4,611 results match your criteria snellen

Improving health-related quality of life in glaucoma during 11 years and its association with vision loss and treatment of the disease.

Acta Ophthalmol 2021 May 6. Epub 2021 May 6.

Department of Ophthalmology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Purpose: To evaluate the impact of glaucoma on health-related quality of life (HRQoL) and mental health in the ageing population of Finland.

Methods: Altogether 7380 and 5774 Finnish individuals aged 30 years and older with known eye disease status were studied in 2000 and 2011, respectively, in two population-based surveys, including an 11-year follow-up of 4683 participants. Data on HRQoL (EQ-5D-3L, 15D), depression (BDI), psychological distress (GHQ-12) and eye disease diagnoses were obtained from self-reported assessments. Read More

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Frequency and phenotypic characteristics of RPE65 mutations in the Chinese population.

Orphanet J Rare Dis 2021 Apr 13;16(1):174. Epub 2021 Apr 13.

Eye Institute, Eye and ENT Hospital, College of Medicine, Fudan University, Shanghai, 200032, China.

Background: The retinoid isomerohydrolase RPE65 has received considerable attention worldwide since a successful clinical gene therapy was approved in 2017 as the first treatment for vision loss associated with RPE65-mediated inherited retinal disease. Identifying patients with RPE65 mutations is a prerequisite to assessing the patients' eligibility to receive RPE65-targeted gene therapies, and it is necessary to identify individuals who are most likely to benefit from gene therapies. This study aimed to investigate the RPE65 mutations frequency in the Chinese population and to determine the genetic and clinical characteristics of these patients. Read More

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Chromatic and flicker threshold changes in age-related macular degeneration following anti-VEGF treatment.

Clin Exp Optom 2021 May 3:1-7. Epub 2021 May 3.

Brien Holden Institute of Optometry and Vision Science, L. V. Prasad Eye Institute, Hyderabad, India.

: Red-green chromatic sensitivity and photopic (cone-mediated) flicker sensitivity showed marked improvement after anti-VEGF treatment. The use of flicker and chromatic sensitivities as potential functional tests to monitor treatment outcomes in age-related macular degeneration highlights the clinical importance.: High-contrast visual acuity (VA) is not a sensitive clinical marker in the management of age-related macular degeneration (AMD). Read More

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Long term results of accelerated 9 mW corneal crosslinking for early progressive keratoconus: the Siena Eye-Cross Study 2.

Eye Vis (Lond) 2021 May 1;8(1):16. Epub 2021 May 1.

Departmental Ophthalmology Unit, USL Toscana Sud-Est, Campostaggia, Siena, Italy.

Purpose: To assess clinical results of the 9 mW/5.4 J/cm accelerated crosslinking (ACXL) in the treatment of progressive keratoconus (KC) over a span of 5 years.

Methods: The prospective open non-randomized interventional study (Siena Eye-Cross Study 2) included 156 eyes of 112 patients with early progressive KC undergoing the Epi-Off 9 mW/5. Read More

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Vision loss, vision difficulty and psychological distress in South Africa: results from SANHANES-1.

BMC Psychol 2021 Apr 29;9(1):66. Epub 2021 Apr 29.

Health & Wellbeing, Human and Social Capabilities Division, Human Sciences Research Council, Cape Town, South Africa.

Background: Psychological distress in vision impairments and blindness is a complex issue and a major public health concern. Sudden adjustments in routine lifestyle and career aspirations in such persons culminate in and/or aggravate their level of stress. Yet, psychological distress in persons with visual difficulties and vision loss in South Africa is poorly understood. Read More

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Short-term outcomes of a modified technique for small-incision scleral-fixated intraocular lens implantation using Gore-Tex sutures.

Graefes Arch Clin Exp Ophthalmol 2021 Apr 29. Epub 2021 Apr 29.

Department of Ophthalmology, National Taiwan University Hospital, No 7, Chung-Shan S. Rd., Taipei, 100, Taiwan.

Purpose: To report the short-term outcomes of a modified small-incision technique for implantation of scleral-fixated intraocular lenses (IOLs) using Gore-Tex sutures.

