243 results match your criteria strain sysu


Cysteiniphilum marinum sp. nov., isolated from coastal seawater.

Antonie Van Leeuwenhoek 2021 Apr 24. Epub 2021 Apr 24.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

Six aerobic Gram-negative bacteria were isolated from seawater in Guangdong Province, P.R. China. Read More

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ATP and NADPH engineering of Escherichia coli to improve the production of 4-hydroxyphenylacetic acid using CRISPRi.

Biotechnol Biofuels 2021 Apr 20;14(1):100. Epub 2021 Apr 20.

Institute of Synthetic Biology, Biomedical Center, Guangdong Province Key Laboratory of Improved Variety Reproduction in Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

Background: 4-Hydroxyphenylacetic acid (4HPAA) is an important raw material for the synthesis of drugs, pesticides and biochemicals. Microbial biotechnology would be an attractive approach for 4HPAA production, and cofactors play an important role in biosynthesis.

Results: We developed a novel strategy called cofactor engineering based on clustered regularly interspaced short palindromic repeat interference (CRISPRi) screening (CECRiS) for improving NADPH and/or ATP availability, enhancing the production of 4HPAA. Read More

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A LysR family transcriptional regulator modulates biofilm formation and protease production in .

Appl Environ Microbiol 2021 Apr 2. Epub 2021 Apr 2.

School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China

Quorum sensing (QS) signals are widely employed by bacteria to regulate biological functions in response to cell densities. Previous studies showed that mostly utilizes two types of QS systems, including the -acylhomoserine lactone (AHL) and -2-dodecenoic acid (BDSF) systems, to regulate biological functions. We demonstrated here that a LysR family transcriptional regulator Bcal3178 controls the QS-regulated phenotypes, including biofilm formation and protease production, in H111. Read More

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Aquiflexum lacus sp. nov., isolated from a lake sediment sample.

Arch Microbiol 2021 Mar 24. Epub 2021 Mar 24.

State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.

A novel Gram-staining negative, crescent-like or rod-shaped, non-motile bacterium, designated strain CUG 91378, was isolated from a sediment sample of Qinghai Lake, Qinghai Province, China. The strain was red-colored, and catalase- and oxidase-positive. Strain CUG 91378 was able to grow at 15-37 °C (optimum, 28 °C), pH 7-9 (pH 7. Read More

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gen. nov., sp. nov., a new actinobacterium isolated from hot spring sediment, and emended description of the family .

Int J Syst Evol Microbiol 2019 Jun 19;71(3). Epub 2021 Mar 19.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, PR China.

One thermophilic bacterium, designated strain SYSU G02662, was isolated from hot spring sediment sampled in Tibet, PR China. Polyphasic taxonomic analyses and whole-genome sequencing were used to determine the taxonomy position of the strain. Phylogenetic analysis using 16S rRNA gene sequences indicated that strain SYSU G02662 showed the highest sequence similarity to SCSIO 58843 (95. Read More

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Chthonobacter rhizosphaerae sp. nov., a bacterium isolated from rhizosphere soil of Citrus sinenesis.

Arch Microbiol 2021 Mar 2. Epub 2021 Mar 2.

China Tobacco Yunnan Industrial Co. Ltd., Kunming, 650231, People's Republic of China.

A Gram-staining negative, facultative anaerobic, motile and short rod-shaped bacterium, designated strain yh7-1, was isolated from rhizosphere soil of Citrus sinenesis collected from the garden of Citrus sinenesis in Ailao Mountain, south-west China. Cells grew at 15-45 °C, pH 5.0-9. Read More

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Identification of cardiovascular abnormalities by multiparametric magnetic resonance imaging in end-stage renal disease patients with preserved left ventricular ejection fraction.

Eur Radiol 2021 Feb 24. Epub 2021 Feb 24.

Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

Objectives: Our study aimed to evaluate myocardial strain and tissue characteristics by multiparametric cardiovascular magnetic resonance (CMR) imaging in end-stage renal disease (ESRD) patients on peritoneal dialysis with preserved left ventricular ejection fraction (LVEF).

Methods: ESRD patients on peritoneal dialysis with echocardiographic LVEF > 50% and age- and sex-matched healthy volunteers underwent multiparametric CMR at 3 T. LV function, LV myocardial native T1 and T2, and biventricular strain were measured and compared between the patients and controls. Read More

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February 2021

Profiling of alternative polyadenylation and gene expression in PEDV-infected IPEC-J2 cells.

Virus Genes 2021 Apr 23;57(2):181-193. Epub 2021 Feb 23.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.

Since 2010, porcine epidemic diarrhea virus (PEDV) has received global attention with the emergence of variant strains characterized with high pathogenicity. The pathogen-host interaction after PEDV infection is still unclear. To investigate this issue, high-throughput-based sequencing technology is one of the optimal choices. Read More

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Thermaurantiacus tibetensis gen. nov., sp. nov., a novel moderately thermophilic bacterium isolated from hot spring microbial mat in Tibet.

