1,061 results match your criteria strehl ratio

Individualized tissue-engineered veins as vascular grafts: a proof of concept study in pig.

J Tissue Eng Regen Med 2021 Jul 27. Epub 2021 Jul 27.

Sahlgrenska Academy, Molecular and Clinical Medicine, Gothenburg.

Personalized tissue engineered vascular grafts are a promising advanced therapy medicinal product (ATMP) alternative to autologous or synthetic vascular grafts utilized in blood vessel bypass or replacement surgery. We hypothesized that an individualized tissue engineered vein (P-TEV) would make the body recognize the transplanted blood vessel as autologous, decrease the risk of rejection and thereby avoid lifelong treatment with immune suppressant medication as is standard with allogenic organ transplantation. To individualize blood vessels, we decellularized vena cava from six deceased donor pigs and tested them for cellular removal and histological integrity. Read More

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Expression of RUNX1-JAK2 in Human Induced Pluripotent Stem Cell-Derived Hematopoietic Cells Activates the JAK-STAT and MYC Pathways.

Int J Mol Sci 2021 Jul 15;22(14). Epub 2021 Jul 15.

St. Anna Children's Cancer Research Institute (CCRI), 1090 Vienna, Austria.

A heterogeneous genetic subtype of B-cell precursor acute lymphoblastic leukemia is driven by constitutive kinase-activation, including patients with JAK2 fusions. In our study, we model the impact of a novel JAK2 fusion protein on hematopoietic development in human induced pluripotent stem cells (hiPSCs). We insert the fusion into one endogenous allele through employing in trans paired nicking genome editing. Read More

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Higher order aberrations and retinal image quality during short-term accommodation in children.

Vision Res 2021 Jul 19;188:74-84. Epub 2021 Jul 19.

Queensland University of Technology, Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research, Brisbane, Queensland, Australia.

Changes in higher order aberrations (HOA's) and retinal image quality during accommodation have not previously been examined in children. This study measured ocular HOA's in ninety non-myopic, school-aged children during short-term accommodation tasks at 0, 3, 6, and 9 D demands presented via a Badal optometer mounted to a Hartmann-Shack wavefront aberrometer (COAS-HD, Wavefront Sciences). Eighty-four participants who exhibited active accommodation were included in the analyses. Read More

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Adaptive optics model characterizing turbulence mitigation for free space optical communications link budgets.

Opt Express 2021 Jun;29(13):20307-20321

Free-space optical communications (FSOC) is becoming an important option for both atmospheric and space-based high data rate networks. Long-range, mobile FSOC links in the former environments must mitigate the effects of turbulence if they are to provide reliable, high link availability under cloud-free atmospheric conditions. Adaptive optics (AO) has been proposed as one means of reducing link degradation in turbulence, but field validated AO performance models are few and not definitive. Read More

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Full-Diffractive Multifocal Intraocular Lens Posterior Optic Capture for Selected Pediatric Cataracts.

J Refract Surg 2021 Jun 1;37(6):390-397. Epub 2021 Jun 1.

Purpose: To evaluate the short-term outcomes of implantation of a full-diffractive multifocal intraocular lens (IOL) with optic capture for selected pediatric cataracts.

Methods: In this prospective study, patients with pediatric cataract aged 3 to 14 years were selected to receive multifocal IOL (Tecnis ZMB00; Abbott Medical Optics) posterior optic capture. Visual acuity, stereopsis, visual quality, and complications were assessed. Read More

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Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism.

FASEB J 2021 07;35(7):e21684

Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

Adenine nucleotides represent crucial immunomodulators in the extracellular environment. The ectonucleotidases CD39 and CD73 are responsible for the sequential catabolism of ATP to adenosine via AMP, thus promoting an anti-inflammatory milieu induced by the "adenosine halo". AMPD2 intracellularly mediates AMP deamination to IMP, thereby both enhancing the degradation of inflammatory ATP and reducing the formation of anti-inflammatory adenosine. Read More

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Beam propagation simulation of phased laser arrays with atmospheric perturbations.

