38,774 results match your criteria strength investigated

25-hydroxycholesterol interacts differently with lipids of the inner and outer membrane leaflet - The Langmuir monolayer study complemented with theoretical calculations.

J Steroid Biochem Mol Biol 2021 May 10:105909. Epub 2021 May 10.

Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Kraków, Poland.

25-hydroxycholesterol (25-OH), a molecule with unusual behavior at the air/water interface, being anchored to the water surface alternatively with a hydroxyl group at C(3) or C(25), has been investigated in mixtures with main membrane phospholipids (phosphatidylcholines - PCs, and phosphatidylethanolamines - PEs), characteristic of the outer and inner membrane leaflet, respectively. To achieve this goal, the classical Langmuir monolayer approach based on thermodynamic analysis of interactions was conducted in addition to microscopic imaging of films (in situ with BAM and after transfer onto mica with AFM), surface-sensitive spectroscopy (PM-IRRAS), as well as theoretical calculations. Our results show that the strength of interactions is primarily determined by the kind of polar group (strong, attractive interactions leading to surface complexes formation were found to occur with PCs while weak or repulsive ones with PEs). Read More

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A two-step, test-guided Mokken scale analysis, for nonclustered and clustered data.

Qual Life Res 2021 May 13. Epub 2021 May 13.

Research Institute of Child Development and Education, University of Amsterdam, P. O. Box 15776, 1001 NG, Amsterdam, The Netherlands.

Purpose: Mokken scale analysis (MSA) is an attractive scaling procedure for ordinal data. MSA is frequently used in health-related quality of life research. Two of MSA's prime features are the scalability coefficients and the automated item selection procedure (AISP). Read More

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Parametric-based feature selection via spherical harmonic coefficients for the left ventricle myocardial infarction screening.

Med Biol Eng Comput 2021 May 13. Epub 2021 May 13.

Department of Biomedical Engineering and Medical Physics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Computer-aided diagnosis (CAD) of heart diseases using machine learning techniques has recently received much attention. In this study, we present a novel parametric-based feature selection method using the three-dimensional spherical harmonic (SHs) shape descriptors of the left ventricle (LV) for intelligent myocardial infarction (MI) classification. The main hypothesis is that the SH coefficients of the parameterized endocardial shapes in MI patients are recognizable and distinguishable from healthy subjects. Read More

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Ballistic performance of Polycarbonate and Polymethyl methacrylate under normal and inclined dynamic impacts.

Heliyon 2021 Apr 21;7(4):e06856. Epub 2021 Apr 21.

Anglia Ruskin University, Engineering and the Built Environment, CM1 1SQ, Chelmsford, Essex, United Kingdom.

Polymeric materials have exceptional mechanical properties, making them attractive for automotive, aerospace, defence and buildings industries. The numerical analysis of translucent polymeric materials' ballistic performance is investigated to analyse the deflection and perforation performance at high impact velocities. Computational methods are exploited to predict the ballistic performance of thick targets and projectile damage, and the results are validated against published works. Read More

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Study of the permeability of tubular mineral membranes: application to wastewater treatment.

Heliyon 2021 Apr 19;7(4):e06837. Epub 2021 Apr 19.

Laboratory of Materials, Membranes and Nanotechnology, Department of Chemistry, Faculty of Sciences, Moulay Ismail University, PB 11201, Zitoune, Meknes, Morocco.

This research work opens up the possibility of developing tubular mineral membranes from Moroccan clay powders and their use in water permeability tests and wastewater treatment. The aim is to show the possibility of using clay as a low-cost raw material for the production of ceramic membranes with high mechanical and chemical performances. In a first step, we developed ceramic membranes by extruding a prepared plastic paste with the addition of an optimized amount of wood powder as organic matter (OM) to improve the porosity characteristics of the final products after firing. Read More

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Utilization of Spent FCC Catalyst as Fine Aggregate in Non-sintered Brick: Alkali Activation and Environmental Risk Assessment.

Front Chem 2021 26;9:674271. Epub 2021 Apr 26.

State Key Laboratory of Safety and Control for Chemicals, SINOPEC Research Institute of Safety Engineering, Qingdao, China.

