2,108,505 results match your criteria study area


The relationship between density of drug outlets, crime hot spots and family factors on the consumption of drugs and delinquent behaviour of male adolescent Mexican students.

Soc Sci Med 2021 May 4;279:113985. Epub 2021 May 4.

Public Health Department, Medicine School, Autonomous University of San Luis Potosi, Av. Venustiano Carranza 2405, Col. Los Filtros, zip code, 78210, San Luis Potosí, Mexico. Electronic address:

This study examined the relationship between community risk factors (drug outlets density and crime hot spots) and family factors on the risk behaviours (drugs consumption and delinquent behaviour) of male adolescent Mexican students. Results were obtained based on data bank analysis and direct collection of information regarding family factors and risk behaviours of adolescents attending school. Spatial and statistical analysis was performed. Read More

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Spider web biomonitoring: A cost-effective source apportionment approach for urban particulate matter.

Environ Pollut 2021 May 8;286:117328. Epub 2021 May 8.

Institute of Geosciences, Friedrich Schiller University Jena, Burgweg 11, 07749, Jena, Germany. Electronic address:

Elevated levels of particulate matter (PM) in urban atmospheres are one of the major environmental challenges of the Anthropocene. To effectively lower those levels, identification and quantification of sources of PM is required. Biomonitoring methods are helpful tools to tackle this problem but have not been fully established yet. Read More

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Mesoporous cellulose-chitosan composite hydrogel fabricated via the co-dissolution-regeneration process as biosorbent of heavy metals.

Environ Pollut 2021 May 7;286:117324. Epub 2021 May 7.

Department of Biological Systems Engineering, University of Wisconsin-Madison, 460 Henry Mall, Madison, WI, 53706, USA. Electronic address:

Developing low-cost and high-performance biosorbent for water purification continues drawing more and more attention. In this study, cellulose-chitosan composite hydrogels were fabricated via a co-dissolution and regeneration process using a molten salt hydrate (a 60 wt% aqueous solution of LiBr) as a solvent. The addition of chitosan not only introduced functionality for metal adsorption but also increased the specific surface area and improved the mechanical strength of the composite hydrogel, compared to pure cellulose hydrogel. Read More

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Cognitive impairment and consumption of mental healthcare resources in outpatients with bipolar disorder.

J Psychiatr Res 2021 May 7;138:535-540. Epub 2021 May 7.

Teaching Unit of Psychiatry, Department of Medicine, University of Valencia, Valencia, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII., Avenida Blasco Ibáñez 15, 46010, Valencia, Spain. Electronic address:

Cognitive dysfunction is a major predictor of functional outcomes, and loss of occupational functioning is usually linked with a higher cost of illness. However, the association between cognitive impairment and consumption of health resources has not been studied in bipolar disorder to date. This study aims to examine this relationship. Read More

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The effect of the birth method on changes of the prepartum and postpartum dimensions of perineal body.

Eur J Obstet Gynecol Reprod Biol 2021 May 5;262:36-39. Epub 2021 May 5.

Ministry of Health Ankara City Hospital, Department of Obstetrics and Gynecology, Turkey.

Objective: The perineal body is critical for maintaining the integrity of the pelvic floor, especially in females as it can be injured during vaginal delivery. This study aimed to evaluate the effect of childbirth on perineal body dimensions by using a transperineal 2D ultrasound.

Study Design: This prospective cohort study was performed in a tertiary obstetric care center. Read More

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Understanding the mechanisms of groundwater recharge and flow in periglacial environments: New insights from the Ledo-Paniselian aquifer in Belgium.

J Contam Hydrol 2021 May 4;241:103819. Epub 2021 May 4.

Laboratory for Applied Geology and Hydrogeology, Department of Geology, Ghent University, Krijgslaan 281-S8, B-9000 Gent, Belgium.

