62,215 results match your criteria species sensitive

Development of highly sensitive one step-PCR tests for improved detection of B. bigemina and B. bovis.

Vet Parasitol 2021 Jun 8;296:109493. Epub 2021 Jun 8.

Instituto de Agrobiotecnología y Biología Molecular (IABIMO) INTA - CONICET, de Los Reseros y Dr. Nicolás Repetto s/n, P.O. Box 25 (B1712WAA), Castelar, Buenos Aires, Argentina.

Bovine babesiosis caused by Babesia bigemina and B. bovis is an economically relevant tick-borne disease distributed over tropical and subtropical world regions. Animals that recover from the clinical disease can remain persistently infected, and those carriers are epidemiologically relevant since they can act as a source of infection to other animals through the tick bite. Read More

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A rabbit monoclonal antibody-mediated lateral flow immunoassay for rapid detection of CTX-M extended-spectrum β-lactamase-producing Enterobacterales.

Int J Biol Macromol 2021 Jun 12. Epub 2021 Jun 12.

Department of Microbiology and Immunology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan. Electronic address:

Infections of CTX-M extended-spectrum β-lactamase-producing Enterobacterales are a severe threat in clinical settings. CTX-M genes on plasmids have been transferred to many Enterobacterales species, and these species have spread, leading to the global problem of antimicrobial resistance. Here, we developed a lateral flow immunoassay (LFIA) based on an anti-CTX-M rabbit monoclonal antibody. Read More

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Landfast ice: a major driver of reproductive success in a polar seabird.

Biol Lett 2021 Jun 16;17(6):20210097. Epub 2021 Jun 16.

Centre d'Études Biologiques de Chizé (CEBC), CNRS UMR 7372, 79360 Villiers en Bois, France.

In a fast-changing world, polar ecosystems are threatened by climate variability. Understanding the roles of fine-scale processes, and linear and nonlinear effects of climate factors on the demography of polar species is crucial for anticipating the future state of these fragile ecosystems. While the effects of sea ice on polar marine top predators are increasingly being studied, little is known about the impacts of landfast ice (LFI) on this species community. Read More

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Clarithromycin As an Alternative and Prophylactic Agent in a Hematopoietic Stem Cell Transplantation Patient.

Am J Case Rep 2021 Jun 15;22:e931731. Epub 2021 Jun 15.

Medical Mycology Research Center, Chiba University, Chiba, Japan.

BACKGROUND Nocardia infections have rarely been reported in hematopoietic stem cell transplantation (HSCT) patients, who usually receive the prophylactic use of sulfamethoxazole/trimethoprim (ST) against Pneumocystis jiroveci. However, the ST prophylaxis, sensitive to Nocardia species, sometimes induces renal toxicities. Therefore, alternative prophylactic or therapeutic drugs are required for nocardiosis in HSCT patients. Read More

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Role of Toxicokinetic and Toxicodynamic Parameters in Explaining the Sensitivity of Zebrafish Larvae to Four Metals.

Environ Sci Technol 2021 Jun 15. Epub 2021 Jun 15.

Key Laboratory of Pollution Process and Environmental Criteria of Ministry of Education and Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, P. R. China.

Given the persistence and toxic potencies of metal contaminants in ecosystems, animals, and human beings, they are considered to be hazardous global pollutants. While the lethality of metal toxicities (e.g. Read More

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Development of a miniature time-of-flight mass spectrometer coupled with an improved substrate-enhanced laser-induced acoustic desorption source (SE-LIAD/TOF-MS).

Analyst 2021 Jun 15. Epub 2021 Jun 15.

State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.

A novel, compact and sensitive SE-LIAD/TOF-MS has been described. It facilitates fast sample preparation, and a full mass spectrum is acquired efficiently and sensitively. More importantly, it features the detection of non-acidic and non-basic or non-polar species, which is not suitable for determination by ESI and MALDI techniques. Read More

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Rapid and simple detection of in strawberry using a coupled recombinase polymerase amplification-lateral flow strip assay.

Phytopathol Res 2021 10;3(1):12. Epub 2021 Jun 10.

