Crit Pathw Cardiol 2021 May 12. Epub 2021 May 12.
Heart and Vascular Institute, Henry Ford Health System, Detroit, MI, USA Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI, USA Depar Medizinische Klinik III, Universitätsklinikum Heidelberg, Heidelberg, Germany Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA Department of Medicine, Inova Heart and Vascular Institute, Falls Church, VA, USA Department of Medical Sciences and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden Department of Emergency Medicine, Cantonal Hospital Lucerne, Switzerland Manchester University NHS Foundation Trust, Manchester, United Kingdom Division of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom Department of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Switzerland.
Background: Although the recommended cut-point for cardiac troponin (cTn) is the 99th percentile, many institutions use cut-points that are multiples higher than the 99th percentile for diagnosing acute myocardial infarction (AMI). Prior studies have shown that patients with a HEART score (HS) ≤ 3 and normal serial cTn values (modified HS) are at low risk for adverse events. This study aimed to evaluate the prognostic utility of the HS when various cTn cut-points are used. Read More