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Compressive modulus and deformation mechanisms of 3DG foams: Experimental investigation and multiscale modeling.

Nanotechnology 2021 Aug 3. Epub 2021 Aug 3.

Instituto de Ciencia de Materiales de Madrid-ICMM, Consejo Superior de Investigaciones Cientificas, Sor Juana Ines de la Cruz, 3 Campus de Cantoblanco 28049, Madrid, SPAIN, Madrid, Madrid, 28006, SPAIN.

Due to the wide applications of three-dimensional graphene (3DG) foam in bio-sensors, stretchable electronics, and conductive polymer composites, predicting its mechanical behavior is of paramount importance. In this paper, a novel multiscale finite element (FE) model is proposed to predict the compressive modulus of 3DG foams with various densities. It considers the effects of pore size and structure and the thickness of graphene walls on 3DG foams' overall behavior. Read More

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A Multi-Variate framework to assess reliability and discrimination power of Bayesian estimation of Intravoxel Incoherent Motion parameters.

Phys Med 2021 Jul 31;89:11-19. Epub 2021 Jul 31.

Institute of Biomedical Technologies, Italian National Research Council (ITB-CNR), Segrate, Italy.

Purpose: To propose a multivariate multi-step framework for a systematic assessment of the estimation reliability and discriminability of Intravoxel Incoherent Motion (IVIM) model parameters.

Methods: Monte-Carlo simulations were generated on a range of SNRs and in different IVIM combinations considering: i) a dense discretization with 24 b-values; ii) a discretization with 9 b-values. A state-of-the-art Bayesian fitting method was adopted. Read More

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Clinical characteristics and incidences of benign and malignant insulinoma using a national inpatient database in Japan.

J Clin Endocrinol Metab 2021 Aug 3. Epub 2021 Aug 3.

Department of Prevention of Diabetes and Lifestyle-Related Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Context: Insulinoma is the most common pancreatic functional neuroendocrine neoplasm, yet little information on recent clinical practice in patients with insulinoma, especially malignant insulinoma, is available.

Objective: To clarify the characteristics and practice patterns in patients with insulinoma using a national inpatient database.

Methods: Using the Japanese Diagnosis Procedure Combination database, we retrospectively identified patients with insulinoma admitted between 2010 and 2018. Read More

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Surgical outcomes of robot-assisted laparoscopic partial nephrectomy for cystic renal cell carcinoma.

J Robot Surg 2021 Aug 3. Epub 2021 Aug 3.

Department of Urology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

To compare the surgical outcomes of robot-assisted partial nephrectomy (RAPN) between patients with cystic renal cell carcinoma (cRCC) and those with solid RCC (sRCC). We retrospectively analyzed 1065 patients who underwent RAPN between 2013 and 2020 for a pathological diagnosis of RCC. Patients were divided into two groups: cRCC and sRCC. Read More

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Preoperative Breast MRI for Newly Diagnosed Ductal Carcinoma in Situ: Imaging Features and Performance in a Multicenter Setting (ECOG-ACRIN E4112 Trial).

Radiology 2021 Aug 3:204743. Epub 2021 Aug 3.

From the Dept of Radiology, Massachusetts General Hosp, 55 Fruit Street, WAC-240, Boston, MA 02114 (S.H.S.C., C.D.L.); Ctr for Statistical Sciences, Brown Univ School of Public Health, Providence, RI (J.R., I.F.G., B.S.S., C.G.); Dept of Medicine, Northwestern Univ Feinberg School of Medicine, Chicago, Ill (S.A.K.); Dept of Radiology, Univ of Michigan Health System, Ann Arbor, Mich (R.C.); Depts of Pathology and Laboratory Medicine (S.S.B.) and Medicine (K.D.M.), Indiana Univ School of Medicine, Indianapolis, Ind; Dept of Radiology (J.X., H.R.) and Surgery (S.H.J.), Univ of Washington School of Medicine, Seattle, Wash; Dept of Surgery, Tulane Univ School of Medicine, New Orleans, La (R.L.C.); Community Oncology Research Program, Gulf-South National Cancer Inst, New Orleans, La (D.W.S.); Dept of Surgery, Parkview Cancer Inst, Fort Wayne, Ind (L.K.H.); Dept of Surgery, Lankenau Medical Ctr, Wynnewood, Pa (J.L.S.); Dept of Surgery, Mercy Hosp Springfield, Springfield, Mo (J.R.B.); Depts of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC (L.I.W.); Dept of Oncology, Johns Hopkins Univ School of Medicine, Baltimore, Md (A.C.W.); Dept of Medicine (Oncology), Montefiore Medical Center-Weiler Hosp, Bronx, NY (J.A.S.); and Dept of Radiology, Memorial Sloan-Kettering Cancer Ctr, New York, NY (C.E.C.).