Appl Opt 2021 Jun;60(17):5117-5123

Directed energy phased array (DEPA) systems have been proposed for applications such as beaming optical power for electrical use on remote sensors, rovers, spacecraft, and future moon bases, as well as for planetary defense against asteroids and photonic propulsion up to relativistic speeds. All such scenarios involve transmission through atmosphere and beam perturbations due to turbulence that must be quantified. Numerical beam propagation and feedback control simulations were performed using an algorithm optimized for efficient calculation of real-time beam dynamics in a Kolmogorov atmosphere. Read More

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Simplified sensitivity analysis of coherent beam combining in a tiled aperture architecture.

Appl Opt 2021 Jun;60(17):5012-5019

We propose a simple analytical-numerical model for simplified sensitivity analysis of coherent beam combining of several dozens of emitters arranged in 2D tiled architecture. The main findings are as follows: (i) regarding phase/piston error, the performance does not depend on the number of emitters and particular amplitude profiles and fulfills the Maréchal formula; (ii) regarding tilt mismatch, the performance does not depend on the number of emitters; however, the effect of amplitude profile has to be taken into account; and (iii), regarding wavefront aberration, the Strehl ratio drop is dominant and fulfills the Maréchal formula as well. Read More

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Depth of field measures in pseudophakic eyes implanted with different type of presbyopia-correcting IOLS.

Sci Rep 2021 Jun 8;11(1):12081. Epub 2021 Jun 8.

Department of Optics, Pharmacology and Anatomy, University of Alicante, Crta San Vicente del Raspeig s/n, 03690, San Vicente del Raspeig, Alicante, Spain.

To evaluate depth of field (DOF) provided by different presbyopia-correcting intraocular lens (IOL) designs, comparing the results obtained using different criteria for defining the defocus tolerance. A total of 150 eyes undergoing cataract surgery were enrolled and divided into 6 groups depending on the IOL implanted: AT.LISA Tri (Carl Zeiss Meditec), FineVision (PhysIOL), PanOptix (Alcon Laboratories), Tecnis Symfony (Johnson & Johnson Vision), Miniwell (SIFI MedTech) and Tecnis Synergy (Johnson & Johnson Vision). Read More

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Comparison of the visual performance of iris-fixated phakic lens and implantable collamer lens to correct high myopia.

BMC Ophthalmol 2021 Jun 2;21(1):244. Epub 2021 Jun 2.

Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology Tianjin Medical University, Tianjin Eye Institute, No. 4 Gansu Road, Heping District, Tianjin, 300020, China.

Background: To compare visual performance between the iris-fixated phakic intraocular len (pIOL) and implantable collamer len (ICL) to correct high myopia.

Methods: Twenty-four eyes underwent iris-fixated pIOL implantation and 24 eyes underwent ICL implantation. At the 6-month follow-up, the best-corrected visual acuity (BCVA) and uncorrected distance visual acuity (UDVA) were compared between the iris-fixated pIOL and ICL groups. Read More

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Optical and visual quality comparison of implantable collamer lens and femtosecond laser assisted laser keratomileusis for high myopia correction.

Int J Ophthalmol 2021 18;14(5):737-743. Epub 2021 May 18.

Center for Ophthalmic Optics, Hunan Provincial People's Hospital; the First Affiliated Hospital of Hunan Normal University, Changsha 410005, Hunan Province, China.

Aim: To compare clinical outcomes and refractive stability of implantable collamer lens (ICL) implantation and femtosecond laser assisted laser keratomileusis (FS-LASIK) for high myopia correction.

Methods: The Optical Quality Analysis System (OQAS) was used to evaluate clinical outcomes objectively after operation for high myopia correction. We compared the two procedures in terms of 1-year changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), safety index, efficacy index, spherical equivalent, modulation transfer function (MTF) cutoff frequency, strehl ratio (SR) and objective scatter index (OSI). Read More

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Comparison of small incision lenticule extraction and transepithelial photorefractive keratectomy in terms of visual quality in myopia patients.

Acta Ophthalmol 2021 May 12. Epub 2021 May 12.

Wenzhou Medical University Eye Hospital, Wenzhou, China.

Purpose: To comprehensively compare visual quality between small incision lenticule extraction (SMILE) and transepithelial photorefractive keratectomy (tPRK).

Methods: Sixty-four eyes in the SMILE group and 42 eyes in the tPRK group were enrolled in this study. In both groups, visual acuity, manifest refraction, higher-order aberrations (HOAs), contrast sensitivity (CS) at four spatial frequencies (3, 6, 12, 18 c/d) under three conditions (photopic, low glare, high glare), the cut-off value of the modulation transfer function (MTFcut-off), the objective scatter index (OSI) and the Strehl ratio (SR) were measured preoperatively and 1, 3 and 6 months postoperatively. Read More

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Compression Factor and Visual Performance in Adults Treated With Orthokeratology.