The Ledo-Paniselian aquifer in Belgium has been proposed to offer unique opportunities to study groundwater recharge and flow in periglacial conditions during the Last Glacial Maximum (LGM), due to its location in the permanent permafrost area, south of the ice sheet at that time. A palaeoclimatic record had been set up previously for this aquifer, consisting of major ion chemistry, stable isotopes, radiocarbon and noble gases. In this paper, methane data have been used to further refine the paleoclimatic model, along with revisiting in detail the set of chemical data, focusing on the area where groundwaters, recharged around the LGM, are known to occur. Read More

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Measuring the spatiotemporal evolution of accident hot spots.

Accid Anal Prev 2021 May 11;157:106133. Epub 2021 May 11.

Department of Civil & Environmental Engineering, E2509 Thomas & Nell Lafferre Hall, University of Missouri, Columbia, MO, 65211, USA; Department of Geography, 220 Stewart Hall, University of Missouri, Columbia, MO, USA; Institute for Data Science and Informatics, University of Missouri, Columbia, MO, USA. Electronic address:

One reality of transportation systems is that vehicular accidents can happen practically anywhere and at any time. An increasing body of research suggests though that spatial and/or temporal dependencies (i.e. Read More

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Greenspace exposure and cancer incidence: A 27-year follow-up of the French GAZEL cohort.

Sci Total Environ 2021 May 6;787:147553. Epub 2021 May 6.

Univ. Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France. Electronic address:

Background: Greenspace exposure has been suggested to be associated with a range of health outcomes. The available evidence on the association of this exposure with cancer is still very scarce and inconsistent.

Objectives: We aimed to study the association between greenspace exposure and all-site and site-specific (prostate, breast, colorectal, bladder, lung, and malignant melanoma of skin) cancer incidence in the GAZEL cohort. Read More

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The implications of facility design and enabling policies on the economics of dry anaerobic digestion.

Waste Manag 2021 May 11;128:122-131. Epub 2021 May 11.

Energy Technologies Area, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, United States; Biosciences Area, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, United States; Joint BioEnergy Institute, 5885 Hollis Street, Emeryville, CA 94720, United States.

Diverting organic waste from landfills provides significant emissions benefits in addition to preserving landfill capacity and creating value-added energy and compost products. Dry anaerobic digestion (AD) is particularly attractive for managing the organic fraction of municipal solid waste because of its high-solids composition and minimal water requirements. This study utilizes empirical data from operational facilities in California in order to explore the key drivers of dry AD facility profitability, impacts of market forces, and the efficacy of policy incentives. Read More

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Treatment planning factors associated with long-term outcomes of Gamma Knife surgery in patients with trigeminal neuralgia.

World Neurosurg 2021 May 11. Epub 2021 May 11.

Department of Neurosurgery, Seoul National University Hospital, Seoul, Republic of Korea; GammaKnife Radiosurgery Center, Seoul National University Hospital, Seoul, Republic of Korea; Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: Gamma Knife surgery (GKS) is an established treatment option for trigeminal neuralgia (TN). However, the long-term efficacy of GKS for patients with TN has not been well-studied. The aim of the study is to evaluate the sequential course of pain control after GKS and analyze the factors associated with the long-term analgesic effect, focusing on radiation dosimetry and neurovascular conflict (NVC) factors. Read More

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Clinical prediction of extra-medical use of prescription pain relievers from a representative United States sample.

Prev Med 2021 May 11:106610. Epub 2021 May 11.

Departments of Psychiatry and of Child Study, Yale School of Medicine, United States of America. Electronic address:

Use of prescription opioids 'beyond the bounds' of medical guidance can lead to opioid dependence. Yet recent efforts to predict extra-medical use of prescription pain relievers (EMPPR) have relied on electronic medical or pharmacy records. Because peak incidence of EMPPR occurs during adolescence- a time of relative health- administrative data may be inadequate. Read More

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SOX9 promotes epidermal growth factor receptor-tyrosine kinase inhibitor resistance via targeting β-catenin and epithelial to mesenchymal transition in lung cancer.

Life Sci 2021 May 11:119608. Epub 2021 May 11.

