34,654 results match your criteria specific morphological

PCR-based rapid diagnostic tools for the authentication of medicinal mistletoe species.

Phytomedicine 2021 Jul 16;91:153667. Epub 2021 Jul 16.

Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, 111, Geonjae-ro, Naju, Jeollanam-do 58245, Republic of Korea. Electronic address:

Background: Taxilli Herba (TH) and Visci Herba (VH), defined as the leaves and branches of the mistletoe species Taxillus chinensis and Viscum coloratum, respectively, are popular herbal medicines in East Asia. However, commercial TH and VH products are frequently adulterated with related inauthentic mistletoe species, posing efficacy and safety concerns. Accurate species identification of herbal medicinal products is a prerequisite for quality control, but traditional morphological identification methods are hampered by difficulties in discriminating among closely related species and in identifying the source materials in processed products. Read More

View Article and Full-Text PDF

Phylogenetic analysis of lice infested chicken (Gallus gallus domisticus) with new records in Kurdistan of Iraq.

Ann Parasitol 2021 ;67(2):161-168

Department of Biology, College of Sciences, University of Duhok, Kurdistan Region-Iraq.

The domestic chickens are the most important protein sources of human populations in every part of the world; many parasites' species may affect birds. Ectoparasites can be found practically in all birds. They feed on their body components like blood, feathers. Read More

View Article and Full-Text PDF
January 2021

Characterization of Clinostomum sp. (Trematoda: Clinostomidae) infecting cormorants in south-eastern Australia.

Parasitol Res 2021 Jul 31. Epub 2021 Jul 31.

Fisheries and Aquaculture Management, NSW Department of Primary Industries, Narrandera Fisheries Centre, Narrandera, NSW, 2700, Australia.

Clinostomum Leidy, 1856 (Trematoda: Clinostomidae) is a cosmopolitan, zoonotic genus of fluke that has been poorly studied in an Australian setting. Following previous reports of reservoir fish in Australian fish ponds being heavily infected with Clinostomum metacercaria, the current study was conducted to determine the specific identity of Clinostomum sp. in inland Australia, by examining and characterizing parasites collected from a potential definitive host, cormorants. Read More

View Article and Full-Text PDF

Efficient parallel simulation of hemodynamics in patient-specific abdominal aorta with aneurysm.

Comput Biol Med 2021 Jul 24;136:104652. Epub 2021 Jul 24.

Department of Mathematics, University of Macau, Macau, China. Electronic address:

Surgical planning for aortic aneurysm repair is a difficult task. In addition to the morphological features obtained from medical imaging, alternative features obtained with computational modeling may provide additional useful information. Though numerical studies are noninvasive, they are often time-consuming, especially when we need to study and compare multiple repair scenarios, because of the high computational complexity. Read More

View Article and Full-Text PDF

Quantitative Biomarkers for Cancer Detection Using Contrast-Free Ultrasound High-Definition Microvessel Imaging: Fractal Dimension, Murray's Deviation, Bifurcation Angle & Spatial Vascularity Pattern.

IEEE Trans Med Imaging 2021 Jul 30;PP. Epub 2021 Jul 30.

A growing body of evidence indicates that there is a strong correlation between microvascular morphological features and malignant tumors. Therefore, quantification of these features might allow more accurate differentiation of benign and malignant tumors. The main objective of this research project is to improve the quantification of microvascular networks depicted in contrast-free ultrasound microvessel images. Read More

View Article and Full-Text PDF

Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells.

Environ Health Perspect 2021 Jul 30;129(7):77007. Epub 2021 Jul 30.

Department of Biology, University of Ottawa, Ottawa, Ontario, Canada.

Background: Global concerns of methylmercury (MeHg) exposure have been raised, especially on its effects on pregnant women. Recent epidemiological studies have revealed associations between maternal blood/hair MeHg concentrations, adverse pregnancy outcomes, and developmental deficits. However, the underlying mechanisms remain unclear. Read More

View Article and Full-Text PDF

Morpho-molecular diversity and avirulence genes distribution among the diverse isolates of Magnaporthe oryzae from southern India.

