4,124 results match your criteria strategies november

Small-scale spatial analysis shows the specular distribution of excess mortality between the first and second wave of the COVID-19 pandemic in Italy.

Public Health 2021 Mar 26;194:182-184. Epub 2021 Mar 26.

Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Via San Giacomo 12, 40126, Bologna, Italy.

Objectives: The objective of the study is to compare excess mortality (EM) patterns and spatial correlation between the first and second wave of the pandemic in Lombardy, the Italian region that paid an extremely high COVID-19-related mortality toll in March and April 2020.

Study Design: We conducted a longitudinal study using municipality-level mortality data.

Methods: We investigated the patterns and spatial correlation of EM of men aged ≥75 years during the first two pandemic waves (March-April 2020 vs November 2020) of COVID-19, using the mortality data released by the Italian National Institute of Statistics. Read More

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Outcomes of Patients With ST-Segment Elevation Myocardial Infarction Admitted During COVID-19 Pandemic Lockdown in Germany - Results of a Single Center Prospective Cohort Study.

Front Cardiovasc Med 2021 20;8:638954. Epub 2021 Apr 20.

Clinic for Internal Medicine II, University Hospital Ulm - Medical Center, Ulm, Germany.

Since the outbreak of the COVID-19 pandemic, healthcare professionals reported declining numbers of patients admitted with ST-segment myocardial infarction (STEMI) associated with increased in-hospital morbidity and mortality. However, the effect of lockdown on outcomes of STEMI patients admitted during the COVID-19 crisis has not been prospectively evaluated. A prospective, observational study on STEMI patients admitted to our tertiary care center during the COVID-19 pandemic was conducted. Read More

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Results of a tri-national online survey on the current status of sports injury prevention among members of the German-Speaking Orthopaedic Sports Medicine Society (GOTS).

Sportverletz Sportschaden 2021 May 6. Epub 2021 May 6.

Department of Orthopedics, University Medical Center, Rostock, Germany.

Objectives:  To assess the current opinions and state of knowledge in primary sports injury prevention among members of the (.

Methods:  On 21 August 2019, a web-based questionnaire was sent to the members of the tri-national society Austria, Germany and Switzerland). The survey was online until 21 November 2019 and included twenty-two questions, which were divided into five sections: 1) general importance of prevention (n = 4), 2) specifications of the study population (n = 3), 3) implementation of prevention (n = 8), 4) improvement opportunities in prevention (n = 4) and 5) future research areas (n = 3). Read More

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Risk of Recall Among Medical Devices Undergoing US Food and Drug Administration 510(k) Clearance and Premarket Approval, 2008-2017.

JAMA Netw Open 2021 May 3;4(5):e217274. Epub 2021 May 3.

Department of Orthopedic Surgery, University of Missouri-Kansas City, Kansas City.

Importance: The US Food and Drug Administration (FDA) uses 510(k) clearance and premarket approval (PMA) pathways to ensure device safety before marketing. Premarket approval evaluates high-risk medical devices and requires clinical trials, whereas 510(k) clearance evaluates moderate-risk devices and relies on benchtop (nonclinical and biomechanical) and descriptive data. Existing literature suggests that the clinical trials required by PMA are associated with reduced risk of recall compared with devices granted 510(k) clearance. Read More

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Carer reported experiences: Supporting someone with a rare disease.

Health Soc Care Community 2021 May 6. Epub 2021 May 6.

Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Institute of Clinical Science Block A, Belfast, UK.

This exploratory study aimed to gain an understanding of carer reported experiences derived specifically from persons caring for someone with a rare disease. The survey took place online on the SmartSurvey platform from November 2019 to January 2020. The facilitated workshop took place in Bangor Carnegie Library, Northern Ireland. Read More

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Caregiving Strategies in Families of Children with Congenital Heart Disease: A Qualitative Study.

Iran J Nurs Midwifery Res 2021 Jan-Feb;26(1):60-67. Epub 2021 Jan 18.

Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: The families of children with Congenital Heart Disease (CHD) experience challenges in taking care of their child, which may affect the whole family. Therefore, the families need to manage and organize the caregiving process for the child. In order to help families provide optimized and quality care for their child, it is important to understand how they manage caregiving challenges. Read More

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January 2021

Experiences of general practice care for self-harm: a qualitative study of young people's perspectives.

Br J Gen Pract 2021 May 4. Epub 2021 May 4.

Keele University, School of Medicine, Keele, United Kingdom.

Background: Self-harm is a growing concern and rates of self-harm in young people presenting to general practice are rising. There is however an absence of evidence on young people's experiences of GP care and on accessing general practice.

Aim: To explore the help-seeking behaviours, experiences of GP care, and access to general practice for young people who self-harm. Read More

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Advancing physician wellness, engagement and excellence in a mental health setting: a Canadian perspective.