Antonie Van Leeuwenhoek 2021 Apr 23;114(4):445-455. Epub 2021 Feb 23.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

Two bacterial strains SYSU G02173 and SYSU G03142 were isolated from hot springs in Tibet, China. Based on the results of nearly full-length 16S rRNA gene sequences and phylogenetic analyses, strains SYSU G02173 and SYSU G03142 were assigned to the family Sphingosinicellaceae, and were closest to Sandaracinobacter sibiricus RB16-17 (96.04% and 96. Read More

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Siccirubricoccus phaeus sp. nov., isolated from oil reservoir water and emended description of the genus Siccirubricoccus.

Antonie Van Leeuwenhoek 2021 Apr 6;114(4):355-364. Epub 2021 Feb 6.

State Key Laboratory of Agrobiotechnology, Department of Microbiology and Immunology, College of Biological Sciences, China Agricultural University, Beijing, 100193, People's Republic of China.

A Gram-staining-negative, non-motile, aerobic bacterium, designated 1-3, was isolated from oil reservoir water collected from Liaohe oilfield, north-east of China. Growth was observed at 15-40 °C (optimum 37 °C) and pH 6-10 (optimum 7). The strain can grow under nitrogen-limiting condition. Read More

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Neobacillus sedimentimangrovi sp. nov., a Thermophilic Bacterium Isolated from Mangrove Sediment.

Curr Microbiol 2021 Mar 4;78(3):1039-1044. Epub 2021 Feb 4.

Fujian Agricultural and Forestry University, Fuzhou, 350002, Fujian, China.

Two Gram-stain positive, rod-shaped, endospore-forming, aerobic, thermophilic strains, designated FJAT-2464 and FJAT-52740, were isolated from the sediment collected from Zhangjiang Estuary Mangrove National Nature Reserve in Fujian Province, China. The 16S rRNA gene sequence similarity between strains FJAT-2464 and FJAT-52740 was 100%. The result suggests that strains FJAT-2464 and FJAT-52740 belong to the same genome species, hence only FJAT-2464 was considered for further analysis. Read More

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Biochemical characteristics and membrane fouling behaviors of soluble microbial products during the lifecycle of Escherichia coli.

Water Res 2021 Mar 13;192:116835. Epub 2021 Jan 13.

School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou 510006, PR China; Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Guangzhou 510006, PR China. Electronic address:

The complexity of production process and chemical compositions of soluble microbial products (SMPs) largely limits the understanding of membrane fouling in membrane bioreactors (MBRs). Herein, we used a model single-strain Escherichia coli to better understand the chemical natures of SMPs and their roles in membrane fouling. The effects of carbon source and growth phase on the chemical compositions of SMPs were identified at both the compound and molecular levels by using advanced techniques including excitation emission matrix and parallel factor analysis (EEM-PARAFAC), size exclusion chromatography coupled with organic carbon detection (LC-OCD), and untargeted ultra-performance liquid chromatography - Q-Exactive - mass spectrometry (UPLC-Q-Exactive-MS). Read More

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Visualization of the Oncolytic Alphavirus M1 Life Cycle in Cancer Cells.

Virol Sin 2021 Jan 22. Epub 2021 Jan 22.

State Key Lab for Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China.

Oncolytic alphavirus M1 has been shown to selectively target and kill cancer cells, but cytopathic morphologies induced by M1 virus and the life cycle of the M1 strain in cancer cells remain unclear. Here, we study the key stages of M1 virus infection and replication in the M1 virus-sensitive HepG2 liver cancer cell line by transmission electron microscopy, specifically examining viral entry, assembly, maturation and release. We found that M1 virus induces vacuolization of cancer cells during infection and ultimately nuclear marginalization, a typical indicator of apoptosis. Read More

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January 2021

Zafaria cholistanensis gen. nov. sp. nov., a moderately thermotolerant and halotolerant actinobacterium isolated from Cholistan desert soil of Pakistan.

Arch Microbiol 2021 May 18;203(4):1717-1729. Epub 2021 Jan 18.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences,, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

A Gram-staining positive, non-spore forming, non-pigmented and non-motile bacterium, designated strain NCCP-1664, was isolated from Cholistan desert, Pakistan. Cells of strain NCCP-1664 were strictly aerobic, catalase positive and oxidase negative with a rod to coccus growth cycle and can grow at pH 6.0-9. Read More

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Ciprofloxacin-degrading Paraclostridium sp. isolated from sulfate-reducing bacteria-enriched sludge: Optimization and mechanism.

Water Res 2021 Mar 5;191:116808. Epub 2021 Jan 5.

