96,402 results match your criteria studied works

Fluorescent detection mechanism of CO-releasing molecule-3: Competition of inter-/intra-molecular hydrogen bonds.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jul 26;263:120227. Epub 2021 Jul 26.

Henan Key Laboratory of Infrared Materials & Spectrum Measures and Applications, School of Physics, Henan Normal University, Xinxiang 453007, China. Electronic address:

The fluorescent detection mechanism of 2-(4-nitro-1,3-dioxoisoindolin-2-yl) acetic acid (CORM3-green) on CO-Releasing Molecule-3 (CORM-3) is theoretically studied. Upon reaction with CORM-3, the non-fluorescent CORM3-green is transferred to the keto form of 2-(4-amino-1,3-dioxoisoindolin-2-yl)acetic acid (PTI) to produce strong fluorescence peak located at 423 nm. This peak red-shifts to 489 nm, which is induced by the strengthening of intermolecular hydrogen bond (HB) between PTI and water molecules and attributed to the experimentally observed fluorescence emission at 503 nm. Read More

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A temperature-dependent Raman scattering and X-ray diffraction study of KMoO·HO and ab initio calculations of KMoO.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jul 16;263:120184. Epub 2021 Jul 16.

Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará, CEP 66075-110, Belém, PA, Brazil.

This study reports a temperature-dependent Raman scattering and X-ray diffraction study of KMoO·HO. The high-temperature Raman scattering analysis shows that the material remains structurally stable, with triclinic symmetry, in a temperature range from 300 to 413 K and undergoes a structural phase transition between 413 and 418 K. This phase transition is most likely connected with the dehydration process of KMoO·HO. Read More

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Dynamics of left ventricular myocardial work in patients hospitalized for acute heart failure.

J Card Fail 2021 Jul 28. Epub 2021 Jul 28.

Comprehensive Heart Failure Center, University Hospital and University of Würzburg, Würzburg, Germany; Department of Medicine I, University Hospital Würzburg, Würzburg, Germany. Electronic address:

Aims: . Left ventricular ejection fraction is the most commonly used measure describing pumping efficiency, but it is heavily dependent on loading conditions and therefore not well suited to study pathophysiologic changes. The novel concept of echocardiography-derived myocardial work (MyW) overcomes this disadvantage as it is based on left ventricular (LV) pressure-strain loops. Read More

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Rare-earth nanoparticles induce depression, anxiety-like behavior, and memory impairment in mice.

Food Chem Toxicol 2021 Jul 28:112442. Epub 2021 Jul 28.

Department of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, 350100, China.

Rare-earth nanoparticles have been widely studied for disease diagnosis, in vivo optical imaging, biosensing, and drug delivery. However, the effects of rare-earth nanoparticles on a central nervous system remain unclear. Here, we report that the continuous exposure to rare-earth nanoparticles in mice can cause behavioral alterations including cognitive deficits, anxiety, and depression-like behavior. Read More

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Proximity of schools to roads and students' academic performance: A cross-sectional study in the Federal District, Brazil.

Environ Res 2021 Jul 28:111770. Epub 2021 Jul 28.

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Investigations of the educational implications of children's exposure to air pollutants at school are crucial to enhance our understanding of the hazards for children. Most of the existing literature is based on studies performed in North America and Europe. Further investigation is required in low- and middle-income countries, where there are important challenges related to public health, transportation, environment, and education sector. Read More

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Efficient and selective removal of Ag as nano silver particles by the composite of SiO supported nano ferrous oxalate.

Environ Res 2021 Jul 28:111696. Epub 2021 Jul 28.

School of Minerals Processing and Bioengineering, Central South University, Changsha, 410083, China; Faculty of Materials Metallurgy & Chemistry, Jiangxi University of Science & Technology, Ganzhou, Jiangxi, 341000, China. Electronic address:

Developing novel environmentally materials with high capacity and selectivity for Ag adsorption by transforming Ag to nano silver is important for the recovery of precious metals from Ag-containing solution. The present study systematically studied the Ag  adsorption process from solution by the composite of SiO supported nano ferrous oxalate (SNFO) synthesized from biotite-containing minerals. Batch experiments, dynamics and isothermal adsorption fitting results showed that Ag removal behaviours were in accordance with the pseudo-first-order kinetic model and Langmuir model, and the maximal Ag removal capacity was 223. Read More

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Near-infrared emissive polymer coated IR-820 nanoparticles assisted photo-thermal therapy for cervical cancer cells.

