98,414 results match your criteria statistical difference


An intelligent method based on feed-forward artificial neural network and least square support vector machine for the simultaneous spectrophotometric estimation of anti hepatitis C virus drugs in pharmaceutical formulation and biological fluid.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jul 22;263:120190. Epub 2021 Jul 22.

Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran.

This study proposed simple and reliable spectrophotometry method for simultaneous analysis of hepatitis C antiviral binary mixture containing sofosbuvir (SOF) and daclatasvir (DAC). This technique is based on the use of feed-forward artificial neural network (FF-ANN) and least square support vector machine (LS-SVM). FF-NN with Levenberg-Marquardt (LM) and Cartesian genetic programming (CGP) algorithms was trained to determine the best number of hidden layers and the number of neurons. Read More

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Comparison of Nasopharyngeal Swab and Nasopharyngeal Aspiration in Adults for SARS-CoV-2 Identification Using Reverse Transcription Polymerase Chain Reaction.

J Med Virol 2021 Jul 31. Epub 2021 Jul 31.

Koç University School of Medicine, Department of Otolaryngology.

Objective: To compare RT-PCR results of nasopharyngeal aspiration (NA) and nasopharyngeal swab (NS) samples in the diagnosis of COVID-19.

Methods: NS was obtained with a dacron swab and NA was performed by aspiration cannula. The sampling was performed by an otolaryngologist to ensure standardized correct sampling from the nasopharynx. Read More

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Optimisation of CT protocols in PET-CT across different scanner models using different automatic exposure control methods and iterative reconstruction algorithms.

EJNMMI Phys 2021 Jul 31;8(1):58. Epub 2021 Jul 31.

King's College London & Guy's and St Thomas' PET Centre, School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.

Background: A significant proportion of the radiation dose from a PET-CT examination is dependent on the CT protocol, which should be optimised for clinical purposes. Matching protocols on different scanners within an imaging centre is important for the consistency of image quality and dose. This paper describes our experience translating low-dose CT protocols between scanner models utilising different automatic exposure control (AEC) methods and reconstruction algorithms. Read More

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Comparison of marginal and internal fit of three-unit implant-supported fixed prosthetic substructures fabricated using CAD/CAM systems.

Clin Oral Investig 2021 Jul 31. Epub 2021 Jul 31.

Department of Prosthodontics, Faculty of Dentistry, Recep Tayyip Erdogan University, Rize, Turkey.

Objective: This study compared the marginal and internal fit of implant-supported fixed dentures fabricated using CAD/CAM systems.

Materials And Methods: A lower jaw model representing partial edentulism was produced. Two dental implants were inserted in the area of teeth 35 and 37, onto which cemented abutments were screwed. Read More

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Three-dimensional bladder ultrasound to measure daily urinary bladder volume in hospitalized dogs.

J Vet Intern Med 2021 Jul 31. Epub 2021 Jul 31.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.

Background: Urinary bladder volume (UBV) and urine residual volume (URV) provide important information for hospitalized dogs and might allow recognition of urine retention.

Objective: Using 3-dimensional (3D) ultrasound to monitor daily URV is a safe and effective way to recognize urinary retention.

Animals: Twenty-five client-owned hospitalized dogs. Read More

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Chest x-ray resolution after SARS-CoV-2 infection.

Med Glas (Zenica) 2021 Aug 1;18(2). Epub 2021 Aug 1.

General Hospital Tešanj, Tešanj, Bosnia and Herzegovina.

Aim To analyse the resolution of chest X-ray findings in relation to laboratory parameters in patients infected with acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a two- month followup. Analysis of chest X-ray findings in the first few months after the disease is the main goal of our work. Methods Out of the total of 343 patients chest X-ray findings were followed in 269 patients. Read More

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Brain-dead and coma patients exhibit different serum metabolic profiles: preliminary investigation of a novel diagnostic approach in neurocritical care.

Sci Rep 2021 Jul 30;11(1):15519. Epub 2021 Jul 30.

