318,009 results match your criteria southern


Systematic review of financial burden assessment in cancer: Evaluation of measures and utility among adolescents and young adults and caregivers.

Cancer 2021 Apr 13. Epub 2021 Apr 13.

Duke University School of Medicine & the Duke Cancer Institute, Durham, North Carolina.

The cost of cancer care is rising and represents a stressor that has significant and lasting effects on quality of life for many patients and caregivers. Adolescents and young adults (AYAs) with cancer are particularly vulnerable. Financial burden measures exist but have varying evidence for their validity and reliability. Read More

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Are survivors of cardiac arrest provided with standard cardiac rehabilitation? - Results from a national survey of hospitals and municipalities in Denmark.

Eur J Cardiovasc Nurs 2021 Apr;20(2):115-123

Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital and University of Southern Denmark, Odense, Denmark.

Aim: To quantify the provision of standard cardiac rehabilitation to Danish survivors of cardiac arrest at a programme level, and to analyse whether organizational factors influenced the provision.

Method: We mapped the provision of cardiac rehabilitation core components to survivors of cardiac arrest and compared this with a reference group of patients after acute myocardial infarction using data from a cross-sectional programme-level survey among all hospitals (n = 34) and municipalities (n = 98) in Denmark. Organizational factors of potential importance to service provision were considered: health care region, size of catchment area/population, type of department/municipality and socioeconomic index. Read More

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Environmental enrichment improves lifelong persistent behavioral and epigenetic changes induced by early-life stress.

J Psychiatr Res 2021 Apr 6;138:107-116. Epub 2021 Apr 6.

Translational Psychiatry Laboratory, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciuma, SC, Brazil. Electronic address:

This study aimed to evaluate the effects of environmental enrichment (EE) in Wistar rats subjected to maternal deprivation (MD). MD was performed in the first post-natal days (PND) ten for 3 h/day. The groups were: control; deprived without EE; and deprived with EE. Read More

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The fractionation of phosphorus in UK chalk stream surface waters and its relevance to the regulation and management of water quality.

J Environ Manage 2021 Apr 10;289:112555. Epub 2021 Apr 10.

School of Engineering, Faculty of Engineering & Physical Sciences, University of Southampton, Southampton Boldrewood Innovation Campus, Burgess Road, Southampton, SO16 7QF, UK.

The regulatory management of river water quality requires measurements of phosphorus that are operationally viable and meaningful in terms of insight into its effects. This need is a particular concern in globally rare and ecologically sensitive chalk streams. P data pertaining to rivers are commonly limited to soluble reactive P; other fractions of P may be of concern but are not routinely monitored. Read More

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Meta-analysis shows non-uniform responses of above- and belowground productivity to drought.

Sci Total Environ 2021 Apr 5;782:146901. Epub 2021 Apr 5.

Department of Ecology, Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, China. Electronic address:

Terrestrial productivity underpins ecosystem carbon (C) cycling and multi-trophic diversity. Despite the negative impacts of drought on terrestrial C cycling, our understanding of the responses of above- and belowground productivity to drought remains incomplete. Here, we synthesized the responses of terrestrial productivity and soil factors (e. Read More

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Low particulate nitrate in the residual layer in autumn over the North China Plain.

Sci Total Environ 2021 Apr 1;782:146845. Epub 2021 Apr 1.

State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China; Center for Excellence in Urban Atmospheric Environment, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

High ozone concentrations promote the formation of nitrate in the nocturnal residual layer (RL), but this phenomenon has not been confirmed by direct observation. In this study, ozone, water-soluble ions in PM and the corresponding meteorological factors in the stable boundary layer, RL and mixing layer were observed by portable instruments carried on a tethered balloon over the North China Plain. The ozone concentration significantly increased in the RL compared to that in the stable boundary layer, while particulate nitrate significantly decreased, except in the clouds. Read More

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In situ characterization of benthic fluxes and denitrification efficiency in a newly re-established mussel farm.

Sci Total Environ 2021 Apr 1;782:146853. Epub 2021 Apr 1.

Department of Marine Sciences, University of Gothenburg, Box 461, 405 30 Gothenburg, Sweden.