Background There are limited data from clinical trials describing preoperative MRI features and performance in the evaluation of mammographically detected ductal carcinoma in situ (DCIS). Purpose To report qualitative MRI features of DCIS, MRI performance in the identification of additional disease, and associations of imaging features with pathologic, genomic, and surgical outcomes from the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network (ECOG-ACRIN) E4112 trial. Materials and Methods Secondary analyses of a multicenter prospective clinical trial from the ECOG-ACRIN Cancer Research Group included women with DCIS diagnosed with conventional imaging techniques (mammography and US), confirmed via core-needle biopsy (CNB), and enrolled between March 2015 and April 2016 who were candidates for wide local excision (WLE) based on conventional imaging and clinical examination results. Read More

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Quantifying risk of injury from usual alcohol consumption: An instrumental variable analysis.

Alcohol Clin Exp Res 2021 Aug 2. Epub 2021 Aug 2.

Alcohol Research Group, Public Health Institute, Emeryville.

Background: There have been numerous studies of roadside accidents among emergency room patients showing elevated risk of injury from acute alcohol consumption, i.e. recent drinking prior to the injury event, with large effect size and a dose-response relationship observed. Read More

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Prevalence and factors associated with menstruation-related school absenteeism among adolescent girls in rural northern Ghana.

BMC Womens Health 2021 Aug 2;21(1):279. Epub 2021 Aug 2.

School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Background: Although menstruation is a normal physiological process that begins in girls during adolescence, it has the potential to negatively impact on the self-esteem and education of girls particularly those from low- and middle-income countries. We investigated the prevalence and factors associated with menstruation-related school absenteeism among adolescent girls in the Talensi district of rural northern Ghana.

Methods: We conducted a cross-sectional survey among 705 adolescent girls aged 12-19 years who had attained menarche. Read More

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Body size and composition of Samoan toddlers aged 18-25 months in 2019.

Ann Hum Biol 2021 Aug 3:1-4. Epub 2021 Aug 3.

Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA.

Background: The " (Beginning of Life)" study is a prospective birth cohort of  = 160 Samoan mother-infant dyads established in 2017-2018. A primary study aim is to explore how a missense variant at rs373863828 impacts growth in early life, given its association with increased body size but lower risk of diabetes in adult Samoans. Here, we examine body size and composition by genotype among toddlers aged 18. Read More

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First report of leaf spot disease caused by on garlic in Korea.

Plant Dis 2021 Aug 2. Epub 2021 Aug 2.

National Institute of Horticultural & Herbal Science, Horticultural and Herbal Crop Environment Division, 100, Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do, Korea (the Republic of), 565-852;

Garlic ( L. cv.) is one of the most popular vegetables grown in Korea due to its high demand from the food industry. Read More

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Intersystem crossing pathways in [5]-, [7]-, and [9]cycloparaphenylenes.

J Chem Phys 2021 Jul;155(4):044301

School of Chemistry, Indian Institute of Science Education and Research, Maruthamala PO, Vithura, Thiruvanathapuram 695551, India.

We analyze the energetics and internal conversion dynamics of singlet and triplet manifolds to identify the possible intersystem crossing pathways in odd-numbered [n]cycloparaphenylenes ([n]CPPs, n = 5, 7, and 9). Quantum wavepacket propagation calculations within the linear vibronic coupling framework suggest that both [5]- and [7]CPPs rapidly relax to S upon populating "bright" higher singlet excited states. The S-S energy decreases with the increase in CPP size, and hence, [9]CPP exhibits a faster S → S internal conversion decay. Read More

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Facile single-step synthesis of [email protected] hybrid nanocomposite by CVD method to remove hazardous pollutants.

Chemosphere 2021 Jul 29;286(Pt 2):131733. Epub 2021 Jul 29.

Faculty of Engineering and Science, Western Norway University of Applied Sciences, Bergen, 5063, Norway.