Eye Contact Lens 2021 07;47(7):413-419

Department of Optometry and Visual Science (Y.H.), West China School of Medicine, Sichuan University, Chengdu, China; Department of Ophthalmology (L.L.), West China Hospital, Sichuan University, Chengdu, China; and Contact Lens and Visual Optics Laboratory (S.J.V.), Centre for Vision and Eye Research, School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Australia.

Objectives: To investigate the effect of compression factor on visual performance in orthokeratology (ortho-k).

Methods: Myopic adults were fitted with ortho-k lenses with either a 0.75 diopter (D) or 1. Read More

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Influence of mild non-foveal involving epiretinal membrane on visual quality in eyes with multifocal intraocular lens implantation.

Graefes Arch Clin Exp Ophthalmol 2021 May 8. Epub 2021 May 8.

Keye Eye Center, 326 Teheran-ro, Gangnam-gu, Seoul, Korea.

Purpose: To determine the influence of mild non-foveal involving epiretinal membrane (ERM) on visual outcome in eyes with multifocal intraocular lens (MIOL) implantation.

Methods: Patients with history of MIOL implantation were screened for the presence of ERM using spectral-domain optical coherence tomography (SD-OCT) at postoperative 6 months. Ninety-one eyes with mild non-foveal involving ERM and history of MIOL implantation were compared with 83 age-matched controls without ERM and history of MIOL implantation. Read More

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Strehl Ratio and Myopia in Chinese Adolescents: The Tuyou County Pediatric Eye (TYPE) Study.

Int J Gen Med 2021 27;14:1541-1546. Epub 2021 Apr 27.

Department of Ophthalmology, Changzhi People's Hospital, Changzhi, 046000, People's Republic of China.

Aim: To investigate the relationships between property of the visual quality, Strehl ratio (SR) and the degree of myopia.

Methods: A total of 444 anatomically normal eyes of 222 adolescents were enrolled in the TYPE study. Based on spherical equivalent (SE), subjects were divided into four groups: emmetropia/control (SE: +0. Read More

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Contralateral Eye Study of Topography Guided versus Q Value Adjusted Photorefractive Keratectomy in Myopia and Myopic Astigmatism.

Clin Ophthalmol 2021 23;15:1735-1749. Epub 2021 Apr 23.

Ophthalmology Department, Cairo University, Cairo, Egypt.

Purpose Of The Study: To compare visual outcome, higher order aberrations (HOAs) of topography guided and Q value adjusted ablation in the fellow eye of patients undergoing photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism.

Methods: Prospective randomized controlled interventional clinical study. The eyes of 52 patients undergoing PRK for myopia and astigmatism were included, that is, 104 eyes in total. Read More

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Laboratory evaluation of higher-order aberrations and light scattering in explanted opacified intraocular lenses.

Eye Vis (Lond) 2021 Apr 22;8(1):14. Epub 2021 Apr 22.

David J Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

Background: Intraocular lens (IOL) calcification is a serious condition that can only be treated by removing the clouded lens. Since explantation bears the risk of complications, it is often deferred until the patient finds the symptoms intolerable. Usually, as the IOL opacifies, visual acuity is minimally affected early on. Read More

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Progressive-toric IOL design reduces residual astigmatism with increasing pupil size: a ray-tracing simulation based on corneal topography data.

Biomed Opt Express 2021 Mar 23;12(3):1568-1576. Epub 2021 Feb 23.

The David J. Apple Center for Vision Research, Department of Ophthalmology, Heidelberg University Hospital, INF 400, 69120 Heidelberg, Germany.

Population studies indicate that astigmatism decreases from the corneal center toward the periphery. A standard toric intraocular lens (IOL) with a constant cylinder power cannot correct uniformly across this gradient. We built an astigmatic eye model based on corneal topography data. Read More

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Visual quality after implantation of trifocal intraocular lenses in highly myopic eyes with different axial lengths.

Int J Ophthalmol 2021 18;14(3):371-377. Epub 2021 Mar 18.

Department of Ophthalmology, Chengdu Aier Eye Hospital, Chengdu 610041, Sichuan Province, China.