Mussel farming has been proposed as a mechanism to mitigate eutrophication in coastal waters. However, localizing the intensive filtration of organic matter by mussels can cause a concomitant enrichment of organic matter in sediments below farms, which may influence biogeochemical processes and fates of nutrients in the system. In the context of mitigating eutrophication, it is important to quantify sedimentary changes induced at early life stages of mussel farms. Read More

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Morphological and ecological responses of a managed coastal sand dune to experimental notches.

Sci Total Environ 2021 Apr 5;782:146813. Epub 2021 Apr 5.

Office National des Forêts, 75570 CEDEX 12 Paris, France. Electronic address:

In northern Europe, coastal dune remobilization by restoring natural processes is considered by some to maintain the coastal dune in chronically eroding sectors by migrating landward and to restore dune ecology. In wet climatic contexts, this nature-based solution has been shown to induce an increase in both sand bare areas and vegetation diversity. However, it has never been tested in the coastal dunes of southern Europe with a drier climate and, thus, more stressful conditions, where disturbance may inversely decrease vegetation diversity. Read More

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Efficacy of a water-based botanical acaricide formulation applied in portable spray box against the southern cattle tick, Rhipicephalus (Boophilus) microplus (Acari: Ixodidae), infesting cattle.

Ticks Tick Borne Dis 2021 Apr 3;12(4):101721. Epub 2021 Apr 3.

USDA-ARS, Knipling-Bushland U.S. Livestock Insects Research Laboratory, and Veterinary Pest Genomics Center, 2700 Fredericksburg Rd, Kerrville, TX, 78028, United States.

Ectoparasitism result in annual losses to livestock producers estimated to reach billions of dollars in tropical and subtropical parts of the world where the southern cattle tick, Rhipicephalus (Boophilus) microplus, is established because this invasive pest is also a vector of pathogens causing bovine babesiosis and anaplasmosis. Reintroduction of R. microplus could be economically devastating for the cattle industry in the United States. Read More

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Laparoscopic uterovaginal anastomosis in patients with congenital cervicovaginal atresia: An institutional experience with 23 patients.

Eur J Obstet Gynecol Reprod Biol 2021 Mar 31;260:218-224. Epub 2021 Mar 31.

Department of Obstetrics and Gynecology, The 3rd Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, 518000, PR China.

Objective: To introduce our experience of laparoscopic uterovaginal anastomosis and operative outcomes following this technique and update the clinical management of congenital cervicovaginal atresia.

Study Design: Between March 2015 and January 2019, twenty-three patients with congenital cervicovaginal atresia underwent laparoscopic uterovaginal anastomosis and Luohu procedure. Their clinical characteristics, surgical outcomes and follow-up data were retrospectively reviewed. Read More

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Spleen and lung virome analysis of South American fur seals (Arctocephalus australis) collected on the southern Brazilian coast.

Infect Genet Evol 2021 Apr 10:104862. Epub 2021 Apr 10.

Laboratório de Virologia, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil. Electronic address:

South American fur seals (Arctocephalus australis) are believed to reach the coast of Rio Grande do Sul (RS) through sea currents. They live in colonies and are frequently found resting on the beach. However, it is also common to find dead pinnipeds on beaches, sharing the environment with humans, domestic animals and other wild species on the coast and facilitating the transmission of pathogens. Read More

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Multi-omics analysis of the prognosis and therapeutic significance of circadian clock in ovarian cancer.

Gene 2021 Apr 10:145644. Epub 2021 Apr 10.

Department of Gynecology, Southern Medical University Affiliated Maternal & Child Health Hospital of Foshan, Foshan, Guangdong, 528000, China. Electronic address:

Ovarian cancer (OV) is one of the most common female malignancies with high morbidity and mortality, but its mechanism is not fully understood. The circadian clock is involved in the regulation of the immune system and the tumor microenvironment, regulating biological processes and behaviors in multiple ways. Circadian rhythm disorders are considered a risk factor for tumorigenesis. Read More

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Evolution of the gross tumour volume extent during radiotherapy for glioblastomas.

