Epilepsy Res 2021 Nov 20;178:106819. Epub 2021 Nov 20.
Université Paris-Saclay, CEA, CNRS, Inserm, Biomaps, Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, 91401 ORSAY France; Department of Neurosurgery, Epilepsy Unit, Groupe Hospitalier Universitaire Psychiatrie et Neurosciences, Sainte-Anne Hospital, 1 rue Cabanis, 75014 Paris, France. Electronic address:
Purpose: Hybrid PET/MR is a promising tool in focal drug-resistant epilepsy, however the additional value for the detection of epileptogenic lesions and surgical decision-making remains to be established.
Methods: We retrospectively compared F-FDG PET/MR images with those obtained by a previous F-FDG PET co-registered with MRI (PET+MR) in 25 consecutive patients (16 females, 13-60 years) investigated for focal drug-resistant epilepsy. Visual analysis was performed by two readers blinded from imaging modalities, asked to assess the technical characteristics (co-registration, quality of images), the confidence in results, the location of PET abnormalities and the presence of a structural lesion on MRI. Read More