J Appl Microbiol 2021 Jul 30. Epub 2021 Jul 30.

Rice Pathology Laboratory, Agricultural Research Station, Gangavathi, University of Agricultural Sciences, Raichur, Karnataka, India.

Aims: To investigate the diversity of eco-distinct isolates of Magnaporthe oryzae for their morphological, virulence, and molecular diversity and relative distribution of five Avr genes.

Methods And Results: Fifty-two M. oryzae isolates were collected from different rice ecosystems of southern India. Read More

View Article and Full-Text PDF

Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons.

Front Neurosci 2021 7;15:680572. Epub 2021 Jul 7.

Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Pathogenic variants in are the most frequent cause of autosomal recessive complicated hereditary spastic paraplegia (HSP). In addition to spastic paraplegia caused by corticospinal degeneration, most patients are significantly affected by progressive weakness and muscle wasting due to alpha motor neuron (MN) degeneration. Mitochondria play a crucial role in neuronal health, and mitochondrial deficits were reported in other types of HSPs. Read More

View Article and Full-Text PDF

The Arabidopsis expansin gene (AtEXPA18) is capable to ameliorate drought stress tolerance in transgenic tobacco plants.

Mol Biol Rep 2021 Jul 29. Epub 2021 Jul 29.

Department of Agronomy and Plant Breeding, Faculty of Agricultural Science and Engineering, University College of Agriculture and Natural Resources, University of Tehran, Karaj, Islamic Republic of Iran.

Background: Expansins are cell wall proteins loosening plant cell in pH-dependent manner. This study aimed to investigate the role of AtEXPA18 in different morphological, physiological, and cellular responses of transgenic tobacco plants to moderate and severe drought stress.

Methods And Results: Previously synthesized AtEXPA18 gene construct was successfully transferred to the tobacco plants through an agrobacterium-mediate transformation system. Read More

View Article and Full-Text PDF

Topologically convergent and divergent morphological gray matter networks in early-stage Parkinson's disease with and without mild cognitive impairment.

Hum Brain Mapp 2021 Jul 28. Epub 2021 Jul 28.

Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Patients with Parkinson's disease with mild cognitive impairment (PD-M) progress to dementia more frequently than those with normal cognition (PD-N), but the underlying neurobiology remains unclear. This study aimed to define the specific morphological brain network alterations in PD-M, and explore their potential diagnostic value. Twenty-four PD-M patients, 17 PD-N patients, and 29 healthy controls (HC) underwent a structural MRI scan. Read More

View Article and Full-Text PDF

Cultured Horse Articular Chondrocytes in 3D-Printed Chitosan Scaffold With Hyaluronic Acid and Platelet Lysate.

Front Vet Sci 2021 12;8:671776. Epub 2021 Jul 12.

Department of Veterinary Science, University of Parma, Parma, Italy.

Three-dimensional (3D) printing has gained popularity in tissue engineering and in the field of cartilage regeneration. This is due to its potential to generate scaffolds with spatial variation of cell distribution or mechanical properties, built with a variety of materials that can mimic complex tissue architecture. In the present study, horse articular chondrocytes were cultured for 2 and 4 weeks in 3D-printed chitosan (CH)-based scaffolds prepared with or without hyaluronic acid and in the presence of fetal bovine serum (FBS) or platelet lysate (PL). Read More

View Article and Full-Text PDF

Specific cell differentiation in breast cancer: a basis for histological classification.

J Clin Pathol 2021 Jul 28. Epub 2021 Jul 28.

Histopathology, St. Vincent's Hospital, Dublin, Ireland.

Breast parenchyma progenitor cells show a high degree of phenotypic plasticity reflected in the wide range of morphology observed in benign and malignant breast tumours. Although there is evidence suggesting that all breast cancer (BC) arises from a common epithelial progenitor or stem cell located at the terminal duct lobular units (TDLUs), BC shows a broad spectrum of morphology with extensive variation in histological type and grade. This is related to the complexity of BC carcinogenesis including initial genetic changes in the cell of origin, subsequent genetic and epigenetic alterations and reprogramming that occur at various stages of BC development and the interplay with the surrounding microenvironment, factors which influence the process of differentiation. Read More

View Article and Full-Text PDF

A multiplex PCR assay for six Aedini species, including Aedes albopictus.