Methods: A retrospective, interventional, consecutive case series was conducted. From June 2019 to February 2020, 10 patients underwent small-incision scleral-fixated IOL implantation using Gore-Tex sutures at a tertiary referral center. Read More

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Iris cerclage pupilloplasty and IOL implantation for traumatic mydriasis and aphakia after the blunt trauma of the eye.

Indian J Ophthalmol 2021 May;69(5):1314-1317

Eye Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia; Clinic for Eye Diseases, Clinical Centre of Serbia, Belgrade, Serbia.

Four patients with traumatic mydriasis and aphakia following blunt injury of the eye globe were evaluated. Patients with severe glare and photophobia due to wide pupil diameter from 6.0 to 9. Read More

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Effectiveness and Safety of the Clareon Monofocal Intraocular Lens: Outcomes from a 12-Month Single-Arm Clinical Study in a Large Sample.

Clin Ophthalmol 2021 20;15:1647-1657. Epub 2021 Apr 20.

Carolina Eye Associates, PA, Southern Pines, NC, USA.

Purpose: This study assessed effectiveness and safety of the novel Clareon intraocular lens (IOL; model SY60CL; Alcon Vision LLC).

Patients And Methods: This was a prospective, single-arm, unmasked clinical trial at 16 investigative clinical sites in the United States. Included were adults ≥22 years who required cataract extraction by phacoemulsification. Read More

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The impact of central foveal thickness and integrity of the outer retinal layers in the visual outcome of uveitic macular edema.

Int J Retina Vitreous 2021 Apr 27;7(1):36. Epub 2021 Apr 27.

Tecnologico de Monterrey, School of Medicine and Health Sciences, Institute of Ophthalmology and Visual Sciences, Ocular Immunology & Uveitis Service, Monterrey, Mexico.

Background: To analyze the relationship between the central foveal thickness (CFT) and the integrity of the ellipsoid portion of inner segments (EPIS) and interdigitating zone (IZ) retinal layers in the visual outcome of uveitic macular edema (UME).

Methods: Prospective, observational, and cross-sectional study of eyes with UME. Spectral-domain optical coherence tomography (SD-OCT) macular morphological pattern, CFT, and integrity of the outer retinal layers were analyzed. Read More

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Long-Term Outcomes of Macular Hole Repair with Triamcinolone Acetonide Visualization.

Clin Ophthalmol 2021 16;15:1607-1619. Epub 2021 Apr 16.

Retina Macula Institute and Research Center, Torrance, CA, USA.

Purpose: To evaluate the long-term anatomic and visual outcomes of macular hole (MH) repair utilizing triamcinolone acetonide (TA) visualization of the internal limiting membrane (ILM) treated at a tertiary care retina practice.

Methods: Retrospective chart review of eyes undergoing MH repair with ILM peel utilizing TA visualization followed by gas tamponade and facedown positioning between 2014 and 2020. Pre- and post-operative visual acuity (VA), IOP, and anatomic closure based on optical coherence tomography were documented. Read More

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Choroidal neovascularisation in a predicted female choroideraemia carrier treated with intravitreal anti-vascular endothelial growth factor.

Eur J Ophthalmol 2021 Apr;31(1_suppl):4-10

Princess Alexandra Eye Pavilion, Edinburgh, UK.

Purpose: To report a case of choroidal neovascularisation and leakage in a myopic female predicted to be a choroideraemia carrier treated with intravitreal anti-vascular endothelial growth factor (anti-VEGF).

Methods: Case report.

Results: A female magazine editor presented with sudden decrease in vision in her right eye, with Snellen visual acuities (VAs) of 1/60 and 3/60 in the right and left eyes respectively. Read More

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Clinical characteristics of progressive nonarteritic anterior ischemic optic neuropathy.

Int J Ophthalmol 2021 18;14(4):517-522. Epub 2021 Apr 18.

Neuro Ophthalmology Unit, Ophthalmology Department, Rabin Medical Center, Petah Tikva 4941492, Israel.

Aim: To study whether patients with progressive nonarteritic anterior ischemic optic neuropathy (NAION) present earlier than patients with stable NAION and to describe their clinical characteristics and visual outcome.

Methods: This was a retrospective chart review. All patients with NAION seen during the acute stage from January 2012 to December 2018 were reviewed. Read More

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Clinical course, treatment and visual outcome of an outbreak of Burkholderia contaminans endophthalmitis following cataract surgery.

