44,055 results match your criteria society children


Transcriptional regulation of the basic helix-loop-helix factor AmeloD during tooth development.

J Cell Physiol 2021 Apr 12. Epub 2021 Apr 12.

Department of Oral Health and Development Sciences, Division of Pediatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.

The epithelial-mesenchymal interactions are essential for the initiation and regulation of the development of teeth. Following the initiation of tooth development, numerous growth factors are secreted by the dental epithelium and mesenchyme that play critical roles in cellular differentiation. During tooth morphogenesis, the dental epithelial stem cells differentiate into several cell types, including inner enamel epithelial cells, which then differentiate into enamel matrix-secreting ameloblasts. Read More

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The association between imbalances in vaginal microflora and duration of pregnancy as well as selected maternal and neonatal parameters.

Ginekol Pol 2021 Apr 12. Epub 2021 Apr 12.

Department of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, Poland.

Objectives: Abnormal vaginal flora (AVF) is a result of excessive growth of some aerobic bacteria and fungi in relation to the scarce presence of Lactobacillus spp. It has been suggested that AVF is responsible for preterm birth and such neonatal conditions as infections or sepsis. The aim of the study was to assess the influence of excessive vaginal colonization with aerobic bacteria and fungi on the selected postnatal parameters of newborns, duration of pregnancy and length of hospitalisation of neonates. Read More

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The Urogynecology Section of the Polish Society of Gynecologists and Obstetricians guidelines on the management of non-neurogenic overactive bladder syndrome in women.

Ginekol Pol 2021 ;92(3):236-251

Department of Operative Gynecology and Gynecologic Oncology, I Department of Gynecology and Obstetrics, Medical University of Lodz, Poland.

Objectives: The aim of the publication was to present the interdisciplinary guidelines of the Urogynecology Section of the Polish Society of Gynecologists and Obstetricians (PSGO) for the treatment of overactive bladder (OAB) syndrome based on the available literature, expert knowledge, and everyday practice.

Material And Methods: A review of the literature, including current recommendations for the treatment of overactive bladder syndrome, urinary incontinence, urgency and mixed urinary incontinence, as well as the earlier recommendations of the PSGO Urogynecology Section, was conducted.

Results: Management of the patients with OAB is presented. Read More

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January 2021

The Urogynecology Section of the Polish Society of Gynecologists and Obstetricians Guideline on the use of urodynamic testing in gynecological practice.

Ginekol Pol 2021 ;92(3):230-235

Department of Operative Gynecology and Gynecological Oncology, I Department of Gynecology and Obstetrics, Medical University of Lodz, Poland.

Objectives: The aim was to present an interdisciplinary Guideline of the Urogynecology Section of the Polish Society of Gynecologists and Obstetricians (PSGO) for the use of urodynamics (UDS) in the diagnostic process of patients with lower urinary tract symptoms (LUTS) based on the available literature, expert knowledge, and everyday practice.

Material And Methods: A review of the literature concerning the use of UDS in women, including current international guidelines and earlier recommendations of the PSGO Urogynecology Section, was conducted.

Results: Urodynamic testing allows to make the urodynamic diagnosis which, nevertheless, remains to be the preliminary diagnosis. Read More

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January 2021

Comparison of Clinical Outcomes Between Chinese Patients Receiving Hepatectomy With or Without Enhanced Recovery After Surgery Strategy.

Front Surg 2021 26;8:645935. Epub 2021 Mar 26.

Department of Hepatobiliary Surgery, Inner Mongolia Xing'an Meng People's Hospital, Ulanhot, China.

For the first time in China, the current study was designed to compare the clinical outcomes between Chinese patients receiving hepatectomy with or without the enhanced recovery after surgery (ERAS) strategy. The current study enrolled 250 patients who would receive hepatectomy. Patients were randomized into two groups: ERAS group ( = 125, ERAS strategy) and control ( = 125, conventional care). Read More

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Exploring Changes in Musical Behaviors of Caregivers and Children in Social Distancing During the COVID-19 Outbreak.

Front Psychol 2021 24;12:633499. Epub 2021 Mar 24.

Center for Mathematics, Computing and Cognition, Universidade Federal do ABC, Santo André, Brazil.

