4,297 results match your criteria strain irradiation

Defect and strain engineering of monolayer WSe enables site-controlled single-photon emission up to 150 K.

Nat Commun 2021 Jun 11;12(1):3585. Epub 2021 Jun 11.

Department of Electrical and Computer Engineering, University of California, Santa Barbara, CA, USA.

In recent years, quantum-dot-like single-photon emitters in atomically thin van der Waals materials have become a promising platform for future on-chip scalable quantum light sources with unique advantages over existing technologies, notably the potential for site-specific engineering. However, the required cryogenic temperatures for the functionality of these sources has been an inhibitor of their full potential. Existing methods to create emitters in 2D materials face fundamental challenges in extending the working temperature while maintaining the emitter's fabrication yield and purity. Read More

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Photoinduced swing of a diarylethene thin broad sword shaped crystal: a study on the detailed mechanism.

Chem Sci 2020 Oct 26;11(45):12307-12315. Epub 2020 Oct 26.

Department of Materials Chemistry, Faculty of Science and Technology, Ryukoku University Seta Otsu Shiga 520-2194 Japan +81-77-543-7483 +81-77-543-7462.

We report a swinging motion of photochromic thin broad sword shaped crystals upon continuous irradiation with UV light. By contrast in thick crystals, photosalient phenomena were observed. The bending and swinging mechanisms are in fact due to molecular size changes as well as phase transitions. Read More

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October 2020

Breeding sake yeast and identification of mutation patterns by synchrotron light irradiation.

J Biosci Bioeng 2021 Jun 1. Epub 2021 Jun 1.

United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan; Faculty of Agriculture, Saga University, 1 Honjo-machi, Saga 840-8502, Japan. Electronic address:

Sake yeast is one of the important factors that characterize the aroma and taste of sake. To obtain sake yeast strains with different metabolic capabilities from other strains, breeding of a sake yeast is an effective way. In this study, sake yeast strain Y5201 was mutagenized by synchrotron light irradiation to obtain the mutant strains showing different brewing characteristics from parental strain Y5201, and comparative genome analysis between strain Y5201 and mutant strains was performed to identify mutation points and patterns induced by synchrotron light irradiation. Read More

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Radiation-Induced Senescence in p16+/LUC Mouse Lung Compared to Bone Marrow Multilineage Hematopoietic Progenitor Cells.

Radiat Res 2021 Jun 4. Epub 2021 Jun 4.

Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15232.

We defined the time course of ionizing radiation-induced senescence in lung compared to bone marrow of p16+/LUC mice in which the senescence-induced biomarker (p16) is linked to a luciferase reporter gene. Periodic in situ imaging revealed increased luciferase activity in the lungs of 20 Gy thoracic irradiated, but not 8 Gy total-body irradiated (TBI) mice beginning at day 75 and increasing to day 170. In serial sections of explanted lungs, senescent cells appeared in the same areas as did fibrosis in the 20 Gy thoracic irradiated, but not the 8 Gy TBI group. Read More

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Characterization and RNA-seq transcriptomic analysis of a Scenedesmus obliqnus mutant with enhanced photosynthesis efficiency and lipid productivity.

Sci Rep 2021 Jun 3;11(1):11795. Epub 2021 Jun 3.

Gansu Engineering Technology Research Center for Microalgae, Hexi University, Zhangye, 734000, People's Republic of China.

Microalgae have received significant attention as potential next-generation microbiologic cell factories for biofuels. However, the production of microalgal biofuels is not yet sufficiently cost-effective for commercial applications. To screen higher lipid-producing strains, heavy carbon ion beams are applied to induce a genetic mutant. Read More

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A Novel Genetic Sexing Strain of for Cost-Effective Sterile Insect Technique Applications: Improved Genetic Stability and Rearing Efficiency.

Insects 2021 May 27;12(6). Epub 2021 May 27.

Retired, USDA-APHIS-PPQ, Science and Technology, Raleigh, NC 27606, USA.