J Ophthalmic Inflamm Infect 2021 Apr 19;11(1):12. Epub 2021 Apr 19.

Department of Ophthalmology, University Hospital of North Norway, Tromsø, Norway.

Background: Postoperative endophthalmitis is a rare but dreaded complication of intraocular surgery and often results in severe visual impairment or blindness. The present study describes the clinical course, treatment and visual outcome of an outbreak of Burkholderia contaminans endophthalmitis following cataract surgery.

Methods: Among 290 patients who underwent uneventful phacoemulsification cataract surgery at one outpatient clinic between January 4th and 28th 2019, 6 cases developed Burkholderia contaminans endophthalmitis. Read More

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Assessment of Refractive Outcomes of Femtosecond-assisted Laser in Situ Keratomileusis (LASIK) for Hyperopia.

J Coll Physicians Surg Pak 2021 Apr;30(4):434-439

Department of Refractive Surgery, Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.

Objective: To determine the effect of refractive treatment in terms of safety, efficacy, stability, accuracy, and predictability with Wavefront Optimized Laser-assisted in situ keratomileusis (LASIK) on hyperopia.

Study Design: Descriptive, analytical study.

Place And Duration Of Study: Armed Forces Institute of Ophthalmology, National University of Medical Sciences, Rawalpindi, Pakistan from August 2013 to June 2018. Read More

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Bowman Layer Onlay Grafting: Proof-of-Concept of a New Technique to Flatten Corneal Curvature and Reduce Progression in Keratoconus.

Cornea 2021 Apr 14. Epub 2021 Apr 14.

Netherlands Institute for Innovative Ocular Surgery, Rotterdam, the Netherlands; Melles Cornea Clinic Rotterdam, the Netherlands; Amnitrans EyeBank Rotterdam, the Netherlands; UAB, Birmingham, AL; and NIIOS-USA, San Diego, CA.

Purpose: The aim of this study was to describe a new surgical technique for flattening the corneal curvature and to reduce progression in eyes with advanced progressive keratoconus (KC) by using Bowman layer (BL) onlay grafting and to report on the preliminary outcomes of this procedure.

Methods: In this prospective interventional case series, 5 patients with advanced progressive KC underwent BL onlay grafting. After removal of the epithelium, a BL graft was placed and "stretched" onto the stroma, and a bandage lens was placed to cover the BL graft. Read More

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Prevalence of Strabismus and Its Associated Factors Among School-Age Children Living in Bahir Dar City: A Community-Based Cross-Sectional Study.

Clin Optom (Auckl) 2021 8;13:103-112. Epub 2021 Apr 8.

Department of Optometry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Introduction: Strabismus is a manifest deviation of the eye that exceeds the control of the fusional mechanism so that the eyes are misaligned under binocular conditions. Its prevalence reaches from 0.7% to 5% globally and 1. Read More

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Establishing Prediction Intervals for the SpeedWheel Acuity Test in Adults and Children.

Klin Monbl Augenheilkd 2021 Apr 14;238(4):488-492. Epub 2021 Apr 14.

Ophthalmology, Universitätsspital Basel Augenklinik, Basel, Switzerland.

Background: The SpeedWheel (SW) test is an objective test of visual acuity (VA) using suppression of the optokinetic nystagmus (OKN). Here, we established prediction intervals of the SW measures compared to Snellen acuity in adults and children.

Subjects And Methods: In this prospective, single center study, subjects aged at least 4 years underwent testing of VA with SW, Landolt-C, and Tumbling-E symbols (Freiburg acuity test: FrACT-C, FrACT-E). Read More

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Surgical outcomes in patients with lamellar macular holes selected based on the optical coherence tomography consensus definition.

Int J Retina Vitreous 2021 Apr 13;7(1):31. Epub 2021 Apr 13.

Ophthalmology Department, AP-HP, Hôpital Lariboisière, Université de Paris, 2 rue Ambroise Paré, 75010, Paris, France.

Purpose: The surgical indication for lamellar macular holes (LMH) is controversial due to a misclassification of different macular diseases. A consensus based on an optical coherence tomography (OCT) definition has recently been suggested. The aim of this study was to investigate the surgical outcomes of patients with LMH selected based on this OCT-based consensus definition. Read More

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Objective and subjective evaluation of trifocal diffractive intraocular Lens after cataract extraction with phacoemulsification: a prospective clinical study.

