116,510 results match your criteria stroke risk

Re-operative aortic arch surgery in a contemporary series.

Semin Thorac Cardiovasc Surg 2021 May 7. Epub 2021 May 7.

Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA. Electronic address:

Re-operative aortic arch operations (REDO) following previous cardiac surgery are challenging procedures associated with significant morbidity and mortality. We investigated post-operative outcomes for patients undergoing REDO and identified risk-factors for mortality in a contemporary series. From 1/2005-6/2018, 365 consecutive patients at an academic center underwent REDO: 257 HEMIARCH and 108 COMPLETE arch (45 stage I elephant trunk, 63 total arch) replacements. Read More

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Sex Differences in Ascending Aortic and Arch Surgery: A Propensity-matched Comparison of 1153 Pairs.

Ann Thorac Surg 2021 May 7. Epub 2021 May 7.

Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine; Section of Adult Cardiac Surgery, Department of Cardiovascular Surgery, Texas Heart Institute; Department of Cardiovascular Surgery, CHI St Luke's Health-Baylor St Luke's Medical Center; Cardiovascular Research Institute, Baylor College of Medicine, Houston, Texas.

Background: We investigated the relationship of sex with clinical outcomes after proximal aortic (ascending and arch) operations, and whether sex-specific preoperative factors are associated with mortality.

Methods: Of 3745 patients who underwent elective, urgent, and emergency proximal aortic operations over a 20-year period, 1153 pairs of men and women were propensity-matched, and their early and long-term outcomes were compared. Kaplan-Meier survival analysis was used to estimate late survival. Read More

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Transcranial color-coded duplex sonography reliably identifies intracranial vasculopathy in adults patients with sickle cell disease.

Am J Hematol 2021 May 10. Epub 2021 May 10.

INSERM 1266 Institut de Psychiatrie et Neurosciences de ParisDHU Neurovasc - Paris Sorbonne, Paris, France.

In order to prevent stroke, screening for disease-related intracranial vasculopathy using Doppler is recommended in sickle-cell disease (SCD) children. How to screen such vasculopathy in adults remains largely unknown. The objective of this study was to assess whether Transcranial color-coded duplex sonography (TCCD) is sensitive and specific to identify SCD adult patients with vasculopathy, compared with magnetic resonance angiography (MRA). Read More

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Peak atrial longitudinal strain is predictive of atrial fibrillation in patients with chronic obstructive pulmonary disease and coronary artery disease.

Echocardiography 2021 May 10. Epub 2021 May 10.

UO Cardiologia, Azienda Ospedaliero Universitaria di Ferrara, Ferrara, Italy.

Background: The peak atrial longitudinal strain (PALS) has been validated in the prediction of atrial fibrillation (AF) in the general population. If this finding can be applied to patients with chronic obstructive pulmonary disease (COPD) and concomitant coronary artery disease (CAD) is unknown.

Methods And Results: We analyzed two different study populations of patients with COPD and acute CAD in SCAP trial (Clinical trial. Read More

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Treatments for unruptured intracranial aneurysms.

Cochrane Database Syst Rev 2021 May 10;5:CD013312. Epub 2021 May 10.

Department of Surgery, Division of Vascular and Endovascular Surgery, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Unruptured intracranial aneurysms are relatively common lesions in the general population, with a prevalence of 3.2%, and are being diagnosed with greater frequency as non-invasive techniques for imaging of intracranial vessels have become increasingly available and used. If not treated, an intracranial aneurysm can be catastrophic. Read More

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Temporal Trends in Case Fatality, Discharge Destination, and Admission to Long-term Care After Acute Stroke.

Neurology 2021 Apr 23;96(16):e2037-e2047. Epub 2021 Mar 23.

From the Department of Clinical Neurosciences (R.A.J., E.E.S.), Cumming School of Medicine, University of Calgary; ICES (R.A.J., A.Y.X.Y., M.R., J.F., M.K.K.), Toronto; and the Department of Medicine, Divisions of Neurology (A.Y.X.Y.) and General Internal Medicine (M.K.K.), and Institute of Health Policy, Management, and Evaluation (M.K.K.), University of Toronto, Canada.