College of Plant Protection, Nanjing Agricultural University, Nanjing, 210095 China.

is a devastating pathogen that infects a wide range of plants and causes Phytophthora rot disease, which has resulted in great economic losses in crop production. Therefore, the rapid and practicable detection of is important for disease monitoring and forecasting. In this study, we developed a lateral flow recombinase polymerase amplification (LF-RPA) assay for the sensitive visual detection of . Read More

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Development of predictive models evaluating the spoilage-delaying effect of a bioprotective culture on different yeast species in yogurt.

J Dairy Sci 2021 Jun 11. Epub 2021 Jun 11.

Department of Dairy Bioprotection, Chr. Hansen A/S, Boege Allé 10-12, 2970 Hoersholm, Denmark.

Yeast spoilage of fermented dairy products causes challenges for the dairy industry, including economic losses due to wasted product. Food cultures with bioprotective effects are becoming more widely used to help ensure product quality throughout product shelf life. To assist the dairy industry when evaluating product quality throughout shelf life and the effect of bioprotective cultures, we aimed to build stochastic models that provide reliable predictions of yeast spoilage in yogurt with and without bioprotective culture. Read More

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Phytoremediation of azoxystrobin and imidacloprid by wetland plant species , and .

Int J Phytoremediation 2021 Jun 14:1-9. Epub 2021 Jun 14.

Department of Crop and Soil Sciences, North Carolina State University, Raleigh, NC, USA.

Azoxystrobin (strobilurin fungicide) and imidacloprid (neonicotinoid insecticide) have been detected in surface waters near treated agricultural, urban, and mixed landscapes. The hazards of pesticide runoff can be prevented through best management practices, including the establishment of diverse wetland plant barriers that can phytoremediate the chemicals in which they come into contact with. In this study, the wetland plant species softrush (), pickerelweed (), and arrowhead ( were planted in sandy soil containers that were then placed in azoxystrobin or imidacloprid treated water. Read More

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NIR nanoprobe-facilitated cross-referencing manifestation of local disease biology for dynamic therapeutic response assessment.

Chem Sci 2019 Nov 27;11(3):803-811. Epub 2019 Nov 27.

Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University Singapore 637371 Singapore

Pharmacological interventions for effective treatment require opportune, dynamic and accurate manifestation of pathological status. Traditional clinical techniques relying on biopsy-based histological examinations and blood tests are dramatically restricted due to their invasiveness, unsatisfactory precision, non-real-time reporting and risk of complications. Although current strategies through molecular imaging enable non-invasive and spatiotemporal mapping of pathological changes in intact organisms, environment-activatable, sensitive and quantitative sensing platforms, especially for dynamic feedback of the therapeutic response, are still urgently desired in practice. Read More

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November 2019

Biomimetic nanochannels for the discrimination of sialylated glycans a tug-of-war between glycan binding and polymer shrinkage.

Chem Sci 2019 Dec 3;11(3):748-756. Epub 2019 Dec 3.

Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences 457 Zhongshan Road Dalian 116023 China

Sialylated glycans that are attached to cell surface mediate diverse cellular processes such as immune responses, pathogen binding, and cancer progression. Precise determination of sialylated glycans, particularly their linkage isomers that can trigger distinct biological events and are indicative of different cancer types, remains a challenge, due to their complicated composition and limited structural differences. Here, we present a biomimetic nanochannels system integrated with the responsive polymer polyethyleneimine--glucopyranoside (Glc-PEI) to solve this problem. Read More

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December 2019

Solid-state NMR spectroscopy: an advancing tool to analyse the structure and properties of metal-organic frameworks.

Chem Sci 2020 Apr 6;11(17):4297-4304. Epub 2020 Apr 6.

Chair of Bioanalytical Chemistry, Faculty of Chemistry and Food Chemistry, TU Dresden 01062 Dresden Germany

Metal-organic frameworks (MOFs) gain increasing interest due to their outstanding properties like extremely high porosity, structural variability, and various possibilities for functionalization. Their overall structure is usually determined by diffraction techniques. However, diffraction is often not sensitive for subtle local structural changes and ordering effects as well as dynamics and flexibility effects. Read More

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Grafting resulting in alleviating tomato plant oxidative damage caused by high levels of ofloxacin.

Environ Pollut 2021 May 14;286:117331. Epub 2021 May 14.