Radiother Oncol 2021 Apr 10. Epub 2021 Apr 10.

Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Department of Oncology, Odense University Hospital, Odense, Denmark.

Background And Purpose: Tumour growth during radiotherapy may lead to geographical misses of the target volume. This study investigates the evolution of the tumour extent and evaluates the need for plan adaptation to ensure dose coverage of the target in glioblastoma patients.

Materials And Methods: The prospective study included 29 patients referred for 59. Read More

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Chronic high risk of intimate partner violence against women in disadvantaged neighborhoods: An eight-year space-time analysis.

Prev Med 2021 Apr 10:106550. Epub 2021 Apr 10.

Department of Social Psychology, University of Valencia, Av. Blasco Ibáñez, 21, 46010, Valencia, Spain.

We conducted a small-area ecological longitudinal study to analyze neighborhood contextual influences on the spatio-temporal variations in intimate partner violence against women (IPVAW) risk in a southern European city over an eight-year period. We used geocoded data of IPVAW cases with associated protection orders (n = 5867) in the city of Valencia, Spain (2011-2018). The city's 552 census block groups were used as the neighborhood units. Read More

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FDA-approved 5-HT receptor agonist lasmiditan induces mitochondrial biogenesis and enhances locomotor and blood-spinal cord barrier recovery after spinal cord injury.

Exp Neurol 2021 Apr 10:113720. Epub 2021 Apr 10.

Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ, United States of America; Department of Neurosciences, College of Medicine, University of Arizona, Tucson, AZ, United States of America; College of Pharmacy, University of Arizona, Tucson, AZ, United States of America; Southern Arizona VA Health Care System, Tucson, AZ, United States of America; Southwest Environmental Health Science Center, University of Arizona, Tucson, AZ, United States of America; Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, United States of America. Electronic address:

Vascular and mitochondrial dysfunction are well-established consequences of spinal cord injury (SCI). Evidence suggests mitigating these dysfunctions may be an effective approach in treating SCI. The goal of this study was to elucidate if mitochondrial biogenesis (MB) induction with a new, selective and FDA-approved 5-hydroxytryptamine receptor 1F (5-HT) receptor agonist, lasmiditan, can stimulate locomotor recovery and restoration of the blood-spinal cord barrier (BSCB) after SCI. Read More

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Early stem cell aging in the mature brain.

Cell Stem Cell 2021 Apr 7. Epub 2021 Apr 7.

Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research at USC, University of Southern California, Los Angeles, CA 90033, USA; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90033, USA; USC Davis School - Buck Institute Graduate Program in the Biology of Aging, University of Southern California, Los Angeles, CA 90033, USA; Neuroscience Graduate Program, W. M. Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90033, USA; Davis School of Gerontology, University of Southern California, Los Angeles, CA 90033, USA. Electronic address:

Stem cell dysfunction drives many age-related disorders. Identifying mechanisms that initially compromise stem cell behavior represent early targets to promote tissue function later in life. Here, we pinpoint multiple factors that disrupt neural stem cell (NSC) behavior in the adult hippocampus. Read More

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Is all activity equal? Associations between different domains of physical activity and depressive symptom severity among 261,121 European adults.

Depress Anxiety 2021 Apr 13. Epub 2021 Apr 13.

Physically Active Lifestyles Research Group (USQ-PALs), Institute for Resilient Regions, Center for Health Research, University of Southern Queensland, Toowoomba, Australia.

Background: Physical activity is often associated with better mental health. However, there is evidence that the domain of physical activity influences the strength and direction of this association. Therefore, this study aimed to examine the associations between different domains of physical activity and depression among a large sample of adults living in the European Union. Read More

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Comparative study of neuroendocrine acquisition and biomarker expression between neuroendocrine and usual prostatic carcinoma.

Prostate 2021 Apr 13. Epub 2021 Apr 13.

Department of Pathology, LAC+USC and Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Background: Neuroendocrine prostatic carcinoma (NEPC) is uncommon. The pathogenesis, clinical association, and clinical implications of this disease are still evolving.

