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The urban public realm and adolescent mental health and wellbeing: A systematic review.

Soc Sci Med 2021 Jul 20;284:114242. Epub 2021 Jul 20.

NHMRC Centre of Research Excellence in Healthy Housing, Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, 207 Bouverie Street, Parkville, Victoria, 3010, Australia. Electronic address:

Adolescent mental health is becoming a critical concern. Mental illness rates are rising and many psychological disorders first present symptoms during teenage years. Studies consistently show associations between the built environment and mental health, including internalising mental health disorders in adults, but the evidence for adolescents is less robust and few studies attempt to isolate causality. Read More

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COVID-19 Deliveries: Maternal Features and Neonatal Outcomes.

J Patient Cent Res Rev 2021 19;8(3):286-289. Epub 2021 Jul 19.

Aurora Cardiovascular and Thoracic Services, Aurora Sinai/Aurora St. Luke's Medical Centers, Milwaukee, WI; University of Wisconsin School of Medicine and Public Health, Madison, WI.

Integrated, data-driven criteria are necessary to evaluate delivery outcomes in pregnancies affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the ongoing COVID-19 pandemic. This study analyzed maternal demographics, clinical characteristics, treatments, and delivery outcomes of 85 ethnically diverse, adult pregnant women who tested positive for SARS-CoV-2 at the time of delivery. Median maternal and gestational ages were 27 years (interquartile range [IQR]: 23-31) and 39 weeks (IQR: 37. Read More

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Prognostic Factors and Predictors of In-Hospital Mortality Among COVID-19 Patients Admitted to the Intensive Care Unit: An Aid for Triage, Counseling, and Resource Allocation.

Cureus 2021 Jul 23;13(7):e16577. Epub 2021 Jul 23.

Department of Internal Medicine, Kuwait University, Health Sciences Center, School of Medicine, Kuwait, KWT.

Background:  The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains today a global health pandemic. Those with severe infection are at risk of rapid clinical deterioration; as a result, intensive care unit (ICU) admission is not uncommon in such patients. A number of determinants have been identified as predictors of poor prognosis and in-hospital mortality, ranging from demographic characteristics, laboratory and/or radiological findings. Read More

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Admission hyperglycemia is associated with reperfusion failure in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis.

Am J Cardiovasc Dis 2021 15;11(3):348-359. Epub 2021 Jun 15.

Division of Cardiovascular Medicine, Keck School of Medicine of University of Southern California Los Angeles, CA, USA.

Background: Admission hyperglycemia (AH) is a common finding in patients with acute coronary syndrome and has been reported to be associated with increased morbidity and mortality. Prior studies suggest that AH could be associated with reperfusion failure. We conducted a systematic review and meta-analysis to explore an association between AH and risk of reperfusion failure in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). Read More

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Effects of Facets of Mindfulness on College Adjustment Among First-Year Chinese College Students: The Mediating Role of Resilience.

Psychol Res Behav Manag 2021 22;14:1101-1109. Epub 2021 Jul 22.

JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, 999077, People's Republic of China.

Introduction: College life is a challenging stage for students to transition from adolescence to early adulthood. College students need to adjust to various problems, including those related to learning, campus life, interpersonal relationships, career selection, emotions, and self. The aim of this study was to test the associations between different facets of mindfulness, resilience, and college adjustment, as well as the mediation effect of resilience between mindfulness and college adjustment among first-year college students. Read More

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Performance of the Hull Salford Cambridge Decision Rule (HSC DR) for early discharge of patients with findings on CT scan of the brain: a CENTER-TBI validation study.

Emerg Med J 2021 Jul 27. Epub 2021 Jul 27.

Centre for Urgent and Emergency Care Research (CURE), School of Health and Related Research (ScHARR). Emergency Department, Salford Royal Hospital, University of Sheffield and Salford Royal Hospital, Sheffield, UK.