Objective: To determine contemporary trends in case fatality, discharge destination, and admission to long-term care after acute ischemic stroke and intracerebral hemorrhage (ICH) using a large, population-based cohort.

Methods: We used linked administrative data to identify all emergency department visits and hospital admissions for first-ever ischemic stroke or ICH in Ontario, Canada, from 2003 to 2017. We calculated crude and age-/sex-standardized risk of death at 30 days and 1 year from stroke onset. Read More

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Caracole as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic.

CNS Neurol Disord Drug Targets 2021 May 6. Epub 2021 May 6.

Department of Family Medicine, Ali-Ibn Abi-Talib Hospital, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan,Iran.

Background & Objective: Neurological diseases are becoming a significant problem worldwide, with the elderly at a higher risk of being affected. Several researchers have investigated the neuroprotective effects of Carvacrol (CAR) (5-isopropyl-2-methyl phenol). This review systematically surveys the existing literature on the impact of CAR when used as a neuroprotective agent in neurological diseases. Read More

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Assessment of Recurrent Stroke Risk in Patients With a Carotid Web.

JAMA Neurol 2021 May 10. Epub 2021 May 10.

Department of Neurology, Amsterdam UMC, University of Amsterdam, Neurology, Amsterdam, the Netherlands.

Importance: A carotid web (CW) is a shelf-like lesion along the posterior wall of the internal carotid artery bulb and an underrecognized cause of young stroke. Several studies suggest that patients with symptomatic CW have a high risk of recurrent stroke, but high-quality data are lacking.

Objective: To assess the 2-year risk of recurrent stroke in patients with a symptomatic CW. Read More

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Atrial thrombus detection on transoesophageal echocardiography in patients with atrial fibrillation undergoing cardioversion or catheter ablation: A pooled analysis of rates and predictors.

J Cardiovasc Electrophysiol 2021 May 9. Epub 2021 May 9.

Non-Communicable Diseases Research Unit, South African Medical Research Council, Durban and Cape Town, South Africa.

Objective: To summarize data on the rates and predictors of left atrial/left atrial appendage thrombus (LAT/LAAT) detection by transoesophageal echocardiography (TEE) prior to electrical cardioversion (ECV) or catheter ablation (CA) for atrial fibrillation (AF).

Methods: EMBASE, MEDLINE, and Web of Science were searched to identify all studies providing relevant data and published by October 07, 2020. Random-effects meta-analysis method was used to pool estimates. Read More

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Fine-Gray subdistribution hazard models to simultaneously estimate the absolute risk of different event types: Cumulative total failure probability may exceed 1.

Stat Med 2021 May 9. Epub 2021 May 9.

Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands.

The Fine-Gray subdistribution hazard model has become the default method to estimate the incidence of outcomes over time in the presence of competing risks. This model is attractive because it directly relates covariates to the cumulative incidence function (CIF) of the event of interest. An alternative is to combine the different cause-specific hazard functions to obtain the different CIFs. Read More

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Predictors of motor outcome after childhood arterial ischemic stroke.

Dev Med Child Neurol 2021 May 9. Epub 2021 May 9.

UCL Great Ormond Street Institute of Child Health, London, UK.

Aim: To identify clinical and radiological predictors of long-term motor outcome after childhood-onset arterial ischemic stroke (AIS) in the middle cerebral artery (MCA) territory.

Method: Medical records of 69 children (36 females, 33 males; median age at index AIS 3y 3mo, range: 1mo-16y) who presented to Great Ormond Street Hospital with first AIS in the MCA territory were reviewed retrospectively. Cases were categorized using the Childhood AIS Standardized Classification and Diagnostic Evaluation (CASCADE). Read More

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Stroke risk prediction using machine learning: a prospective cohort study of 0.5 million Chinese adults.

J Am Med Inform Assoc 2021 May 9. Epub 2021 May 9.