Aim: To analyze postoperative clinical results after implantation of trifocal intraocular lenses (IOLs) in highly myopic eyes with different axial lengths (ALs).

Methods: This retrospective study describes 61 eyes of 44 patients that were implanted with trifocal diffractive IOLs (AT LISA tri 839MP). Twenty-one eyes (15 patients) were included in the AL<26 mm group, 19 eyes (13 patients) in the AL≥26 mm and <28 mm group, and 21 eyes (16 patients) in the AL≥28 mm group. Read More

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Modeling infrared behavior of multilayer diffractive optical elements using Fourier optics.

Appl Opt 2021 Mar;60(7):2037-2045

In this paper, we propose to explore the infrared (IR) behavior of multilayer diffractive optical elements (MLDOEs). IR MLDOEs are designed for the development of space instruments dedicated to Earth observation. The phase effect of the MLDOE on a paraxial plane wave is studied using exact kinoform shapes for each layer. Read More

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Linear Paired Electrolysis-Realising 200 % Current Efficiency for Stoichiometric Transformations-The Electrochemical Bromination of Alkenes.

Angew Chem Int Ed Engl 2021 Apr 24;60(18):9996-10000. Epub 2021 Mar 24.

Institut für Chemie, Universität Oldenburg, Carl-von-Ossietzky-Strasse 9-11, 26111, Oldenburg, Germany.

The generation of bromine by oxidation of bromide anions at the anode and reduction of molecular oxygen at the cathode to hydrogen peroxide resulted in the overall formation of two molecules of Br (=four electron oxidation) by passing just two electrons through the solution. The bromine was used for the bromination of alkenes and thereby a linear paired electrolysis was attained which resulted in current efficencies of up to 200 %. Also, the diiodination of cyclohexene as well as the electrophilic aromatic bromination of an electron-rich arene were realised both in 168 % current efficiencies. Read More

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Objective visual quality one year after toric IOL implantation for correction of moderate and high corneal astigmatism.

Int J Ophthalmol 2021 18;14(2):245-249. Epub 2021 Feb 18.

Eye Hospital of China Academy of Chinese Medical Sciences, Beijing 100040, China.

Aim: To compare the objective visual quality after implantation of a toric intraocular lens (IOL) in order to correct moderate or high corneal astigmatism at the one year postoperative follow-up.

Methods: From December 2017 to June 2018, 66 patients (90 eyes) with simple age-related cataract with regular corneal astigmatism greater than 1.5 D were enrolled in this prospective self-control study. Read More

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February 2021

Functional Optical Zone and Visual Quality After Small-Incision Lenticule Extraction for High Myopic Astigmatism.

Ophthalmol Ther 2021 Jun 6;10(2):273-288. Epub 2021 Feb 6.

Key NHC Key Laboratory of Myopia (Fudan University), Laboratory of Myopia, Chinese Academy of Medical Sciences, Eye and ENT Hospital of Fudan University, Shanghai, China.

Introduction: The aim of this study was to compare the functional optical zone (FOZ) after correction of high myopic astigmatism and low myopic astigmatism by small-incision lenticule extraction (SMILE).

Methods: In this prospective study, 30 patients who received SMILE for high myopic astigmatism correction (cylinderical diopters ≤ - 2.0D) were enrolled in the high astigmatism group (HA). Read More

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Comparison of posterior capsule opacification between Clareon CNA0T0 and Tecnis ZCB00 intraocular lenses.

Eur J Ophthalmol 2021 Jan 31:1120672121991718. Epub 2021 Jan 31.

Ophthalmology Department, Nuestra Señora de Gracia Hospital, Zaragoza, Spain.

Introduction: The purpose is to compare posterior capsule opacification (PCO) and its impact on vision between Clareon CNA0T0 (Alcon) and Tecnis ZCB00 intraocular lenses (IOLs) (Johnson&Johnson) 1, 6, and 12 months after implantation.

Methods: A prospective observational study was performed at the Nuestra Señora de Gracia Hospital (Zaragoza, Spain). Fifty eyes (50 patients) with Tecnis IOL (group 1) and 60 eyes (60 patients) with Clareon IOL (group 2) were enrolled. Read More

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January 2021

Visual Quality and Subjective Satisfaction in Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (UT-DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK): A Fellow-Eye Comparison.

