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Applying the Exploration, Preparation, Implementation, Sustainment (EPIS) Framework to Safe Surgery 2020 Implementation in Tanzania's Lake Zone.

J Am Coll Surg 2021 Apr 14. Epub 2021 Apr 14.

Department of Health, Social Welfare and Nutrition Service, President's Office Regional Administration and Local Government, Dodoma, Tanzania; Center for Reforms, Innovation, Health Policies and Implementation Research (CeRIHI), Dodoma, Tanzania.

Background: Access to safe, high-quality surgical care in sub-Saharan Africa is a critical gap. Interventions to improve surgical quality have been developed, but research on their implementation is still at a nascent stage. We retrospectively applied the Exploration, Preparation, Implementation, Sustainment Framework to characterize the implementation of Safe Surgery 2020, a multicomponent intervention to improve surgical quality. Read More

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The ongoing indirect effect of the COVID-19 pandemic on a pediatric emergency department.

PLoS One 2021 6;16(5):e0251003. Epub 2021 May 6.

Shaare Zedek Medical Center and the Faculty of Medicine at the Hebrew University in Jerusalem, Pediatric Emergency Department, Jerusalem, Israel.

Introduction: The SARS-CoV-2 coronavirus pandemic may cause significant morbidity and mortality in adults, yet severe cases are rare among children. The indirect impact of the pandemic on health care delivery in general and pediatric emergency department (PED) visits in particular has been widely reported.

Aims: To assess the impact of the pandemic and the social restrictions imposed in its wake on PED visits and hospitalization rates in our Israeli medical center. Read More

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Are work well-being variables distinct? A bifactor model of fulfilling work.

J Couns Psychol 2021 May 6. Epub 2021 May 6.

Department of Psychology, University of Minnesota Duluth.

The strengths-based inclusive theory of work and psychology of working theory propose that fulfilling work is a key outcome of the vocational intervention. Scholars have further argued that fulfilling work is the holistic experience of well-being in the workplace and can be assessed with meaningful work, work engagement, workplace positive emotions, and job satisfaction. This theoretical perspective suggests a bifactor model would best explain the relations among these variables, but this claim remains untested. Read More

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On the investigation of COVID-19 lockdown influence on air pollution concentration: regional investigation over eighteen provinces in Iraq.

Environ Sci Pollut Res Int 2021 May 6. Epub 2021 May 6.

New era and development in civil engineering research group, Scientific Research Center, Al-Ayen University, Thi-Qar, 64001, Iraq.

At the end of 2019, a novel coronavirus COVID-19 emerged in Wuhan, China, and later spread throughout the world, including Iraq. To control the rapid dispersion of the virus, Iraq, like other countries, has imposed national lockdown measures, such as social distancing, restriction of automobile traffic, and industrial enterprises. This has led to reduced human activities and air pollutant emissions, which caused improvement in air quality. Read More

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Characterizing Social Functioning in School-Age Children with Sensory Processing Abnormalities.

J Autism Dev Disord 2021 May 6. Epub 2021 May 6.

Center On Human Development and Disability, University of Washington, Seattle, WA, USA.

Children with sensory abnormalities (SAs) have a variety of social problems resulting in poorer social functioning than children with typical development (TD). We describe the relationship between SAs and social functioning in school-age children with SAs, children with TD and a clinical comparison sample of children with autism spectrum disorder (ASD). Children with SAs demonstrated impaired social functioning on standardized measures. Read More

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Back to basics for curricular development: A proposed framework for thinking about how interprofessional learning occurs.

J Interprof Care 2021 May 6:1-10. Epub 2021 May 6.

Frances Payne Bolton School of Nursing, Health Education Campus, Cleveland, OH, USA.

The persistent difficulty of defining the mechanisms of interprofessional learning that can lead to collaborative behavior poses a challenge to evidence-based curricular design. To begin the process of building a framework for curricular development we used an inductive approach to better understand the lived experience of students engaged in an interprofessional activity. Utilizing methods from grounded theory, we analyzed reflective essays from an interprofessional classroom-based workshop for early learners at Case Western Reserve University. Read More

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Understanding interprofessional team delivery of patient-centered care: a qualitative secondary analysis.

J Interprof Care 2021 May 6:1-8. Epub 2021 May 6.

College of Nursing, University of Manitoba, Winnipeg, Canada.

Primary Care providers are expected to deliver patient-centered care (PCC) within teams; however, PCC tends to be studied within the provider-patient dyad, often to the exclusion of interprofessional team relationships. The purpose of this study was to explore how PCC is understood in the context of inter-provider relationships within Collaborative Mental Health Care teams. Previously collected data formed the basis of a qualitative secondary analysis using constructivist grounded theory. Read More

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Comparing the Effectiveness of Sexual Counseling Based on PLISSITand BETTER Models on Sexual Selfdisclosure in Women with Sexual Problems after Childbirth: A Randomized Trial.