BMC Ophthalmol 2021 Apr 14;21(1):179. Epub 2021 Apr 14.

Ophthalmology Department, Faculty of Medicine, Alexandria University, Champollion Street, Al Attarin, Alexandria, Egypt.

Background: This study aimed to assess visual outcomes, quality of vision and patients' satisfaction of a trifocal diffractive intraocular lens after cataract surgery with phacoemulsification.

Results: The study included 36 eyes that underwent implantation of trifocal diffractive intraocular lens (IOL). The residual mean postoperative spherical equivalent was - 0. Read More

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Evaluation of acquired color vision deficiency in retinal vein occlusion using the Rabin cone contrast test.

Graefes Arch Clin Exp Ophthalmol 2021 Apr 12. Epub 2021 Apr 12.

Department of Ophthalmology, Shiga University of Medical Science, Seta-Tsukinowacho, Otsu, Shiga, 520-2192, Japan.

Purpose: To investigate acquired color vision deficiency (CVD) using the Rabin cone contrast test (RCCT) in patients with retinal vein occlusion (RVO).

Methods: We retrospectively evaluated 39 patients with macular edema due to RVO who were treated with intravitreal injections of anti-VEGF agents and demonstrated improvement of best-corrected visual acuity to 20/20 Snellen VA or better. The acquired CVD was evaluated by the RCCT and standard pseudo-isochromatic plates-part 2 (SPP-2). Read More

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Ultrastructure of antennal sensilla of Copidosomopsis nacoleiae (Eady) (Hymenoptera: Chalcidoidea: Encyrtidae), a parasitoid of Diaphania angustalis (Snellen) (Lepidoptera: Crambidae).

Microsc Res Tech 2021 Apr 12. Epub 2021 Apr 12.

Guangxi Key Laboratory of Agric-Environment and Agric-Products Safety, College of Agriculture, Guangxi University, Nanning, China.

The antennal sensilla of Copidosomopsis nacoleiae (Eady) (Hymenoptera: Chalcidoidea: Encyrtidae) were observed under scanning and transmission electron microscopy in this study. The antennae of C. nacoleiae are geniculate, and the flagellum is composed of five subsegments in males and six in females. Read More

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Cone Dystrophy Associated with a Novel Variant in the Terminal Codon of the -.

Genes (Basel) 2021 Mar 29;12(4). Epub 2021 Mar 29.

Eye Hospital, University Medical Centre Ljubljana, Grablovičeva 46, 1000 Ljubljana, Slovenia.

Mutations in are associated with rod-cone or cone/cone-rod dystrophy, the latter associated with mutations at the distal end. We describe the phenotype associated with a novel variant in the terminal codon of the c.3457T>A (Ter1153Lysext*38), which results in a C-terminal extension. Read More

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The complete mitochondrial genome of the bagworm from a tea plantation in China, (Lepidoptera: Psychidae).

Mitochondrial DNA B Resour 2021 Mar 15;6(3):875-877. Epub 2021 Mar 15.

Tea Research Institute of Chongqing Academy of Agricultural Science, Chongqing, PR China.

The mitochondrial (mt) genome of Snellen (Psychidae) has been sequenced and annotated. The mt genome has a total length of 15,793 bp, consisting of 13 protein-coding genes, 22 tRNA, two rRNA genes, and an AT-rich control region (GenBank accession no. MN242985). Read More

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Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and Optical Coherence Tomography Analysis.

Ophthalmol Retina 2021 Mar 29. Epub 2021 Mar 29.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To assess visual acuity (VA) outcomes of epiretinal membrane (ERM) surgery following primary rhegmatogenous retinal detachment (RD) repair.

Design: Retrospective, consecutive case series.

Subjects: Eyes undergoing pars plana vitrectomy (PPV) with membrane peel (MP) surgery for ERM following primary RD repair (PPV with or without scleral buckle (SB) and gas tamponade). Read More

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Efficacy of Rituximab Treatment in Vogt-Koyanagi-Harada Disease Poorly Controlled by Traditional Immunosuppressive Treatment.

Ocul Immunol Inflamm 2021 Apr 1:1-6. Epub 2021 Apr 1.