Parasit Vectors 2021 Jul 28;14(1):380. Epub 2021 Jul 28.

School of Life Sciences, Kyungpook National University, Biology building 226, Daehak-ro 80, Daegu, Korea.

Background: Mosquitoes, as vectors of various human pathogens, are significant drivers of serious human illness. In particular, those species in the Aedini tribe, which typically transmit dengue virus, Chikungunya fever virus, and Zika virus, are increasing their range because of climate change and international commerce. In order to evaluate the risk of disease transmission, accurate mosquito species identification and monitoring are needed. Read More

View Article and Full-Text PDF

Case Report: Polyvinylpyrrolidone deposition disease from repeated injection of opioid substitution drugs: report of a case with a fatal outcome.

F1000Res 2021 19;10:300. Epub 2021 Apr 19.

Department of Pathology, Haukeland University Hospital, Post box 1, 5021 Bergen, Norway.

: Intravenous injection of oral opioid substitution drugs (OSD) is widespread among injecting drug users. Several OSDs contain the polymer polyvinylpyrrolidone (PVP) as an excipient. Parenterally administered PVP of high molecular weight may accumulate in tissues and organs. Read More

View Article and Full-Text PDF

First Report of Lotus Seedpod Withering Caused by Fusarium proliferatum on Nelumbo nucifera Plants in China.

Plant Dis 2021 Jul 28. Epub 2021 Jul 28.

Jiangxi Agricultural University, 91595, College of Agronomy, Zhimin Road, Nanchang, China, 330045;

Nelumbo nucifera (Nymphaeaceae family) is a well-known plant in China and with the increasing value of this crop, the planting area of lotus is expanding. In May 2019, an unknown withering lotus seedpod was obtained in Guangchang County of Jiangxi Province (26.79°N, 116. Read More

View Article and Full-Text PDF

Nuclear factor-kappa B (NF-κB) decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid (PLGA) nanospheres promote periodontal tissue healing after tooth replantation in rats.

J Periodontol 2021 Jul 28. Epub 2021 Jul 28.

Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Background: Excessive inflammation in the periodontal tissue after tooth replantation can lead to inflammatory root resorption and interrupt periodontal tissue regeneration. We tested the hypothesis that NF-κB decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres (NF-PLGA) inhibit excessive inflammation and promote healing of periodontal tissue after replantation in rats.

Methods: The upper right incisors of rats were extracted, immersed in different specific solutions, and replanted. Read More

View Article and Full-Text PDF

Atg5 knockdown induces age-dependent cardiomyopathy which can be rescued by repeated remote ischemic conditioning.

Basic Res Cardiol 2021 Jul 28;116(1):47. Epub 2021 Jul 28.

The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA.

Altered autophagy is implicated in several human cardiovascular diseases. Remote ischemic conditioning (RIC) is cardioprotective in multiple cardiovascular injury models and modifies autophagy signaling, but its effect in cardiomyopathy induced by gene manipulation has not been reported. To investigate the cardiac effects of chronically reduced autophagy as a result of Atg5 knockdown and assess whether RIC can rescue the phenotype. Read More

View Article and Full-Text PDF

Crescents in primary glomerulonephritis: a pattern of injury with dissimilar actors. A pathophysiologic perspective.

Pediatr Nephrol 2021 Jul 27. Epub 2021 Jul 27.

Nephrology Service, Hospital Británico de Buenos Aires, Perdriel 74 (1280), Buenos Aires, Argentina.

Cellular crescents are defined as two or more layers of proliferating cells in Bowman's space and are a hallmark of inflammatory active glomerulonephritis and a histologic marker of severe glomerular injury. In general, the percentage of glomeruli that exhibit crescents correlates with the severity of kidney failure and other clinical manifestations of nephritic syndrome. In general, a predominance of active crescents is associated with rapidly progressive glomerulonephritis and a poor outcome. Read More

View Article and Full-Text PDF

Evaluation of liver histopathological findings of COVID-19 by minimally invasive autopsies.