Department of Biochemistry, Molecular Biology and Biotechnology, Faculty of Chemistry, Wroclaw University of Science and Technology, Norwida 4/6, 50-373, Wroclaw, Poland.

There is a clear difference between severe brain damage and brain death. However, in clinical practice, the differentiation of these states can be challenging. Currently, there are no laboratory tools that facilitate brain death diagnosis. Read More

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Low vitamin D levels and increased neutrophil in patients admitted at ICU with COVID-19.

Clin Nutr ESPEN 2021 Aug 31;44:466-468. Epub 2021 May 31.

Clinical Nutrition, Geneva University Hospital, Geneva, Switzerland.

Background & Aims: Systemic inflammation has been reported as a new predictor for COVID-19 outcomes. Thus, we hypothesized that ICU patients infected by COVID-19 had lower blood vitamin D levels and increased systemic inflammation. Therefore, this is the first Brazilian study to evaluate the vitamin D concentrations and NLR as a systemic inflammation in patients infected by COVID-19 admitted in ICU. Read More

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Association between phase angle and height-to-age index classifications of children under five years of age.

Clin Nutr ESPEN 2021 Aug 26;44:367-371. Epub 2021 May 26.

Faculdade de Nutrição, Universidade Federal de Alagoas, Maceió, Alagoas, 57072-970, Brazil. Electronic address:

Background & Aims: The phase angle (PA) has been used as an indicator of prognosis and nutritional status because it reflects the integrity of the individuals' cellular function. In contrast to the investigations that assessed acute malnutrition (weight deficit) and PA in children, studies that evaluated the relationship of this indicator with stunting (height deficit) are still scarce and inconclusive. Thus, we aim to investigate whether there are differences in PA according to the classifications of the height-for-age (H/A) index of children under five years of age. Read More

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Correlation between vitamin D deficiency and fasting blood glucose levels in obese children.

Clin Nutr ESPEN 2021 Aug 2;44:200-203. Epub 2021 Jul 2.

Department of Pediatrics, Hasanuddin University's Faculty of Medicine, Makassar, 90245, Indonesia.

Background: This study aimed to determine the relationship between Deficiency of vitamin D and hyperglycemia in children with obesity.

Methods: This cross-sectional study was carried out between February and April of 2020. This study's subject population consisted of high school students aged 11 to 17 who were obese. Read More

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Left subclavian artery revascularization in thoracic endovascular aortic repair: single center's clinical experiences from 171 patients.

J Cardiothorac Surg 2021 Jul 30;16(1):207. Epub 2021 Jul 30.

Department of Cardiothoracic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210000, Jiangsu, People's Republic of China.

Background: Left subclavian artery revascularization (LSA) is frequently performed in the setting of thoracic endovascular repair (TEVAR). The purpose of this study was to compare different techniques for LSA revascularization during TEVAR.

Methods: We performed a single center's retrospective cohort study from 2016 to 2019. Read More

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The use of Web-based interactive technology to promote HPV vaccine uptake among young females: a randomized controlled trial.

Authors:
Qi Wang Wen Zhang

BMC Womens Health 2021 Jul 30;21(1):277. Epub 2021 Jul 30.

School of Journalism and Culture Communication, Zhongnan University of Economics and Law, 182 Nanhu Avenue, Wuhan, 430073, People's Republic of China.

Background: Currently no study has investigated whether Web-based interactive technology can influence females to adopt healthy behaviors. We investigated how and under what conditions do Web-based interactivity influence vaccination intentions among young females.

Methods: In this randomized controlled trail, we conduct a 2 (mode of information presentation: narrative vs. Read More

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Comparison of the novel VieScope with conventional and video laryngoscope in a difficult airway scenario - a randomized, controlled simulation trial.

BMC Emerg Med 2021 Jul 30;21(1):90. Epub 2021 Jul 30.