Cancer Drug Resistance Laboratory, Department of Life Science, National Institute of Technology Rourkela, Odisha 769008, India. Electronic address:

Aims: The first-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), gefitinib, continues to be a primary treatment option for lung cancer patients. However, acquisition of resistance to gefitinib is a major obstacle in lung cancer treatment and its cause is poorly understood. The present study aimed to implicate the role of SOX9-β-catenin in developed resistance to gefitinib through epithelial to mesenchymal transition (EMT) in lung cancer in vitro and ex vitro. Read More

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Metal pollution of soil, plants, feed and food in the Niger Delta, Nigeria: Health risk assessment through meat and fish consumption.

Environ Res 2021 May 11:111273. Epub 2021 May 11.

African Centre of Excellence for Public Health and Toxicological Research (ACE-PUTOR); Department of Experimental Pharmacology & Toxicology, Faculty of Pharmacy, University of Port Harcourt, Rivers State, Nigeria.University of Port Harcourt, PMB, 5323 Port Harcourt, Rivers State, Nigeria. Electronic address:

This study was aimed at determining mainly the concentrations of As and other metals (Cd, Cu, Hg, Pb, V and Zn) in samples of feed, soil, plants and foods (fish, chicken, goat and cow meat) grown and consumed in six areas of Niger Delta, Nigeria (Choba, Khana, Trans Amadi, Eleme, Uyo and Yenagoa). Principal Component Analysis (PCA) models were used for identifying groups of variables (i.e. Read More

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Serum phospholipids are potential biomarkers for early diagnosis of gastric cancer.

Clin Chim Acta 2021 May 11. Epub 2021 May 11.

Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. Electronic address:

Background And Aims: Early diagnosis is key to improving the prognosis of gastric cancer. Altered phospholipid metabolism has been observed in different types of cancer. This study assessed serum phospholipid levels of patients with gastric cancer to explore biomarkers for its early diagnosis. Read More

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Tools to assess the Risk of bias and Reporting Quality of Randomized Controlled Trials in Rehabilitation.

Arch Phys Med Rehabil 2021 May 11. Epub 2021 May 11.

Cochrane Rehabilitation; IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy; Physical and Rehabilitation Medicine, University "La Statale", Milan, Italy.

Objective: to determine whether new tools and items have been developed to evaluate the risk of bias (RoB) and reporting of Randomized Controlled Trials (RCTs) in rehabilitation area; to determine which items are included in the existing reporting guidelines, and to create a matrix of items to report and conduct trials in rehabilitation as the first step for a starting a rigorous validation process.

Data Sources: Searches were conducted in MEDLINE, EMBASE, and CINAHL databases.

Study Selection: Studies should describe a newly developed tool to evaluate the RoB or quality of reporting for RCTs in the area of rehabilitation. Read More

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Discerning perturbed assembly of lipids in a model membrane in presence of violacein.

Biochim Biophys Acta Biomembr 2021 May 11:183647. Epub 2021 May 11.

Department of Physics, School of Natural Sciences, Shiv Nadar University, NH 91, Tehsil Dadri, G. B. Nagar, Uttar Pradesh 201314, India. Electronic address:

Violacein is a naturally found pigment that is used by some gram negative bacteria to defend themselves from various gram positive bacteria. As a result, this molecule has caught attention for its potential biomedical applications and has already shown promising outcomes as an antiviral, antibacterial, and anti-tumor agent. Understanding the interaction of this molecule with a cellular membrane is an essential step to extend its use in the pharmaceutical paradigm. Read More

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Genome-informed approach to identify genetic determinants of Flavobacterium psychrophilum phage susceptibility.

Environ Microbiol 2021 May 14. Epub 2021 May 14.

Marine Biological Section, Department of Biology, University of Copenhagen, Helsingør, Denmark.

The fish pathogen Flavobacterium psychrophilum infects farmed salmonids worldwide, and application of bacteriophages has been suggested for controlling disease outbreaks in aquaculture. Successful application of phages requires detailed knowledge about the variability in phage susceptibility of the host communities. In this study we analyzed the genetic diversity of F. Read More

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Determinants of healthcare worker turnover in intensive care units: A micro-macro multilevel analysis.