Background: There is international variation in hospital admission practices for patients with mild traumatic brain injury (TBI) and injuries on CT scan. Only a small proportion of patients require neurosurgical intervention, while many guidelines recommend routine admission of all patients. We aim to validate the Hull Salford Cambridge Decision Rule (HSC DR) and the Brain Injury Guidelines (BIG) criteria to select low-risk patients for discharge from the emergency department. Read More

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Order Set Use and Education Association With Pediatric Acute Pancreatitis Outcomes.

Hosp Pediatr 2021 Aug;11(8):885-892

Children's Healthcare of Atlanta and Division of Gastroenterology, Hepatology and Nutrition

Background: The management of acute pancreatitis (AP) in children was historically derived from adult practice recommendations. Pediatric-specific recommendations for treatment of AP were recently developed by North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, but their impact on clinical outcomes has yet to be evaluated. We developed an AP order set on the basis of these recommendations to assess impact on clinical outcomes. Read More

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Implant sonication versus intraoperative tissue sample cultures for Periprosthetic Joint Infection (PJI) of Shoulder Arthroplasty.

Acta Biomed 2021 07 26;92(S3):e2021009. Epub 2021 Jul 26.


Introduction Periprosthetic joint infection (PJI) is the most problematic complications after shoulder arthroplasty. Many diagnostic tools have been identified to find infection, such as hystopatologic examination of tissue sections or cultures of intraoperative tissue. Implant sonication fluid culture showed good results in order to enhance diagnostic accuracy, but literature results are still controversial. Read More

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Support needs of parents in neonatal intensive care unit: An integrative review.

J Clin Nurs 2021 Jul 26. Epub 2021 Jul 26.

School of Nursing and Midwifery, Edith Cowan University, Perth, Western Australia, Australia.

Background: Having an infant in the neonatal intensive care unit (NICU) is associated with intense emotional stress for both mothers and fathers. However, with the right support from staff, this stress can be reduced significantly. Although evidence on needs of parents in the neonatal unit exists, there is lack of a systematic integrative review on the support needs of parents in the neonatal unit. Read More

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Status, demand and practice models of palliative day-care clinics and day hospices: a scoping review.

BMJ Support Palliat Care 2021 Jul 26. Epub 2021 Jul 26.

Institute for General Practice and Palliative Care, Hannover Medical School, Hannover, Germany

Background: Little is known about the structure, accessibility, service provision and needs of palliative and hospice day-care in Germany and abroad. Researchers, healthcare providers and policy makers would benefit from a systematic overview.

Aim: The aim was to identify, describe and summarise available evidence on status, demand and practice models of palliative day-care clinics and day hospices. Read More

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Nursing Program Admission Barriers in the United States: Considerations for Increasing Black Student Enrollment.

Nurse Educ 2021 Jul 19. Epub 2021 Jul 19.

Author Affiliations: Associate Professor (Dr Hampton), Assistant Professor (Drs Dawkins and Rickman Patrick), Director and Professor (Dr O'Leary-Kelley), and Nursing Students (Ms Onglengco and Ms Stobbe), The Valley Foundation School of Nursing, San Jose State University, California.

Background: The percentage of Black registered nurses (RN) is disproportionate to Black residents in the population, particularly in Southern states.

Purpose: This study's purpose was to identify the potential admission barriers for Black students in RN education in the South versus Midwest, Northeast, and West.

Methods: A cross-sectional design was used to compare admission criteria for 1597 accredited associate degree in nursing and bachelor of science in nursing programs by geographic region. Read More

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Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.

JAMA Netw Open 2021 Jul 1;4(7):e2116839. Epub 2021 Jul 1.

Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

Importance: Intracerebral hemorrhage progression is associated with unfavorable outcome after traumatic brain injury (TBI). No effective treatments are currently available. This secondary injury process reflects an extreme form of vasogenic edema and blood-brain barrier breakdown. Read More

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A Machine Learning-Based Algorithm for the Prediction of Intensive Care Unit Delirium (PRIDE): Retrospective Study.

JMIR Med Inform 2021 Jul 26;9(7):e23401. Epub 2021 Jul 26.