University of Cologne, Medical Faculty, and University Hospital Cologne, Department of Anaesthesiology and Intensive Care Medicine, Kerpener Str. 62, 50937, Cologne, Germany.

Background: Endotracheal intubation continues to be the gold standard for securing the airway in emergency situations. Difficult intubation is still a dreadful situation when securing the airway.

Objective: To compare VieScope with Glidescope and conventional Macintosh laryngoscopy (MAC) in a simulated difficult airway situation. Read More

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A Novel Use of Retinoscopy for the Evaluation of Binocular Balance of Spherical Refractive Errors.

Semin Ophthalmol 2021 Jul 30:1-5. Epub 2021 Jul 30.

Department of Ophthalmology, Istanbul Medeniyet University School of Medicine, Goztepe Education and Research Hospital, Istanbul, Turkey.

Purpose: Binocular balancing is an important component of refractive correction to avoid asthenopic complaints. Polaroid filters are commonly used for binocular balancing; they rely on subjective examination and cannot represent daily visual activities. We describe a new examination approach to evaluate binocular balance with retinoscopy, which is an objective examination method and does not require strict patient cooperation. Read More

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Serological prevalence and risk factors of Toxoplasma gondii in Zoo Mammals in Chile.

Prev Vet Med 2021 Jul 24;194:105445. Epub 2021 Jul 24.

Laboratory of Parasitology and Parasitic Diseases, Department of Preventive Veterinary Medicine, Faculty of Veterinary Medicine and Livestock Sciences, Universidad de Chile, Santa Rosa 11.735, La Pintana, Santiago, Chile. Electronic address:

Toxoplasma gondii is a zoonotic cosmopolitan protozoan that causes a high mortality rate among zoo mammals such as New World primates, meerkats, marsupials and Pallas' cat. It has been recently reported in Chile, mainly among wild populations, but also as the cause of death of a kangaroo and a mara. However, there has not been a T. Read More

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Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.

Lancet Respir Med 2021 Jul 27. Epub 2021 Jul 27.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: Doxycycline is often used for treating COVID-19 respiratory symptoms in the community despite an absence of evidence from clinical trials to support its use. We aimed to assess the efficacy of doxycycline to treat suspected COVID-19 in the community among people at high risk of adverse outcomes.

Methods: We did a national, open-label, multi-arm, adaptive platform randomised trial of interventions against COVID-19 in older people (PRINCIPLE) across primary care centres in the UK. Read More

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Secondary aerosol formation from a Chinese gasoline vehicle: Impacts of fuel (E10, gasoline) and driving conditions (idling, cruising).

Sci Total Environ 2021 Jul 6;795:148809. Epub 2021 Jul 6.

State Key Joint Laboratory of Environmental Simulation and Pollution Control, International Joint Laboratory for Regional Pollution Control, Ministry of Education (IJRC), College of Environmental Sciences and Engineering, Peking University, Beijing 100871, PR China; Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, PR China.

Chassis dynamometer experiments were conducted to investigate the effect of vehicle speed and usage of ethanol-blended gasoline (E10) on formation and evolution of gasoline vehicular secondary organic aerosol (SOA) using a Gothenburg Potential Aerosol Mass (Go: PAM) reactor. The SOA forms rapidly, and its concentration exceeds that of primary organic aerosol (POA) at an equivalent photochemical age (EPA) of ~1 day. The particle effective densities grow from 0. Read More

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Quality Assurance for Small-Field VMAT SRS and Conventional-Field IMRT Using the Exradin W1 Scintillator.

Technol Cancer Res Treat 2021 Jan-Dec;20:15330338211036542

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.

Background: Plastic scintillator detector (PSD) Exradin W1 has shown promising performance in small field dosimetry due to its water equivalence and small sensitive volume. However, few studies reported its capability in measuring fields of conventional sizes. Therefore, the purpose of this study is to assess the performance of W1 in measuring point dose of both conventional IMRT plans and VMAT SRS plans. Read More

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Regression models for order-of-addition experiments.