J Biophotonics 2021 Jul 31:e202100117. Epub 2021 Jul 31.

State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, School of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, China.

Photo-thermal therapy (PTT) has attracted wide attention due to its non-invasiveness and its thermal ablation ability. As photo-thermal agents are crucial factor in PTT, those with the characteristics of biocompatibility, non-toxicity and high photo-thermal stability have attracted great interest. In this work, new indocyanine green (IR-820) was utilized as a photo-thermal agent and near infrared (NIR) fluorescence imaging nanoprobe. Read More

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Energetic and electronic properties of NH, NO and SO interacting with GaN nanotube: a DFT study.

J Mol Model 2021 Jul 30;27(8):234. Epub 2021 Jul 30.

Departamento de Física, Universidade Federal do Maranhão, 65080-805, São Luís, MA, Brazil.

In this work, the interaction of GaN nanotube (GaNNT) with common air pollutants of industrialized cities, such as NH, NO and SO in different configurations was studied. For this study, the single-walled (10,0) GaNNT was used. The analysis was done via the density functional theory implemented in the SIESTA simulation software. Read More

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Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia.

Blood Cancer J 2021 Jul 30;11(7):136. Epub 2021 Jul 30.

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.

B-cell chronic lymphocytic leukaemia (CLL) is associated with immunosuppression and patients are at increased clinical risk following SARS-CoV-2 infection. Covid-19 vaccines offer the potential for protection against severe infection but relatively little is known regarding the profile of the antibody response following first or second vaccination. We studied spike-specific antibody responses following first and/or second Covid-19 vaccination in 299 patients with CLL compared with healthy donors. Read More

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Diabetes mellitus and cardiovascular risk: an update of the recommendations of the Diabetes and Cardiovascular Disease Working Group of the Spanish Society of Diabetes (SED, 2021).

Clin Investig Arterioscler 2021 Jul 27. Epub 2021 Jul 27.

Servicio de Endocrinología y Nutrición, Hospital Puerta del Mar, Cádiz, España.

This document is an update to the clinical practice recommendations for the management of cardiovascular risk factors (CVRF) in diabetes mellitus. The consensus has been developed by a multidisciplinary team made up of members of the Cardiovascular Risk Group of the Spanish Diabetes Society (SED). The work is a necessary update as, since the last review three years ago, there have been many clinical trials that have studied the cardiovascular outcomes of numerous drugs in the diabetic population. Read More

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Fluorescence "turn-off/turn-on" biosensing of metal ions by gold nanoclusters, folic acid and reduced graphene oxide.

Anal Chim Acta 2021 Aug 10;1175:338745. Epub 2021 Jun 10.

Nanotechnology Research Group, Centre of Nanotechnology and Advanced Materials, University of Nottingham Malaysia, 43500, Semenyih, Selangor, Malaysia. Electronic address:

Metal ions homeostasis plays an important role in biological processes. The ability to detect the concentration of metal ions in biological fluids is often challenged by the obvious interference or competitive binding nature of other alkaline metals ions. Common analytical techniques employed for metal ions detection are electrochemical, fluorescence and colorimetric methods. Read More

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Construction and evaluation of an α-particle-irradiation exposure apparatus.

Int J Radiat Biol 2021 Jul 30:1-35. Epub 2021 Jul 30.

Department of Physics, School of Applied Mathematics and Physical Sciences, National Technical University of Athens (NTUA), Athens, 15780, Greece University, City, Country.

Purpose: The development of an exposure apparatus for in situ α-irradiation studies of cells. The construction of the apparatus is simple and the apparatus is maintenance free, easy to use and of low cost. This small device can be placed in an incubator, where the exposure environment is controlled. Read More

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Efficient removal of organic pollutants by a Co/N/S-doped yolk-shell carbon catalyst via peroxymonosulfate activation.

J Hazard Mater 2021 Jul 23;421:126726. Epub 2021 Jul 23.

School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116, PR China.

Carbon-based catalysts with heteroatom doping and hollow structures are desired for advanced oxidation processes (AOPs). Herein, dual-shelled Co, N, and S codoped hollow carbon nanocages were developed by wrapping zeolitic imidazolate framework-67 (ZIF-67) with trithiocyanuric acid (TCA) and performing subsequent carbonization. The optimal composite catalyst (Co-NC-CoS) exhibited excellent catalytic performance toward different organic pollutants. Read More

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Comparison of surfactant mass transfer with drop formation times from dynamic interfacial tension measurements in microchannels.