In the present work, facile preparation of MXenes based nanocomposite (MXene-CNTs) through catalytic chemical vapor deposition (cCVD) was demonstrated. The novel design of two and one-dimensional (2D/1D) MXene-CNTs composites for an extraordinary photocatalytic process for removal of Rhodamine B (RhB) using efficient photocatalytic dye degradations was compared to the performance of pure MXene. The surface morphological behavior of MAX, MXene and MXene-CNTs rational design of surface microstructure CNTs anchored on 2D materials MXene nanosheets product was characterized employing scanning electron microscopy (SEM). Read More

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Mortality amenable to healthcare in Latin American cities: a cross-sectional study examining between-country variation in amenable mortality and the role of urban metrics.

Int J Epidemiol 2021 Aug 2. Epub 2021 Aug 2.

Urban Health Collaborative, Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA.

Background: This study examined the variation in city-level amenable mortality, i.e. mortality due to conditions that can be mitigated in the presence of timely and effective healthcare, in 363 Latin American cities and measured associations between amenable-mortality rates and urban metrics. Read More

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Ethics Consultation in United States Hospitals: Assessment of Training Needs.

J Clin Ethics 2021 ;32(3):1-9

Altarum Institute, Ann Arbor, Michigan USA.

Background: To help inform the development of more accessible, acceptable, and effective ethics consultation (EC) training programs, we conducted an EC training needs assessment, exploring ethics practitioners' opinions on: the relative importance of various EC practitioner competencies; the potential market for EC training (that is, how many individuals would benefit and how much individuals and hospitals would be willing to pay); and the preferred content, format, and characteristics of EC training.

Methods: As part of a multipart study, we surveyed "best informants" who self-identified as the person most actively involved in EC or healthcare ethics in a random sample of 600 U.S. Read More

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January 2021

Evaluating the effects of carbon monoxide releasing molecule-2 against myocardial ischemia-reperfusion injury in ovariectomized female rats.

Naunyn Schmiedebergs Arch Pharmacol 2021 Aug 2. Epub 2021 Aug 2.

Vascular Biology Laboratory, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.

Purpose: Cardioprotective effect of carbon monoxide, a gasotransmitter against myocardial ischemia-reperfusion injury (I/R), is well established in preclinical studies with male rats. However, its ischemic tolerance in post-menopausal animals has not been examined due to functional perturbations at the cellular level.

Methods: The protective role of carbon monoxide releasing molecule-2 (CORM-2) on myocardial I/R was studied in female Wistar rats using the Langendorff apparatus. Read More

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Comparison of Medication Prescribing Before and After the COVID-19 Pandemic Among Nursing Home Residents in Ontario, Canada.

JAMA Netw Open 2021 Aug 2;4(8):e2118441. Epub 2021 Aug 2.

ICES (formerly Institute for Clinical Evaluative Sciences), Toronto, Ontario, Canada.

Importance: COVID-19 has had devastating effects on the health and well-being of older adult residents and health care professionals in nursing homes. Uncertainty about the associated consequences of these adverse effects on the use of medications common to this care setting remains.

Objective: To examine the association between the COVID-19 pandemic and prescription medication changes among nursing home residents. Read More

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Association of Sodium Thiosulfate With Risk of Ototoxic Effects From Platinum-Based Chemotherapy: A Systematic Review and Meta-analysis.

JAMA Netw Open 2021 Aug 2;4(8):e2118895. Epub 2021 Aug 2.

Department of Otolaryngology - Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.

Importance: Platinum-induced ototoxic effects are a significant issue because platinum-based chemotherapy is one of the most commonly used therapeutic medications. Sodium thiosulfate (STS) is considered a potential otoprotectant for the prevention of platinum-induced ototoxic effects that functions by binding the platinum-based agent, but its administration raises concerns regarding the substantial attenuation of the antineoplastic outcome associated with platinum.

Objective: To evaluate the association between concurrent STS and reduced risk of ototoxic effects among patients undergoing platinum-based chemotherapy and to evaluate outcomes, including event-free survival, overall survival, and adverse outcomes. Read More

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Development of MRI-based Axillary Numerical Models and Estimation of Axillary Lymph Nodes Dielectric Properties for Microwave Imaging.

Med Phys 2021 Aug 2. Epub 2021 Aug 2.

Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, 1749-016, Lisbon, Portugal.