Biom J 2021 Jul 29. Epub 2021 Jul 29.

Statistical Consulting Unit, Australian National University, Canberra, ACT 2600, Australia.

The purpose of order-of-addition (OofA) experiments is to identify the best order in a sequence of m components in a system. Such experiments may be analyzed by various regression models, the most popular ones being based on pairwise ordering (PWO) factors or on component-position (CP) factors. This paper reviews these models and extensions and proposes a new class of models based on response surface (RS) regression using component position numbers as predictor variables. Read More

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Evaluation of the NIO and T.A.L.O.N Intraosseous Devices as Placed by U.S. Army Conventional Force Combat Medics-A Randomized Crossover Study.

Mil Med 2021 Jul 30. Epub 2021 Jul 30.

Carl R. Darnall Army Medical Center, Fort Hood, TX 76544, USA.

Introduction: In recent U.S. Military conflicts, hemorrhage remains the leading cause of preventable death with 30%-40% mortality rates. Read More

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Association of incremental pulse wave velocity with cardiometabolic risk factors.

Sci Rep 2021 Jul 29;11(1):15413. Epub 2021 Jul 29.

Department of Electrical Engineering, Indian Institute of Technology Madras, Chennai, 600036, India.

We investigate the association of incremental pulse wave velocity (ΔC; the change in pulse wave velocity over a cardiac cycle) with cardiometabolic risk factors and report the first and (currently) the largest population-level data. In a cross-sectional study performed in a cohort of 1373 general population participants, ΔC was measured using clinically validated ARTSENS devices. There were 455 participants in the metabolic syndrome (MetS) group whose average ΔC was ~ 28. Read More

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Effectiveness of a Cloud-Based Telepathology System in China: Large-Sample Observational Study.

J Med Internet Res 2021 Jul 29;23(7):e23799. Epub 2021 Jul 29.

National Telemedicine Center of China, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Background: Whole-slide imaging allows the entire slide to be viewed in a manner that simulates microscopy; therefore, it is widely used in telepathology. However, managing the large digital files needed for whole-slide imaging is difficult. To solve this problem, we set up the Chinese National Cloud-Based Telepathology System (CNCTPS). Read More

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Are Hindfoot Procedures More Painful Than Forefoot?-A Prospective, Observational Study in Elective Foot and Ankle Surgery.

J Foot Ankle Surg 2021 Jun 11. Epub 2021 Jun 11.

Academic Team of Musculoskeletal Surgery (AToMS) Leicester General Hospital, Leicester, UK.

Pain after lower limb orthopedic surgery can be severe. Poorly controlled pain is associated with adverse outcomes. Peripheral nerve blocks (PNB) have become popular in foot and ankle surgery for their effective pain control and low complication rates. Read More

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Ethnic variation in medial orbital wall anatomy and its implications for decompression surgery.

BMC Ophthalmol 2021 Jul 29;21(1):290. Epub 2021 Jul 29.

Singapore National Eye Centre, Singapore, Singapore.

Background: To describe the inter-ethnic variation in medial orbital wall anatomy between Chinese, Malay, Indian and Caucasian subjects.

Methods: Single-centre, retrospective, Computed Tomography (CT)-based observational study. 20 subjects of each ethnicity, were matched for gender and laterality. Read More

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Combined Effect of MTHFR C677T and PAI-1 4G/5G Polymorphisms on the Risk of Venous Thromboembolism in Chinese Lung Cancer Patients.

Clin Appl Thromb Hemost 2021 Jan-Dec;27:10760296211031291

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.

Venous thromboembolism (VTE) is a common and potentially fatal complication in cancer patients. Although several genetic risk factors related to thrombophilia have been identified, their contributions for the occurrence of VTE in cancer patients have conflicting results. The aim of this study was to evaluated the gene polymorphisms of methylenetetrahydrofolate reductase (MTHFR) C677T and plasminogen activator inhibitor-1 (PAI-1) 4G/5G in lung cancer patients, with and without VTE, and the combined effect on the risk of VTE. Read More

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Cardiac Output Measurement in Neonates and Children Using Noninvasive Electrical Bioimpedance Compared With Standard Methods: A Systematic Review and Meta-Analysis.

