11,595 results match your criteria stable angina


Levels and clinical significance of serum homocysteine (Hcy), high-density lipoprotein cholesterol (HDL-C), vaspin, and visfatin in elderly patients with different types of coronary heart disease.

Ann Palliat Med 2021 May;10(5):5679-5686

Department of Geriatric ICU, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences, Sichuan Translational Medicine Research Hospital, Chengdu, China.

Background: To investigate the levels and clinical significance of serum homocysteine (Hcy), high-density lipoprotein cholesterol (HDL-C), visceral adipose tissue-derived serine protease inhibitor (vaspin), and visceral fat-specific adipokine (visfatin) in elderly patients with different types of coronary heart disease (CHD).

Methods: A total of 208 elderly patients with CHD admitted to our hospital were selected as the observation group, and 57 healthy volunteers who received physical examinations during the same period were selected as the healthy control group. The patients in the observation group were divided into a stable angina pectoris (SAP) group, an unstable angina pectoris (UAP) group, and an acute myocardial infarction (AMI) group according to their clinical diagnosis. Read More

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Gender characteristics of lipid profile parameters and markers of vascular inflammation in patients with stable angina pectoris in groups with presence and absence of type 2 diabetes.

Klin Lab Diagn 2021 Jun;66(6):325-332

Tyumen Cardiology Research Center, Tomsk National Research Medical Center RAS.

The study of the parameters of the lipid profile and markers of the inflammatory reaction of the vascular wall in patients with stable angina pectoris in the presence or absence of type 2 diabetes mellitus (T2DM) is of great importance for revealing the gender characteristics of the pathophysiological mechanisms of the development and course of diseases, developing secondary prevention of complications and determining the prognosis. 194 patients with stable angina pectoris (SA), single-vessel coronary artery disease, mean age 60.3 ± 7. Read More

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Prevalence of Angina Among Primary Care Patients With Coronary Artery Disease.

JAMA Netw Open 2021 Jun 1;4(6):e2112800. Epub 2021 Jun 1.

Harvard Medical School, Boston, Massachusetts.

Importance: Angina pectoris is associated with morbidity and mortality. Angina prevalence and frequency among contemporary US populations with coronary artery disease (CAD) remain incompletely defined.

Objective: To ascertain the angina prevalence and frequency among stable outpatients with CAD. Read More

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The comparison of IL-17 levels in patients with unstable angina before and after medical treatment.

Hum Antibodies 2021 Jun 5. Epub 2021 Jun 5.

Zahedan University of Medical Sciences, Zahedan, Iran.

Background: Interleukin (IL)-17 plays a central role in orchestrating the cytokine cascade and accelerates atherosclerosis and plaque vulnerability in animal models. However, epidemiological data evaluating the role of IL-17 levels in unstable angina are lacking. The aim of our study is to evaluate and compare the IL-17 levels in unstable angina (UA) cases before and after treatment. Read More

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PRospective Observational registry evaluating the Safety and Effectiveness of Orsiro Stent in Chilean patients - ROSES registry.

Cardiovasc Revasc Med 2021 May 27. Epub 2021 May 27.

San Borja Arriarán Hospital & University of Chile, Santiago, Chile. Electronic address:

Background: There is little information of the performance of the new generation of stents with bioabsorbable polymers in the Latin-American population. This registry aimed to further validate the safety and efficacy of the Orsiro bioresorbable polymer sirolimus-eluting stent (BPSES) in unselected patients undergoing percutaneous coronary intervention (PCI) in Chilean centers.

Methods: We prospectively enrolled patients undergoing PCI with BPSES in 6 Chilean centers. Read More

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Estimating the Real-World Performance of the PROMISE Minimal-Risk Tool: Nanna et al.: PROMISE Risk Score.

Am Heart J 2021 May 30. Epub 2021 May 30.

Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.

Background: Stable chest pain is a common indication for cardiac catheterization. We assessed the prognostic value of the PROMISE Minimal-Risk Tool in identifying patients who are at very low risk of obstructive coronary artery disease or downstream cardiovascular adverse outcomes.