This study focuses on the recycling of a spent fluid catalytic cracking (FCC) catalyst to produce catalyst-based non-sintered bricks (CN-bricks) for the recovery of its aluminosilicate components and the solidification of heavy metals. The effects of the content of cement (10-20%), the proportion of FCC (10-40%), and the type of an activator (NaOH/NaSiO/NaSO) on the performance of a CN-brick were investigated in terms of the mechanical strength and leaching behavior. The results show that an optimal binder system of 20% cement + NaSO could promote the compressive strength up to 42. Read More

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Effects of physical activity on quality of life and physical function in postoperative patients with gastrointestinal cancer.

Phys Ther Res 2021 26;24(1):43-51. Epub 2020 Oct 26.

Graduate School of Health Sciences, Hirosaki University, Japan.

Objectives: This study was to clarify changes in physical function and quality of life (QOL) for postoperative, and to examine the influence of the amount of physical activity on these variables.

Methods: This study included 29 patients who underwent gastrointestinal cancer surgery. The QOL measurement was used to the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for preoperative and 2nd and 4th postoperative weeks. Read More

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October 2020

Effect of a temporary sealing material on the bond strength of CAD/CAM inlay restorations with resin-coating technique.

Dent Mater J 2021 May 11. Epub 2021 May 11.

Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU).

This study aimed to assess the effects of a temporary sealing material and cleaning method of resin-coated dentin on the bond strength of computer-aided design/computer-aided manufacturing (CAD/CAM) inlay restorations. Resin-coated dentin surfaces were unsealed or temporarily sealed for 1 h or 1 week. For the temporarily sealed group, a hydraulic temporary sealing material was removed and further divided into four groups: without cleaning, cleaned with a rotational brush, a universal cleaner or an air-polishing device. Read More

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Luminescence Properties of InGaN/GaN Green Light-Emitting Diodes with Si-Doped Graded Short-Period Superlattice.

J Nanosci Nanotechnol 2021 Nov;21(11):5648-5652

Department of Physics, Kangwon National University, Chuncheon 24341, Republic of Korea.

The optical properties of InGaN/GaN green light-emitting diodes (LEDs) with an undoped graded short-period superlattice (GSL) and a Si-doped GSL (SiGSL) were investigated using photoluminescence (PL) and time-resolved PL spectroscopies. For comparison, an InGaN/GaN conventional LED (CLED) without the GSL structure was also grown. The SiGSL sample showed the strongest PL intensity and the largest PL peak energy because of band-filling effect and weakened quantum- confined stark effect (QCSE). Read More

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November 2021

A Simple and Low-Cost Method for Fabrication of Polydimethylsiloxane Microfludic Chips.

J Nanosci Nanotechnol 2021 Nov;21(11):5635-5641

Key Laboratory of Computerized Numerical Control Equipment Reliability, Ministry of Education, School of Mechanical and Aerospace Engineering, Jilin University, Changchun 130012, China.

The conventional fabrication methods for enrichment microfluidic devices require cleanroom, which are costly and time-consuming. Developing a facile and low-cost method to fabricate microfluidic chips could stimulate the progress of the applications of those chips. Here, we present an easy method for fabrication of a complete PDMS (Polydimethylsiloxane) microfluidic chip used for ion and protein enrichment. Read More

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November 2021

Sustained bimatoprost release using gold nanoparticles laden contact lenses.

J Biomater Sci Polym Ed 2021 May 12:1-14. Epub 2021 May 12.

Department of Ophthalmology, The 942 Hospital of Chinese PLA, Shengli South Street, Xingqing District, Yinchuan City, Ningxia Hui Autonomous Region, 750004, China.

Contact lenses are ideally suited for sustained ocular drug delivery to bypass the issues associated with eye drop therapy. However, drugs such as bimatoprost loaded by the conventional soaking method show poor drug uptake, high burst release, and altered critical lens properties. In this study, the effect of gold nanoparticles (GNPs) on bimatoprost loading/uptake from the soaking solution and its release kinetics from the lens was investigated. Read More

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Electrostatic perturbations from the protein affect C-H bond strengths of the substrate and enable negative catalysis in the TmpA biosynthesis enzyme.