Department of Critical Care Medicine and Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: Delirium frequently occurs among patients admitted to the intensive care unit (ICU). There is limited evidence to support interventions to treat or resolve delirium in patients who have already developed delirium. Therefore, the early recognition and prevention of delirium are important in the management of critically ill patients. Read More

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Barriers to recruitment, retention and intervention delivery in a randomized trial among patients with firearm injuries.

Inj Epidemiol 2021 Jul 26;8(1):37. Epub 2021 Jul 26.

Firearm Injury & Policy Research Program, Harborview Injury Prevention & Research Center, University of Washington, Seattle, WA, USA.

Background: We discuss barriers to recruitment, retention, and intervention delivery in a randomized controlled trial (RCT) of patients presenting with firearm injuries to a Level 1 trauma center. The intervention was adapted from the Critical Time Intervention and included a six-month period of support in the community after hospital discharge to address recovery goals. This study was one of the first RCTs of a hospital- and community-based intervention provided solely among patients with firearm injuries. Read More

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COVID-19 and invasive fungal coinfections: A case series at a Brazilian referral hospital.

J Mycol Med 2021 Jul 14;31(4):101175. Epub 2021 Jul 14.

School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil. Electronic address:

Background: COVID-19 co-infections have been described with different pathogens, including filamentous and yeast fungi.

Methodology: A retrospective case series study conducted from February to December 2020, at a Brazilian university hospital. Data were collected from two hospital surveillance systems: Invasive fungal infection (IFI) surveillance (Mycosis Resistance Program - MIRE) and COVID-19 surveillance. Read More

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Maternal height, gestational diabetes mellitus and pregnancy complications.

Diabetes Res Clin Pract 2021 Jul 23;178:108978. Epub 2021 Jul 23.

Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore; Department of Obstetrics and Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

Aims: To explore the glucose-overload hypothesis of artefactual gestational diabetes (GDM) diagnosis in shorter women during oral glucose tolerance testing (OGTT), by investigating associations between height and maternal glycemia; and GDM and pregnancy complications in height-groups.

Methods: Women from GUSTO (n = 1100, 2009-2010) and NUH (n = 4068, 2017-2018) cohorts underwent a mid-gestation two and three time-point 75 g 2-hour OGTT, respectively. GDM-related complications (hypertensive disorders of pregnancy, preterm delivery, emergency cesarean section, neonatal intensive care unit admission, macrosomia, birthweight) were compared within shorter and taller groups, dichotomized by ethnic-specific median height. Read More

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Early Palliative Care Consultation in the Burn Unit: A Quality Improvement Initiative to Increase Utilization.

J Burn Care Res 2021 Jul 24. Epub 2021 Jul 24.

Department of Surgery, University of Colorado School of Medicine.

Despite significant morbidity and mortality for major burns, palliative care consultation (PCC) is underutilized in this population. The purpose of this study is to examine the impact of a protocol using recommended "triggers" for PCC at a single academic burn center. This is a retrospective review of patient deaths over a four-year period. Read More

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Appropriateness of inpatient dosing of direct oral anticoagulants for atrial fibrillation.

J Thromb Thrombolysis 2021 Jul 24. Epub 2021 Jul 24.

Department of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, 5000, Australia.

Direct oral anticoagulant (DOAC) use for stroke prevention in atrial fibrillation (AF) has dose reduction criteria including age, weight, serum creatinine, and creatinine clearance. There is a paucity of data for rates of inappropriate inpatient DOAC dosing in Australia. The objective was to determine the rates of inappropriate inpatient DOAC dosing in AF and identifying its associated underlying factors. Read More

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Developing a pulse oximetry home monitoring protocol for patients suspected with COVID-19 after emergency department discharge.

BMJ Health Care Inform 2021 Jul;28(1)

Harvard Medical School, Boston, Massachusetts, USA.

Objectives: Patients with COVID-19 can present to the emergency department (ED) without immediate indication for admission, but with concern for decompensation. Clinical experience has demonstrated that critical illness may present later in the disease course and hypoxia is often the first indication of disease progression. The objectives of this study are to (a) assess feasibility and describe a protocol for ED-based outpatient pulse-oximetry monitoring with structured follow-up and (b) determine rates of ED return, hospitalisation and hypoxia among participants. Read More

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Moving Towards FAIR Data Practices in Pharmacy Education.