Ocular Immunology Unit, Azienda USL-IRCCS, Reggio Emilia, Italy.

: To evaluate the efficacy of Rituximab (RTX) therapy in patients affected by Vogt-Koyanagi-Harada (VKH) disease poorly controlled by traditional immunosuppressive treatment.: Retrospective case series of recurrent VKH uveitis treated with intravenous RTX between January 2019 and November 2020. All patients were treated with intravenous RTX and underwent complete ophthalmic examination, best-corrected visual acuity (BCVA), fundus photography, subfoveal choroidal thickness (SFCT) measurement on enhanced depth imaging optical-coherence tomography (EDI-OCT), fluorescein, and indocyanine green angiography. Read More

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The number of intracorneal ring segments in asymmetric and central cones.

Eye Vis (Lond) 2021 Mar 30;8(1):10. Epub 2021 Mar 30.

Department of Ophthalmology, Faculty of Medicine, Dokuz Eylul University, Mithatpasa cad, No:1606 Inciraltı Kampusu, Balcova, 35330, Izmir, Turkey.

Background: To compare the results of single versus double intracorneal ring segment (ICRS) (KeraRing) implantation in keratoconus with respect to different cone locations.

Methods: Twenty-two eyes of 18 patients with totally asymmetric cones (20-80% or 0-100% distribution along steep axis) were implanted with single ICRS (Group 1), 38 eyes of 32 patients with central or partially asymmetric cones (50-50% or 40-60% distribution along steep axis) were implanted with double ICRS (Group 2), at a depth of 80% of the site of implantation, in channels created with femtosecond laser device. All patients had uncorrected and corrected distance visual acuities (UDVA and CDVA, respectively) of ≤ 0. Read More

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Timing of Complete Polypoidal Regression Following Intravitreous Aflibercept Treatments in Polypoidal Choroidal Vasculopathy.

Ophthalmol Retina 2021 Mar 26. Epub 2021 Mar 26.

Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, USA.

Purpose: To understand timing of complete polypoidal regression on indocyanine green angiography (ICGA) after aflibercept injections in polypoidal choroidal vasculopathy (PCV).

Design: Multicenter prospective study PARTICIPANTS: Adults with treatment-naïve PCV METHODS: After IRB approval, participants were enrolled and followed for 1 year, Apr 1, 2016 to Dec 30, 2018 at two university-based centers in Thailand. PCV diagnosis was based on the EVEREST criteria. Read More

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Optic Disc Pit Maculopathy: One-Year Outcomes of Pars Plana Vitrectomy with Foveal Sparing Inverted Internal Limiting Membrane Flap.

Cureus 2021 Mar 23;13(3):e14057. Epub 2021 Mar 23.

Department of Retina and Vitreous, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, IND.

Purpose To evaluate the anatomical and visual outcomes in optic disc pit maculopathy following pars plana vitrectomy (PPV) with inverted internal limiting membrane (ILM) flap Methods Retrospective interventional case series of 10 patients diagnosed with serous macular detachment secondary to optic disc pit who underwent PPV with inverted ILM flap and were followed up for a year. Results A p-value of less than 0.05 was defined as statistically significant. Read More

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Associations between visual function and magnitude of refractive error for emmetropic to moderately hyperopic 4- and 5-year-old children in the Vision in Preschoolers - Hyperopia in Preschoolers Study.

Ophthalmic Physiol Opt 2021 May 27;41(3):553-564. Epub 2021 Mar 27.

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Purpose: To evaluate associations between visual function and the level of uncorrected hyperopia in 4- and 5-year-old children without strabismus or amblyopia.

Methods: Children with spherical equivalent (SE) cycloplegic refractive error of -0.75 to +6. Read More

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Conjunctival melanoma: outcomes based on tumour origin in 629 patients at a single ocular oncology centre.

Eye (Lond) 2021 Mar 26. Epub 2021 Mar 26.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.

Purpose: To investigate clinical features and outcomes of conjunctival melanoma classified by tumour origin.

Methods: Retrospective review of conjunctival melanoma patients at a single ocular oncology centre between April 18, 1974 and September 9, 2019. Lesions were divided into three tumour origin groups (primary acquired melanosis [PAM], nevus, and de novo) and clinical features and outcomes were compared. Read More

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