Chemistry 2021 May 12. Epub 2021 May 12.

University of Manchester, Manchester Institute of Biotechnology, 131 Princess Street, M1 7DN, Manchester, UNITED KINGDOM.

The nonheme iron dioxygenase 2-(trimethylammonio)-ethylphosphonate dioxygenase (TmpA) is an enzyme involved in the regio- and chemoselective hydroxylation at the C 1 -position of the substrate as part of the biosynthesis of glycine betaine in bacteria and carnitine in humans. To understand how the enzyme avoids breaking the weak C 2 -H bond in favor of C 1 -hydroxylation, we set up a cluster model of 242 atoms representing the first and second-coordination sphere of the metal center and substrate binding pocket and investigated possible reaction mechanisms of substrate activation by an iron(IV)-oxo species by density functional theory methods. In agreement with experimental product distributions, the calculations predict a favorable C 1 -hydroxylation pathway. Read More

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Can physical activity levels and relationships with energy expenditure change the clinical aspects of sarcopenia and perceptions of falls among elderly women? Observational cross-sectional study.

Sao Paulo Med J 2021 May 10. Epub 2021 May 10.

MD, PhD. Professor and Coordinator of the Biomechanics and Musculoskeletal Rehabilitation Laboratory, Postgraduate Health Science Department, Medical School, Universidade Santo Amaro (UNISA), São Paulo (SP), Brazil; and Postdoctoral Student, Medical School, Universidade de São Paulo (USP), São Paulo (SP), Brazil.

Background: Physical activity (PA) is an effective strategy for managing sarcopenia in the elderly, but few studies have addressed PA levels regarding age-related changes.

Objective: To ascertain the effects of elderly women's PA levels on sarcopenia, physical performance, handgrip strength and perception of the risk of falling, and their relationship with energy expenditure.

Design And Setting: Observational cross-sectional study conducted in the southern region of the city of São Paulo, Brazil. Read More

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Physicomechanical performance and encapsulation efficiency of β-cyclodextrin loaded functional electrospun mats based on aliphatic polyesters and their blends.

J Biomater Sci Polym Ed 2021 May 12:1-14. Epub 2021 May 12.

Department of Materials Science and Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.

Designing complex-forming biodegradable and biocompatible electrospun mats (EMs) by incorporating β- cyclodextrin (β-CD) into polylactic acid PLA)/poly(ε-caprolactone) (PCL) (70:30 w/w) blend based polyester matrix. The influence of β-CD loading on the morphological, thermal, and microstructural properties was investigated using scanning electron microscopy (SEM), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). The studies revealed the presence of characteristic interactions between the polymer matrix and β-CD moieties. Read More

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Moderators of strength gains and hypertrophy in resistance training: A systematic review and meta-analysis.

J Sports Sci 2021 May 12:1-10. Epub 2021 May 12.

Laboratory of Physical Activity and Health Promotion, University of Rio de Janeiro State, Rio de Janeiro, Brazil.

This meta-analysis investigated the role of resistance training (RT) moderators on strength and muscle mass gains in untrained young (YG) and older (OG) adults. Electronic databases were searched for randomised controlled trials simultaneously assessing muscle strength and mass. Effect sizes (ES) reflecting improvements in strength and muscle mass were found for all moderators in YG and OG (ES 0. Read More

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Endocytosis induction by high-pulsed magnetic fields to overcome cell membrane barrier and improve chemotherapy efficiency.

Electromagn Biol Med 2021 May 12:1-8. Epub 2021 May 12.

Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Cell membrane acts as a barrier to the entry of impermeable drugs into cells. Recent studies have suggested that using magnetic fields can enable molecules to overcome the cell membrane barrier. However, the mechanism of membrane permeabilization remains unclear. Read More

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Extracellular Vesicles from Child Gut Microbiota Enter into Bone to Preserve Bone Mass and Strength.

Adv Sci (Weinh) 2021 05 17;8(9):2004831. Epub 2021 Feb 17.

Department of Orthopedics Xiangya Hospital Central South University Changsha Hunan 410008 China.