Am J Pharm Educ 2021 Jul 22:8670. Epub 2021 Jul 22.

University of North Carolina, Eshelman School of Pharmacy, Chapel Hill, North Carolina.

Pharmacy schools are generating significant amounts of data across the training continuum, including data about student selection, performance, and job placement. However, current data practices limit our ability to effectively leverage the vast amounts of data available within and across our institutions. In an effort to improve data practices and promote the quality and reusability of data, the FAIR guiding principles for data management and stewardship were developed and published in 2016. Read More

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Increased Mortality in Elderly Patients Admitted with Hyponatremia: A Prospective Cohort Study.

J Clin Med 2021 Jul 10;10(14). Epub 2021 Jul 10.

Department of Internal Medicine, University Hospital of Heraklion, 71110 Heraklion, Greece.

Hyponatremia is the most common electrolyte disorder, commonly affecting older hospitalized individuals; however, the literature is not clear regarding its effect on mortality. The aim of this 2-year observational prospective cohort study was to evaluate the mortality and re-admission rates, the clinical and laboratory characteristics and the causes of hyponatremia in patients older than 65 years admitted with a corrected serum sodium of 130 mEq/L or less in an internal medicine ward of a tertiary Greek university hospital. During the observation period, 138 patients (mean age 80. Read More

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Early Prediction of Student Learning Performance Through Data Mining: A Systematic Review.

Psicothema 2021 Aug;33(3):456-465

Escuela Superior Politécnica Agropecuaria de Manabí.

Background: Early prediction of students’ learning performance using data mining techniques is an important topic these days. The purpose of this literature review is to provide an overview of the current state of research in that area.

Method: We conducted a literature review following a two-step procedure, looking for papers using the major search engines and selection based on certain criteria. Read More

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Pre-graduation grade inflation in medical training in Turkey: a longitudinal study from 2005 to 2020.

Engin Karadag

BMC Med Educ 2021 Jul 22;21(1):395. Epub 2021 Jul 22.

Akdeniz University, Campus, 07070, Antalya, Turkey.

Background: Grade inflation which is known as the awarding of higher grades than students deserve in higher education has been observed since the 1960s. There is comprehensive evidence that document the allegations, prevalence, and severity of grade inflation in higher education in universities around the world for the past 10 years.

Methods: This study analyzes the change in the ratio of graduates with a "very good (>2. Read More

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Expectations of and for Clerkship Directors 2.0: A Collaborative Statement from the Alliance for Clinical Education.

Teach Learn Med 2021 Jul 23:1-12. Epub 2021 Jul 23.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

This article presents an update of the collaborative statement on clerkship directors (CDs), first published in 2003, from the national undergraduate medical education organizations that comprise the Alliance for Clinical Education (ACE). The clerkship director remains an essential leader in the education of medical students on core clinical rotations, and the role of the CD has and continues to evolve. The selection of a CD should be an explicit contract between the CD, their department, and the medical school, with each party fulfilling their obligations to ensure the success of the students, the clerkship and of the CD. Read More

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Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis.

Front Med (Lausanne) 2021 5;8:699412. Epub 2021 Jul 5.

Faculty of Nursing and Health Sciences, Nord University, Bodø, Norway.

Mild gestational diabetes (GDM) refers to the gestational hyperglycemia, which does not fulfill the diagnostic criteria for GDM. The results of studies on adverse pregnancy outcomes among women with mild GDM are controversial. Therefore, the aim of this systematic review and meta-analysis was to investigate the impact of mild GDM on the risk of adverse maternal and neonatal outcomes. Read More

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Violent Behavior Prior to Admission Is Not a Factor in Further Prolonged Length of Stay: A Retrospective Cohort Study in a Japanese Psychiatric Hospital.

Front Psychiatry 2021 5;12:600456. Epub 2021 Jul 5.