Iran J Nurs Midwifery Res 2021 Jan-Feb;26(1):68-74. Epub 2021 Jan 18.

Social Determinants of Health Research Center, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Sexual self-disclosure is one of the factors that affect sexual satisfaction. The aim of this study was to assess the efficacy of individual therapy using the Bring up, Explain, Tell, Timing, Educate, and Record (BETTER model) in comparison to individual therapy using the Permission, Limited Information, Specific Suggestions, and Intensive Therapy (PLISSIT model) in terms of increasing sexual self-disclosure in women with sexual problems after childbirth.

Materials And Methods: This randomized trial was conducted in 2017 in Mashhad, Iran. Read More

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January 2021

"Do I Have a Memory Problem? I Can't Recall": An Evaluation of Measurement Invariance in Subjective Reporting of Memory Symptoms among Persons with and without Objective HIV-Associated Memory Impairment.

J Int Neuropsychol Soc 2021 May 6:1-11. Epub 2021 May 6.

Department of Psychology, University of Houston, Houston, USA.

Objective: Memory symptoms and objective impairment are common in HIV disease and are associated with disability. A paradoxical issue is that objective episodic memory failures can interfere with accurate recall of memory symptoms. The present study assessed whether responses on a self-report scale of memory symptoms demonstrate measurement invariance in persons with and without objective HIV-associated memory impairment. Read More

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Predicting prognosis for adults with depression using individual symptom data: a comparison of modelling approaches.

Psychol Med 2021 May 6:1-11. Epub 2021 May 6.

Research Department of Clinical, Educational & Health Psychology, Centre for Outcomes Research and Effectiveness (CORE), University College London, 1-19 Torrington Place, London, UK.

Background: This study aimed to develop, validate and compare the performance of models predicting post-treatment outcomes for depressed adults based on pre-treatment data.

Methods: Individual patient data from all six eligible randomised controlled trials were used to develop (k = 3, n = 1722) and test (k = 3, n = 918) nine models. Predictors included depressive and anxiety symptoms, social support, life events and alcohol use. Read More

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Profile Analysis of Sexual Assault Experiences among Adult Women and Their Implications for Mental Health.

Psychiatry Investig 2021 Apr 25;18(4):312-323. Epub 2021 Apr 25.

Division of Child and Adolescent Psychiatry, Department of Psychiatry & Behavioral Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.

Objective: Extant studies indicate that just one characteristic of sexual assault cannot properly represent the whole experience of sexual assault and, especially, the severity of sexual assault. This study aimed to understand the totality of sexual assault experiences and elucidate subtypes of sexual assault victims based on the detailed characteristics of their sexual assault experiences and those relationships with mental health.

Methods: A total of 255 adult sexual violence victims who used intervention services and a comparison group were included. Read More

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Comparison of islet cell function, insulin sensitivity, and incretin axis between Asian-Indians with either impaired fasting glucose or impaired glucose tolerance, and normal healthy controls.

Diabetes Res Clin Pract 2021 May 2:108846. Epub 2021 May 2.

Department of Endocrinology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Puducherry, India.

Aims: The objective of this study was to compare the islet cell function, insulin sensitivity, and incretin axis between Asian-Indians subjects with either impaired fasting glucose (IFG), or impaired glucose tolerance (IGT), and normal glucose tolerance (NGT).

Materials And Methods: Prediabetes subjects underwent a mixed meal tolerance test after overnight fasting. Samples for glucose, insulin, glucagon, and glucagon-like peptide-1 (GLP-1) were collected at 0, 30, 60, and 120 minutes. Read More

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Conducting a multi-country online alcohol survey in the time of the COVID-19 pandemic: Opportunities and challenges.

Int J Methods Psychiatr Res 2021 May 5. Epub 2021 May 5.

Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.

Objectives: This contribution provides insights into the methodology of a pan-European population-based online survey, performed without external funding during the COVID-19 pandemic. We present the impact of different dissemination strategies to collect data from a non-probabilistic convenience sample and outline post-stratification weighting schemes, to provide guidance for future multi-country survey studies.

Methods: Description and comparison of dissemination strategies for five exemplary countries (Czechia, Germany, Lithuania, Norway, Spain) participating in the Alcohol Use and COVID-19 Survey. Read More

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Treatment outcomes of a lesbian, gay, bisexual, transgender and queer alcohol and other drug counselling service in Australia: A retrospective analysis of client records.

Drug Alcohol Rev 2021 May 5. Epub 2021 May 5.