The coronavirus disease 2019 (COVID-19) pandemic has had profound effects on all aspects of society. Families were among those directly impacted by the first measures imposed by health authorities worldwide to contain the spread of the Sars-CoV-2 virus, where social distancing and mandatory quarantine were the main approaches implemented. Notably, little is yet known about how social distancing during COVID-19 has altered families' daily routines, particularly regarding music-related behaviors. Read More

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EC of sevoflurane for classic laryngeal mask airway insertion in children at different time points: A randomized blind trial.

J Anaesthesiol Clin Pharmacol 2020 Oct-Dec;36(4):489-493. Epub 2021 Jan 18.

Department of Ophthalmology, PGIMER, Chandigarh, India.

Background And Aims: Literature documents EC (End-tidal) of sevoflurane for CLMA (Classic Laryngeal Mask airway) insertion between 1.5 and 2% and most of these studies suggest maintaining the required end-tidal sevoflurane concentration for 10-25 minutes before LMA insertion. Waiting for this long interval for blood brain sevoflurane equilibration may not be feasible in children especially during failed ventilation. Read More

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January 2021

Challenges and Solutions for Physician Mothers: A Critical Review of the Literature.

Mayo Clin Proc 2021 Apr 8. Epub 2021 Apr 8.

Department of Internal Medicine, Mayo Clinic, Rochester, MN.

Physician mothers face unique challenges related to family planning, pregnancy, childcare, work-life integration, inequities, and biases that may have serious widespread implications. There is a paucity of available information on the extent and ramifications of such challenges and related solutions. The purpose of this critical review of the literature was to identify and summarize challenges and solutions pertaining to physician mothers. Read More

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Medical Financial Hardship in Survivors of Adolescent and Young Adult Cancer in the United States.

J Natl Cancer Inst 2021 Apr 11. Epub 2021 Apr 11.

Department of Paediatrics, University of Toronto, Toronto, ON, Canada.

Background: Cancer and its treatment can result in lifelong medical financial hardship, which we aimed to describe among adult survivors of adolescent and young adult (AYA) cancers in the United States.

Methods: We identified adult (aged ≥18 years) survivors of AYA cancers (diagnosed ages 15-39 years) and adults without a cancer history from the 2010-2018 National Health Interview Surveys. Proportions of respondents reporting measures in different hardship domains (material [eg, problems paying bills], psychological [eg, distress], and behavioral [eg, forgoing care due to cost]) were compared between groups using multivariable logistic regression models and hardship intensity (cooccurrence of hardship domains) using ordinal logistic regression. Read More

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Child witchcraft confessions as an idiom of distress in Sierra Leone; results of a rapid qualitative inquiry and recommendations for mental health interventions.

Child Adolesc Psychiatry Ment Health 2021 Apr 9;15(1):18. Epub 2021 Apr 9.

University of Amsterdam, Amsterdam, The Netherlands.

Background: Reports about child witchcraft are not uncommon in sub-Saharan Africa. In this study we approach child witchcraft as an idiom of distress. In an environment that may prohibit children from openly expressing distress, the shared imagery of witchcraft can provide a cultural idiom to communicate about psychosocial suffering. Read More

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Association Between Specific Childhood Adversities and Symptom Dimensions in People With Psychosis: Systematic Review and Meta-Analysis.

Schizophr Bull 2021 Apr 9. Epub 2021 Apr 9.

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Despite the accepted link between childhood abuse and positive psychotic symptoms, findings between other adversities, such as neglect, and the remaining dimensions in people with psychosis have been inconsistent, with evidence not yet reviewed quantitatively. The aim of this study was to systematically examine quantitatively the association between broadly defined childhood adversity (CA), abuse (sexual/physical/emotional), and neglect (physical/emotional) subtypes, with positive, negative, depressive, manic, and disorganized dimensions in those with psychosis. A search was conducted across EMBASE, MEDLINE, PsychINFO, and Cochrane Libraries using search terms related to psychosis population, CA, and psychopathological dimensions. Read More

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Bleeding Severity and Phenotype in 22q11.2 Deletion Syndrome - A Cross-sectional Investigation.

J Pediatr 2021 Apr 6. Epub 2021 Apr 6.

Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA; Department of Pediatrics, Harvard Medical School, Boston, MA. Electronic address:

Objectives: To prospectively quantify bleeding severity and elaborate hemorrhagic symptoms in children with 22q11.2 deletion syndrome (22q11DS) using two validated bleeding-assessment-tools (BATs), namely the pediatric bleeding questionnaire (PBQ) and the International Society on Thrombosis and Hemostasis BAT (ISTH-BAT). We additionally sought to compare subjects' bleeding scores to unaffected first-degree family members. Read More

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The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory.

Pharmacol Rep 2021 Apr 9. Epub 2021 Apr 9.

Department of Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, Kagoshima, 890-8544, Japan.

Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) plays an essential role in the modulation of astrocyte functions. Although lactate secretion from astrocytes contributes to many forms of neuronal plasticity in the central nervous system, including fear learning and memory, the role of PACAP in lactate secretion from astrocytes is unclear.

Methods: The amygdala and hippocampus of PACAP (+ / +) and PACAP (-/-) mice were acquired 1 h after memory acquisition and recall in the passive avoidance test. Read More

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Neonatal Screening for Congenital Metabolic and Endocrine Disorders.

Dtsch Arztebl Int 2021 Feb;118(7):101-108

Bavarian State Office for Health and Food Safety: Health Reporting, Epidemiology, Social Medicine, Child Health, Screening Center, Oberschleißheim; Institute for Experimental Pediatric Endocrinology, Charité-University Medical Center Berlin; Department of Child Nutrition, Federal Research Institute of Nutrition and Food, Max Rubner Institute, Karlsruhe; Department of General Pediatrics, Neonatology, and Pediatric Cardiology, University Children's Hospital, Heinrich Heine University Düsseldorf; The Hospital for Sick Children and University of Toronto, Canada; Neonatal Metabolic Screening, Hessian Center for Preventive Care in Children, Screening Center; Hesse, University Hospital Frankfurt/Main.

Background: The purpose of neonatal screening is the early detection of congenital metabolic and endocrine disorders that, if untreated, could lead to fatal crises or other long-term adverse sequelae. In Germany, neonatal screening is legally regulated. Quality-assurance reports ("DGNS reports") are created and published annually by the German Society for Neonatal Screening (Deutsche Gesellschaft für Neugeborenen-Screening). Read More

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February 2021

Are Older Persons in China Living More Years in an Independent Living Arrangement? Estimates Using Multistate Life Tables.

Demography 2021 Apr;58(2):739-762

Academia Sinica, Taipei, Taiwan.

Adopting a multistate life table approach, this study estimates number of years the very old in China expect to live in an independent living arrangement (alone or with spouse only)-an estimate we term "independent living life expectancy" (ILLE)-as opposed to in coresidence with adult children or others. We also estimate how ILLE and proportion of total life expectancy (TLE) residing independently has changed over time. The backdrop for this study is a society experiencing both increasing longevity and social changes that influence the tendency to live in an independent living arrangement. Read More

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Exploring Strategies for Investigating the Mechanisms Linking Climate and Individual-Level Child Health Outcomes: An Analysis of Birth Weight in Mali.

Demography 2021 Apr;58(2):499-526

Climate Hazards Center, UC Santa Barbara, Santa Barbara, CA, USA.

The goal of this article is to consider data solutions to investigate the differential pathways that connect climate/weather variability to child health outcomes. We apply several measures capturing different aspects of climate/weather variability to different time periods of in utero exposure. The measures are designed to capture the complexities of climate-related risks and isolate their impacts based on the timing and duration of exposure. Read More

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Asthma in South African adolescents: a time trend and risk factor analysis over two decades.

ERJ Open Res 2021 Apr 6;7(2). Epub 2021 Apr 6.

University of Cape Town, Dept of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, and the SA-MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.

Background: South Africa has undergone major economic and health system changes, impacting the epidemiology of childhood asthma. This study aimed to investigate prevalence time trends of asthma in South African adolescents over two decades and to identify associated risk factors.

Methods: A cross-sectional survey was conducted in 2017, in a randomised sample of 13-14-year-old Cape Town adolescents, using the standardised Global Asthma Network written, video and environmental questionnaires. Read More

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Variants in PRKAR1B cause a neurodevelopmental disorder with autism spectrum disorder, apraxia, and insensitivity to pain.