J Colloid Interface Sci 2021 Jul 16;605:204-213. Epub 2021 Jul 16.

ThAMeS Multiphase, Department of Chemical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK. Electronic address:

Dynamic interfacial tension was studied experimentally during drop formation in a flow-focusing microchannel. A low viscosity silicone oil (4.6 mPa s) was the continuous phase and a mixture of 48% w/w water and 52% w/w glycerol was the dispersed phase. Read More

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Synthesis of hypercrosslinked polymers for efficient solid-phase microextraction of polycyclic aromatic hydrocarbons and their derivatives followed by gas chromatography-mass spectrometry determination.

J Chromatogr A 2021 Jul 22;1653:462428. Epub 2021 Jul 22.

College of Science, Hebei Agricultural University, Baoding 071001, China; College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China. Electronic address:

Three novel hypercrosslinked polymers (HCPs) were synthesized via Friedel-Crafts reaction employing 1,3,5-tris(bromomethyl)-2,4,6-trimethylbenzene as alkylating agent, and triphenylbenzene, tetraphenylethylene and p-quaterphenyl as the aromatic units, respectively. The prepared HCPs were applied as solid-phase microextraction coatings for direct immersion extraction of polycyclic aromatic hydrocarbons (PAHs) and their oxygenated and nitrated derivatives in environmental water samples. The key factors affecting the extraction efficiency including extraction time, extraction temperature, stirring rate, ionic strength and desorption conditions, were carefully studied. Read More

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Development and frozen-thawed transfer of non-pronuclear zygotes-derived embryos in IVF cycles.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 22;264:206-211. Epub 2021 Jul 22.

Medical Center for Human Reproduction, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. Electronic address:

Objective: To explore the development and pregnancy potential of non-pronuclear (0PN) zygote-derived embryos in conventional in vitro fertilization (IVF) cycles.

Study Design: Embryonic development in 1039 oocyte retrieval cycles and clinical outcomes of 659 frozen-thawed blastocyst transfer cycles were retrospectively studied.

Results: Developmental potential of embryos with different blastomere numbers on day 3 were inconsistent in 0PN and 2PN groups. Read More

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Biomarker-based assessment of sublethal toxicity of organic UV filters (ensulizole and octocrylene) in a sentinel marine bivalve Mytilus edulis.

Sci Total Environ 2021 Jul 26;798:149171. Epub 2021 Jul 26.

Department of Marine Biology, Institute for Biological Sciences, University of Rostock, Rostock, Germany; Department of Maritime Systems, Interdisciplinary Faculty, University of Rostock, Rostock, Germany. Electronic address:

The global occurrence of organic UV filters in the marine environment is of increasing ecotoxicological concern. Here we assessed the toxicity of UV filters ensulizole and octocrylene in the blue mussels Mytilus edulis exposed to 10 or 100 μg l of octocrylene and ensulizole for two weeks. An integrated battery of biochemical and molecular biomarkers related to xenobiotics metabolism and cellular toxicity (including oxidative stress, DNA damage, apoptosis, autophagy and inflammation) was used to assess the toxicity of these UV filters in the mussels. Read More

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Fine cocoa beans production: Tracking aroma precursors through a comprehensive analysis of flavor attributes formation.

Food Chem 2021 Jul 19;365:130627. Epub 2021 Jul 19.

Corporación Colombiana de Investigación Agropecuaria (Agrosavia), Process & Quality Cocoa Laboratory. Centros de Investigación Palmira, Tibaitatá y La Selva - Km 14 Mosquera-Bogotá, Cundinamarca, P.O. Box 344300, Colombia; Centre de Coopération Internationale en Recherche Agronomique pour le Développement- CIRAD, UMR QualiSud, 1101 avenue Agropolis, CS 24501, 34093. Montpellier Cedex 5, Francia; UMR QualiSud, Univ Montpellier, CIRAD, Montpellier SupAgro, Univ Avignon, Univ La Reunion, Montpellier, France.