PLoS One 2021 14;16(5):e0251779. Epub 2021 May 14.

Modélisation Epidémiologie et Surveillance des Risques Sanitaires (MESuRS) Laboratory, Conservatoire National des Arts et Métiers (Cnam), Paris, France.

Background: High turnover among healthcare workers is an increasingly common phenomenon in hospitals worldwide, especially in intensive care units (ICUs). In addition to the serious financial consequences, this is a major concern for patient care (disrupted continuity of care, decreased quality and safety of care, increased rates of medication errors, …).

Objective: The goal of this article was to understand how the ICU-level nurse turnover rate may be explained from multiple covariates at individual and ICU-level, using data from 526 French registered and auxiliary nurses (RANs). Read More

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Artificial intelligence for classifying uncertain images by humans in determining choroidal vascular running pattern and comparisons with automated classification between artificial intelligence.

PLoS One 2021 14;16(5):e0251553. Epub 2021 May 14.

Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Purpose: Abnormalities of the running pattern of choroidal vessel have been reported in eyes with pachychoroid diseases. However, it is difficult for clinicians to judge the running pattern with high reproducibility. Thus, the purpose of this study was to compare the degree of concordance of the running pattern of the choroidal vessels between that determined by artificial intelligence (AI) to that determined by experienced clinicians. Read More

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Incidence and predictors of mortality within the first year of antiretroviral therapy initiation at Debre-Markos Referral Hospital, Northwest Ethiopia: A retrospective follow up study.

PLoS One 2021 14;16(5):e0251648. Epub 2021 May 14.

Department of Anesthesiology, College of Medicine and Health Science, Debre-Tabor University, Debre-Tabor, Ethiopia.

Background: Acquired Immunodeficiency Syndrome (AIDS) is one of the most fatal infectious diseases in the world, especially in Sub-Saharan Africa, including Ethiopia. Even though Antiretroviral therapy (ART) significantly decreases mortality overall, death rates are still highest especially in the first year of ART initiation.

Objective: To assess the incidence and predictors of mortality within the first year of ART initiation among adults on ART at Debre-Markos Referral Hospital, Northwest Ethiopia. Read More

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Hunter-Gatherers in context: Mammal community composition in a northern Tanzania landscape used by Hadza foragers and Datoga pastoralists.

PLoS One 2021 14;16(5):e0251076. Epub 2021 May 14.

Department of Human Behavior, Ecology and Culture, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

In many regions of sub Saharan Africa large mammals occur in human-dominated areas, yet their community composition and abundance have rarely been described in areas occupied by traditional hunter-gatherers and pastoralists. Surveys of mammal populations in such areas provide important measures of biodiversity and provide ecological context for understanding hunting practices. Using a sampling grid centered on a Hadza hunter-gatherer camp and covering 36 km2 of semi-arid savannah in northern Tanzania, we assessed mammals using camera traps (n = 19 stations) for c. Read More

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Prognostic value of pre-treatment systemic immune-inflammation index in patients with endometrial cancer.

PLoS One 2021 14;16(5):e0248871. Epub 2021 May 14.

Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Nara, Japan.

Background: The systemic immune-inflammation index (SII), which is calculated using absolute platelet, neutrophil, and lymphocyte counts, has recently attracted attentions as a prognostic indicator in patients with solid malignancies. In the current study, we retrospectively investigated the prognostic significance of pre-treatment SII among patients with endometrial cancer.

Method: Endometrial cancer patients treated at Nara medical university hospital between 2008 and 2018 were included in the current study. Read More

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Isolation and identification of naphthalene degrading bacteria and their degradation characteristics under rainwater environment in heavily polluted areas.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2021 ;56(4):434-444

School of Environmental and Municipal Engineering, Tianjin Chengjian University, Tianjin, China.

This study is screened for naphthalene degrading strains from a heavily polluted area with high naphthalene concentration in the rainwater for the effective removal of naphthalene from rainwater. Recently, naphthalene biodegradation has been achieved in water. However, the influences of organics and inorganics in the rainwater on the biodegradation of naphthalene remains unclear. Read More

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January 2021

Effect of Exercise Intensity on the Healing of the Bone-Tendon Interface: A Mouse Rotator Cuff Injury Model Study.