Purpose: Microwave Imaging (MWI) has been studied as a complementary imaging modality to improve sensitivity and specificity of diagnosis of Axillary Lymph Nodes (ALNs), which can be metastasised by breast cancer. The feasibility of such a system is based on the dielectric contrast between healthy and metastasised ALNs. However, reliable information such as anatomically realistic numerical models and matching dielectric properties of the axillary region and ALNs, which are crucial to develop MWI systems, are still limited in the literature. Read More

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Robotic Management of Pelvic Lipomatosis-Experience with Difficulties Encountered and the Techniques to Successful Outcomes.

Eur Urol Open Sci 2020 Oct 21;21:33-40. Epub 2020 Sep 21.

Apollo Main Hospitals, Chennai, India.

Background: Pelvic lipomatosis (PL) is a rare condition characterized by diffuse pelvic overgrowth of nonmalignant but infiltrative adipose tissue in perivesical and perirectal space.

Objective: To share our robotic experience and difficulties encountered and suggested techniques to overcome them successfully. It is the first series from India. Read More

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October 2020

Optimization of Genomic Selection to Improve Disease Resistance in Two Marine Fishes, the European Sea Bass () and the Gilthead Sea Bream ().

Front Genet 2021 14;12:665920. Epub 2021 Jul 14.

Université Paris-Saclay, INRAE, AgroParisTech, GABI, Jouy-en-Josas, France.

Disease outbreaks are a major threat to the aquaculture industry, and can be controlled by selective breeding. With the development of high-throughput genotyping technologies, genomic selection may become accessible even in minor species. Training population size and marker density are among the main drivers of the prediction accuracy, which both have a high impact on the cost of genomic selection. Read More

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Genomic Prediction of Resistance to Tar Spot Complex of Maize in Multiple Populations Using Genotyping-by-Sequencing SNPs.

Front Plant Sci 2021 16;12:672525. Epub 2021 Jul 16.

International Maize and Wheat Improvement Center (CIMMYT), El Batan, Mexico.

Tar spot complex (TSC) is one of the most important foliar diseases in tropical maize. TSC resistance could be furtherly improved by implementing marker-assisted selection (MAS) and genomic selection (GS) individually, or by implementing them stepwise. Implementation of GS requires a profound understanding of factors affecting genomic prediction accuracy. Read More

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Patterns of Perioperative Treatment and Survival of Localized, Resected, Intermediate- or High-Grade Soft Tissue Sarcoma: A 2000-2017 Netherlands Cancer Registry Database Analysis.

Sarcoma 2021 22;2021:9976122. Epub 2021 Jul 22.

Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, Netherlands.

Background: Standard therapy for localized soft tissue sarcoma (STS) is wide, limb-sparing resection. For intermediate- or high-grade tumors, (neo)adjuvant therapies are frequently added to the treatment plan. In this study, data from a Dutch nationwide database are used to (1) assess whether perioperative management of STS follows ESMO guidelines, (2) characterize prognostic factors for overall survival (OS), and (3) assess the association between perioperative treatment and survival. Read More

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Effect of Parameterization on Statistical Power and Effect Size Estimation in Latent Growth Modeling.

Authors:
Alan Feingold

Struct Equ Modeling 2021 23;28(4):609-621. Epub 2021 Mar 23.

Oregon Social Learning Center, Eugene, OR.

The difference between groups in their random slopes is frequently examined in latent growth modeling to evaluate treatment efficacy. However, when end centering is used for model parameterization with a randomized design, the difference in the random intercepts is the model-estimated mean difference between the groups at the end of the study, which has the same expected value as the product of the coefficient for the slope difference and study duration. A Monte Carlo study found that (a) the statistical power to detect the treatment effect was greater when determined from the intercept instead of the slope difference, and (b) the standard error of the model-estimated mean difference was smaller when obtained from the intercept difference. Read More

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Deep learning model for forecasting COVID-19 outbreak in Egypt.

Process Saf Environ Prot 2021 Sep 24;153:363-375. Epub 2021 Jul 24.

Environmental Planning and Development Center, Institute of National Planning, (INP), Cairo, Egypt.