J Clin Exp Hepatol 2021 Jul 21. Epub 2021 Jul 21.

Department of Surgical Oncology, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan- 342005, India.

Aim: The SARS-CoV-2 outbreak resulted in severe health impact with the loss of many lives across the world. Pulmonary parenchyma suffers most from the brunt of the infection. However, evidence suggested a systemic involvement during the course of illness. Read More

View Article and Full-Text PDF

Multiple paths to morphological diversification during the origin of amniotes.

Nat Ecol Evol 2021 Jul 26. Epub 2021 Jul 26.

Department of Earth Sciences, University of Oxford, Oxford, UK.

Early terrestrial vertebrates (amniotes) provide a classic example of diversification following adaptive zone invasion. The initial terrestrialization of vertebrates was closely followed by dietary diversification, as evidenced by a proliferation of craniomandibular and dental adaptations. However, morphological evolution of early amniotes has received limited study, in analyses with restricted taxonomic scope, leaving substantial questions about the dynamics of this important terrestrial radiation. Read More

View Article and Full-Text PDF

Infection with Human Papillomavirus 18 Promotes Alkylating Agent-Induced Malignant Transformation in a Human Esophageal Cell Line.

Chem Res Toxicol 2021 Jul 23. Epub 2021 Jul 23.

Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, P.R. China.

The relationship between human papillomavirus (HPV) and esophageal cancer (EC) has been controversial, which may be caused by the difference in geographic regions of sample origin. Thus, we conducted a case-control study to find that HPV increased the risk of esophageal cancer, and the HPV18 detection rate is the highest (24.2%) among patients with EC, suggesting that HPV18 could be the most risk subtype of HPV infected. Read More

View Article and Full-Text PDF

Depression of Pyroptosis by Inhibiting Caspase-1 Activation Improves Neurological Outcomes of Kernicterus Model Rats.

ACS Chem Neurosci 2021 Jul 23. Epub 2021 Jul 23.

Department of Neonatology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, China.

Kernicterus is a severe complication of extreme neonatal hyperbilirubinemia. Prolonged exposure to high-level unconjugated bilirubin (UCB) directly damages brain tissue. Neuroinflammation is believed to contribute to UCB-induced neurotoxicity. Read More

View Article and Full-Text PDF

In Vivo Super-Resolution Track-Density Imaging for Thalamic Nuclei Identification.

Cereb Cortex 2021 Jul 23. Epub 2021 Jul 23.

Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Images, University of Messina, 98124 Messina, Italy.

The development of novel techniques for the in vivo, non-invasive visualization and identification of thalamic nuclei has represented a major challenge for human neuroimaging research in the last decades. Thalamic nuclei have important implications in various key aspects of brain physiology and many of them show selective alterations in various neurologic and psychiatric disorders. In addition, both surgical stimulation and ablation of specific thalamic nuclei have been proven to be useful for the treatment of different neuropsychiatric diseases. Read More

View Article and Full-Text PDF

Hepatocellular carcinoma: a clinical and pathological overview.

Pathologica 2021 Jun;113(3):203-217

Department of Biomedical Sciences, Humanitas University, Milan, Italy.

HCC incidence rates have been rising in the past 3 decades and by 2025 > 1 million individuals will be affected annually. High-throughput sequencing technologies led to the identification of several molecular HCC subclasses that can be broadly grouped into 2 major subgroups, each characterized by specific morphological and phenotypical features. It is likely that this increasing knowledge and a more appropriate characterization of HCC at the pathological level will impact HCC patient management. Read More

View Article and Full-Text PDF

Feature level-based group lasso method for amnestic mild cognitive impairment diagnosis.

Comput Methods Programs Biomed 2021 Jul 16;208:106286. Epub 2021 Jul 16.