College of Horticulture Science and Engineering, Shandong Agricultural University, Tai'an, 271018, PR China; Collaborative Innovation Center of Fruit & Vegetable Quality and Efficient Production in Shandong, PR China; State Key Laboratory of Crop Biology, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops in Huanghuai Region, Ministry of Agriculture and Rural Affairs, PR China; State Key Laboratory of Crop Biology, Ministry of Agriculture, PR China. Electronic address:

Antibiotic pollution has become a global problem threatening human health. Ofloxacin is one of the more widely used antibiotics, but reports on the reaction of plant to ofloxacin pollution are limited. In this study, using adversity-resistant (R), adversity-sensitive (S) and grafted plant S/R as models, we investigated the biological response of tomato to exogenous ofloxacin residues. Read More

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Assessing the risk of light reduction from natural sediment resuspension events and dredging activities in an inshore turbid reef environment.

Mar Pollut Bull 2021 Jun 11;170:112536. Epub 2021 Jun 11.

Australian Institute of Marine Science, Townsville, QLD and Perth, WA, Australia; The UWA Oceans Institute University of Western Australia, WA, Australia. Electronic address:

The reduction in benthic light from natural sediment resuspension events, dredging activities and clouds was quantified over multiple time periods (days to weeks) from a 3-year in-situ field study in the inshore turbid-zone coral communities of the Great Barrier Reef. The results were then used to examine the tolerance levels of three coral species and a sponge to light reduction and associated changes in spectral light quality (in conjunction with elevated sediment concentrations) in a 28-day laboratory-based study. All species survived the exposures but sub-lethal responses involving changes in pigmentation, lipids and lipid ratios were observed. Read More

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Assessing the potential to harness the microbiome through plant genetics.

Curr Opin Biotechnol 2021 Jun 11;70:167-173. Epub 2021 Jun 11.

LIPME, Université de Toulouse, INRAE, CNRS, Castanet-Tolosan, France.

Microbial communities are influenced by a complex system of host effects, including traits involved in physical barriers, immunity, hormones, metabolisms and nutrient homeostasis. Variation of host control within species is governed by many genes of small effect and is sensitive to biotic and abiotic environments. On the flip side, these host impacts seem targeted on particular microbial species, with that impact percolating through the microbial community. Read More

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A planetary health model for reducing exposure to faecal contamination in urban informal settlements: Baseline findings from Makassar, Indonesia.

Environ Int 2021 Jun 12;155:106679. Epub 2021 Jun 12.

Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia; International Institute for Global Health, United Nations University, Kuala Lumpur, Malaysia.

Background: The intense interactions between people, animals and environmental systems in urban informal settlements compromise human and environmental health. Inadequate water and sanitation services, compounded by exposure to flooding and climate change risks, expose inhabitants to environmental contamination causing poor health and wellbeing and degrading ecosystems. However, the exact nature and full scope of risks and exposure pathways between human health and the environment in informal settlements are uncertain. Read More

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Bacterial Skin Infections in Hospitalized Patients with Bullous Pemphigoid.

Adv Skin Wound Care 2021 Jul;34(7):365-370

In the Dermatology Department, Peking University First Hospital, Beijing, China, Furong Li, MB, is a medical student; Xuejun Zhu, MD, is a professor; Xixue Chen, MD, is an associate professor; Mingyue Wang, MD, PhD, is an associate professor. In the Eight-year Clinical Medical Education Department, Wenjie Bian, MB and Yejun Wu, MB, are medical students. Acknowledgment: This study was supported by the National Natural Science Foundation of China (grant no. 81000694 and 81130030) and the Beijing Natural Science Foundation (grant no. 7172214). The funders played no role in study design, data collection, data analysis, manuscript writing, or publication. The authors have disclosed no other financial relationships related to this article. Submitted May 9, 2020; accepted in revised form October 2, 2020.

Objective: To explore the features and risk factors of bacterial skin infections (BSIs) in hospitalized patients with bullous pemphigoid (BP).

Methods: Records were retrospectively reviewed for 110 hospitalized patients with BP admitted to Peking University First Hospital between 2013 and 2019. Bacterial species and drug resistance were assessed, and then the underlying risk factors for BSIs were evaluated. Read More

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Novel Mitochondria-Targeting and Naphthalimide-based Fluorescent Probe for Detecting HClO in Living Cells.

