644 results match your criteria source antibiotic-resistant


An assessment of resistome and mobilome in wastewater treatment plants through temporal and spatial metagenomic analysis.

Water Res 2021 Nov 22;209:117885. Epub 2021 Nov 22.

Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering, The University of Hong Kong, Hong Kong, China. Electronic address:

Wastewater treatment plants (WWTPs) are regarded as critical points in disseminating antibiotic resistance genes (ARGs). In particular, the discharging effluents from WWTPs generally bring downstream catchment areas exogenous ARGs and resistant bacteria. However, there lacks a sufficient assessment of the resistome and mobilome in effluents. Read More

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November 2021

Molecular characterization of isolated from milk samples with regard to virulence factors and antibiotic resistance.

Vet World 2021 Sep 17;14(9):2410-2418. Epub 2021 Sep 17.

Department of Microbiology, Faculty of Veterinary Medicine, South Valley University, Qena, 83523, Egypt.

Background And Aim: Raw milk is considered an essential source of nutrition during all stages of human life because it offers a valuable supply of protein and minerals. Importantly, milk is considered a good media for the growth and contamination of many pathogenic bacteria, especially food-borne pathogens such as . Thus, the objective of this study was to characterize and detect its virulence factors and antibiotic resistance from raw milk samples. Read More

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September 2021

The dynamic of the potential pathogenic bacteria, antibiotic-resistant bacteria, and antibiotic resistance genes in the water at different growth stages of grass carp pond.

Environ Sci Pollut Res Int 2021 Nov 24. Epub 2021 Nov 24.

University Joint Laboratory of Guangdong Province, Hong Kong and Macao Region on Marine Bioresource Conservation and Exploitation, Guangdong Laboratory for Lingnan Modern Agriculture, College of Marine Sciences, South China Agricultural University, Guangzhou, 510642, China.

Pond aquaculture has become the most important and broadest breeding model in China, and an extremely important source of aquatic products, but the potential hazard factors of potential pathogenic bacteria (PPB), antibiotic resistance bacteria (ARB), and antibiotic resistance genes (ARGs) in aquaculture environment are largely invisible. In the present study, the bacterial communities in the larvae, juvenile, rearing, and harvesting culture stages of great grass carp (Ctenopharyngodon idellus) ponds were investigated and the structure of microbial flora analysis showed that the larvae culture stage has the highest abundance and the most dominant phyla were Proteobacteria (27.8%). Read More

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November 2021

Trends, relationships and case attribution of antibiotic resistance between children and environmental sources in rural India.

Sci Rep 2021 Nov 19;11(1):22599. Epub 2021 Nov 19.

Department of Global Public Health, Health Systems and Policy (HSP): Improving Use of Medicines, Karolinska Institutet, 171 77, Stockholm, Sweden.

Bacterial antibiotic resistance is an important global health threat and the interfaces of antibiotic resistance between humans, animals and the environment are complex. We aimed to determine the associations and overtime trends of antibiotic resistance between humans, animals and water sources from the same area and time and estimate attribution of the other sources to cases of human antibiotic resistance. A total of 125 children (aged 1-3 years old) had stool samples analysed for antibiotic-resistant bacteria at seven time points over two years, with simultaneous collection of samples of animal stools and water sources in a rural Indian community. Read More

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November 2021

The air-borne antibiotic resistome: Occurrence, health risks, and future directions.

Sci Total Environ 2022 Jan 6;804:150154. Epub 2021 Sep 6.

Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Antibiotic resistance comprising of antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) is an emerging problem causing global human health risks. Several reviews exist on antibiotic resistance in various environmental compartments excluding the air-borne resistome. An increasing body of recent evidence exists on the air-borne resistome comprising of antibiotic resistance in air-borne bioaerosols from various environmental compartments. Read More

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January 2022

Biochemical and study of leaf and bark extracts from against common pathogenic bacteria.

Saudi J Biol Sci 2021 Nov 16;28(11):6592-6605. Epub 2021 Jul 16.