(Loew) is one of the most destructive insect pests damaging several fruits of economic importance. The sterile insect technique (SIT) is used under an area-wide integrated pest management approach, to suppress these pest populations. Mass rearing facilities were initially established to produce sterile males of bi-sexual strains in support of SIT. Read More

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Discovery of the Anticancer Drug Vinblastine from the Endophytic Alternaria alternata and Yield Improvement by Gamma Irradiation Mutagenesis.

J Appl Microbiol 2021 Jun 1. Epub 2021 Jun 1.

Plant Research Department, Nuclear Research Center, Egyptian Atomic Energy Authority, Cairo, Egypt.

Aims: Several fungal endophytes were isolated from some medicinal plants and screened for their ability to produce the anticancer drug vinblastine.

Methods And Results: An isolate was found to produce vinblastine (205.38 μg L ) and the identity of the fungal vinblastine was confirmed by UV-spectroscopic, HPLC, and ESI-MS analyses. Read More

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Tumor Treating Fields for Glioblastoma Therapy During the COVID-19 Pandemic.

Front Oncol 2021 7;11:679702. Epub 2021 May 7.

Division of Clinical Neurooncology, Department of Neurology and German Cancer Consortium (DKTK) Partner Site, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

Background: The COVID-19 pandemic has placed excessive strain on health care systems and is especially evident in treatment decision-making for cancer patients. Glioblastoma (GBM) patients are among the most vulnerable due to increased incidence in the elderly and the short survival time. A virtual meeting was convened on May 9, 2020 with a panel of neuro-oncology experts with experience using Tumor Treating Fields (TTFields). Read More

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Response of minimal operon to UVC and auto-aggregation: pilot study.

PeerJ 2021 12;9:e11197. Epub 2021 May 12.

Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovak Republic.

Aim: The study of minimal operon as a determinant of tellurium resistance (Te) is important for the purpose of confirming the relationship of these genes to the pathogenicity of microorganisms. The operon is widespread among bacterial species and pathogens, implicated also in phage inhibition, oxidative stress and colicin resistance. So far, there is no experimental evidence for the role of the minimal operon in ultraviolet C (UVC) resistance, biofilm formation and auto-aggregation. Read More

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The regulation of LexA on UV induced SOS response in based on transcriptome analysis.

J Microbiol Biotechnol 2021 May 24;31(6). Epub 2021 May 24.

State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266237, P. R. China.

SOS response is a conserved response to DNA damage in prokaryotes and negatively regulated by LexA protein which recognizes specifically a "SOS-box" motif present in the promoter region of SOS genes. DK1622 possess a gene, and the deletion had no significant effect on bacterial morphology, UV-C resistance, and sporulation, but delayed growth. UV-C radiation resulted in 651 up-regulated genes in , including the typical SOS genes , , , and so on, mostly enriched in the pathways of DNA replication and repair, secondary metabolism and signal transduction. Read More

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Influences of γ-ray irradiation on physico-chemical, structural, X-ray diffraction, thermal and antimicrobial activity of some γ-irradiated N',N'''-((Z)-ethane-1,2-diylidine)bis(2-aminobenzohydrazide) metal complexes.

Appl Radiat Isot 2021 Aug 13;174:109774. Epub 2021 May 13.

Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt.

A series of Co(II), Ni(II), Cu(II), Th(IV) and UO(II) complexes have been synthesized from reaction of nitrogen based ligand (L) i.e. N',N'''-((Z)-ethane-1,2-diylidine)bis(2-aminobenzohydrazide)(L) with their salts. Read More

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Echocardiography protocol for early detection of cardiac dysfunction in childhood cancer survivors in the multicenter DCCSS LATER 2 CARD study: Design, feasibility, and reproducibility.

Echocardiography 2021 May 20. Epub 2021 May 20.