The fine flavor cocoa (FFC) market offers cocoa farmers better monetary and nonmonetary benefits than the bulk market. In this work, during cocoa fermentation, flavor formation was studied at different fermentation times based on sensory profiles, volatile compound contents and untargeted metabolomics. It was observed that chocolate quality is influenced by fermentation time. Read More

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Real-time monitoring of active caspase 3 during AFB1 induced apoptosis based on SERS-fluorescent dual mode signals.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jul 17;263:120195. Epub 2021 Jul 17.

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, PR China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, PR China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, PR China; Collaborative Innovation Center of Food Safety And Quality Control in Jiangsu Province, Jiangnan University, Wuxi 214122, PR China. Electronic address:

Aflatoxin B1 (AFB1) is the most toxic mycotoxin. Usually, the toxin activated apoptosis is considered mostly through intrinsic mitochondrial pathway while the caspase family as promoter and executor plays a crucial role. In this paper, a real-time and in situ detection of caspase 3 in living cells based on SERS-fluorescence dual mode nanosensor was studied. Read More

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Mechanical property gradients of taenioglossan radular teeth are associated with specific function and ecological niche in Paludomidae (Gastropoda: Mollusca).

Acta Biomater 2021 Jul 27. Epub 2021 Jul 27.

Functional Morphology and Biomechanics, Zoological Institute, Christian-Albrechts-Universität zu Kiel, Am Botanischen Garten 9, 24118 Kiel, Germany; Department of Mammalogy and Palaeoanthropology, Center of Natural History (CeNak), Universität Hamburg, Martin-Luther-King-Platz 3, 20146 Hamburg, Germany. Electronic address:

Biological tissues may exhibit graded heterogeneities in structure and mechanical properties that are crucial to their function. One biological structure that shows variation in both structure and function is the molluscan radula: the organ comprises a chitinous membrane with embedded teeth and serves to process and gather food. The tooth morphologies had been well studied in the last decades, but the mechanical properties of the teeth are not known for the vast majority of molluscs. Read More

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Pharmacokinetic herb-disease-drug interactions: Effect of ginkgo biloba extract on the pharmacokinetics of pitavastatin, a substrate of Oatp1b2, in rats with non-alcoholic fatty liver disease.

J Ethnopharmacol 2021 Jul 27:114469. Epub 2021 Jul 27.

Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300250, China. Electronic address:

Ethnopharmacological Relevance: Ginkgo biloba L. is a traditional Chinese medicine for hyper lipaemia. Ginkgo flavonols and terpene lactones are responsible for the lipid-lowering effect in non-alcoholic fatty liver disease (NAFLD). Read More

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Effects of new antiseizure drugs on seizure activity and anxiety-like behavior in adult zebrafish.

Toxicol Appl Pharmacol 2021 Jul 27:115655. Epub 2021 Jul 27.

Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Maria Curie-Sklodowska University, Akademicka 19, PL 20-033 Lublin, Poland. Electronic address:

Several studies with larvae and adult zebrafish have shown that old and new antiseizure drugs (ASDs) produce discrepant results in seizure tests, locomotor activity or anxiety models. In this study, the pentylenetetrazole seizure test (PTZ) was performed to assess the effectiveness of four new ASDs: lamotrigine (LTG), topiramate (TPM), felbamate (FBM), and levetiracetam (LEV) in the subsequent stages of seizures in adult fish. All ASDs were administered intraperitoneally (i. Read More

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Molecular-Scale Chemical Imaging of the Orientation of an On-Surface Coordination Complex by Tip-Enhanced Raman Spectroscopy.

J Am Chem Soc 2021 Jul 30. Epub 2021 Jul 30.

Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir-Prelog-Weg 3, Zurich CH-8093, Switzerland.

Metal-organic coordination structures at interfaces play an essential role in many biological and chemical systems. Understanding the molecular specificity, orientation, and spatial distribution of the coordination complexes at the nanometer scale is of great importance for effective molecular engineering of nanostructures and fabrication of functional devices with controllable properties. However, fundamental properties of such coordination systems are still rarely studied directly. Read More

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Effect of prone and supine positioning on the diaphragmatic work of breathing in convalescent preterm infants.

Pediatr Pulmonol 2021 Jul 30. Epub 2021 Jul 30.

Neonatal Intensive Care Centre, King's College Hospital NHS Foundation Trust, London, UK.

Objectives: To compare the work of breathing in the prone and supine positions in convalescent prematurely born infants.

Working Hypothesis: The work of breathing would be lower in the prone compared to the supine position.