Health Promot Int 2021 May 3. Epub 2021 May 3.

Centre for Addiction and Mental Health, 1001 Queen Street West, Toronto, M6J 1H4 Ontario, Canada.

This article describes the development and implementation of wellness initiatives within a large Canadian academic mental health hospital, based on the Mental Health Commission of Canada's workplace standards for mental health. To support the implementation of an organizational framework for physician wellness, a needs assessment of Centre for Addiction and Mental Health physicians (N = 181) was conducted between 21 November and 5 December 2017, including measuring physician burnout rates using two items on the Maslach Burnout Inventory tool. Based on findings, and the organizational wellness framework, a multi-pronged wellness approach was developed, improving physician supports at the individual, team and organizational levels. Read More

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Knowledge scores in annual and modular curriculum among medical students from Karachi, Pakistan.

J Pak Med Assoc 2021 Feb;71(2(B)):681-685

Liaquat National Medical College and Hospital, Karachi, Pakistan.

Objective: To compare the knowledge scores of basic medical subjects in annual versus modular system among undergraduate medical students.

Methods: A cross-sectional survey was conducted on 4th year undergraduate medical students of annual and modular system of Liaquat National Medical College, Pakistan. Study was conducted from 30th November 2017 to 1st June 2018 for a total of 6 months. Read More

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February 2021

Geriatrics: Moving forward with 2020 vision.

J Am Geriatr Soc 2021 May 3. Epub 2021 May 3.

Department of Medicine, Division of Geriatric Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Geriatricians have long debated the parameters, positioning, and prospects of their specialty. The year 2020 started full of promise as many organizations anticipated assessing themselves using perfect, or 2020, vision. While challenging on several levels, the momentous combination of events in 2020-the COVID-19 pandemic, Racial Justice Movement, and the November elections-provided Geriatric Medicine several opportunities to firmly secure a position in the mainstream. Read More

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Understanding Behavioral Intentions Toward COVID-19 Vaccines: A Theory-based Content Analysis of Tweets.

Jialin Liu Siru Liu

J Med Internet Res 2021 Apr 29. Epub 2021 Apr 29.

Department of Biomedical Informatics, University of Utah, Salt Lake City, US.

Background: Acceptance rates of COVID-19 vaccines still have not reached the threshold for herd immunity. Understanding why some people are willing to be vaccinated and others are not is a critical step to develop efficient implementation strategies to promote COVID-19 vaccines.

Objective: The objectives of this study are to: 1) determine if the adapted COM-B model can explain behavioral intentions toward COVID-19 vaccines using tweets; 2) examine theory-informed factors that might affect behavioral intentions toward COVID-19 vaccines; 3) extract themes to provide information for researchers in public health to develop theory-based and evidence-based promotion interventions. Read More

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Rates of Serious Surgical Errors in California and Plans to Prevent Recurrence.

JAMA Netw Open 2021 May 3;4(5):e217058. Epub 2021 May 3.

Department of Urology, University of California, San Francisco.

Importance: Despite widespread recognition and known harms, serious surgical errors, known as surgical never events, endure. The California Department of Public Health (CDPH) has developed an oversight system to capture never events and a platform for process improvement that has not yet been critically appraised.

Objectives: To examine surgical never events occurring in hospitals in California and summarize recommendations to prevent future events. Read More

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Connecting the Dots: a cluster-randomized clinical trial integrating standardized autism spectrum disorders screening, high-quality treatment, and long-term outcomes.

Trials 2021 May 2;22(1):319. Epub 2021 May 2.

AJ Drexel Autism Institute, Drexel University, 3020 Market Street, Philadelphia, PA, 19104, USA.

Background: Autism spectrum disorder (ASD) affects one in 54 children in the United States of America, and supporting people with ASD across the lifespan presents challenges that impact individuals, families, and communities and can be quite costly. The American Academy of Pediatrics has issued recommendations for routine ASD screening at 18 and 24 months, but some research suggests that few pediatricians perform high-fidelity, standardized screening universally. Furthermore, the United States Preventive Services Task Force (USPSTF) found insufficient evidence to recommend for or against universal ASD screening. Read More

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Pragmatic Experience with Risk-based versus Universal Hepatitis C Screening in Pregnancy: Detection of Infection and Postpartum Linkage to Care.

Am J Perinatol 2021 May 2. Epub 2021 May 2.

Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  Despite the Centers for Disease Control and Prevention (CDC) and U.S. Preventive Services Task Force (USPSTF) recommending universal hepatitis C virus (HCV) screening in pregnancy Society for Maternal-Fetal Medicine (SMFM) and American College of Obstetricians and Gynecologists (ACOG) continue to endorse risk-based screening for HCV in pregnancy. Read More

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Written Advice Given by African American Smokers to Their Peers: Qualitative Study of Motivational Messages.