School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou, China; Shenzhen Research Institute of Sun Yat-sen University, Shenzhen, China. Electronic address:

Ciprofloxacin (CIP), one of the most widely used fluoroquinolone antibiotics, is frequently detected in the effluents of wastewater treatment plants and aquatic environments. In this study, a CIP-degrading bacterial strain was isolated from the sulfate reducing bacteria (SRB)-enriched sludge, identified as Paraclostridium sp. (i. Read More

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Deletion of pksA attenuates the melanogenesis, growth and sporulation ability and causes increased sensitivity to stress response and antifungal drugs in the human pathogenic fungus Fonsecaea monophora.

Microbiol Res 2021 Mar 5;244:126668. Epub 2020 Dec 5.

Department of Dermatology and Venerology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. Electronic address:

Fonsecaea monophora, which is very similar to Fonsecaea pedrosoi in morphological features, has been commonly misdiagnosed as F. pedrosoi. Like F. Read More

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A highly pathogenic recombinant infectious bronchitis virus with adaptability in cultured cells.

Virus Res 2021 01 15;292:198229. Epub 2020 Nov 15.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510006, China. Electronic address:

Infectious bronchitis virus (IBV) of GI-19 (QX), GI-7 (TW), GI-13 (4/91) and GI-1 (Mass) lineages have been frequently detected in China in recent years. Here, An IBV strain, referred as GD17/04, was isolated from the dead yellow feather chicken vaccinated with H52 and 4/91 vaccines, whose genome sequence was obtained through high-throughput sequencing. Then it has been confirmed by the RDP and SimPlot analysis that GD17/04 is a recombinant strain deriving from YX10, 4/91, TW 2575/98 and H52 strains. Read More

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January 2021

Na-NQR Confers Aminoglycoside Resistance via the Regulation of l-Alanine Metabolism.

mBio 2020 11 17;11(6). Epub 2020 Nov 17.

The Third Affiliated Hospital, Sun Yat-sen University, University City, Guangzhou, People's Republic of China

Sodium-translocating NADH:quinone oxidoreductase (Na-NQR) functions as a unique redox-driven sodium pump, generating membrane potential, which is related to aminoglycoside antibiotic resistance. However, whether it modulates other metabolisms to confer antibiotic resistance is unknown. The present study showed that loss of or led to differential metabolomes with elevated resistance to aminoglycoside antibiotics. Read More

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November 2020

Biomimetic epidermal sensors assembled from polydopamine-modified reduced graphene oxide/polyvinyl alcohol hydrogels for the real-time monitoring of human motions.

J Mater Chem B 2020 12;8(46):10549-10558

School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510275, China.

Conductive hydrogel-based epidermal strain sensors can generate repeatable electrical changes upon mechanical deformations for indication of the skin's physiological condition. However, this remains challenging for many conductive hydrogel sensors due to biomechanical mismatch with skin tissues and an unstable resistance variation response, resulting in non-conformable deformations with the epidermis and dermis, and consequently generating inaccurate monitoring of human movements. Herein, a conductive hydrogel that highly matches the skin is fabricated from dynamically hydrogen-bonded nanocrystallites of polydopamine-modified reduced graphene oxide (PDA-rGO) nanosheets composited with polyvinyl alcohol, namely the PDA-rGO/PVA hydrogel. Read More

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December 2020

sp. nov. and sp. nov., two new species of bacteria belonging to the family .

Int J Syst Evol Microbiol 2020 Dec;70(12):6266-6283

Laboratory of Microbiology, Department of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung City 811, No. 142, Hai-Chuan Rd. Nan-Tzu, Kaohsiung City 811, Taiwan, ROC.

Two Gram-stain-negative, aerobic, non-motile bacteria, designated KMS-5 and CYK-10, were isolated from freshwater environments. 16S rRNA gene sequence similarity results indicated that these two novel strains belong to the family . Strain KMS-5 is closely related to species within the genus (96. Read More

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December 2020

Nesterenkonia haasae sp. nov., an alkaliphilic actinobacterium isolated from a degraded pasture in Songnen Plain.

Arch Microbiol 2021 Apr 26;203(3):959-966. Epub 2020 Oct 26.

State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

An alkaliphilic actinobacterial strain, designated Hz 6-5, was isolated from saline-alkaline soil from Songnen Plain in north-eastern China. The isolate formed light yellow-colored colonies and its cells were Gram-staining positive, non-motile, and non-spore-forming short rods. The strain was aerobic with optimal growth at 33 °C, pH 9. Read More

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The whole-genome sequencing and analysis of a Ganoderma lucidum strain provide insights into the genetic basis of its high triterpene content.

Genomics 2021 Jan 20;113(1 Pt 2):840-849. Epub 2020 Oct 20.

School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, PR China. Electronic address:

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January 2021

Bacillus alkalicellulosilyticus sp. nov., isolated from extremely alkaline bauxite residue (red mud) site.