Department of Engineering Science, University of Oxford, Oxford, UK.

Objective: To compare Cox models, machine learning (ML), and ensemble models combining both approaches, for prediction of stroke risk in a prospective study of Chinese adults.

Materials And Methods: We evaluated models for stroke risk at varying intervals of follow-up (<9 years, 0-3 years, 3-6 years, 6-9 years) in 503 842 adults without prior history of stroke recruited from 10 areas in China in 2004-2008. Inputs included sociodemographic factors, diet, medical history, physical activity, and physical measurements. Read More

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The COVID-19 Pandemic Sacrificed the Excellence of Stroke Care Worldwide.

SN Compr Clin Med 2021 May 3:1-3. Epub 2021 May 3.

Department of Neurology, Faculty of Medical Sciences of Santa Casa de São Paulo, Dr. Cesário Motta Júnior Street 112, São Paulo, 01221-020 Brazil.

The COVID-19 pandemic has had not only a tremendous impact on public health but also on the care of many pre-COVID-19 diseases, such as stroke. The pandemic has tested the robustness of comprehensive stroke care programs. Especially during the months of confinement, an alarming increase in the incidence of several risk factors for cerebrovascular diseases was noticed, without, however, the proportional strengthening of strategies for the prevention and/or control of comorbidities. Read More

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Association of the Ratio of Triglycerides to High-Density Lipoprotein Cholesterol Levels with the Risk of Type 2 Diabetes: A Retrospective Cohort Study in Beijing.

J Diabetes Res 2021 20;2021:5524728. Epub 2021 Apr 20.

The Department and Key Laboratory of Endocrinology and Metabolism, The First Medical Center of PLA General Hospital, Beijing 100853, China.

Background: Previous studies have shown that the ratio of triglyceride to high-density lipoprotein cholesterol level (TG/HDL-C) is a risk factor for type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the nonlinear relationship between TG/HDL-C and the incidence of T2DM in a Chinese population.

Methods: We used logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the incidence of T2DM among 7,791 participants from the Risk Evaluation of cAncers in Chinese diabeTic Individuals: a lONgitudinal (REACTION) cohort study at baseline. Read More

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Perioperative massive cerebral stroke in thoracic patients: Report of three cases.

World J Clin Cases 2021 May;9(13):3170-3176

Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.

Background: Perioperative stroke is a rare but devastating complication. The risk factors for massive cerebral stroke in surgical patients include older age, male sex, prior cerebrovascular disease, hypertension, renal failure, smoking, diabetes mellitus, and atrial fibrillation.

Case Summary: We describe two cases of perioperative massive cerebral stroke following thoracic surgery and one case following bronchoscopy. Read More

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Intramuscular hematoma in rhabdomyolysis patients treated with low-molecular-weight heparin: Report of two cases.

World J Clin Cases 2021 Apr;9(12):2838-2844

Department of Critical Care Medicine, Nanping First Hospital Affiliated to Fujian Medical University, Nanping 353000, Fujian Province, China.

Background: Rhabdomyolysis is a serious complication of heat stroke. Unlike that in acute kidney injury, the risk of muscle bleeding in rhabdomyolysis is often ignored and can substantially increase the widespread use of anticoagulants, leading to the formation of intramuscular hematoma.

Case Summary: During the summer, a middle-aged man and an elderly man were diagnosed with heat stroke, rhabdomyolysis, and acute renal impairment. Read More

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Association Between Epicardial Adipose Tissue and Stroke.

Front Cardiovasc Med 2021 21;8:658445. Epub 2021 Apr 21.

Department of Clinical Research, Federal University of Uberlândia, Uberlândia, Brazil.

Epicardial adipose tissue (EAT) is correlated with endothelial dysfunction, metabolic syndrome, increased mortality and recent studies showed a possible association with the increased risk of stroke. We performed a systematic review of studies evaluating the association between EAT and stroke. Eighty studies met the inclusion criteria and were consequently analyzed. Read More

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Acute hemorrhagic cholecystitis with gallbladder rupture and massive intra-abdominal hemorrhage.