Study Design: Prospective observational cohort study. Read More

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SARS-CoV-2 normalized viral loads and subgenomic RNA detection as tools for improving clinical decision-making and work reincorporation.

J Infect Dis 2021 Jul 30. Epub 2021 Jul 30.

Department of Microbiology, Hospital Clínic of Barcelona. Institut of Global Health (ISGlobal), Barcelona, Spain.

Background: SARS-CoV-2 RT-PCR provides a highly variable cycle-threshold (Ct) value that cannot distinguish viral infectivity. Subgenomic RNA (sgRNA) has been used to monitor active replication. Given the importance of long RT-PCR positivity and the need for work reincorporation and discontinuing isolation, we studied the functionality of normalized viral loads (NVL) for patient monitoring and sgRNA for viral infectivity detection. Read More

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Single image mixed dehazing method based on numerical iterative model and DehazeNet.

PLoS One 2021 30;16(7):e0254664. Epub 2021 Jul 30.

School of Computer Science and Technology, Shandong University of Finance and Economics, Jinan, China.

As one of the most common adverse weather phenomena, haze has caused detrimental effects on many computer vision systems. To eliminate the effect of haze, in the field of image processing, image dehazing has been studied intensively, and many advanced dehazing algorithms have been proposed. Physical model-based and deep learning-based methods are two competitive methods for single image dehazing, but it is still a challenging problem to achieve fidelity and effectively dehazing simultaneously in real hazy scenes. Read More

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Selection of stimulus parameters for enhancing slow wave sleep events with a neural-field theory thalamocortical model.

PLoS Comput Biol 2021 Jul 30;17(7):e1008758. Epub 2021 Jul 30.

Department of Electronic Engineering, Universidad Técnica Federico Santa María, Valparaíso, Chile.

Slow-wave sleep cortical brain activity, conformed by slow-oscillations and sleep spindles, plays a key role in memory consolidation. The increase of the power of the slow-wave events, obtained by auditory sensory stimulation, positively correlates to memory consolidation performance. However, little is known about the experimental protocol maximizing this effect, which could be induced by the power of slow-oscillation, the number of sleep spindles, or the timing of both events' co-occurrence. Read More

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Laser refrigeration of optically levitated sodium yttrium fluoride nanocrystals.

Opt Lett 2021 Aug;46(15):3797-3800

Solid state laser refrigeration can cool optically levitated nanocrystals in an optical dipole trap, allowing for internal temperature control by mitigating photothermal heating. This work demonstrates cooling of ytterbium-doped cubic sodium yttrium fluoride nanocrystals to 252 K on average with the most effective crystal cooling to 241 K. The amount of cooling increases linearly with the intensity of the cooling laser and is dependent on the pressure of the gas surrounding the nanocrystal. Read More

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Chrysanthemum flower like silica with highly dispersed Cu nanoparticles as a high-performance NO adsorbent.

J Hazard Mater 2021 Jun 12;418:126400. Epub 2021 Jun 12.

City University of Hong Kong Shenzhen Research Institute, Nanshan District, Shenzhen 518000, PR China; School of Energy and Environment, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China. Electronic address:

Atmospheric NO removal is urgent and necessary due to its negative effects on the eco-system. Here we developed the chrysanthemum flower-like silica (KCC-1) loaded with highly dispersed copper nanoparticles for efficient NO removal under ambient conditions. We carefully studied the NO removal performance of Cu-KCC-1 materials with different copper loadings (0, 5, 10, and 15 wt%) and demonstrated the Cu nanoparticles (10 wt%) boosted the NO removal capacity of KCC-1 by up to 51 times. Read More

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Impact of landscape pattern changes on hydrological ecosystem services in the Beressa watershed of the Blue Nile Basin in Ethiopia.

Sci Total Environ 2021 Jun 22;793:148559. Epub 2021 Jun 22.

Spatial Sciences Discipline, School of Earth and Planetary Sciences, Curtin University, Perth, Australia.

Landscape pattern changes are mostly due to human activities, and such changes often affect ecosystem functions and services. This study was conducted to evaluate the response of hydrological ecosystem services (HESs) to structural landscape changes. Spatiotemporal changes in two specific HES indicators, water yield (WY) and sediment export (SE), were quantified by analyzing historic (1972-2017) and projected land use/land cover changes (2017-2047). Read More

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