Am J Sports Med 2021 May 14:3635465211011751. Epub 2021 May 14.

Department of Sports Medicine & Research Centre of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.

Background: Injuries at the bone-tendon interface (BTI) are common findings in clinical practice. Rehabilitation procedures after BTI surgery are important but are controversial.

Purpose: To investigate the effects of different exercise intensities on BTI healing by means of an established mouse rotator cuff injury model. Read More

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Evaluation the Effects of Subsp. on an In-Vitro Wound Model Using Human Dermal Fibroblast Cells.

Int J Low Extrem Wounds 2021 May 14:15347346211016693. Epub 2021 May 14.

37503Atatürk University, Erzurum, Turkey.

Wound is tissue damage that occurs in the skin. species (Altınotu) are rich in phenolic compounds used in traditional medicine for wound healing. The main component in their flower head (capitulum) is phenolic compounds. Read More

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Viewing patterns regarding panoramic radiographs with different pathological lesions: an eye-tracking study.

Dentomaxillofac Radiol 2021 May 14:20210019. Epub 2021 May 14.

Department of Oral and Maxillofacial and Plastic Surgery, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

Objective: The aim of this study was to examine how dental students vary their viewing patterns of panoramic radiographs during different levels of dental education.

Methods: Two groups of students (total number = 48, = 24) in different grades (second and fifth clinical semester) were compared. The second clinical semester participated twice, as during the second clinical semester a specific lecture on dental radiology and diagnosis is held. Read More

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Using Prescription and Wastewater Data to Estimate the Correction Factors of Atenolol, Carbamazepine, and Naproxen for Wastewater-Based Epidemiology Applications.

Environ Sci Technol 2021 May 14. Epub 2021 May 14.

Queensland Alliance for Environmental Health Sciences, The University of Queensland, 20 Cornwall Street, Woolloongabba, 4102 Brisbane, Australia.

The correction factor (CF) is a critical parameter in wastewater-based epidemiology (WBE) that significantly influences the accuracy of the final consumption estimates. However, most CFs have been derived from a few old pharmacokinetic studies and should be re-evaluated and refined to improve the accuracy of the WBE approach. This study aimed to review and estimate the CFs for atenolol, carbamazepine, and naproxen for WBE using the daily mass loads of those pharmaceuticals in wastewater and their corresponding dispensed prescription data in Australia. Read More

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Percutaneous Vertebroplasty Versus Kyphoplasty for Thoracolumbar Osteoporotic Vertebral Compression Fractures in Patients with Distant Lumbosacral Pain.

Pain Physician 2021 May;24(3):E349-E356

Department of Spinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Background: In clinical practice, we have found that the pain caused by thoracolumbar osteoporotic vertebral compression fracture (OVCF) is sometimes not limited to the level of the fractured vertebrae but instead occurs in areas far away from the injured vertebrae, such as the lower back, area surrounding the iliac crest, or buttocks, and this type of pain is known as distant lumbosacral pain. The pathogenesis of pain in distant regions caused by thoracolumbar OVCF remains unclear.

Objectives: To compare the clinical efficacy and imaging outcomes of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of distant lumbosacral pain accompanied by thoracolumbar OVCF and to explore the possible pathogenesis of distant lumbosacral pain caused by thoracolumbar OVCF. Read More

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Pathomechanism of Lower-level Discogenic Groin Pain and Clinical Outcomes of Percutaneous Endoscopic Discectomy for the Treatment of Discogenic Groin Pain.

Pain Physician 2021 May;24(3):E289-E297

The First Affiliated Hospital of Harbin Medical University, Nangang, Harbin, P.R. China.

Background: Groin pain can be induced by high-level (L1-L2 or L2-L3) lumbar disc herniation. However, 4.1% of patients with lower-level (L4-L5 or L5-S1) lumbar disc herniation also complained of groin pain. Read More

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