J Clin Med 2021 Jan 22;10(3). Epub 2021 Jan 22.

Anterior Segment Department, Institut Clinic d'Oftalmologia, Hospital Clinic of Barcelona, 08036 Barcelona, Spain.

Background: To analyze objective and subjective visual quality differences between descemet membrane endothelial keratoplasty (DMEK) and ultra-thin descemet stripping automated endothelial keratoplasty (UT-DSAEK) with a paired contralateral-eye design.

Methods: A cross-sectional, comparative, and observational case series study between DMEK and UT-DSAEK were presented. Visual acuity, refractive status and corneal quality assessment were compared between both endothelial keratoplasty techniques. Read More

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January 2021

The impact of visual axis position on the optical quality after implantation of multifocal intraocular lenses with different asphericity values.

Graefes Arch Clin Exp Ophthalmol 2021 Mar 20;259(3):673-683. Epub 2021 Jan 20.

Department of Ophthalmology, Hospital Hietzing, Wolkersbergenstrasse 1, 1130, Vienna, Austria.

Purpose: To evaluate the effect of visual axis positioning on the optical performance of the Tecnis MIOL and the Diff-aA MIOL.

Methods: In this prospective, randomized comparative study, 70 eyes of 35 subjects with senile cataract were implanted with the spherical aberration-correcting diffractive, bifocal Tecnis ZLB00 IOL and 60 eyes of 30 age-matched subjects with the spherical aberration neutral, diffractive, bifocal Diffractiva IOL. Observation procedure was performed 1, 3, and 6 months postoperatively. Read More

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Influence of Reading on Smartphone Screens on Visual Optical Quality Metrics and Tear Film Stability.

Cornea 2021 Jan 18. Epub 2021 Jan 18.

Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel; Affiliated with the Hebrew University of Jerusalem; and iSEARCH, Innovation Shaarezedek Eye Advanced Research Center Hub, Jerusalem, Israel.

Purpose: To evaluate the impact of a prolonged reading session on a smartphone screen on optical quality metrics and tear film stability.

Methods: This prospective study was conducted in 41 healthy volunteers who were asked to read an article on a smartphone screen for 20 minutes. The following tests were performed before the reading task in this consecutive order and repeated after the reading task in the same order: automated noninvasive tear break-up time, optical quality assessment including Objective Scatter Index (OSI), modulation transfer function, Strehl ratio, and tear film dynamic analysis as follows: vision break-up time (VBUT) as a function of OSI changes within 20 seconds, using a double-pass aberrometer imaging system, and fluorescein tear break-up time (FBUT) measured using the slit lamp. Read More

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January 2021

Early results of circularity and centration of capsulotomy prepared by three different methods.

Int J Ophthalmol 2021 18;14(1):76-82. Epub 2021 Jan 18.

Cataract and Refractive Services, Cornea Institute, L V Prasad Eye Institute (LVPEI), Hyderabad 500034, India.

Aim: To compare the difference of capsulotomy produced by precision pulse capsulotomy (PPC), manual (M-CCC), and femtosecond laser assisted capsulotomy (FLAC) in relation to intraocular lens (IOL) centration, circularity and its effect on visual outcomes.

Methods: Prospective, non-randomized comparative study conducted at LV Prasad Eye Institute, Hyderabad, India. Sixty eyes of 52 patients were grouped into 3 (FLAC, PPC and M-CCC) based on capsulotomy techniques used. Read More

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January 2021

Balancing the brain of offenders with psychopathy? Resting state EEG and electrodermal activity after a pilot study of brain self-regulation training.

PLoS One 2021 7;16(1):e0242830. Epub 2021 Jan 7.

Institute for Medical Psychology and Behavioural Neurobiology, Eberhard-Karls-University of Tübingen, Tübingen, Germany.

Although investigation of the brains of criminals began quite early in the history of psychophysiological research, little is known about brain plasticity of offenders with psychopathy. Building on our preliminary study reporting successful brain self-regulation using slow cortical potential (SCP) neurofeedback in offenders with psychopathy, we investigated the central nervous and autonomic peripheral changes occurring after brain self-regulation in a group of severe male offenders with psychopathy. Regarding the central nervous system, an overall suppression of the psychopathic overrepresentation of slow frequency bands was found, such as delta and theta band activity, after EEG neurofeedback. Read More

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