Autops Case Rep 2021 Jan 28;11:e2020232. Epub 2021 Jan 28.

University of Michigan, Michigan Medicine, Department of Surgery, Ann Arbor, Michigan, USA.

Acute hemorrhagic cholecystitis is a rare, life-threatening condition that can be further complicated by perforation of the gallbladder. We describe a patient with clinical and radiologic findings of acute cholecystitis with a gallbladder rupture and massive intra-abdominal bleeding. Our patient is a 67-year-old male who presented with an ischemic stroke and was treated with early tissue plasminogen activator. Read More

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January 2021

Narrative review on Morbus Fabry: diagnosis and management of cardiac manifestations.

Cardiovasc Diagn Ther 2021 Apr;11(2):650-660

2nd Department of Internal Cardiovascular Medicine, General University Hospital, Prague, Czech Republic.

Fabry disease (FD) is an X-linked lysosomal storage disorder due to reduced or undetectable α-galactosidase A (AGAL-A) enzyme activity caused by pathogenic variants in the AGAL-A gene (). Tissue and organ changes are caused by widespread progressive accumulation of globotriaosylceramide (Gb) and globotriaosylsphingosine (lysoGb). The classical form of FD is multisystemic with cutaneous (angiokeratomas), neurological (peripheral neuropathy, premature stroke), renal (proteinuria and renal insufficiency), and cardiac involvement. Read More

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Therapy of supraventricular and ventricular arrhythmias in adults with congenital heart disease-narrative review.

Cardiovasc Diagn Ther 2021 Apr;11(2):550-562

Department of Cardiology II - Electrophysiology, University Hospital Muenster, Cardiology, Muenster, Germany.

Arrhythmias are among the most common late complications in adults with congenital heart disease (ACHD) and a frequent reason for hospital admission. Both, supraventricular and ventricular arrhythmias, not only cause debilitating symptoms, but may be life-threatening by increasing risk of stroke, causing or worsening heart failure and being associated with sudden death. Substrate and risk for arrhythmia differs widely between congenital defects with specific arrhythmias being much more common in some patients than others. Read More

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Challenges in managing ST elevation myocardial infarction during the COVID-19 pandemic.

World J Cardiol 2021 Apr;13(4):76-81

Department ofCardiology, University of Kentucky College of Medicine, Bowling Green, KY 42101, United States.

Background: Coronavirus disease 2019 (COVID-19) may contribute to delayed presentations of acute myocardial infarction. Delayed presentation with late reperfusion is often associated with an increased risk of mechanical complications and adverse outcomes. Inherent delays are possible as every patient who is acutely sick is being considered a potential case or a career of COVID-19. Read More

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Life-threatening complications of hyperemesis gravidarum.

Exp Ther Med 2021 Jun 16;21(6):642. Epub 2021 Apr 16.

Department of Neurology, 'Iuliu Hatieganu' University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca 400012, Romania.

Hyperemesis gravidarum (HG) refers to severe nausea and emesis noted during pregnancy. However, no consensus exists on the specific diagnostic criteria that can be used for this condition. The aim of the present systematic review was to summarize the available evidence regarding the severe complications observed during HG with a heightened risk of fatality. Read More

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The Incidence of Stroke in Indigenous Populations of Countries With a Very High Human Development Index: A Systematic Review Protocol.

Front Neurol 2021 22;12:661570. Epub 2021 Apr 22.

School of Population and Global Health, University of Western Australia, Perth, WA, Australia.

Despite known Indigenous health and socioeconomic disadvantage in countries with a Very High Human Development Index, data on the incidence of stroke in these populations are sparse. With oversight from an Indigenous Advisory Board, we will undertake a systematic review of the incidence of stroke in Indigenous populations of developed countries or regions, with comparisons between Indigenous and non-Indigenous populations of the same region, though not between different Indigenous populations. Using PubMed, OVID-EMBASE, and Global Health databases, we will examine population-based incidence studies of stroke in Indigenous adult populations of developed countries published 1990-current, without language restriction. Read More

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Outcomes of Ischemic Stroke and Associated Factors Among Elderly Patients With Large-Artery Atherosclerosis: A Hospital-Based Follow-Up Study in China.