Methods: We applied the PROMISE Minimal-Risk Tool to consecutive patients without known CAD who underwent elective cardiac catheterization for stable angina from January 1, 2000 to December 31, 2014 in the Duke Databank for Cardiovascular Disease (DDCD). Read More

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Association Between Serum Elabela Levels and Chronic Totally Occlusion in Patients with Stable Angina Pectoris.

Arq Bras Cardiol 2021 May 31. Epub 2021 May 31.

Gaziantep University Medicine Faculty, Departamento de Cardiologia, Gaziantep - Turquia.

Background: The beneficial effects of Elabela on the cardiovascular system have been shown in studies.

Objective: To compare serum Elabela levels of chronic total occlusion (CTO) patients with control patients with normal coronary arteries, and to investigate whether there is a correlation with collateral development.

Methods: The study was planned cross-sectionally and prospectively. Read More

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Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris.

Front Nutr 2021 14;8:676026. Epub 2021 May 14.

Centre for Nutrition, Department of Clinical Science, University of Bergen, Bergen, Norway.

Choline is an essential nutrient involved in a wide range of physiological functions. It occurs in water- and lipid-soluble forms in the body and diet. Foods with a known high choline content are eggs, beef, chicken, milk, fish, and selected plant foods. Read More

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[Meta-analysis of efficacy and safety of Shexiang Tongxin Dripping Pills combined with conventional therapy of coronary heart disease].

Zhongguo Zhong Yao Za Zhi 2021 May;46(9):2325-2332

School of Management, Beijing University of Chinese Medicine Beijing 100029, China.

The aim of the research was to evaluate the efficacy and safety associated with Shexiang Tongxin Dropping Pills combined with conventional therapy for patients with coronary heart disease(CHD). We searched 8 electronic databases up to November 2020, including PubMed, Cochrane Library, EMbase, Web of Science, CNKI, Wanfang, VIP and SinoMed. Eligible studies were clinical trials of Shexiang Tongxin Dropping Pills combined with conventional therapy used in the treatment of coronary heart disease(CHD). Read More

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The Priority of Non-HDL-C Assessment to Predict New Lesions among Stable Angina Patients with Strong Statins.

J Atheroscler Thromb 2021 May 25. Epub 2021 May 25.

Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University.

Aim: In this study, we aim to examine the clinical meaning of low-density lipoprotein cholesterol (LDL-C) <70 mg/dL as assessed by Friedewald equation [LDL-C (F)] and Martin method [LDL-C (M)] and non-high-density lipoprotein cholesterol (HDL-C) <100 mg/dL on the occurrence of new lesions among Japanese patients with stable angina who underwent percutaneous coronary intervention (PCI) and were prescribed with strong statins.

Methods: Among the 537 consecutive stable angina patients who had underwent PCI and had been prescribed with strong statins, the association between the occurrence of new lesions with myocardial ischemia at the 9-month follow-up coronary angiography and ≤ 2 years after PCI and baseline characteristics were assessed.

Results: New lesions appeared 9 months and ≤ 2 years after PCI in 31 and 90 patients, respectively. Read More

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Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group.

Eur Heart J 2021 May 26. Epub 2021 May 26.

Department of Cardiology, Cedars-Sinai Medical Center, Barbra Streisand Women's Heart Center, Smidt Heart Institute, Los Angeles, CA, USA.

Aims: To provide multi-national, multi-ethnic data on the clinical characteristics and prognosis of patients with microvascular angina (MVA).

Methods And Results: The Coronary Vasomotor Disorders International Study Group proposed the diagnostic criteria for MVA. We prospectively evaluated the clinical characteristics of patients according to these criteria and their prognosis. Read More

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Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain.

Circ Genom Precis Med 2021 May 25. Epub 2021 May 25.

Department of Biomedicine, Aarhus University, Aarhus & Department of Health Science and Technology, Aalborg University, Aalborg & Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.