Microbiology Laboratory, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi 6205, Bangladesh.

may be a natural, renewable resource against antibiotic-resistant bacterial infections. The antibacterial activity of leaf and bark extracts was investigated against three antibiotic-resistant bacterial species and one fungus. Methanolic leaf extract showed only limited antibacterial activity but both methanolic and aqueous bark extract showed high antimicrobial activity. Read More

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November 2021

Antibiotic resistance and phylogenetic comparison of human, pet animals and raw milk Staphylococcus aureus isolates.

Comp Immunol Microbiol Infect Dis 2021 Oct 28;79:101717. Epub 2021 Oct 28.

Department of Microbiology, College of Science, Agriculture and Modern Technology, Shiraz branch, Islamic Azad University, Shiraz, Iran.

The present study was conducted to compare the S. aureus isolates from different sources in the basis of resistance phenotypic and genotypic features and phylogenetic differences. Total of 70 S. Read More

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October 2021

Analysing the fitness cost of antibiotic resistance to identify targets for combination antimicrobials.

Nat Microbiol 2021 Nov 25;6(11):1410-1423. Epub 2021 Oct 25.

Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.

Mutations in the rifampicin (Rif)-binding site of RNA polymerase (RNAP) confer antibiotic resistance and often have global effects on transcription that compromise fitness and stress tolerance of resistant mutants. We suggested that the non-essential genome, through its impact on the bacterial transcription cycle, may represent an untapped source of targets for combination antimicrobial therapies. Using transposon sequencing, we carried out a genome-wide analysis of fitness cost in a clinically common rpoB H526Y mutant. Read More

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November 2021

Antimicrobial resistance and genetic diversity of Enterococcus faecalis from yolk sac infections in broiler chicks.

Poult Sci 2021 Dec 17;100(12):101491. Epub 2021 Sep 17.

Department of Pharmaceutical Microbiology, Medical University in Lublin, Lublin, 20-093 Poland.

Despite restrictions on the use of antibiotics in poultry, the percentage of multidrug resistant bacteria, isolated from both adult birds and chicks, remains high. These bacteria can spread between countries via hatching eggs or chicks. Antibiotic resistant bacteria can also pose a threat to hatchery and farm workers or to consumers of poultry. Read More

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December 2021

Exploration of the Pharmacodynamics for Biofilm Eradication by Tobramycin.

Antimicrob Agents Chemother 2021 Oct 25:AAC0137121. Epub 2021 Oct 25.

Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA.

is a Gram-negative, opportunistic pathogen which is involved in numerous infections. It is of growing concern within the field of antibiotic resistant and tolerance and often exhibits multi-drug resistance. Previous studies have shown the emergence of antibiotic resistant and tolerant variants within the zone of clearance of a biofilm lawn after exposure to aminoglycosides. Read More

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October 2021

Looking Back to : History of the Antibiotic Discovery and Future Prospects.

Antibiotics (Basel) 2021 Oct 15;10(10). Epub 2021 Oct 15.

Gause Institute of New Antibiotics, 119021 Moscow, Russia.

The emergence of antibiotic-resistant pathogenic bacteria in recent decades leads us to an urgent need for the development of new antibacterial agents. The species of the genus are known as producers of secondary metabolites that are used in medicine and agriculture. The complete genome sequences of the demonstrate a wide variety of biosynthetic gene clusters, which highlights the potential ability of actinomycetes of this genus to produce new antibiotics. Read More

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October 2021

Novel amylomacins from seaweed-associated Bacillus amyloliquefaciens as prospective antimicrobial leads attenuating resistant bacteria.

World J Microbiol Biotechnol 2021 Oct 19;37(12):200. Epub 2021 Oct 19.

Crustacean Fisheries Division, Central Marine Fisheries Research Institute, Ernakulam North, P.B. No. 1603, Cochin, India.

The rise in antibiotic-resistant bacterial strains prompting nosocomial infections drives the search for new bioactive substances of promising antibacterial properties. The surfaces of seaweeds are rich in heterotrophic bacteria with prospective antimicrobial substances. This study aimed to isolate antibacterial leads from a seaweed-associated bacterium. Read More

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October 2021

Antibiotic resistance patterns of Escherichia coli isolates from the clinic through the wastewater pathway.