JMIR Form Res 2021 Apr 30;5(4):e21481. Epub 2021 Apr 30.

Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States.

Background: Although African Americans have the lowest rates of smoking onset and progression to daily smoking, they are less likely to achieve long-term cessation. Interventions tailored to promote use of cessation resources in African American individuals who smoke are needed. In our past work, we demonstrated the effectiveness of a technology-assisted peer-written message intervention for increasing smoking cessation in non-Hispanic White smokers. Read More

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Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review.

Res Social Adm Pharm 2021 Apr 18. Epub 2021 Apr 18.

Department of Health and Social Management, University of Eastern Finland, Finland.

Objectives: Several implementation strategies can reduce potentially inappropriate medication (PIM) prescribing. Although use of PIMs has declined in recent years, it remains prevalent. Various strategies exist to improve the appropriateness of medication use. Read More

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The diffuse-type tenosynovial giant cell tumor (dt-TGCT) patient journey: a prospective multicenter study.

Orphanet J Rare Dis 2021 Apr 29;16(1):191. Epub 2021 Apr 29.

Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.

Background: Tenosynovial giant cell tumor (TGCT) is a rare, locally aggressive neoplasm arising from the synovium of joints, bursae, and tendon sheaths affecting small and large joints. It represents a wide spectrum ranging from minimally symptomatic to massively debilitating. Most findings to date are mainly from small, retrospective case series, and thus the morbidity and actual impact of this rare disease remain to be elucidated. Read More

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Comparative Yield of Tuberculosis during Active Case Finding Using GeneXpert or Smear Microscopy for Diagnostic Testing in Nepal: A Cross-Sectional Study.

Trop Med Infect Dis 2021 Apr 14;6(2). Epub 2021 Apr 14.

Birat Nepal Medical Trust, Kathmandu 44600, Nepal.

This study compared the yield of tuberculosis (TB) active case finding (ACF) interventions applied under TB REACH funding. Between June 2017 to November 2018, Birat Nepal Medical Trust identified presumptive cases using simple verbal screening from three interventions: door-to-door screening of social contacts of known index cases, TB camps in remote areas, and screening for hospital out-patient department (OPD) attendees. Symptomatic individuals were then tested using smear microscopy or GeneXpert MTB/RIF as first diagnostic test. Read More

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Digital Gene Expression Analysis of Epithelioid and Sarcomatoid Mesothelioma Reveals Differences in Immunogenicity.

Cancers (Basel) 2021 Apr 7;13(8). Epub 2021 Apr 7.

Institute of Pathology, University Hospital Essen, University of Duisburg Essen, 45147 Essen, Germany.

Malignant pleural mesothelioma (MPM) is an aggressive malignancy associated with asbestos exposure. Median survival ranges from 14 to 20 months after initial diagnosis. As of November 2020, the FDA approved a combination of immune checkpoint inhibitors after promising intermediate results. Read More

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COVID-19 Among Workers in the Seafood Processing Industry: Implications for Prevention Measures - Alaska, March-October 2020.

MMWR Morb Mortal Wkly Rep 2021 Apr 30;70(17):622-626. Epub 2021 Apr 30.

Large COVID-19 outbreaks have occurred in high-density workplaces, such as food processing facilities (1). Alaska's seafood processing industry attracts approximately 18,000 out-of-state workers annually (2). Many of the state's seafood processing facilities are located in remote areas with limited health care capacity. Read More

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Emerging antibody-based therapeutics against SARS-CoV-2 during the global pandemic.

Antib Ther 2020 Dec 24;3(4):246-256. Epub 2020 Nov 24.

Antibody Engineering Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

SARS-CoV-2 antibody therapeutics are being evaluated in clinical and preclinical stages. As of 11 October 2020, 13 human monoclonal antibodies targeting the SARS-CoV-2 spike protein have entered clinical trials with three (REGN-COV2, LY3819253/LY-CoV555, and VIR-7831/VIR-7832) in phase 3. On 9 November 2020, the US Food and Drug Administration issued an emergency use authorization for bamlanivimab (LY3819253/LY-CoV555) for the treatment of mild-to-moderate COVID-19. Read More

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December 2020

Effect Modification by Sex of the Hemoglobin Concentration on Frailty Risk in Hospitalized Older Patients.

Clin Interv Aging 2021 22;16:687-696. Epub 2021 Apr 22.

Department of Nursing, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.

Background: Hemoglobin concentration differs by sex, possibly affecting any association between hemoglobin and frailty. This study aimed to evaluate the potential interaction effect of hemoglobin and sex on frailty in Chinese older inpatients.

Methods: A cross-sectional study was conducted between February 2015 and November 2017 in a tertiary hospital. Read More

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Long-term patient-related quality of life after successfully treated aseptic non-unions of the long bones.

