Medicine (Baltimore) 2021 Jan;100(4):e24384
Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University (Army Medical University), 10 Changjiangzhilu, Yuzhong District, Chongqing, China.
Rationale: Anti-IgLON5 disease was first described as a progressive antibody-associated encephalopathy, with multiple non-specific clinical symptoms including sleep dysfunction, bulbar symptoms, progressive supranuclear palsy-like syndrome, cognitive impairment, and a variety of movement disorders. This newly discovered disease presents with unremarkable or unspecific brain magnetic resonance imagings (MRI), and have poor responsiveness to immunotherapy.
Patient Concerns: In this case, a 37-year-old man presented with 4-day history of gait instability, dysarthria, and oculomotor abnormalities. Read More