Department of Pediatrics, Pediatric Cardiology Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Cardiotoxicity is a well-known side effect after anthracyclines and chest radiotherapy in childhood cancer survivors (CCS). The DCCSS LATER 2 CARD (cardiology) study includes evaluation of echocardiographic measurements for early identification of CCS at highest risk of developing heart failure. This paper describes the design, feasibility, and reproducibility of the echocardiography protocol. Read More

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"Don, doff, discard" to "don, doff, decontaminate"-FFR and mask integrity and inactivation of a SARS-CoV-2 surrogate and a norovirus following multiple vaporised hydrogen peroxide-, ultraviolet germicidal irradiation-, and dry heat decontaminations.

PLoS One 2021 19;16(5):e0251872. Epub 2021 May 19.

TERRA Research Centre, Gembloux Agro-Bio Tech, Liège University, Gembloux, Belgium.

Background: As the SARS-CoV-2 pandemic accelerates, the supply of personal protective equipment remains under strain. To combat shortages, re-use of surgical masks and filtering facepiece respirators has been recommended. Prior decontamination is paramount to the re-use of these typically single-use only items and, without compromising their integrity, must guarantee inactivation of SARS-CoV-2 and other contaminating pathogens. Read More

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Synonymous point mutation of gtfB gene caused by therapeutic X-rays exposure reduced the biofilm formation and cariogenic abilities of Streptococcus mutans.

Cell Biosci 2021 May 17;11(1):91. Epub 2021 May 17.

State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, 610041, China.

Background: The shift of oral microbiota is a critical factor of radiation caries in head and neck cancer patients after the radiotherapy. However, the direct effects of irradiation on the genome and virulence of cariogenic bacteria are poorly described. Here we investigated the genomic mutations and virulence change of Streptococcus mutans (S. Read More

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Photodynamic Therapy With Propolis: Antibacterial Effects on and Escherichia coli Analysed by Atomic Force Microscopy.

J Lasers Med Sci 2020 30;11(Suppl 1):S107-S112. Epub 2020 Dec 30.

Medical Professor at the Faculty of Human, Exact and Health Sciences of Piauí of the Institute of Higher Education of Vale do Parnaíba, Parnaíba, PI, Brazil.

Photodynamic therapy (PDT) is a process that uses a light source (e.g. laser), oxygen molecules and a photosensitizing agent. Read More

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December 2020

Radiation-Induced Lens Opacity and Cataractogenesis: A Lifetime Study Using Mice of Varying Genetic Backgrounds.

Radiat Res 2021 May 13. Epub 2021 May 13.

Public Health England, Centre for Radiation, Chemical and Environmental Hazards, Chilton, United Kingdom.

Recent epidemiological findings and reanalysis of historical data suggest lens opacities resulting from ionizing radiation exposures are likely induced at lower doses than previously thought. These observations have led to ICRP recommendations for a reduction in the occupational dose limits for the eye lens, as well as subsequent implementation in EU member states. The EU CONCERT LDLensRad project was initiated to further understand the effects of ionizing radiation on the lens and identify the mechanism(s) involved in radiation-induced cataract, as well as the impact of dose and dose-rate. Read More

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A Study on the Dissolution of the β-Precipitates in Zr-1Nb Alloy Under the Influence of Ne ion Irradiation.

Microscopy (Oxf) 2021 May 8. Epub 2021 May 8.

Homi Bhabha National Institute, Mumbai 400094, INDIA.

The stability of β-precipitates in the Zr-1Nb alloy has been studied under Ne ion irradiation of energy 250 keV by in-situ Transmission Electron Microscope (TEM) as a function of irradiation dose. The irradiation was carried out up to ~136 dpa at 573 K. Microstructural investigations have shown that up to ~38 dpa, precipitates showed an increase in size and for irradiation dose higher than 38 dpa, size of the precipitates was noticed to reduce. Read More

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A NIR laser induced self-healing PDMS/Gold nanoparticles conductive elastomer for wearable sensor.

J Colloid Interface Sci 2021 Oct 27;599:360-369. Epub 2021 Apr 27.

State Key Laboratory Base for Eco-Chemical Engineering, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

Self-healing conductive elastomers have been widely used in smart electronic devices, such as wearable sensors. However, nano fillers hinder the flow of polymer segments, which make the development of conductive elastomer with rapid repair and high ductility a challenge. In this work, thioctic acid (TA) was grafted onto amino-modified polysiloxane (PDMS-NH) by dehydration condensation of amino group and carboxyl group. Read More

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October 2021

Adjuvant breast cancer treatments cardiotoxicity and modern methods of detection and prevention of cardiac complications.