Centre for Social Research in Health, UNSW Sydney, Sydney, Australia.

Introduction: Substance use disorders are more prevalent among lesbian, gay, bisexual, transgender and queer (LGBTQ) people than among their heterosexual and cisgender peers. There has been limited alcohol and other drug (AOD) treatment research with LGBTQ people outside of North America. This study aimed to examine the treatment outcomes of clients attending a LGBTQ-specific AOD counselling service in Australia (ACON's Substance Support Service) and compare their client profile and treatment outcomes with LGBTQ and non-LGBTQ clients of similar mainstream services. Read More

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'We have become prisoners of our own age': from a continuing care retirement community to a total institution in the midst of the COVID-19 outbreak.

Age Ageing 2021 05;50(3):664-667

Faculty of Social and Community Sciences, Ruppin Academic Center, Emek Hefer, 4025000, Israel.

Background And Objectives: during the coronavirus disease 2019 pandemic in Israel, people residing in continuing care retirement communities (CCRC) found themselves under strict instructions to self-isolate, imposed by the CCRC managements before, during and after the nationwide lockdown. The present study explored the personal experiences of CCRC residents during the lockdown.

Research Design And Methods: in-depth interviews were conducted with 24 CCRC residents from 13 different CCRCs. Read More

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How well did experts and laypeople forecast the size of the COVID-19 pandemic?

PLoS One 2021 5;16(5):e0250935. Epub 2021 May 5.

Department of Pure Mathematics and Mathematical Statistics, Winton Centre for Risk and Evidence Communication, University of Cambridge, Cambridge, United Kingdom.

Throughout the COVID-19 pandemic, social and traditional media have disseminated predictions from experts and nonexperts about its expected magnitude. How accurate were the predictions of 'experts'-individuals holding occupations or roles in subject-relevant fields, such as epidemiologists and statisticians-compared with those of the public? We conducted a survey in April 2020 of 140 UK experts and 2,086 UK laypersons; all were asked to make four quantitative predictions about the impact of COVID-19 by 31 Dec 2020. In addition to soliciting point estimates, we asked participants for lower and higher bounds of a range that they felt had a 75% chance of containing the true answer. Read More

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Factors affecting primary care practitioners' alcohol-related discussions with older adults: Qualitative study.

Br J Gen Pract 2021 May 4. Epub 2021 May 4.

Newcastle University Population Health Sciences Institute, Newcastle upon Tyne, United Kingdom.

Background: Risk of harm from drinking is heightened in later life, due to age-related sensitivities to alcohol. Primary care services have a key role in supporting older people to make healthier decisions about alcohol.

Aim: To examine primary care practitioners' perceptions of factors that promote and challenge their work to support older people in alcohol risk-reduction. Read More

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Sexually Dimorphic Perineuronal Nets in the Rodent and Primate Reproductive Circuit.

J Comp Neurol 2021 May 5. Epub 2021 May 5.

Epigenetics & Neurobiology Unit, EMBL, Rome, European Molecular Biology Laboratory, Monterotondo, Italy.

Perineuronal nets are extracellular glycoprotein structures that have been found on some neurons in the central nervous system and that have been shown to regulate their structural plasticity. Until now work on perineuronal nets has been focused on their role in cortical structures where they are selectively expressed on parvalbumin-positive neurons and are reported to restrict the experience-dependent plasticity of inhibitory afferents. Here we examined the expression of perineuronal nets subcortically, showing that they are expressed in several discrete structures, including nuclei that comprise the brain network controlling reproductive behaviors (e. Read More

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ConVid - Behavior Survey by the Internet during the COVID-19 pandemic in Brazil: conception and application methodology.

Cad Saude Publica 2021 30;37(3):e00268320. Epub 2021 Apr 30.

Instituto de Comunicação e Informação Científica e Tecnológica em Saúde, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.

The ConVid - Behavior Survey was conducted in Brazil from April 24 to May 24, 2020, aiming to investigate changes in lifestyles and health conditions during the COVID-19 pandemic. In this article, we present the conception and methodology of the research. We used a cross-sectional study using an Internet questionnaire, with questions validated in previous health surveys. Read More

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Persistence with medical treatment for Wilson disease in China based on a single center's survey research.

Brain Behav 2021 May 5:e02168. Epub 2021 May 5.

Department of Neurology, The first affiliated hospital, School of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, China.

Background: Wilson's disease (WD) is one of the few hereditary diseases that can be successfully treated with medicines. We conduct this survey research to assess treatment persistence among patients with WD and try to identify what factors affect the treatment persistence.

Methods: We employed WeChat which is the most popular social software in China to carry out this anonymous questionnaire research. Read More

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Increased prevalence of the CVD-associated ANRIL allele in the Roma/Gypsy population in comparison with the majority Czech population.