- Polygenic risk scores (PRSs) are associated with coronary artery disease (CAD), but the clinical potential of using PRSs at the single-patient level for risk stratification has yet to be established. We investigated whether adding a PRS to clinical risk factors (CRFs) improves risk stratification in patients referred to coronary computed tomography angiography (CTA) on a suspicion of obstructive CAD. - In this prespecified diagnostic substudy of the Dan-NICAD trial we included 1617 consecutive patients with stable chest symptoms and no prior history of CAD referred for coronary CTA. Read More

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Machine Learning Identifies Metabolic Signatures that Predict the Risk of Recurrent Angina in Remitted Patients after Percutaneous Coronary Intervention: A Multicenter Prospective Cohort Study.

Adv Sci (Weinh) 2021 05 8;8(10):2003893. Epub 2021 Mar 8.

School of Medicine University of California San Diego CA 92093 USA.

Recurrent angina (RA) after percutaneous coronary intervention (PCI) has few known risk factors, hampering the identification of high-risk populations. In this multicenter study, plasma samples are collected from patients with stable angina after PCI, and these patients are followed-up for 9 months for angina recurrence. Broad-spectrum metabolomic profiling with LC-MS/MS followed by multiple machine learning algorithms is conducted to identify the metabolic signatures associated with future risk of angina recurrence in two large cohorts ( = 750 for discovery set, and = 775 for additional independent discovery cohort). Read More

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Medical and Revascularization Management of Stable Ischemic Heart Disease: An Overview.

Int J Angiol 2021 Mar 21;30(1):83-90. Epub 2021 Jan 21.

Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Stable ischemic heart disease (SIHD) affects approximately 10 million Americans with 500,000 new cases diagnosed each year. Patients with SIHD are primarily managed in the outpatient setting with aggressive cardiovascular risk factor modification via medical therapy and lifestyle changes. Currently, this approach is considered as the mainstay of treatment. Read More

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Predictive nursing helps improve treatment efficacy, treatment compliance, and quality of life in unstable angina pectoris patients.

Am J Transl Res 2021 15;13(4):3473-3479. Epub 2021 Apr 15.

The Second District of Comprehensive Internal Medicine, South Hospital of Chenzhou First People's Hospital Chenzhou 423000, Hunan Province, China.

Objective: This paper aims to explore the effects of predictive nursing on the treatment efficacy in unstable angina pectoris (UAP) patients and on their treatment compliance and quality of life (QOL).

Methods: Admitted to our hospital from November 2017 to August 2019, 110 UAP patients were recruited as the study cohort and randomized into a control group (CG) and an observation group (OG). Among them, 53 patients in the CG underwent routine nursing, and the remaining 57 patients in the OG underwent additional predictive nursing in addition to the routine nursing. Read More

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The feasibility of using Hcy, CRP, and Cys-C to analyze AMI patients' disease conditions and prognoses.

Am J Transl Res 2021 15;13(4):2724-2730. Epub 2021 Apr 15.

Department of Cardiology, Affiliated Hospital of Chengde Medical University Chengde City, Hebei Province, China.

Objective: This study was conducted to investigate the feasibility of using the serum homocysteine (Hcy), C-reactive protein (CRP), and cystatin C (Cys-C) levels to evaluate the conditions and prognoses of acute myocardial infarction (AMI) patients.

Methods: One hundred and twenty patients with AMI were enrolled as an observation group (the AMI group). Eighty patients with stable angina pectoris were included in a control group (the SA group). Read More

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Acupuncture as Adjuvant Therapy for Treating Stable Angina Pectoris with Moderate Coronary Artery Lesions and the Mechanism of Heart-Brain Interactions: A Randomized Controlled Trial Protocol.

Evid Based Complement Alternat Med 2021 28;2021:6634404. Epub 2021 Apr 28.

School of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.

. Stable angina pectoris with moderate coronary artery lesions is a syndrome caused by coronary artery stenosis, which endangers the quality of life. Previous acupuncture studies have shown effectiveness as a complementary therapy for ischaemic heart disease. Read More

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Colchicine to Prevent Periprocedural Myocardial Injury in Percutaneous Coronary Intervention: The COPE-PCI Pilot Trial.