ESC Heart Fail 2021 May 5. Epub 2021 May 5.

Heart Failure Unit, Department of Cardiology and Congenital Diseases of Adults, Polish Mother's Memorial Hospital Research Institute (PMMHRI), Rzgowska 281/289, Lodz, 93-338, Poland.

The most common cancer diagnosis in female population is breast cancer, which affects every year about 2.0 million women worldwide. In recent years, significant progress has been made in oncological therapy, in systemic treatment, and in radiotherapy of breast cancer. Read More

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Photocross-Linked Antimicrobial Amino-Siloxane Elastomers.

ACS Appl Mater Interfaces 2021 May 4;13(19):22195-22203. Epub 2021 May 4.

Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.

Mechanically robust bulk antimicrobial polymers are one way to address disease transmission via contaminated surfaces. Here, we demonstrate the visible light photo-oxidative cross-linking of amine-containing PDMS using a single-component, solvent-free system where amines have a dual role as antimicrobial functionalities and cross-linking sites. Rose Bengal, a xanthene dye used as a fluorescent stain, is thermally reacted with the polymer to give a solvent-free liquid siloxane that can generate reactive singlet oxygen upon aerobic green light irradiation, coupling the amine functionalities into imine cross-links. Read More

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Swainsonine producing performance of Alternaria oxytropis was improved by heavy-ion mutagenesis technology.

FEMS Microbiol Lett 2021 May;368(8)

School of Pharmacy, Lanzhou University, West Donggang Road No. 199, Lanzhou 730000, PR China.

Swainsonine, an indolizidine alkaloid, is a promising anti-tumorigenic compound. Biological production of swainsonine was prospective, but the low swainsonine yield of wild type Alternaria oxytropis limited its production on a large scale. In present work, a stable A. Read More

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Establishment of a new and efficient Agrobacterium-mediated transformation system in the nematicidal fungus Purpureocillium lilacinum.

Microbiol Res 2021 Aug 26;249:126773. Epub 2021 Apr 26.

Department of Microbiology, Faculty of Biology, University of Science, Vietnam National University, Hanoi (VNU), 334 Nguyen Trai, Thanh Xuan, Hanoi, Viet Nam; Genomics Unit, National Key Laboratory of Enzyme and Protein Technology, University of Science, Vietnam National University, Hanoi (VNU), 334 Nguyen Trai, Thanh Xuan, Hanoi, Viet Nam. Electronic address:

Purpureocillium lilacinum (formerly Paecilomyces lilacinus) is widely commercialized for controlling plant-parasitic nematodes and represents a potential cell factory for enzyme production. This nematicidal fungus is intrinsically resistant to common antifungal agents used for genetic transformation. Therefore, molecular investigations in P. Read More

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Aloe-emodin-mediated antimicrobial photodynamic therapy against multidrug-resistant Acinetobacter baumannii: An in vivo study.

Photodiagnosis Photodyn Ther 2021 Apr 27;34:102311. Epub 2021 Apr 27.

Department of Pathogenic Microbiology & Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 West Yanta Road, Xi'an, 710061, PR China. Electronic address:

Background And Aim: Antimicrobial photodynamic therapy (aPDT) has shown great potential for treatment of superficial or localized multidrug-resistant (MDR) Acinetobacter baumannii infections. The purpose of this study was to investigate the cytotoxicity and in vivo safety of aloe-emodin (AE), and its photodynamic treatment efficacy against MDR A. baumannii infections. Read More

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Immune Responses to Irradiated Pneumococcal Whole Cell Vaccine.

Vaccines (Basel) 2021 Apr 19;9(4). Epub 2021 Apr 19.

Department of Oral Microbiology and Immunology and DRI, School of Dentistry, Seoul National University, Seoul 08826, Korea.