Crit Care Med 2021 Jul 29. Epub 2021 Jul 29.

Biomedical Research Centre, Imperial College London, London, United Kingdom. Department of Neonatology, Imperial College Healthcare NHS Trust, London, United Kingdom. Library Services, Imperial College London, London, United Kingdom. Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom. Centre for Paediatrics and Child Health, Imperial College London, London, United Kingdom.

Objective: To systematically review and meta-analyze the validity of electrical bioimpedance-based noninvasive cardiac output monitoring in pediatrics compared with standard methods such as thermodilution and echocardiography.

Data Sources: Systematic searches were conducted in MEDLINE and EMBASE (2000-2019).

Study Selection: Method-comparison studies of transthoracic electrical velocimetry or whole body electrical bioimpedance versus standard cardiac output monitoring methods in children (0-18 yr old) were included. Read More

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A Cross-Sectional Evaluation of Outcomes of Pediatric Thyroglossal Duct Cyst Excision.

ORL J Otorhinolaryngol Relat Spec 2021 Jul 29:1-8. Epub 2021 Jul 29.

Pediatric Otolaryngology, Lehigh Valley Health Children's Hospital, Allentown, Pennsylvania, USA.

Introduction: Thyroglossal duct cysts (TGDCs) are the most common form of congenital neck cysts. They may become infected causing dysphagia or respiratory distress. Accordingly, the treatment is always surgical removal. Read More

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Admission Hemoglobin Is Prognostic for In-Hospital Mortality in Oldest-Old Patients with Acute Ischemic Stroke.

Gerontology 2021 Jul 29:1-8. Epub 2021 Jul 29.

Department of Neurology, Taikang Xianlin Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.

Introduction: Anemia is a common condition encountered in acute ischemic stroke, and only a few pieces of evidence has been produced suggesting its possible association with short-term mortality have been produced. The study sought to assess whether admission anemia status had any impact on short-term clinical outcome among oldest-old patients with acute ischemic stroke.

Materials And Methods: A retrospective review of Electronic Medical Recording System was performed in 2 tertiary hospitals. Read More

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Angioplasty alone versus acute stenting for acute tandem occlusions due to internal carotid artery atherosclerotic.

Clin Neurol Neurosurg 2021 Jul 10;208:106818. Epub 2021 Jul 10.

Department of Neurology, First Affiliated Hospital, Hainan Medical University, Haikou, Hainan, China. Electronic address:

Objective: The aim of the study is to compare the efficacy and safety of angioplasty alone with acute stenting for acute tandem occlusions (TO) due to internal carotid artery atherosclerotic.

Methods: We identified 112 patients who underwent an endovascular treatment (EVT) for acute tandem internal carotid artery occlusions from the prospectively maintained registries 5 comprehensive stroke centers. The study cohort included 75 patients with underlying atherosclerotic lesion of the extracranial internal carotid artery, forty-five in the balloon angioplasty (BA) alone group and 30 in the acute stenting (AS) group. Read More

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An untargeted metabolomics approach to identify markers to distinguish duck eggs that come from different poultry breeding systems by ultra high performance liquid chromatography-high resolution mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2021 Jul 3;1179:122820. Epub 2021 Jul 3.

Institute of Food Safety, Chinese Academy of Inspection & Quarantine, Beijing 100176, China. Electronic address:

Untargeted metabolomics approach based on ultra high performance liquid chromatography coupled with high resolution mass spectrometry (UHPLC-HRMS) was used to investigate the differences in cage duck eggs and sea duck eggs that from different poultry breeding system, which could help to combat fraud within the egg industry. High dimensions and complex data collected by UHPLC-HRMS were analyzed by multivariate statistical analysis. Identification model of sea duck eggs based on was established. Read More

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