Arch Microbiol 2021 Mar 12;203(2):719-723. Epub 2020 Oct 12.

State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, PR China.

A Gram-stain-negative, rod-shaped, facultatively anaerobic, motile and spore-forming strain designated FJAT-44921 was isolated from red mud collected from Chiping County, Shandong Province, China. The 16S rRNA gene sequence result showed that strain FJAT-44921 shared a low sequence identity (96.6%) with the members of the genus Bacillus. Read More

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Wolbachia increase germ cell mitosis to enhance the fecundity of Laodelphax striatellus.

Insect Biochem Mol Biol 2020 12 20;127:103471. Epub 2020 Sep 20.

Key Laboratory of Tropical Disease Control of the Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China. Electronic address:

Wolbachia are intracellular bacteria that infect a wide range of invertebrates and have evolved various strategies to alter host reproduction for their own survival and dissemination. In small brown planthopper Laodelphax striatellus, Wolbachia-infected females lay more eggs than uninfected females. Our previous study has shown that Wolbachia are abundant in ovarian cells of L. Read More

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December 2020

gen. nov., sp. nov., a novel cellulose- and xylan-degrading member of the family isolated from a hot spring.

Int J Syst Evol Microbiol 2020 Nov;70(11):5717-5724

State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, PR China.

Two anaerobic bacteria, designated strains SYSU GA16112 and SYSU GA16107, were isolated from a hot spring in Tengchong County, Yunnan Province, south-west PR China. Phylogenetic analyses based on 16S rRNA gene sequences showed that strains SYSU GA16112 and SYSU GA16107 belong to the family . Cells of strains SYSU GA16112 and SYSU GA16107 were Gram-stain-negative, rod-shaped and non-motile. Read More

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November 2020

Isolation of Clostridium from Yunnan-Tibet hot springs and description of Clostridium thermarum sp. nov. with lignocellulosic ethanol production.

Syst Appl Microbiol 2020 Sep 21;43(5):126104. Epub 2020 Jun 21.

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China. Electronic address:

Lignocellulose is considered a major source of renewable energy that serve as an alternative to the fossil fuels. Members of the genus Clostridium are some of the many microorganisms that have the ability to degrade lignocellulose efficiently to sugar, which can be further converted to biofuel. In this study, we isolated twelve Clostridium strains from hot spring samples of Yunnan and Tibet, of which isolates SYSU GA15002 and SYSU GA17076 showed low 16S rRNA gene sequence identity profiles to any of the validly named Clostridium strains (<94. Read More

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September 2020

Quantitative secretome analysis of polymyxin B resistance in Escherichia coli.

Biochem Biophys Res Commun 2020 09 6;530(1):307-313. Epub 2020 Aug 6.

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. Electronic address:

Bacterial resistance has become a serious threat to human health. In particular, the gradual development of resistance to polymyxins, the last line of defense for human infections, is a major issue. Secreted proteins contribute to the interactions between bacteria and the environment. Read More

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September 2020

Biofilm for leaching precious metals from waste printed circuit boards using biocyanidation technology.

J Hazard Mater 2021 02 4;403:123586. Epub 2020 Aug 4.

School of Environmental Science and Engineering, Sun Yat-Sen University, 135 Xingang Xi Road, Guangzhou, 510275, People's Republic of China. Electronic address:

Presently, biocyanidation technology is being usually adopted to recover precious metals from an increasing quantity of waste printed circuit boards. The main aim of this work was to investigate the biofilm formation of Pseudomonas and its ability to leach precious metals. Based on batch experiments, strain 113 showed the highest biofilm-forming activity in optimal culture conditions of pH 7. Read More

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February 2021

Sphingomonas hominis sp. nov., isolated from hair of a 21-year-old girl.

Antonie Van Leeuwenhoek 2020 Oct 11;113(10):1523-1530. Epub 2020 Aug 11.

State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

A Gram-stain-negative, aerobic, motile strain, HHU CXW, was isolated from hair of a healthy 21-year-old female student of Hohai University, Nanjing, China. The 16S rRNA gene sequence analysis indicated that HHU CXW represents a member of the genus Sphingomonas with the highest sequence similarity (97.6%) to the type strain S. Read More

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October 2020

Sphingobacterium endophyticum sp. nov., a novel endophyte isolated from halophyte.

Arch Microbiol 2020 Dec 31;202(10):2771-2778. Epub 2020 Jul 31.

State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.

A bacterial strain designated NYYP31 was isolated from the leaves of an annual halophytes, Suaeda corniculata Bunge, collected from the southern edge of the Gurbantunggut desert, north-west China. Strain NYYP31 was Gram-staining negative, strictly aerobic, rod-shaped, non-motile, and non-spore-forming. Growth was observed at 4-42 °C, at pH 5. Read More

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December 2020