(pneumococcus) can cause respiratory and systemic diseases. Recently, γ-irradiation-inactivated, non-encapsulated, intranasal (r-SP) vaccine has been introduced as a novel serotype-independent and cost-effective vaccine. However, the immunogenic mechanism of r-SP is poorly understood. Read More

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High-throughput screening of multifunctional nanocoatings based on combinations of polyphenols and catecholamines.

Mater Today Bio 2021 Mar 10;10:100108. Epub 2021 Mar 10.

Institute of Biological and Chemical Systems - Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, 76344, Germany.

Biomimetic surface coatings based on plant polyphenols and catecholamines have been used broadly in a variety of applications. However, the lack of a rational cost-effective platform for screening these coatings and their properties limits the true potential of these functional materials to be unleashed. Here, we investigated the oxidation behavior and coating formation ability of a library consisting of 45 phenolic compounds and catecholamines. Read More

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Palliative Reconstructive Surgery for Advanced Maxillofacial Osteosarcoma in the Peak of COVID-19 Pandemic: A Matter of Ethical Decision-making.

Plast Reconstr Surg Glob Open 2021 Mar 29;9(3):e3545. Epub 2021 Mar 29.

Division of Plastic and Reconstructive Surgery, Oakland University William Beaumont School of Medicine, William Beaumont Hospital, Royal Oak, Mich.

The coronavirus disease 2019 posed an unprecedented strain to plastic surgery services. The scarcity of validated guidelines-at the beginning of this healthcare crisis-to direct clinical, ethical, transparent decision-making for head and neck cancer patients requiring palliative reconstructive surgery was a difficult situation. We report a 15-year-old girl with an advanced chemoresistant rare radiotherapy-induced mandibular osteosarcoma during the early phase of the pandemic in the United States in mid-March 2020, when official recommendations for triage were still developing. Read More

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First Report of Root Rot Caused by Calonectria montana on Sugar Beet in Heilongjiang Province, China.

Plant Dis 2021 Apr 27. Epub 2021 Apr 27.

Heilongjiang University, Xuefu Road 74, Harbin, Heilongjiang, China, 150080;

Sugar beet (Beta vulgaris L.) is an important crop that has significant economic value in northern regions of China, especially in Heilongjiang Province. In October 2019, root rot was discovered on the sugar beet cultivar HDW09 in Hulan (126°64' E, 46°00' N), Heilongjiang Province, China. Read More

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Light-driven continuous rotating Möbius strip actuators.

Nat Commun 2021 Apr 20;12(1):2334. Epub 2021 Apr 20.

Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, State Key Laboratory of Bioelectronics, School of Chemistry and Chemical Engineering, Southeast University, Nanjing, China.

Twisted toroidal ribbons such as the one-sided Möbius strip have inspired scientists, engineers and artists for many centuries. A physical Möbius strip exhibits interesting mechanical properties deriving from a tendency to redistribute the torsional strain away from the twist region. This leads to the interesting possibility of building topological actuators with continuous deformations. Read More

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In vitro and in vivo anti-Helicobacter pylori activity of selected medicinal plants employed for the management of gastrointestinal disorders.

Pak J Pharm Sci 2020 Nov;33(6(Supplementary)):2809-2814

Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University of Health Sciences, Jeddah, KSA.

Five medicinal plants Mentha piperita L., Trachyspermum ammi L., Viola odorata Linn. Read More

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November 2020

Thermodynamic driving forces of guest confinement in a photoswitchable cage.

Phys Chem Chem Phys 2021 Mar 23;23(12):7321-7332. Epub 2021 Mar 23.

Theoretical Chemistry, Ruhr-University Bochum, D-44780 Bochum, Germany.

Photoswitchable cages that confine small guest molecules inside their cavities offer a way to control the binding/unbinding process through irradiation with light of different wavelengths. However, detailed characterization of the structural and thermodynamic consequences of photoswitching is very challenging to achieve by experiments alone. Thus, all-atom molecular dynamics (MD) simulations were carried out to gain insight into the relationship between the structure and binding affinity. Read More

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