Forensic Mental Health Unit, Department of Psychiatry and Behavioral Sciences, Division of Cognitive and Behavioral Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

This study assessed the hypothesis that violent behavior prior to admission prolongs psychiatric hospitalization and evaluated the likelihood of hospital discharge to a community care setting based on demographic and clinical factors, with an emphasis on violent behavior. We retrospectively selected 362 patients who were involuntarily admitted to a psychiatric hospital in Japan from December 1, 2015 to November 30, 2017, stayed longer than planned, and underwent review by a multidisciplinary team. We assessed (a) education and marital status and history of substance abuse, (b) the presence/absence and type of violent behavior that led to hospital admission, and (c) the discharge criteria. Read More

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Impact of Student-Run Clinics on Students' Attitudes Toward People Experiencing Homelessness.

PRiMER 2021 18;5:19. Epub 2021 Jun 18.

Department of Family and Community Medicine, Temple University Health System, Philadelphia, PA.

Introduction: Student-run clinics can supplement medical education by exposing students to diverse clinical scenarios and collaborating with underresourced populations. We examined the impact of volunteering at THRIVE, a student-run bridge clinic located within sheltered housing for individuals with substance use disorder, on students' attitudes toward people experiencing homelessness (PEH).

Methods: This cohort study analyzed pre- and postsurvey matched responses from nonvolunteer and volunteer first-year medical students utilizing the Health Professional Attitudes Towards the Homeless (HPATHI) tool, totaled into three subcategories: Cynicism, Social Advocacy, and Personal Advocacy. Read More

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All We Can Be: Innovations to Improve the Pipeline of Military Veterans in Medical Schools.

Teach Learn Med 2021 Jul 21:1-8. Epub 2021 Jul 21.

Department of Medical Education, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Issue: Medical schools are increasingly identifying military veteran applicants as a source of diversity, resiliency, and commitment-often derived from their personal experiences in the military. Yet, veterans remain significantly under-represented in entering classes; moreover, those veterans who do matriculate are not yet fully reflective of the diversity that the Armed Forces have to offer. Fortunately, specific measures have been shown to be effective at increasing both the number and diversity of student veterans in medical school. Read More

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Simulated Wound Care as a Competence Assessment Method for Student and Registered Nurses.

Adv Skin Wound Care 2021 Jul 19. Epub 2021 Jul 19.

At the University of Turku, Finland, Emilia Kielo-Viljamaa, MNSc, RN, is a PhD Candidate; Maarit Ahtiala, RN, is a wound care nurse; Riitta Suhonen, PhD, RN, is Professor and Director of Nursing; and Minna Stolt, PhD, is Lecturer. Acknowledgments: The authors thank the study participants as well as the wound care experts who gave their best efforts and assistance to develop the study instrument. They also thank the Finnish Wound Care Society and the University of Turku for financial support, as well as Mölnlycke Health Care AB for sponsoring some of the wound care products used in the simulations. The authors have disclosed no other financial relationships related to this article. Submitted November 3, 2020; accepted in revised form January 8, 2021.

Objective: To describe the development and use of a wound care simulation assessing registered nurses' and graduating student nurses' practical wound care competence, and to describe observations of participants' wound care competence.

Methods: A descriptive, qualitative design was used. Data were collected in 2019 from 50 health care professionals and students using a simulated wound care situation and an imaginary patient case. Read More

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A Mapping Review of Teamwork Training and Assessment in Pharmacy Education.

Am J Pharm Educ 2021 Mar 23;85(3):8356. Epub 2020 Dec 23.

University of North Carolina at Chapel Hill, UNC Eshelman School of Pharmacy, Chapel Hill, North Carolina.

To explore how teamwork is taught (ie, skills and format), measured, and assessed within pharmacy education. A mapping review was conducted to provide a selection of articles to specifically capture how teamwork is taught, measured, and assessed within pharmacy education. Of the 114 references retrieved, 18 studies from 17 schools or colleges of pharmacy met the inclusion criteria for review and data abstraction. Read More

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