Injury 2021 Apr 16. Epub 2021 Apr 16.

Department for Trauma Surgery, University Medical Center Regensburg, Germany. Electronic address:

Background: Non-union after fracture depicts a devastating complication in trauma surgery and studies assessing patient-reported outcome measures after stable bone consolidation are rare. Therefore, we aimed to evaluate the long-term impact of aseptic long bone non-union on the patients' physical health state and psychological wellbeing. For this purpose, quality of life after successful surgical treatment of long bone non-union was assessed. Read More

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Household economic burden of childhood severe pneumonia in Bangladesh: a cost-of-illness study.

Arch Dis Child 2021 Apr 27. Epub 2021 Apr 27.

Deakin Health Economics, School of Health and Social Development, Deakin University, Geelong, Victoria, Australia.

Objective: To estimate household cost of illness (COI) for children with severe pneumonia in Bangladesh.

Design: An incidence-based COI study was performed for one episode of childhood severe pneumonia from a household perspective. Face-to-face interviews collected data on socioeconomic, resource use and cost from caregivers. Read More

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Factors associated with use of insecticide-treated net for malaria prevention in Manica District, Mozambique: a community-based cross-sectional survey.

Malar J 2021 Apr 27;20(1):200. Epub 2021 Apr 27.

Centro de Investigação Em Saúde de Manhiça (CISM), Maputo, Mozambique.

Background: Insecticide-treated net (ITN) use is crucial for preventing malaria infection. Despite significant improvements in ITN access and use over the past two decades, many malaria-endemic countries in sub-Saharan Africa have not yet reached global targets for universal coverage of ITNs. To reduce the gaps in ITN use, it is important to understand the factors associated with ITN use. Read More

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Web-Based Educational Intervention for Patients With Uninvestigated Dyspepsia Referred for Upper Gastrointestinal Tract Endoscopy: A Randomized Clinical Trial.

JAMA Intern Med 2021 Apr 26. Epub 2021 Apr 26.

Department of Gastroenterology and Hepatology, Radboud University Medical Centre, Nijmegen, the Netherlands.

Importance: Diagnostic yield of upper gastrointestinal (GI) tract endoscopy for uninvestigated dyspepsia is low, and its clinical implications are limited. There is an unmet need for better strategies to reduce the volume of upper GI tract endoscopic procedures for dyspepsia.

Objective: To study the effectiveness of a web-based educational intervention as a tool to reduce upper GI tract endoscopy in uninvestigated dyspepsia. Read More

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Acute bronchiolitis management in Tunisia: Impact of the national guidelines.

Tunis Med 2021 Feb;99(2):238-242

Background: Acute bronchiolitis management involves all pediatricians and primary care physicians. The national guidelines for bronchiolitis diagnosis and treatment were published in Tunisia to reduce excessive use of diagnostic tests and unify bronchiolitis management.

Objectives: We aimed to assess the real impact of the national guidelines on acute bronchiolitis management in Tunisia. Read More

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February 2021

An examination of socioeconomic and racial/ethnic disparities in the awareness, knowledge and utilization of three colorectal cancer screening modalities.

SSM Popul Health 2021 Jun 24;14:100780. Epub 2021 Mar 24.

Division of Health Care Policy & Research, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

While colorectal cancer (CRC) mortality rates have been decreasing, disparities by socioeconomic status (SES) and race/ethnicity persist. CRC screening rates remain suboptimal among low SES and racial/ethnic minority populations, despite the availability of multiple screening modalities. Understanding awareness, knowledge, and utilization of common screening modalities within different racial/ethnic and SES groups is critical to inform efforts to improve population screening uptake and reduce disparities in CRC-related health outcomes. Read More

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The Need for Structured Strategies to Improve Stroke Care in a Rural Telestroke Network in Northern New South Wales, Australia: An Observational Study.

Front Neurol 2021 9;12:645088. Epub 2021 Apr 9.

Hunter New England Health, Wallsend, NSW, Australia.

A telestroke network in Northern New South Wales, Australia has been developed since 2017. We theorized that the telestroke network development would drive a progressive improvement in stroke care metrics over time. This study aimed to describe changes in acute stroke workflow metrics over time to determine whether they improved with network experience. Read More

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Enabling adoption and use of new health information technology during implementation: Roles and strategies for internal and external support personnel.

J Am Med Inform Assoc 2021 Apr 24. Epub 2021 Apr 24.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Objective: Successful technological implementations frequently involve individuals who serve as mediators between end users, management, and technology developers. The goal for this project was to evaluate the structure and activities of such mediators in a large-scale electronic health record implementation.

Materials And Methods: Field notes from observations taken during implementation beginning in November 2017 were analyzed qualitatively using a thematic analysis framework to examine the relationship between specific types of mediators and the type and level of support to end users. Read More

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