ACS Omega 2021 Jun 26;6(22):14399-14409. Epub 2021 May 26.

School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, PR China.

As a key reactive oxygen species (ROS), hypochlorous acid (HClO) plays an important role in many physiological and pathological processes. The mitochondria-targeting probes for the highly sensitive detection of HClO are desirable. In present work, we designed and synthesized an original mitochondria-localizing and turn-on fluorescent probe for detecting HClO. Read More

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A retrospective study on the microbial spectrum and antibiogram of uropathogens in children in a secondary care hospital in Rural Vellore, South India.

J Family Med Prim Care 2021 Apr 29;10(4):1706-1711. Epub 2021 Apr 29.

Department of Community Health, Christian Medical College, Vellore, Tamil Nadu, India.

Background: Urinary tract infection (UTI) is common among children. Empiric antibiotics have to be started as early as possible or it may lead to an irreversible renal parenchymal damage and renal scarring in children. The objectives were to determine the prevalence and microbial profile of paediatric UTI and to determine the antimicrobial susceptibility pattern. Read More

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Macrophyte and indigenous bacterial co-remediation process for pentachlorophenol removal from wastewater.

Int J Phytoremediation 2021 Jun 12:1-12. Epub 2021 Jun 12.

Water Treatment and Recycling Laboratory, Water Research and Technology Center (CERTE), Technopole Borj-Cédria, Soliman, Tunisia.

This study has contributed in the description of bioaugmentation-phytoremediation efficiency process using concerning PCP tolerance and removal from wastewater. Samples of wastewater were collected from industrial wastewater plants, namely row wastewater effluent "E.WW", primary wastewater "P. Read More

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Anthropogenic disturbance favours generalist over specialist parasites in bird communities: Implications for risk of disease emergence.

Ecol Lett 2021 Jun 13. Epub 2021 Jun 13.

Indian Institute of Science Education and Research Tirupati, Tirupati, Andhra Pradesh, India.

Niche theory predicts specialists which will be more sensitive to environmental perturbation compared to generalists, a hypothesis receiving broad support in free-living species. Based on their niche breadth, parasites can also be classified as specialists and generalists, with specialists infecting only a few and generalists a diverse array of host species. Here, using avian haemosporidian parasites infecting wild bird populations inhabiting the Western Ghats, India as a model system, we elucidate how climate, habitat and human disturbance affects parasite prevalence both directly and indirectly via their effects on host diversity. Read More

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Bacteriophage Therapy for Critical and High-Priority Antibiotic-Resistant Bacteria and Phage Cocktail-Antibiotic Formulation Perspective.

Food Environ Virol 2021 Jun 12. Epub 2021 Jun 12.

Department of Biosciences, Manipal University Jaipur, Jaipur, Rajasthan, 303007, India.

Phage therapy is revolving to address the issues mainly dealing with antibiotic resistance in the pathogenic bacteria. Among the drug-resistant microbial populations, the bacterial species have been categorized as high-priority or critical-priority bacteria. This review summarizes the efficiency and development in phage therapy used against these drug-resistant bacteria in the past few years mainly belonging to the critical- and high-priority list. Read More

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Biological activities of two polypore macrofungi (Basidiomycota) and characterization of their compounds using HPLC-DAD and LC-ESI-MS/MS.

Folia Microbiol (Praha) 2021 Jun 13. Epub 2021 Jun 13.

Department of Chemical Technologies, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran.

Members of Hymenochaetaceae fungi are among well-known macromycetes with various medicinal properties. The aim of this study was to investigate the biological activities of Phellinus tuberculosus and Fuscoporia ferruginosa collected in Iran. The antimicrobial, antioxidant, and cytotoxic activities of the two species were examined, and their phenolic and polysaccharide contents were quantified. Read More

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Difference Between the Profiles Presented by Yeasts that Colonize the Vaginal Mucosa or Cause Primary or Recurrent Candidiasis.

Mycopathologia 2021 Jun 13. Epub 2021 Jun 13.

School of Dentistry, University of São Paulo (USP), Av. Lineu Prestes, 2.227, São Paulo, SP, 05508-000, Brazil.

Candida yeasts are the most frequent in the vaginal content. This yeast may be a normal microbiota but also causes candidiasis. In symptomatic cases, primary candidiasis (VVC) or recurrence (RVVC) can be considered. Read More

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A new fluorescent probe for neutral to alkaline pH and imaging application in live cells.

