac surgery in the past, including 27 males and 14 females, with an average age of 49.5 ± 10. Read More

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