Methods: Clinicopathologic, immunohistochemical and genomic studies were used to investigate the incidence of NEPC in various clinicopathologic settings and the expression of various biomarkers in NEPC and non-NEPC as well as small cell NEPC. Read More

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In vivo FRET-FLIM reveals ER-specific increases in the ABA level upon environmental stresses.

Plant Physiol 2021 Apr 12. Epub 2021 Apr 12.

Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, Department of Biology, School of Life Science, Southern University of Science and Technology, Shenzhen 518055, China.

Plant hormone abscisic acid (ABA) is essential for regulating plant growth and various stress responses. ABA-mediated signaling depends on local ABA levels rather than overall cellular ABA concentration. Whereas cellular concentration of ABA can be detected using Förster resonance energy transfer (FRET)-based ABA probes, direct imaging of subcellular ABA levels remains unsolved. Read More

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Serial intravital imaging captures dynamic and functional endothelial remodeling with single-cell resolution.

JCI Insight 2021 Apr 13. Epub 2021 Apr 13.

Department of Physiology and Neuroscience, University of Southern California, Los Angeles, United States of America.

Endothelial cells are important in the maintenance of healthy blood vessels and in the development of vascular diseases. However, the origin and dynamics of endothelial precursors and remodeling at the single-cell level have been difficult to study in vivo due to technical limitations. We aimed to develop a direct visual approach to track the fate and function of single endothelial cells over several days-weeks in the same vascular bed in vivo using multiphoton microscopy (MPM) of transgenic Cdh5-Confetti mice and the kidney glomerulus as a model. Read More

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Targeted Wellness Initiatives Are Most Effective for Reducing Otolaryngology Resident Burnout.

Ear Nose Throat J 2021 Apr 13:1455613211009139. Epub 2021 Apr 13.

USC Caruso Department of Otolaryngology, Head and Neck Surgery, University of Southern California, Los Angeles, CA, USA.

Objective: Investigate the effect of a targeted wellness program on burnout in Otolaryngology residents.

Methods: Residents and faculty collaboratively developed a program aimed at improving resident wellness. Program implementation began in July of 2018 and after 1 year, residents evaluated the program's effects on burnout. Read More

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Control the Neural Stem Cell Fate with Biohybrid Piezoelectrical Magnetite Micromotors.

Nano Lett 2021 Apr 13. Epub 2021 Apr 13.

School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou 510275, China.

Inducing neural stem cells to differentiate and replace degenerated functional neurons represents the most promising approach for neural degenerative diseases including Parkinson's disease, Alzheimer's disease, etc. While diverse strategies have been proposed in recent years, most of these are hindered due to uncontrollable cell fate and device invasiveness. Here, we report a minimally invasive micromotor platform with biodegradable helical () as the framework and superparamagnetic FeO nanoparticles/piezoelectric BaTiO nanoparticles as the built-in function units. Read More

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Hollow Spherical Superstructure of Carbon Nanosheets for Bifunctional Oxygen Reduction and Evolution Electrocatalysis.

Nano Lett 2021 Apr 13. Epub 2021 Apr 13.

AIST-Kyoto University Chemical Energy Materials Open Innovation Laboratory (ChEM-OIL), National Institute of Advanced Industrial Science and Technology (AIST), Sakyo-ku, Kyoto 606-8501, Japan.

The pyrolysis of metal-organic frameworks (MOFs) is an ingenious way to synthesize carbon-based materials with unique morphology for various applications including electrocatalysis. In this work, we reported a facile morphology regulation strategy for the synthesis of a spherical superstructure of MOF nanosheets. The use of metal hydroxide nanosheets on Zn particles as precursors/templates allowed MOFs with general polyhedron shape to form nanosheets and assemble into a spherical superstructure in the ligand solution. Read More

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Hierarchical Self-Assembly of Nanowires on the Surface by Metallo-Supramolecular Truncated Cuboctahedra.

J Am Chem Soc 2021 Apr 13. Epub 2021 Apr 13.

College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China.