Genet Mol Biol 2021 30;44(2):e20200405. Epub 2021 Apr 30.

University of South Bohemia, Faculty of Health and Social Sciences, České Budějovice, Czech Republic.

Cardiovascular disease (CVD) is a major cause of death around the world, with highest prevalence reported in minority Roma/Gypsy populations living in developed countries. Whether these differences are caused by unhealthy lifestyles or genetic factors remain unknown. The aim of our study was to examine the genotype frequencies of the rs10757274 polymorphism in the 9p. Read More

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Theoretical Mediators of Diabetes Risk and Quality of Life Following a Diabetes Prevention Program for Latino Youth With Obesity.

Am J Health Promot 2021 May 5:8901171211012951. Epub 2021 May 5.

Center for Health Promotion and Disease Prevention, Arizona State University, Phoenix, AZ, USA.

Purpose: This study tested self-efficacy and social support for activity and dietary changes as mediators of changes in type 2 diabetes related outcomes following a lifestyle intervention among Latino youth.

Setting And Intervention: Latino adolescents (14-16 years) with obesity (BMI% = 98.1 ± 1. Read More

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Impact of natalizumab on quality of life in a real-world cohort of patients with multiple sclerosis: Results from MS PATHS.

Mult Scler J Exp Transl Clin 2021 Apr-Jun;7(2):20552173211004634. Epub 2021 Apr 15.

Biogen, Cambridge, MA, USA, at the time of these analyses.

Background: Optimizing multiple sclerosis treatment warrants understanding of changes in physical, mental, and social health.

Objective: To assess the impact of natalizumab on Quality of Life in Neurological Disorders (Neuro-QoL) scores.

Methods: Annualized change in T-scores and likelihood of ≥5-point improvement over baseline were calculated for each Neuro-QoL domain after natalizumab initiation. Read More

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Cervical ripening at home or in-hospital-prospective cohort study and process evaluation (CHOICE) study: a protocol.

BMJ Open 2021 May 4;11(5):e050452. Epub 2021 May 4.

Edinburgh Clinical Trials Unit (ECTU) Usher Institute, University of Edinburgh, Edinburgh, UK.

Introduction: The aim of the cervical ripening at home or in-hospital-prospective cohort study and process evaluation (CHOICE) study is to compare home versus in-hospital cervical ripening to determine whether home cervical ripening is safe (for the primary outcome of neonatal unit (NNU) admission), acceptable to women and cost-effective from the perspective of both women and the National Health Service (NHS).

Methods And Analysis: We will perform a prospective multicentre observational cohort study with an internal pilot phase. We will obtain data from electronic health records from at least 14 maternity units offering only in-hospital cervical ripening and 12 offering dinoprostone home cervical ripening. Read More

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Evaluating pictorial support in person-centred care for children (PicPecc): a protocol for a crossover design study.

BMJ Open 2021 May 4;11(5):e042726. Epub 2021 May 4.

University of Gothenburg Centre for Person-Centred Care, and Institute of Health and Care Sciences, University of Gothenburg, Gothenburg, Sweden.

Introduction: This study protocol outlines the evaluation of the pictorial support in person-centred care for children (PicPecc). PicPecc is a digital tool used by children aged 5-17 years to self-report symptoms of acute lymphoblastic leukaemia, who undergo high-dose methotrexate treatments. The design of the digital platform follows the principles of universal design using pictorial support to provide accessibility for all children regardless of communication or language challenges and thus facilitating international comparison. Read More

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Exploring the heterogeneity of factors that may influence implementation of PrEP in family planning clinics: a latent profile analysis.

Implement Sci Commun 2021 May 4;2(1):48. Epub 2021 May 4.

Department of Behavioral, Social, and Health Education Science, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Background: Title X-funded family planning clinics have been identified as optimal sites for delivery of pre-exposure prophylaxis (PrEP) for HIV prevention. However, PrEP has not been widely integrated into family planning services, especially in the Southern US, and data suggest there may be significant implementation challenges in this setting. Because Title X clinics vary greatly in provider-, organizational-, and systems-level characteristics, there is likely variation in capacity to implement PrEP across clinics. Read More

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Categorizing IQOS-Related Twitter Discussions.

Int J Environ Res Public Health 2021 Apr 30;18(9). Epub 2021 Apr 30.

Department of Preventative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

(1) Background: The heated tobacco product IQOS, by Philip Morris International, is now available in over 55 countries, including the United States. Social media sites such as Twitter are often used to promote or discuss tobacco products, though prior research has not examined how IQOS is presented on Twitter. (2) Methods: This study collected and categorized Twitter conversations involving IQOS. Read More

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