Circ Cardiovasc Interv 2021 May 18;14(5):e009992. Epub 2021 May 18.

Peninsula Heart Service, Peninsula Health, Frankston, Australia (J.C., N.H., R.L., M.F., J.L.).

[Figure: see text]. Read More

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Lack of association between serum IL-25 levels and acute coronary syndrome: a preliminary study.

Kardiologiia 2021 May 3;61(4):60-65. Epub 2021 May 3.

Department of Biochemistry, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Purpose    Here, for the first time, the possible association between IL-25 and the risk of acute coronary syndrome (ACS) in Iranian patients was investigated.Material and methods    In this study, serum IL-25 concentrations were measured with an enzyme-linked immunosorbent assay in 88 ACS patients, 40 stable angina pectoris (SAP) patients, and 50 healthy control subjects.Results    No significant differences in IL-25 concentrations were observed between SAP (340±168 ng / l), ACS (330±151 ng / l), and control (302±135 ng / l) groups (p=0. Read More

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Predictors of Obstructive Sleep Apnoea (OSA) Population in the Coronary Angiogram Database of South Australia (CADOSA).

Curr Probl Cardiol 2021 Mar 20:100846. Epub 2021 Mar 20.

Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia; Department of Cardiology, Central Adelaide Local Health Network, Adelaide, Australia; Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, Australia. Electronic address:

Obstructive sleep apnoea (OSA) is increasingly recognized to be a risk factor for cardiovascular disease. This study assessed the prevalence and clinical predictors of OSA in patients undergoing coronary angiography. Consecutive patients undergoing coronary angiography in South Australian public hospitals from 2015 to 2018 were included. Read More

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Optical coherence tomography and coronary angioscopy assessment of healed coronary plaque components.

Int J Cardiovasc Imaging 2021 May 16. Epub 2021 May 16.

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

Purpose: Histopathological or intracoronary image assessment of healed plaques (HPs) has been reported. However, the lesion characteristics of HPs remains undetermined yet. We assessed the healed plaque components in patients with coronary artery lesions using multiple imaging modalities. Read More

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Effectiveness and Tolerability of the Single-Pill Combination of Bisoprolol and Perindopril in Patients with Arterial Hypertension and Stable Coronary Artery Disease in Daily Clinical Practice: The STYLE Study.

Adv Ther 2021 Jun 15;38(6):3299-3313. Epub 2021 May 15.

Department of Angiology, National Medical Research Center of Cardiology of the Ministry of Health of Russia, Moscow, Russia.

Introduction: Combination antihypertensive therapy is required by most patients to achieve guideline-recommended blood pressure (BP) goals. This study assessed the effectiveness and tolerability of bisoprolol/perindopril (Bis/Per) single-pill combination (SPC) in Russian patients with hypertension and coronary artery disease (CAD) treated in routine clinical practice.

Methods: STYLE (NCT03730116) was an open-label, uncontrolled, prospective observational study conducted in patients who were already receiving Bis/Per SPC, switched to SPC from Bis or Per monotherapy, or switched from a free combination of Bis and Per. Read More

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Ramadan fasting: recommendations for patients with cardiovascular disease.

Heart 2021 May 14. Epub 2021 May 14.

Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, UK

Ramadan fasting is observed by most of the 1.8 billion Muslims around the world. It lasts for 1 month per the lunar calendar year and is the abstention from any food and drink from dawn to sunset. Read More

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Single direct oral anticoagulant therapy in stable patients with atrial fibrillation beyond 1 year after coronary stent implantation.

Heart 2021 May 14. Epub 2021 May 14.

Division of Cardiology, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

Objective: Optimal antithrombotic therapy in patients with atrial fibrillation (AF) beyond 1 year after coronary stent implantation has not been well established in the era of direct oral anticoagulant (DOAC).

Methods: Using Korean National Health Insurance Service data, we analysed 4294 patients with AF who were prescribed DOAC beyond 1 year after coronary stent implantation. Subjects were classified into the monotherapy group (DOAC single therapy, n=1221) or the combination therapy group (DOAC with an antiplatelet agent, n=3073). Read More

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Efficacy and Safety of Long-Term Evolocumab Use Among Asian Subjects - A Subgroup Analysis of the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) Trial.