Recently, the gut microbiota (GM) has been shown to be a regulator of bone homeostasis and the mechanisms by which GM modulates bone mass are still being investigated. Here, it is found that colonization with GM from children (CGM) but not from the elderly (EGM) prevents decreases in bone mass and bone strength in conventionally raised, ovariectomy (OVX)-induced osteoporotic mice. 16S rRNA gene sequencing reveals that CGM reverses the OVX-induced reduction of (). Read More

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Effect of heat input on interfacial characterization of the butter joint of hot-rolling CP-Ti/Q235 bimetallic sheets by Laser + CMT.

Sci Rep 2021 May 11;11(1):10020. Epub 2021 May 11.

Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.

Composite structures made of 2 mm-thick titanium and 10 mm-thick carbon steel are widely used in infrastructures such as long-distance gas transportation. However, cracking, which is caused by intermetallic compounds (ICs), is a dominate failure mode in welds of this structure. Thus, a common way to improve the in-service life of is reduce the number of ICs. Read More

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Impact of Protein Intake during Weight Loss on Preservation of Fat-Free Mass, Resting Energy Expenditure, and Physical Function in Overweight Postmenopausal Women: A Randomized Controlled Trial.

Obes Facts 2021 May 11:1-12. Epub 2021 May 11.

Fulda University of Applied Sciences, Fulda, Germany.

Introduction: Weight loss in old age increases the risk of sarcopenia caused by the age-related reduction of fat-free mass (FFM). Due to the strong correlation between FFM and resting energy expenditure (REE), the maintenance of this must also be considered. Besides, the physical function (PF) must be maintained. Read More

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Higher body mass index and body fat percentage correlate to lower joint and functional strength in working age adults.

Appl Ergon 2021 May 8;95:103453. Epub 2021 May 8.

Department of Kinesiology, University of Waterloo, Canada. Electronic address:

As the prevalence of obesity grows worldwide, it becomes an increasing concern in working populations. Ergonomists are faced with the challenge of accommodating workplace layouts to include this worker demographic. This study investigated the relationship between shoulder and low back isometric joint strengths across body mass index (BMI) groups. Read More

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A three-dimensional scar assessment tool for keloid scars: Volume, erythema and melanin quantified.

Skin Res Technol 2021 May 11. Epub 2021 May 11.

Department of Plastic and Reconstructive Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK.

Background: There is no non-invasive objective assessment tool to measure keloid scar characteristics over time. This study aimed to ascertain the ability of the Antera 3D camera to detect differences in keloid features pre- and post-steroid injection. In order to identify whether those variation could be considered as treatment response predicting factors. Read More

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Speed agility trends in children according to growth.

Ann Hum Biol 2021 May 11:1-26. Epub 2021 May 11.

Faculty of Education, Health and Wellbeing, University of Wolverhampton, Walsall WV1 1SB, UK.

Background: Speed agility is considered as the whole assessment of speed of movement, agility and coordination. The 10x4m test has been broadly used to evaluate physical fitness and overall health in children of developmental ages. A myriad of studies have investigated the ecology of speed agility (SA). Read More

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The handgrip strength and risk of depressive symptoms: a meta-analysis of prospective cohort studies.

Qual Life Res 2021 May 1. Epub 2021 May 1.

Department of Epidemiology, School of Medicine, Jinan University, 601 West Huangpu Road, Guangzhou, 510632, Guangdong, China.

Purpose: Many studies have investigated the association between handgrip strength (HGS) and depressive symptoms, but the conclusion remain controversial. We performed a meta-analysis to evaluate the longitudinal association between HGS and risk of depressive symptoms.

Methods: PubMed, PSYCINFO and EMBASE databases were searched for eligible publications up to April 2020. Read More

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Efficient electrotransformation of Rhodococcus ruber YYL with abundant extracellular polymeric substances via a cell wall-weakening strategy.

FEMS Microbiol Lett 2021 May 11. Epub 2021 May 11.

MOE Laboratory of Biosystem Homeostasis and Protection, College of Life Sciences, Zhejiang University, Hangzhou, China.