Int J Hyg Environ Health 2021 09 16;238:113863. Epub 2021 Oct 16.

Department of Biomedical Sciences, College of Health Sciences, University of Wisconsin - Milwaukee, Milwaukee, WI, 53211, USA. Electronic address:

Antimicrobial resistance (AMR) remains one of the leading global health threats. This study compared antimicrobial resistance patterns among E. coli isolates from clinical uropathogenic Escherichia coli (UPEC) to hospital wastewater populations and throughout an urban wastewater treatment facility - influent, pre- and post-chlorinated effluents. Read More

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September 2021

Persisting antibiotic resistance gene pollution and its association with human sewage sources in tropical marine beach waters.

Int J Hyg Environ Health 2021 09 14;238:113859. Epub 2021 Oct 14.

Research Laboratory of Biotechnology, Chulabhorn Research Institute, Bangkok, 10210, Thailand; Center of Excellence on Environmental Health and Toxicology EHT, Ministry of Education, Bangkok, 10400, Thailand. Electronic address:

Antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) are pollutants of worldwide concern that threaten human health and ecosystems. Anthropogenic activities and wastewater could be ARB and ARG pollution sources; however, research on ARG abundance and microbial source tracking (MST) of contamination in tropical marine waters is limited. This study examined spatiotemporal variations of six ARGs (bla, bla, bla, mcr-1, sul1, and tetQ) against the widely used antibiotic groups and a class 1 integron-integrase gene (intI1) at two Thai tropical recreational beaches (n = 41). Read More

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September 2021

Honey and Its Antimicrobial Properties: A Function of a Single Component, or the Sum of Its Parts?

Cureus 2021 Sep 4;13(9):e17718. Epub 2021 Sep 4.

Medicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.

Introduction: Honey is known for exhibiting antibacterial properties, indicating its use as part of traditional medicine since the early ages. With the advent of antibiotic-resistant bacteria, the need for alternative antimicrobials has outpaced the actual development of novel, broad-spectrum antibiotics. Previous research has revolved around the sugar content of honey because its sweetness makes it an attractive food source. Read More

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September 2021

Microbial colonization and resistome dynamics in food processing environments of a newly opened pork cutting industry during 1.5 years of activity.

Microbiome 2021 10 14;9(1):204. Epub 2021 Oct 14.

Department of Food Hygiene and Technology, Universidad de León, León, Spain.

Background: The microorganisms that inhabit food processing environments (FPE) can strongly influence the associated food quality and safety. In particular, the possibility that FPE may act as a reservoir of antibiotic-resistant microorganisms, and a hotspot for the transmission of antibiotic resistance genes (ARGs) is a concern in meat processing plants. Here, we monitor microbial succession and resistome dynamics relating to FPE through a detailed analysis of a newly opened pork cutting plant over 1. Read More

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October 2021

DNA vaccine containing gene induces significant immune responses against infection: An study.

Iran J Basic Med Sci 2021 Jun;24(6):796-804

Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Objectives: is one of the most prevalent human infectious agents that is directly involved in various upper digestive tract diseases. Although antibiotics-based therapy and proton pump inhibitors eradicate the bacteria mostly, their effectiveness has been declined recently due to emergence of antibiotic-resistant strains. Development of a DNA vaccine is a promising approach against bacterial pathogens. Read More

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Salted duck eggs: the source for pathogens and antibiotic resistant bacteria.

J Food Sci Technol 2021 Dec 12;58(12):4722-4729. Epub 2021 Jan 12.

School of Life Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, 619 Changcheng Rd., Tai'an, Shandong Province China.

Salted duck eggs as a convenient food are very popular in China and Southeast Asia. Generally, they are produced by traditional curing methods. Here we used traditional methods to profile the bacterial community of salted duck eggs purchased from markets to systematically investigate their microbiological safety. Read More

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December 2021

Silver Decorated Myconanoparticles Control Growth and Biofilm Formation in Uropathogenic E. coli.

Appl Biochem Biotechnol 2021 Oct 7. Epub 2021 Oct 7.

School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Chennai, 600048, India.