Parastichy, the spiral arrangement of plant organs, is an example of the long-range apparent order seen in biological systems. These ordered arrangements provide scientists with both an aesthetic challenge and a mathematical inspiration. Synthetic efforts to replicate the regularity of parastichy may allow for molecular-scale control over particle arrangement processes. Read More

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Genomic and transcriptomic insights into the habitat adaptation of the diazotrophic paddy-field cyanobacterium Nostoc sphaeroides.

Environ Microbiol 2021 Apr 13. Epub 2021 Apr 13.

School of Life Sciences, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan, Hubei, 430079, China.

Nitrogen-fixing cyanobacteria are common in paddy fields, one of the most productive wetland ecosystems. Here, we present the complete genome of Nostoc sphaeroides, a paddy-field diazotroph used for food and medicine for more than 1700 years and deciphered the transcriptional regulation during the developmental transition from hormogonia to vegetative filaments with heterocysts. The genome of N. Read More

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Open Dialogue, need-adapted mental health care, and implementation fidelity: A discussion paper.

Int J Ment Health Nurs 2021 Apr 13. Epub 2021 Apr 13.

The Centre for Family-Based Mental Health Care, St. Vincent's Private Hospital, Darlinghurst, New South Wales, Australia.

Open Dialogue is a need-adapted approach to mental health care that was originally developed in Finland. Like other need-adapted approaches, Open Dialogue aims to meet consumer's needs and promote collaborative person-centred dialogue to support recovery. Need-adapted mental health care is distinguished by flexibility and responsiveness. Read More

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Multidisciplinary telephone conferences about medication therapy after discharge of older inpatients: a feasibility study.

Int J Clin Pharm 2021 Apr 13. Epub 2021 Apr 13.

Hospital Pharmacy Funen, Odense University Hospital, Solfaldsvej 38, 5000, Odense C, Denmark.

Background Studies have shown poor post-discharge implementation by the general practitioner of changes made to patients' medication during admission. Objective To assess the feasibility of conducting telephone conferences delivering information about changes in older patients' medications from hospital to general practitioners. Setting Two departments of geriatric medicine in a Danish routine healthcare setting. Read More

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The forensic landscape and the population genetic analyses of Hainan Li based on massively parallel sequencing DNA profiling.

Int J Legal Med 2021 Apr 13. Epub 2021 Apr 13.

School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, China.

Due to the formation of the Qiongzhou Strait by climate change and marine transition, Hainan island was isolated from the mainland southern China during the Last Glacial Maximum. Hainan island, located at the southernmost part of China and separated from the Leizhou Peninsula by the Qiongzhou Strait, laid on one of the modern human northward migration routes from Southeast Asia to East Asia. The Hlai language-speaking Li minority, the second largest population after Han Chinese in Hainan island, is the direct descendants of the initial migrants in Hainan island and has unique ethnic properties and derived characteristics; however, the forensic-associated studies on Hainan Li population are still insufficient. Read More

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Mitigating the stress response to improve outcomes for older patients undergoing emergency surgery with the addition of beta-adrenergic blockade.

Eur J Trauma Emerg Surg 2021 Apr 13. Epub 2021 Apr 13.

University of Southern California, Los Angeles, USA.

As population age, healthcare systems and providers are likely to experience a substantial increase in the proportion of elderly patients requiring emergency surgery. Emergency surgery, compared with planned surgery, is strongly associated with increased risks of adverse postoperative outcomes due to the short time available for diagnosis, optimization, and intervention in patients presenting with physiological derangement. These patient populations, who are often frail and burdened with a variety of co-morbidities, have lower reserves to deal with the stress of the acute condition and the required emergency surgical intervention. Read More

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Acute retrobulbar optic neuritis with anti-myelin oligodendrocyte glycoprotein antibody-associated disease complicated with microscopic polyangiitis: A case report.

Medicine (Baltimore) 2021 Apr;100(15):e24889

Department of Rheumatology.

Rationale: Anti-myelin oligodendrocyte protein antibody-associated disease (MOGAD) is a new disease entity with various clinical phenotypes. MOGAD often present with recurrent optic neuritis (ON), and it can also develop as a compartment of neuromyelitis optica spectrum disorder (NMOSD). Moreover, multiple autoantibodies such as an anti-myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) had been reported in the serum of patients with NMOSD. Read More

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