The World Health Organization has declared COVID-19 as a global pandemic in early 2020. A comprehensive understanding of the epidemiological characteristics of this virus is crucial to limit its spreading. Therefore, this research applies artificial intelligence-based models to predict the prevalence of the COVID-19 outbreak in Egypt. Read More

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September 2021

Estimating the proportion and IgG antibody response to SARS-CoV-2 in individuals joining a central educational institute from different parts of India by Enzyme-linked immunosorbent assay (ELISA) based serology.

Med J Armed Forces India 2021 Jul 26;77:S366-S372. Epub 2021 Jul 26.

Director & Commandant, Armed Forces Medical College, Pune, India.

Background: Antibody response to SARS-CoV may be estimated to give trends and patterns emerging in a population during an evolving epidemic. The novel coronavirus has opened a new chapter in the history of pandemics and understanding the disease epidemiology.

Methods: The study was a cross-sectional descriptive study. Read More

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Adenoid measurement accuracy: A comparison of lateral skull film, flexible endoscopy, and intraoperative rigid endoscopy (gold standard).

Auris Nasus Larynx 2021 Jul 29. Epub 2021 Jul 29.

Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Objective: To compare the accuracy of lateral skull film, flexible endoscopy, and intraoperative rigid endoscopy in assessment of adenoid size.

Methods: A cross-sectional study was conducted in 43 pediatric patients undergoing ENT surgery from July 2017 to December 2018. All patients underwent preoperative lateral skull film, flexible endoscopy, and intraoperative rigid endoscopy. Read More

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Initiating pancreatic neuroendocrine tumour (pNET) screening in young MEN1 patients: results from the DutchMEN Study Group.

J Clin Endocrinol Metab 2021 Aug 1. Epub 2021 Aug 1.

Department of Endocrine Oncology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.

Context: Non-functioning pancreatic neuroendocrine tumours (NF-pNETs) are highly prevalent and constitute an important cause of mortality in patients with multiple endocrine neoplasia type 1 (MEN1). Still, the optimal age to initiate screening for pNETs is under debate.

Objective: To assess the age of occurrence of clinically relevant NF-pNETs in young MEN1 patients. Read More

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Bivariate binary analysis on composite index of anthropometric failure of under-five children and household wealth-index.

BMC Pediatr 2021 Jul 31;21(1):332. Epub 2021 Jul 31.

Department of Statistics, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Malnutrition is the most common cause of mortality and morbidity of children in low and middle income countries including Ethiopia and household wealth index shares the highest contribution. Thus, in this study it is aimed to conduct bivariate binary logistic regression analysis by accounting the possible dependency of child composite index anthropometric failure and household wealth index.

Methods: In this study the data from Ethiopian Demographic and Health Survey (EDHS) 2016 involved 9411 under five children was considered. Read More

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Proximity of schools to roads and students' academic performance: A cross-sectional study in the Federal District, Brazil.

Environ Res 2021 Jul 28:111770. Epub 2021 Jul 28.

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Investigations of the educational implications of children's exposure to air pollutants at school are crucial to enhance our understanding of the hazards for children. Most of the existing literature is based on studies performed in North America and Europe. Further investigation is required in low- and middle-income countries, where there are important challenges related to public health, transportation, environment, and education sector. Read More

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Distributional consequences of including survivor costs in economic evaluations distributional consequences of survivor costs in economic evaluations.

Health Econ 2021 Jul 30. Epub 2021 Jul 30.

Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, Netherlands.

Medical interventions that increase life expectancy of patients result in additional consumption of non-medical goods and services in 'added life years'. This paper focuses on the distributional consequences across socio-economic groups of including these costs in cost effectiveness analysis. In that context, it also highlights the role of remaining quality of life and household economies of scale. Read More

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Projections of surface air temperature required to sustain permafrost and importance of adaptation to climate change in the Daisetsu Mountains, Japan.

Sci Rep 2021 Jul 30;11(1):15518. Epub 2021 Jul 30.

Earth System Division, National Institute for Environmental Studies, Tsukuba, Japan.

Permafrost is known to occur in high mountainous areas such as the Daisetsu Mountains in Japan, which are located at the southernmost limit of the permafrost distribution in the world. In this study, areas with climatic conditions suitable for sustaining permafrost in the Daisetsu Mountains are projected using bias-corrected and downscaled climate model outputs and statistical relationships between surface air temperatures and permafrost areas. Using freezing and thawing indices, the size of the area in the Daisetsu Mountains where climatic conditions were suitable for permafrost were estimated to be approximately 150 km in 2010. Read More

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