Nanotechnology involves the synthesis of nanoparticles that have been used in the therapeutic application for treating diseases. In this present study, we have adopted the synthesis of myconanoparticles from the extracellular extract of endophytic fungi Penicillium sclerotiorum (PsNps) and validated its antibacterial potential against antibiotic-resistant uropathogenic E. coli and ATCC (25,922) strain of Escherichia coli. Read More

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October 2021

Migratory birds travelling to Bangladesh are potential carriers of multi-drug resistant spp., spp., and spp.

Saudi J Biol Sci 2021 Oct 24;28(10):5963-5970. Epub 2021 Jun 24.

Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.

Antimicrobial resistance (AMR) is a major health crisis globally. Migratory birds could be a potential source for antibiotic resistant (ABR) bacteria. Not much is known about their role in the transmission of ABR in Bangladesh. Read More

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October 2021

Impact of biosolids amendment and wastewater effluent irrigation on enteric antibiotic-resistant bacteria - a greenhouse study.

Water Res X 2021 Dec 8;13:100119. Epub 2021 Sep 8.

School of Chemical, Biological, and Environmental Engineering, Oregon State University, 105 SW 26th St, 116 Johnson Hall, Corvallis, OR 97331, United States.

Reuse of wastewater effluent and biosolids in agriculture is essential to sustainable water and nutrient resource management practices. Wastewater and biosolids, however, are reportedly the recipients, reservoirs, and sources of antibiotic-resistant enteric pathogens. While decay rates of fecal bacterial indicators in soil are frequently studied, very few studies have reported on the persistence of the antibiotic-resistant sub-populations. Read More

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December 2021

Hospital Wastewater-Source of Specific Micropollutants, Antibiotic-Resistant Microorganisms, Viruses, and Their Elimination.

Antibiotics (Basel) 2021 Sep 4;10(9). Epub 2021 Sep 4.

Department of Nutrition and Food Quality Assessment, Faculty of Chemical and Food Technology STU, Slovak University of Technology in Bratislava, Radlinského 9, 812 37 Bratislava, Slovakia.

Municipal wastewaters can generally provide real-time information on drug consumption, the incidence of specific diseases, or establish exposure to certain agents and determine some lifestyle consequences. From this point of view, wastewater-based epidemiology represents a modern diagnostic tool for describing the health status of a certain part of the population in a specific region. Hospital wastewater is a complex mixture of pharmaceuticals, illegal drugs, and their metabolites as well as different susceptible and antibiotic-resistant microorganisms, including viruses. Read More

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September 2021

Isolation and characterization of a heavy metal- and antibiotic-tolerant novel bacterial strain from a contaminated culture plate of , a green micro-alga.

F1000Res 2021 5;10:533. Epub 2021 Jul 5.

Department of Mathematics, Sciences and Technology, University of West Georgia, Carrollton, Georgia, 30118, USA.

, a green micro-alga, is normally cultured in laboratories in Tris-Acetate Phosphate (TAP), a medium which contains acetate as the sole carbon source. Acetate in TAP can lead to occasional bacterial and fungal contamination. We isolated a yellow-pigmented bacterium from a TAP plate. Read More

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October 2021

Enhanced clearing of biofilms on a 3D urothelial cell model using lysozyme-functionalized fluconazole-loaded shellac nanoparticles.

Biomater Sci 2021 Oct 12;9(20):6927-6939. Epub 2021 Oct 12.

Department of Chemistry, Nazarbayev University, 53 Kabanbay Batyr Avenue, Nursultan city, 010000, Kazakhstan.

urinary tract biofilms are increasingly witnessed in nosocomial infections due to reduced immunity of patients and the hospital ecosystem. The indwelling devices utilized to support patients with urethral diseases that connect the unsterilized external environment with the internal environment of the patient are another significant source of urinary tract biofilm infections. Recently, nanoparticle (NP)-associated therapeutics have gained traction in a number of areas, including fighting antibiotic-resistant bacterial biofilm infection. Read More

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October 2021

Manipulating turn residues on de novo designed β-hairpin peptides for selectivity against drug-resistant bacteria.

Acta Biomater 2021 11 8;135:214-224. Epub 2021 Sep 8.