Genet Med 2021 Apr 8. Epub 2021 Apr 8.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

Purpose: We characterize the clinical and molecular phenotypes of six unrelated individuals with intellectual disability and autism spectrum disorder who carry heterozygous missense variants of the PRKAR1B gene, which encodes the R1β subunit of the cyclic AMP-dependent protein kinase A (PKA).

Methods: Variants of PRKAR1B were identified by single- or trio-exome analysis. We contacted the families and physicians of the six individuals to collect phenotypic information, performed in vitro analyses of the identified PRKAR1B-variants, and investigated PRKAR1B expression during embryonic development. Read More

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A Sector Wheel Approach to Understanding the Needs and Barriers to Services among Homeless-Experienced Veteran Families.

J Am Board Fam Med 2021 Mar-Apr;34(2):309-319

From the VA Health Service Research & Development (HSR&D) Center for the Study of Healthcare Innovation, Implementation & Policy (CSHIIP), VA Greater Los Angeles Healthcare System, Los Angeles, CA (RI-M, LG); UCLA Division of Population Behavioral Health, Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA (RI-M, SK); Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA (RI-M, SF, SK); Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California (GWR); Office of Healthcare Transformation and Innovation, VA Greater Los Angeles Healthcare System, Los Angeles, CA (LA, LG); Department of Medicine, David Geffen School of Medicine at UCLA (LA, DLW); UCLA Center for Health Services and Society, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA (SK); Department of Family Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA (LG); and Department of Health Policy and Management, UCLA Fielding School of Public Health, Los Angeles, CA (LG).

Background: Veteran family homelessness is a significant issue, yet little is known about the needs and barriers to services of veteran families experiencing homelessness. This qualitative study examined the experiences, needs, and barriers to services among homeless-experienced veteran families to inform providers for this important population.

Methods: Twenty-five semi-structured interviews were conducted from February through September 2016 with 18 veteran parents with a recent history of homelessness (9 mothers, 9 fathers), and 7 homeless service providers throughout Los Angeles County. Read More

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From income inequality to social inequity: impact on health levels in an international efficiency comparison panel.

BMC Public Health 2021 Apr 8;21(1):688. Epub 2021 Apr 8.

Department of Policies, Management and Health, Faculdade de Saúde Pública - FSP (School of Public Health), Universidade de São Paulo - USP (Sao Paulo University), Av. Dr. Arnaldo 715, Cerqueira César, São Paulo, SP, 01246-904, Brazil.

Background: Health equity, although addressed in several publications dealing with health efficiency analysis, is not easily translated into the operationalization of variables, mainly due to technical difficulties. Some studies provide evidence that it does not influence health outcomes; others demonstrate that its effect is an indirect one, with the hegemony of material living conditions over its social connotation. The aim of this article is to evaluate the role of health equity in determining health outcomes, in an international comparative analysis of the effectiveness and efficiency of health systems. Read More

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Public health practitioner perspectives on dealing with measles outbreaks if high anti-vaccination sentiment is present.

BMC Public Health 2021 04 9;21(1):578. Epub 2021 Apr 9.

Australian Centre for Health Engagement, Evidence & Values (ACHEEV), School of Health and Society, Faculty of the Arts, Social Sciences & Humanities, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.

Background: Communities with low vaccination rates are at greater risk during outbreaks of vaccine preventable diseases. Most Australian parents support vaccines, but some refuse and are often judged harshly by their community, especially during an outbreak. We sought the perspectives of Australian public health experts on the key issues faced when managing a measles outbreak in an area with high anti-vaccination sentiment. Read More

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Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020.

J Headache Pain 2021 Apr 8;22(1):22. Epub 2021 Apr 8.

Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Valdemar Hansen Vej 5, 2600, Glostrup, Denmark.

Headache and facial pain are among the most common, disabling and costly diseases in Europe, which demands for high quality health care on all levels within the health system. The role of the Danish Headache Society is to educate and advocate for the needs of patients with headache and facial pain. Therefore, the Danish Headache Society has launched a third version of the guideline for the diagnosis, organization and treatment of the most common types of headaches and facial pain in Denmark. Read More

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Korean Society of Thyroid Radiology (KSThR) guidelines for the management of pediatric thyroid nodules: Suitability and risk factors.