Front Neurol 2021 23;12:642426. Epub 2021 Apr 23.

Department of Rehabilitation Medicine, Dongying People's Hospital, Dongying, China.

Large-artery atherosclerotic (LAA) stroke is the most common subtype of ischemic stroke. However, risk factors for long-term outcomes of LAA stroke in the elderly Chinese population have not been well-described. Therefore, we aimed to assess outcomes and risk factors at 3, 12, and 36 months after LAA stroke onset among stroke patients aged 60 years and older. Read More

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Disease Status-Dependent Drug-Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and J. Ellis.

Front Pharmacol 2021 23;12:622040. Epub 2021 Apr 23.

School of Pharmacy, The Chinese University of Hong Kong, Shatin, Hong Kong.

Concurrent use of simvastatin (SV) and J. Ellis (GJ) was adopted in patients with multi-morbidity, such as stroke rehabilitation patients with NASH. Although hepatotoxicity has been reported in both of them and NASH could alter the pharmacokinetics of drugs/herbs, the interaction between SV and GJ and the related hepatotoxicity remained uninvestigated under neither healthy nor NASH condition. Read More

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Nomogram to Predict Cognitive Dysfunction After a Minor Ischemic Stroke in Hospitalized-Population.

Front Aging Neurosci 2021 14;13:637363. Epub 2021 Apr 14.

Department of Neurology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.

An easily scoring system to predict the risk of cognitive impairment after minor ischemic stroke has not been available. We aimed to develop and externally validate a nomogram for predicting the probability of post-stroke cognitive impairment (PSCI) among hospitalized population with minor stroke. Moreover, the association of Trimethylamine N-oxide (TMAO) with PSCI is also investigated. Read More

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Association between rs1761667 CD36 polymorphism and risk of stroke in Korean patients with type 2 diabetes.

Chin Med J (Engl) 2021 May 6. Epub 2021 May 6.

Department of Internal Medicine, Chungbuk National University College of Medicine and Chungbuk National University Hospital, Cheongju, Republic of Korea Department of Biochemistry, Chungbuk National University College of Medicine, Cheongju, Republic of Korea Hanmi Internal Medicine Clinic, Cheongju, Republic of Korea.

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The Interrelation Between Chronic Headache, Cognitive Scores, and MRI Markers Among Stroke Survivors.

J Alzheimers Dis 2021 May 4. Epub 2021 May 4.

Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

Background: Migraine is known to mildly increase the risk for ischemic stroke and is associated with vascular MRI markers. However, the potential effect of chronic headache (CH) on stroke outcomes has not been studied.

Objective: We aimed to assess the interrelation between CH and post-stroke cognitive impairment. Read More

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Urban Air Pollution Nanoparticles from Los Angeles: Recently Decreased Neurotoxicity.

J Alzheimers Dis 2021 May 4. Epub 2021 May 4.

Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.

Background: Air pollution is widely associated with accelerated cognitive decline at later ages and risk of Alzheimer's disease (AD). Correspondingly, rodent models demonstrate the neurotoxicity of ambient air pollution and its components. Our studies with nano-sized particulate matter (nPM) from urban Los Angeles collected since 2009 have shown pro-amyloidogenic and pro-inflammatory responses. Read More

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[Relationship between Stress Hyperglycemia and Catheter-related Urinary Tract Infection in Stroke Patients].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Apr;43(2):188-192

Department of Neurology,The Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou 558000,China.

Objective To verify the relationship between catheter-related urinary tract infection(CAUTI)and stress hyperglycemia during catheter retention in stroke patients. Methods We used nosocomial infection monitoring system to track the status of CAUTI in stroke patients in a hospital.The study cohort was all the patients who received retention catheterization from January 2016 to March 2020. Read More

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