Department of Pharmacy, National University of Singapore, 117543, Singapore, Singapore; NUS Graduate School for Integrative Sciences and Engineering, 119077, Singapore, Singapore. Electronic address:

Synthetic β-hairpin antimicrobial peptides (AMPs) offer a useful source for the development of novel antimicrobial agents. β-hairpin peptides generally consist of two side strands bridged by a reverse turn. In literature, most studies focused on the modifications of the side strands to manipulate the stability and activity of β-hairpin peptides, and much less is known about the impact of the turn region. Read More

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November 2021

Metagenomic Analysis of Antibiotic Resistance Genes in Untreated Wastewater From Three Different Hospitals.

Front Microbiol 2021 24;12:709051. Epub 2021 Aug 24.

School of Pharmacy, Southwest Medical University, Luzhou, China.

Controlling antibiotic resistance genes (ARGs) is a worldwide intervention to ensure global health. Hospital wastewater is the main pollution source of antibiotic-resistant bacteria and ARGs in the environment. Expanding our knowledge on the bacterial composition of hospital wastewater could help us to control infections in hospitals and decrease pathogen release into the environment. Read More

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Bacteriophage endolysins against gram-positive bacteria, an overview on the clinical development and recent advances on the delivery and formulation strategies.

Crit Rev Microbiol 2021 Sep 3:1-24. Epub 2021 Sep 3.

School of Pharmacy, The Chinese University of Hong Kong, Hong Kong, China.

Facing the increasing threat of multi-drug antimicrobial resistance (AMR), humans strive to search for antibiotic drug candidates and antibacterial alternatives from all possible places, from soils in remote areas to deep in the sea. In this "gold rush for antibacterials," researchers turn to the natural enemy of bacterial cells, bacteriophage (phages), and find them a rich source of weapons for AMR bacteria. Endolysins (lysins), the enzymes phages use to break the bacterial cells from within, have been shown to be highly selective and efficient in killing their target bacteria from outside while maintaining a low occurrence of bacterial resistance. Read More

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September 2021

Antibiotic resistance of culturable heterotrophic bacteria isolated from shrimp (Penaeus vannamei) aquaculture ponds.

Mar Pollut Bull 2021 Nov 24;172:112887. Epub 2021 Aug 24.

MFB Division, ICAR-Central Institute of Fisheries Technology, Willingdon Island, Matsyapuri P.O., Cochin 682029, Kerala, India. Electronic address:

Shrimp aquaculture is one of the fastest growing food-producing avenues, where antibiotics usage has become an issue of great concern due to the development of antimicrobial resistance in bacteria. A total of 2304 bacterial isolates from 192 samples (sediment, water, shrimp, and source water) from Andhra Pradesh, India were screened. Antibiotic resistance of bacterial isolates was highest for oxytetracycline (23. Read More

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November 2021

Review on the Antibacterial Mechanism of Plant-Derived Compounds against Multidrug-Resistant Bacteria (MDR).

Evid Based Complement Alternat Med 2021 16;2021:3663315. Epub 2021 Aug 16.

Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul, Turkey.

Microbial resistance has progressed rapidly and is becoming the leading cause of death globally. The spread of antibiotic-resistant microorganisms has been a significant threat to the successful therapy against microbial infections. Scientists have become more concerned about the possibility of a return to the pre-antibiotic era. Read More

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Phytoplankton of the Curonian Lagoon as a New Interesting Source for Bioactive Natural Products. Special Impact on Cyanobacterial Metabolites.

Biomolecules 2021 08 2;11(8). Epub 2021 Aug 2.

Division of Marine Biotechnology, Faculty of Oceanography and Geography, University of Gdańsk, Marszałka J. Piłsudskiego 46, PL-81378 Gdynia, Poland.

The bioprospecting of marine and brackish water systems has increased during the last decades. In this respect, microalgae, including cyanobacteria, and their metabolites are one of the most widely explored resources. Most of the bioactive compounds are isolated from ex situ cultures of microorganisms; however, analysis of field samples could also supply valuable information about the metabolic and biotechnological potential of microalgae communities. Read More

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