Spectrochim Acta A Mol Biomol Spectrosc 2021 May 27;261:120031. Epub 2021 May 27.

School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255049, PR China. Electronic address:

A new pH-sensitive fluorescent probe NAP-MDA was designed and synthesized. NAP-MDA consists of 1,8-naphthalimide as fluorophore, morpholine and N,N-dimethylethylenediamine as pH-responsive groups. Due to the photoinduced electron transfer (PET) mechanism, the fluorescence of 1, 8-naphthalimide was thoroughly quenched under alkaline condition (pH > 10. Read More

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Transcript level is a key factor affecting RNAi efficiency.

Pestic Biochem Physiol 2021 Jul 6;176:104872. Epub 2021 May 6.

The Key Laboratory of Monitoring and Management of Plant Diseases and Insects / Department of Entomology, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China. Electronic address:

Efficiency is the basis for the application of RNA interference (RNAi) technology. Actually, RNAi efficiency varies greatly among insect species, tissues and genes. Previous efforts have revealed the mechanisms for variation among insect species and tissues. Read More

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Effects of climate change factors on marine macroalgae: A review.

Yan Ji Kunshan Gao

Adv Mar Biol 2021 13;88:91-136. Epub 2020 Dec 13.

State Key Laboratory of Marine Environmental Science, Xiamen University/College of Ocean and Earth Sciences, Xiamen, China; Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang, China. Electronic address:

Marine macroalgae, the main primary producers in coastal waters, play important roles in the fishery industry and global carbon cycles. With progressive ocean global changes, however, they are increasingly exposed to enhanced levels of multiple environmental drivers, such as ocean acidification, warming, heatwaves, UV radiation and deoxygenation. While most macroalgae have developed physiological strategies against variations of these drivers, their eco-physiological responses to each or combinations of the drivers differ spatiotemporally and species-specifically. Read More

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December 2020

Comparison of four outdoor mosquito trapping methods as potential replacements for human landing catches in western Kenya.

Parasit Vectors 2021 Jun 12;14(1):320. Epub 2021 Jun 12.

PMI VectorLink Project, Abt Associates Inc., 6130 Executive Blvd, Rockville, MD, 20852, USA.

Introduction: Longitudinal monitoring of outdoor-biting malaria vector populations is becoming increasingly important in understanding the dynamics of residual malaria transmission. However, the human landing catch (HLC), the gold standard for measuring human biting rates indoors and outdoors, is costly and raises ethical concerns related to increased risk of infectious bites among collectors. Consequently, routine data on outdoor-feeding mosquito populations are usually limited because of the lack of a scalable tool with similar sensitivity to outdoor HLC. Read More

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Antimicrobial susceptibility of gram-positive and gram-negative bacteria: a 5-year retrospective analysis at a multi-hospital healthcare system in Saudi Arabia.

Ann Clin Microbiol Antimicrob 2021 Jun 12;20(1):43. Epub 2021 Jun 12.

College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

Background: Studying time-related changes in susceptible pathogens causing healthcare-associated infections (HAIs) is vital in improving local antimicrobial and infection control practices.

Objectives: Describe susceptibility patterns to several antimicrobials in gram-positive and gram-negative pathogens isolated from patients causing HAIs at three private tertiary care hospitals in Saudi Arabia over a 5-year period.

Methods: Data on trends of antimicrobial susceptibility among bacteria causing HAIs events in children and adults at three tertiary private hospitals located in Riyadh and Qassim, Saudi Arabia, were collected retrospectively between 2015 and 2019 using the surveillance data datasets. Read More

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Comparative analysis of alfalfa (Medicago sativa L.) seedling transcriptomes reveals genotype-specific drought tolerance mechanisms.

Plant Physiol Biochem 2021 May 29;166:203-214. Epub 2021 May 29.

Agricultural College, Ningxia University, Yinchuan, 750021, China. Electronic address:

Drought is one of the main abiotic factors that affect alfalfa yield. The identification of genes that control this complex trait can provide important insights for alfalfa breeding. However, little is known about how alfalfa responds and adapts to drought stress, particularly in cultivars of differing drought tolerance. Read More

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