School of Biological Science and Medical Engineering, Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing 100083, China; State Key Lab of Cognition Neuroscience and Learning, Beijing Normal University, Beijing 100875, China. Electronic address:

Background And Objective: Previous studies have indicated that brain morphological measures change in patients with amnestic mild cognitive impairment (aMCI). However, most existing classification methods cannot take full advantage of these measures. In this study, we improve traditional multitask learning framework by fully considering the relevance among related tasks and supplementary information from other unrelated tasks at the same time. Read More

View Article and Full-Text PDF

Mitotropic Triphenylphosphonium Doxorubicin-Loaded Core-Shell Nanoparticles for Cellular and Mitochondrial Sequential Targeting of Breast Cancer.

Int J Pharm 2021 Jul 23:120936. Epub 2021 Jul 23.

Nanomedicine Labs, Center for Materials Science (CMS), Zewail City of Science and Technology, 6 of October City, 12578, Giza, Egypt. Electronic address:

Hypotheses Targeted therapy exploits cancerous niches' properties including acidic extracellular environment, hypoxic tumor core, and tumor-specific surface antigens. The present study aims to develop and evaluate a sequential targeted core-shell nanoparticulate (NPs) system for treatment of breast cancer. Sequential (double-stage) targeting was achieved at the cellular-level employing the selective CD44- receptor binding hyaluronic acid (HA), followed by subcellular mitochondrial drug-delivery using a synthesized triphenylphosphonium-conjugated doxorubicin (DOX-TPP). Read More

View Article and Full-Text PDF

The impact of hindlimb disuse on sepsis-induced myopathy in mice.

Physiol Rep 2021 Jul;9(14):e14979

Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL, USA.

Sepsis induces a myopathy characterized by loss of muscle mass and weakness. Septic patients undergo prolonged periods of limb muscle disuse due to bed rest. The contribution of limb muscle disuse to the myopathy phenotype remains poorly described. Read More

View Article and Full-Text PDF

miRNA-34 and miRNA-210 target hexamerin genes enhancing their differential expression during early brain development of honeybee (Apis mellifera) castes.

Insect Mol Biol 2021 Jul 26. Epub 2021 Jul 26.

Departamento de Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, UNIFAL-MG, Alfenas, Minas Gerais, Brazil.

During the honeybee larval stage, queens develop larger brains than workers, with morphological differentiation appearing at the fourth larval phase (L4), just after a boost in nutritional difference both prospective females experience. The molecular promoters of this caste-specific brain development are already ongoing in previous larval phases. Transcriptomic analyses revealed a set of differentially expressed genes in the L3 brains of queens and workers, which represents the early molecular response to differential feeding females receive during larval development. Read More

View Article and Full-Text PDF

Leaf density and chemical composition explain variation in leaf mass area with spectral composition among 11 widespread forbs in a common garden.

Physiol Plant 2021 Jul 26. Epub 2021 Jul 26.

Forestry and Forest Products Research Institute, 1 Matsunosato, Ibaraki, Japan.

Leaf mass per area (LMA) is a key leaf functional trait correlated with plant strategies dictating morphology, physiology, and biochemistry. Although sunlight is generally accepted as a dominant factor driving LMA, the contribution of each spectral region of sunlight in shaping LMA is poorly understood. In the present study, we grew 11 widespread forb species in a common garden and dissected the traits underpinning differences in LMA, such as its morphological components (leaf density (LD), and leaf thickness (LT)), macroelement and metabolite composition under five spectral-attenuation treatments: (1) transmitting c. Read More

View Article and Full-Text PDF

Inter- and intraspecific variation in the species complex demonstrates size and shape partitioning among species.

PeerJ 2021 12;9:e11777. Epub 2021 Jul 12.

Cell Biology and Anatomy, Louisiana State University Health Sciences Center- New Orleans, New Orleans, United States of America.

Neotropical leaf-nosed bats (family Phyllostomidae) are one of the most diverse mammalian families and spp. is one of the most speciose phyllostomid genera. In spite of their species diversity, previous work on crania using linear morphometrics has uncovered limited interspecific variation. Read More

View Article and Full-Text PDF