Circ J 2021 May 12. Epub 2021 May 12.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School.

Background: There are concerns that Asian patients respond differently to some medications. This study evaluated the efficacy and safety of evolocumab among Asian vs. other subjects in the FOURIER trial, which randomized stable atherosclerosis patients to receive either evolocumab or placebo. Read More

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What Is the Role of Assessing Ischemia to Optimize Therapy and Outcomes for Patients with Stable Angina and Non-obstructed Coronary Arteries?

Cardiovasc Drugs Ther 2021 May 12. Epub 2021 May 12.

Division of Cardiovascular Medicine, University of Florida, Gainesville, FL, USA.

Ischemic heart disease (IHD) is a leading global cause of ill-health and premature death. Clinical research into IHD is providing new insights into the pathophysiology, epidemiology and treatment of this condition. The major endotypes of IHD include coronary heart disease (CHD) and vasomotor disorders, including microvascular angina and vasospastic angina. Read More

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IMPACT OF THE PLACEBO EFFECT ON SYMPTOMS, QUALITY OF LIFE AND FUNCTIONAL OUTCOMES IN ANGINA PECTORIS: A meta-analysis of randomized placebo-controlled trials.

Can J Cardiol 2021 May 8. Epub 2021 May 8.

Division of Cardiology, Department of Internal Medicine, Città della Salute e della Scienza, Torino.

Background: The placebo effect is a well described phenomenon in blinded studies evaluating anti-anginal therapeutics, although its impact on clinical research metrics remains unknown. We conducted a systematic review and meta-analysis to quantify the impact of placebo on endpoints of symptoms, life-quality and functional outcomes in randomized placebo-controlled trials (RCTs) of symptomatic stable coronary artery disease.

Methods: We systematically reviewed MEDLINE, EMBASE, and the Cochrane database for double-blind RCTs of anti-angina therapeutics. Read More

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Efficacy and safety of Naoxintong capsule for treating chronic stable angina: study protocol for a randomized controlled trial.

Trials 2021 May 10;22(1):336. Epub 2021 May 10.

The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510006, Guangdong Province, China.

Background: Cardiovascular disease is the leading cause of mortality and morbidity worldwide, Chronic stable angina (CSA) is the main symptom of myocardial ischemia, causes increased risk of major cardiovascular events such as sudden cardiac death and myocardial infarction. Naoxintong (NXT) capsule is a classical traditional Chinese medication used to treat CSA, however, few evidence to support the wide utility of NXT capsule for the treatment of CSA. We design this study to evaluate the efficacy and safety of NXT capsule versus placebo in patients with CSA. Read More

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Diagnostic Value of Circulating Progranulin and Its Receptor EphA2 in Predicting the Atheroma Burden in Patients with Coronary Artery Disease.

Dis Markers 2021 21;2021:6653501. Epub 2021 Apr 21.

Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, China.

Background: Progranulin (PGRN) and its potential receptor Eph-receptor tyrosine kinase-type A2 (EphA2) are inflammation-related molecules that present on the atherosclerotic plaques. However, the roles of circulating PGRN and EphA2 in coronary artery disease (CAD) remain unclear.

Objective: To study the clinical significance of circulating PGRN and EphA2 levels in Chinese patients undergoing coronary angiography. Read More

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Yanyu Decoction for Aged Patients with Stable Coronary Artery Disease: A Systematic Review and Meta-Analysis.

Evid Based Complement Alternat Med 2021 17;2021:6615035. Epub 2021 Apr 17.

Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.

Background: There was limited evidence of treatments aiming at aged coronary artery disease (CAD) patients. Yanyu decoction (YD) has been used as adjuvant therapy in aged patients with stable CAD and might be a new treatment worthy of recommendation for CAD patients. This study was to evaluate the combined effects of YD plus conventional pharmaceutical treatment (CPT) on senile patients with stable CAD. Read More

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