Thyroid 2021 Apr 9. Epub 2021 Apr 9.

Seoul National University College of Medicine, 37990, Radiology, Seoul, Korea (the Republic of);

Background: The guideline for managing pediatric thyroid nodules has not been established. We investigated the appropriateness of the Korean Society of Thyroid Radiology (KSThR) guidelines and the need to consider risk factors for managing pediatric thyroid nodules.

Methods: From August 2007 to February 2020, a database of thyroid nodules in patients under 19 years of age who underwent fine needle aspiration (FNA) was analyzed. Read More

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[Forcasting the prevalence of myopia among students aged 6-18 years in China from 2021 to 2030].

Zhonghua Yan Ke Za Zhi 2021 Apr;57(4):261-267

Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Division of Ophthalmology Shanghai General Hospital, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai 200040, China.

To predict the prevalence of myopia among Chinese students aged 6-18 years under different intervention scenarios from 2021 to 2030. The multi-state Markov model was developed based on the transition process of study stages and myopia statuses. The development of myopia was simplified into two statuses: non-myopia and myopia. Read More

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Childhood exposure to ambient air pollution and predicting individual risk of depression onset in UK adolescents.

J Psychiatr Res 2021 Mar 25;138:60-67. Epub 2021 Mar 25.

King's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK; ESRC Centre for Society and Mental Health, King's College London, London, UK. Electronic address:

Knowledge about early risk factors for major depressive disorder (MDD) is critical to identify those who are at high risk. A multivariable model to predict adolescents' individual risk of future MDD has recently been developed however its performance in a UK sample was far from perfect. Given the potential role of air pollution in the aetiology of depression, we investigate whether including childhood exposure to air pollution as an additional predictor in the risk prediction model improves the identification of UK adolescents who are at greatest risk for developing MDD. Read More

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Impact of obesity on risk of cancer.

Cent Eur J Public Health 2021 Mar;29(1):38-44

Department of Epidemiology, School of Health Sciences, Medical University of Silesia in Katowice, Katowice, Poland.

Epidemiological data consistently show sustained upward trend in the incidence of cancer. The International Agency for Research on Cancer (IARC) estimated that in 2018 more than 18 million people were diagnosed with cancer, and in about 9.6 million cases cancer could be the cause of death. Read More

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A Data-Based Approach to Evaluate Representation by Gender and Affiliation in Key Presentation Formats at the SER Annual Meeting.

Am J Epidemiol 2021 Apr 8. Epub 2021 Apr 8.

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.

The Society for Epidemiologic Research's (SER) annual meeting is a major forum for sharing new research and promoting participants' career development. As such, evaluating representation in key presentation formats is critical. For the 3,257 presentations identified at the 2015-2017 SER annual meetings, we evaluated presenter characteristics, including gender, affiliation, subject area and h-index, and representation in three highlighted presentation formats: platform talks (n=382), invited symposium talks (n=273) and serving as a Concurrent Contributed Session or symposium chair (n=188). Read More

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[The concept of paedophilia. Part 2: Etiologies, forensic aspects and therapeutic options].

Rev Med Liege 2021 Apr;76(4):268-272

Département de Psychiatrie et Addictologie, CHU Cochin (APHP), Université de Paris, INSERM U1266, IPNP, Paris, France.

Paedophilia is a paraphilia characterised by behaviour, drives or sexual fantasies that are intense and recurring and that generally involve children. This sexual deviation is often linked to personal distress, to a significant alteration of personal, family, professional and social life, in a general sense. In our modern Western societies, paedophilia and the perversions associated with it are punishable by law. Read More

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How ancestral subsistence strategies solve salmon starvation and the "protein problem" of Pacific Rim resources.

Am J Phys Anthropol 2021 Apr 8. Epub 2021 Apr 8.

Department of Anthropology, University of California, Davis, California, USA.

This article provides a theoretical treatment of hunter-gatherer diet and physiology. Through a synthesis of nutritional studies, informed by ethno-archaeological data, we examine the risk of protein-rich diets for human survival, and how societies circumvent "salmon starvation" in the northeastern Pacific Rim. Fundamental nutritional constraints associated with salmon storage and consumption counter long-standing assumptions about the engine of cultural evolution in the region. Read More

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