Rhodococcus spp. have broad potential applications related to the degradation of organic contaminants and the transformation or synthesis of useful compounds. However, some Gram-positive bacteria are difficult to manipulate genetically due to low transformation efficiency. Read More

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Normalisation of glucose metabolism by Exendin-4 in the chronic phase after stroke promotes functional recovery in male diabetic mice.

Br J Pharmacol 2021 May 10. Epub 2021 May 10.

NeuroCardioMetabol Group, Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, 118 83, Stockholm, Sweden.

Background And Purpose: Glucagon-like peptide-1 receptor (GLP-1R) activation decreases stroke risk in people with type 2 diabetes (T2D) while animal studies have shown the efficacy of this strategy to counteract stroke-induced acute brain damage. However, whether GLP-1R activation also improves stroke recovery in the chronic phase after stroke is unknown. We investigated whether post-acute, chronic administration of the GLP-1R agonist Exendin-4 improves post-stroke recovery and examined possible underlying mechanisms in T2D and non-T2D mice. Read More

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Evaluation of grain boundaries as percolation pathways in quartz-rich continental crust using Atomic Force Microscopy.

Sci Rep 2021 May 10;11(1):9831. Epub 2021 May 10.

Department of Geology and Geophysics, IIT Kharagpur, Kharagpur, West Bengal, 721 302, India.

Hydrous fluids play a vital role in the chemical and rheological evolution of ductile, quartz-bearing continental crust, where fluid percolation pathways are controlled by grain boundary domains. In this study, widths of grain boundary domains in seven quartzite samples metamorphosed under varying crustal conditions were investigated using Atomic Force Microscopy (AFM) which allows comparatively easy, high magnification imaging and precise width measurements. It is observed that dynamic recrystallization at higher metamorphic grades is much more efficient at reducing grain boundary widths than at lower temperature conditions. Read More

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Postoperative Rehabilitation of Anterior Cruciate Ligament Reconstruction: A Systematic Review.

Sports Med Arthrosc Rev 2021 Jun;29(2):63-80

Orthopaedic Surgery Residency Program, Georgetown University Hospital, Washington, DC.

Recent studies have investigated the various components of postoperative rehabilitation protocols following anterior cruciate ligament reconstruction (ACLR). The objective of this article was to access and summarize the latest evidence for postoperative rehabilitation protocols following ACLR to evaluate common timeframes, number of phases, exercises, as well as the length of rehabilitation protocol. Common interventions include vibration training, open-chain and closed-chain exercises, electrical stimulation, postoperative bracing, and aquatic therapy. Read More

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Are weak or negative clinical recommendations associated with higher geographical variation in utilisation than strong or positive recommendations? Cross-sectional study of 24 healthcare services.

BMJ Open 2021 May 10;11(5):e044090. Epub 2021 May 10.

Division of Occupational and Environmental Medicine, Department of Epidemiology, Epidemiology, Biostatistics & Prevention Institute, University of Zurich and University Hospital Zurich, Zurich, Switzerland.

Objectives: When research evidence is lacking, patient and provider preferences, expected to vary geographically, might have a stronger role in clinical decisions. We investigated whether the strength or the direction of recommendation is associated with the degree of geographic variation in utilisation.

Design: In this cross-sectional study, we selected 24 services following a comprehensive approach. Read More

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Molecular self-diffusion in internal magnetic fields of porous medium investigated by NMR MGSE method.

J Magn Reson 2021 Apr 20;328:106981. Epub 2021 Apr 20.

University of Ljubljana, Faculty of Mathematics and Physics, Physics Department, Jadranska 19, 1000 Ljubljana, Slovenia.

Inhomogeneous magnetic fields generated in porous media due to differences in magnetic susceptibility at solid/liquid interfaces and due to intrinsic or artificially doped magnetic impurities can be used to gain insight into the molecular dynamics of fluid in the structure of a porous medium using the concept of NMR modulated gradient spin echo method. We extended the theory of this method to the case of an inhomogeneous magnetic field that cannot be approximated by an uniform gradient, in order to explain the CPMG measurements of self-diffusion in water soaked ceramics, which are doped with magnetic impurities of different contents. The new interpretation provides the spin relaxation times, the average pore size and their distribution, as well as the strength of the internal magnetic gradient fields in the doped ceramics. Read More

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